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Olivia M. Merkel

ludwig-maximilians universität münchen

50H-index
219Paper Count
7.7KCitation Count
Published Papers 113
Publication Date
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Utilizing chitosan nanoparticles for the delivery of biologics to the brain via intranasal route
errMaterials Today Advances
IF8
err2026-07-07
err0
errOAAI
errBettina Gabold; Irene Gialdini; Igor Khalin; Antonietta Greco; Adrian Kromer; Xiaoxuan Wang; Lea-Adriana Barlang; Andreas Popp; Christian L. Ried; Thomas Merdan; Nikolaus Plesnila; Don C. Lamb; Olivia M. Merkel
errShare
errSave
mRNA Delivery by Lipoamino Fatty Acid–Peptide Polyplexes in Different Lung Cell Models and Lungs
errPolymers
IF4.9
err2026-05-31
err0
errOAAI
errSophie Thalmayr; Joschka Müller; Vivien Polewka; Irene Gialdini; Anny Nguyen; Christian Dohmen; Don C. Lamb; Olivia M. Merkel; Ernst Wagner
errShare
errSave
Meta-Learning as a Promising Strategy for Lipid Nanoparticle Optimization and Ionizable Lipid Discovery
errNano Letters
IF9.1
err2026-05-21
err0
errOAAI
errFelix Sieber-Schäfer; Lasse Hagedorn; Leon Reger; Katharina Möbius; Benjamin Winkeljann; Olivia M. Merkel
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errSave
Chemical topology of lipo-amino fatty acid mRNA carriers triggers distinct lipid bulk phases and endosomal escape mechanisms
errMaterials Today
IF22
err2026-04-27
err0
errOAAI
errMelina Grau; Ekaterina Kostyurina; Johanna Seidl; Nora Martini; Benjamin Winkeljann; Olivia M. Merkel; Joachim O. Rädler; Ernst Wagner
errShare
errSave
New insights into the intrinsic tryptophan fluorescence emission spectra of IgG antibodies and the impact of protein unfolding and aggregation
errEuropean Journal of Pharmaceutics and Biopharmaceutics
IF4.3
err2026-04-18
err0
PREAI
errLennart Brack; Jonas Binder; Irene Gialdini; Don C. Lamb; Wolfgang Friess; Olivia M. Merkel; Rudolf Schroeder
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errSave
Drug Product Development of Lipid Nanoparticle-Based mRNA Therapeutics and Vaccines
errWIREs Nanomedicine and Nanobiotechnology
IF0
err2026-02-27
err0
errOAAI
errGideon Kersten; Eleonora Cerasoli; Bruce Kerwin; Olivia M. Merkel; Andrea Hawe
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errSave
Hydrophobic Refinement of Polarity-Switchable Lipo-Xenopeptides Modulates Endosomal Escape and Enhances mRNA Delivery In Vitro and In Vivo
errJournal of the American Chemical Society
IF15.6
err2026-02-25
err0
PREAI
errTobias Burghardt; Sophie Thalmayr; Lennart Obeser; Jana Pöhmerer; Mina Yazdi; Miriam Höhn; Matthias Völkl; Felix Sieber-Schäfer; Stefan Zahler; Olivia M. Merkel; Daniel Merk; Ernst Wagner
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errSave
Modulating mRNA carrier efficacy through the molecular catwalk of ionizable nitrogens in lipidic domains
errJournal of Colloid and Interface Science
IF9.7
err2026-01-24
err0
errOAAI
errMelina Grau; Nora Martini; Sophie Thalmayr; Miriam Höhn; Olivia M. Merkel; Benjamin Winkeljann; Ernst Wagner
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errSave
Optimized lipid nanoparticles for pulmonary delivery of CRISPR/Cas9 targeting KRAS G12S in lung cancer
errJournal of Controlled Release
IF11.5
err2026-01-06
err0
errOAAI
errMoritz Marschhofer; Siyu Chen; Müge Molbay; Benjamin Winkeljann; Ersilia Villano; Corinne Giancaspro; Alexandra Kourou; Otto Berninghausen; Susanne Rieder; Charlotte Ungewickell; Roland Beckmann; Bastian Popper; Ana Maria Torres; Anxo Vidal; Olivia M. Merkel; Simone P. Carneiro
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errSave
Engineering access to the brain: nanotechnologies at the interface of delivery, neurology, and immunotherapy
errDrug Delivery and Translational Research
IF5.5
err2026-01-06
err0
errOAAI
errOlivia M. Merkel; Shang-Hsiu Hu; Cristina Fornaguera
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errSave
QbD product development: rapid optimization and scale-up of PBAE-based siRNA delivery via DoE-guided microfluidics
errRSC Pharmaceutics
IF0
err2026-01-01
err0
errOAAI
errKromer, Adrian P. E.; Eller, Laetitia J. M.; Jurgens, David C.; Merkel, Olivia M.
