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Peter W. Stacpoole

State University System of Florida

60H-index
308Paper Count
1.3WCitation Count
Published Papers 109
Publication Date
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Pyruvate Dehydrogenase Complex Stimulation With Dichloroacetate May Improve Septic Cardiac Dysfunction
errShock
IF2.9
err2025-12-01
err0
PREAI
errSmith, Lane M.; Lin, Yu Tin; Mertens, Chelsey S.; Zabalawi, Manal L.; Long, David L.; Yoza, Barbara K.; Cox, Anderson O.; Prentice, Boone M.; Stacpoole, Peter W.; Mccall, Charles E.
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SAFETY, PHARMACOKINETICS, AND PHARMACODYNAMIC EFFECTS OF DICHLOROACETATE IN PATIENTS WITH RECURRENT GLIOBLASTOMA
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
PREAI
errDirain, Carolyn; Sambasivan, Priya; Shori, Puranjay; Liyanarachchi, Himashi; Fisher, Joy; Iacoboni, Michaella; Holdhoff, Matthias; Schreck, Karisa; Tatter, Stephen; Strowd, Roy; Grossman, Stuart; Stacpoole, Peter
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Should the “mitochondrial cocktail” be a default option? An opinion
errMolecular Genetics and Metabolism
IF3.5
err2025-10-24
err0
PREAI
errPeter W. Stacpoole; Stephen D. Cederbaum
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errSave
Extension of lifespan by epicatechin, halofuginone and mitoglitazone in male but not female genetically heterogeneous mice
errGeroScience
IF5.4
err2025-09-19
err0
errOAAI
errRandy Strong; James F. Nelson; Molly A. Bogue; Jerry R. Colca; Martin Denzel; Vivian Diaz; Brian N. Finck; Vadim N. Gladyshev; Steve Horvath; Nisi Jiang; Tracy Keller; Rolf F. Kletzien; Ron Korstanje; Navasuja Kumar; Christiaan Leeuwenburgh; Elizabeth Fernandez; Andrzej Galecki; Brett Ginsburg; Melissa Han; Catherine Kaczorowski; Scott Leiser; Marisa Lopez-Cruzan; Ken Raj; Peter C. Reifsnyder; Nadia A. Rosenthal; Susanna Rosi; Anastasia Shindyapina; Peter Stacpoole; Adam B. Salmon; Alexander Tyshkovskiy; Peter Walter; Malcolm Whitman; Richard A. Miller; David E. Harrison
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The pyruvate dehydrogenase complex at the epigenetic crossroads of acetylation and lactylation
errMOLECULAR GENETICS AND METABOLISM
IF3.5
err2024-09-01
err2
PREAI
errStacpoole, Peter W.; Dirain, Carolyn O.
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Clinical physiology and pharmacology of GSTZ1/MAAI
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2023-11-01
err3
PREAI
errStacpoole, Peter W.
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errSave
The pyruvate dehydrogenase complex: Life's essential, vulnerable and druggable energy homeostat
errMitochondrion
IF4.5
err2023-05-01
err22
errOAAI
errStacpoole, Peter W.; McCall, Charles E.
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errSave
In-vivo magnetic resonance spectroscopy of lactate as a non-invasive biomarker of dichloroacetate activity in cancer and non-cancer central nervous system disorders
errFRONTIERS IN ONCOLOGY
IF3.3
err2023-03-17
err5
errOAAI
errKamson, David O.; Chinnasamy, Viveka; Grossman, Stuart A.; Bettegowda, Chetan; Barker, Peter B.; Stacpoole, Peter W.; Oeltzschner, Georg
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CURRENT STATUS OF THE PHASE 3 TRIAL OF DICHLOROACETATE (DCA) FOR PYRUVATE DEHYDROGENASE COMPLEX DEFICIENCY (PDCD)
errMOLECULAR GENETICS AND METABOLISM
IF3.5
err2023-03-01
err0
PREAI
errStacpoole, Peter W.; Dorsey, Kathy
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Sepsis, pyruvate, and mitochondria energy supply chain shortage
errJOURNAL OF LEUKOCYTE BIOLOGY
IF3.1
err2022-07-22
err16
errOAAI
errMcCall, Charles E.; Zhu, Xuewei; Zabalawi, Manal; Long, David; Quinn, Matthew A.; Yoza, Barbara K.; Stacpoole, Peter W.; Vachharajani, Vidula
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Dichloroacetate improves systemic energy balance and feeding behavior during sepsis
errJCI INSIGHT
IF6.1
err2022-06-22
err15
errOAAI
errOh, Tae Seok; Zabalawi, Manal; Jain, Shalini; Long, David; Stacpoole, Peter W.; McCall, Charles E.; Quinn, Matthew A.
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errSave
Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction
errELIFE
IF0
err2021-02-22
err47
errOAAI
errMainali, Rabina; Zabalawi, Manal; Long, David; Buechler, Nancy; Quillen, Ellen; Key, Chia-Chi; Zhu, Xuewei; Parks, John S.; Furdui, Cristina; Stacpoole, Peter W.; Martinez, Jennifer; McCall, Charles E.; Quinn, Matthew A.
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Induction of Glutathione Transferases and NAD(P)H Quinone Dehydrogenase 1 in Rats Dosed with Dichloroacetate
errFASEB JOURNAL
IF4.2
err2020-04-18
err0
PREAI
errSquirewell, Edwin; Mareus, Ricky; Mohamed, Mayar; Laguerre, Aude; Horne, Lloyd; Stacpoole, Peter; James, Margaret
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Mitochondrial diseases in North America: An analysis of the NAMDC Registry
errNEUROLOGY-GENETICS
IF3.7
err2020-04-01
err38
errOAAI
errBarca, Emanuele; Long, Yuelin; Cooley, Victoria; Schoenaker, Robert; Emmanuele, Valentina; DiMauro, Salvatore; Cohen, Bruce H.; Karaa, Amel; Vladutiu, Georgirene D.; Haas, Richard; Van Hove, Johan L. K.; Scaglia, Fernando; Parikh, Sumit; Bedoyan, Jirair K.; DeBrosse, Susanne D.; Gavrilova, Ralitza H.; Saneto, Russell P.; Enns, Gregory M.; Stacpoole, Peter W.; Ganesh, Jaya; Larson, Austin; Zolkipli-Cunningham, Zarazuela; Falk, Marni J.; Goldstein, Amy C.; Tarnopolsky, Mark; Gropman, Andrea; Camp, Kathryn; Krotoski, Danuta; Engelstad, Kristin; Rosales, Xiomara Q.; Kriger, Joshua; Grier, Johnston; Buchsbaum, Richard; Thompson, John L. P.; Hirano, Michio
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Stimulating pyruvate dehydrogenase complex reduces itaconate levels and enhances TCA cycle anabolic bioenergetics in acutely inflamed monocytes
errJOURNAL OF LEUKOCYTE BIOLOGY
IF3.1
err2020-01-02
err29
errOAAI
errZhu, Xuewei; Long, David; Zabalawi, Manal; Ingram, Brian; Yoza, Barbara K.; Stacpoole, Peter W.; McCall, Charles E.
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The changing landscape of clinical trials for mitochondrial diseases: 2011 to present
errMitochondrion
IF4.5
err2020-01-01
err6
errOAAI
errKhayat, Delia; Kurtz, Tracie L.; Stacpoole, Peter W.
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Mitochondrial Glutathione Transferase Zeta 1 Is Inactivated More Rapidly by Dichloroacetate than the Cytosolic Enzyme in Adult and Juvenile Rat Liver
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2019-09-16
err4
errOAAI
errSmeltz, Marci G.; Hu, Zhiwei; Zhong, Guo; Jahn, Stephan C.; Rowland-Faux, Laura; Horne, Lloyd P.; Stacpoole, Peter W.; James, Margaret O.
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Development of a novel observer reported outcome tool as the primary efficacy outcome measure for a rare disease randomized controlled trial
errMitochondrion
IF4.5
err2018-09-01
err11
errOAAI
errStacpoole, Peter W.; Shuster, Jonathan; (Seamus) Thompson, John L. P.; Prather, Robert A.; Lawson, Lee Ann; Zou, Baiming; Buchsbaum, Richard; Nixon, Sara Jo
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Pyruvate dehydrogenase complex stimulation promotes immunometabolic homeostasis and sepsis survival
errJCI INSIGHT
IF6.1
err2018-08-09
err52
errOAAI
errMcCall, Charles E.; Zabalawi, Manal; Liu, Tiefu; Martin, Ayana; Long, David L.; Buechler, Nancy L.; Arts, Rob J. W.; Netea, Mihai; Yoza, Barbara K.; Stacpoole, Peter W.; Vachharajani, Vidula
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Regulation of dichloroacetate biotransformation in rat liver and extrahepatic tissues by GSTZ1 expression and chloride concentration
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2018-06-01
err7
errOAAI
errJahn, Stephan C.; Smeltz, Marci G.; Hu, Zhiwei; Rowland-Faux, Laura; Zhong, Guo; Lorenzo, Ryan J.; Cisneros, Katherine V.; Stacpoole, Peter W.; James, Margaret O.
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Research Directions

No research directions
Co-authors
Cooperation Journals
M
Mihai G. Netea
H-index: 183 · Papers: 1.7K
S
Steve Horvath
H-index: 150 · Papers: 941
M
Mark A. Tarnopolsky
H-index: 129 · Papers: 889
P
Patrick F. Chinnery
H-index: 128 · Papers: 937
V
Vadim N. Gladyshev
H-index: 123 · Papers: 786
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