errShare
errSave
Understanding excipient interactions unlocks untapped potential of RNA-lipid nanoparticles in dry powder formulations for local pulmonary delivery
errJournal of Controlled Release
IF11.5
err2025-12-12
err0
errOAAI
errNora Martini; Leonie Deßloch; Taras Sych; Otto Berninghausen; J. Merl-Pham; Sjoerd Dijkstra; Simone P. Carneiro; Marion Frankenberger; Roland Beckmann; Jürgen Behr; Gabriele Matschiner; Christine Schuberth-Wagner; A. Önder Yildirim; David C. Jürgens; Erdinc Sezgin; Olivia M. Merkel; Benjamin Winkeljann
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errSave
Impact of Formulation and Process Parameters on the Stability and Bioactivity of RNA-Loaded Lipid Nanoparticles during Nebulization
errEuropean Journal of Pharmaceutical Sciences
IF4.7
err2025-11-19
err0
errOAAI
errKatrin F. Wiebe; Stefan Schneid; Werner Hoheisel; Wolfgang Frieß; Olivia M. Merkel
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errSave
From Bits to Bonds: High-Throughput Virtual Screening of Ribonucleic Acid Nanocarriers Using a Combinatorial Approach of Machine Learning and Molecular Dynamics
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2025-11-01
err0
PREAI
errSieber-Schafer, Felix; Binder, Jonas; Munchrath, Tim; Steinegger, Katharina M.; Jiang, Min; Winkeljann, Benjamin; Friess, Wolfgang; Merkel, Olivia M.
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errSave
Design of an Injectable and Bioerodible Supramolecular Hydrogel as a Local Nucleic Acid Delivery System
errACS APPLIED POLYMER MATERIALS
IF4.7
err2025-11-01
err0
PREAI
errCoppola, Paola Grillo; Kromer, Adrian Philipp Eckart; Boffito, Monica; Winkeljann, Benjamin; Ciardelli, Gianluca; Merkel, Olivia M.
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errSave
Development of Trastuzumab-coupled, siRNA encapsulating mPolyplexes targeting HER2 overexpressing cancer cells
errEuropean Journal of Pharmaceutics and Biopharmaceutics
IF4.3
err2025-10-28
err0
errOAAI
errJoschka T. Müller; Salvatore Caruso; Anny Nguyen; David C. Jürgens; Adrian P.E. Kromer; Sahana Sheshachala; Nathan B.P. Adams; Olivia M. Merkel
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errSave
Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC
errFrontiers in Immunology
IF5.9
err2025-10-24
err0
errOAAI
errLina Ouologuem; Anna Kübler; Sarah Ouologuem; Amar Hadzic; Jan B. Stöckl; Anna Chiara Siciliano; Stefania Forciniti; Salvatore Nigro; Helena Iuele; Valentina Onesto; Anny Nguyen; Dana Matzek; Carla Abrahamian; Christian Grimm; Bastian Popper; Giuseppe Gigli; Loretta L. del Mercato; Olivia M. Merkel; Thomas Fröhlich; Sebastian Theurich; Karin Bartel
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errSave
Spermine-Based Nanocarriers for siRNA Delivery in Fibroblast-Driven Diseases: A Proof-of-Concept Study
errMACROMOLECULAR CHEMISTRY AND PHYSICS
IF2.7
err2025-10-01
err0
PREAI
errReger, Leon; Giglio, Alessia; Hommel, Johannes; Chiesa, Enrica; Sgarbi, Elisa; Marchini, Gessica; Pizzirani, Daniela; Pinto Carneiro, Simone; Genta, Ida; Adams, Friederike; Merkel, Olivia M.
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errSave
Photothermally Powered 3D Microgels Mechanically Regulate Mesenchymal Stem Cells Under Anisotropic Force
errAdvanced Materials
IF26.8
err2025-09-24
err0
errOAAI
errChen Wang; Nergishan İyisan; Philipp Harder; Valentin H. K. Fell; Viktorija Kozina; Hendrik Dietz; Olivia M. Merkel; Berna Özkale
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errSave
Recent advances in the nanoplatform-mediated delivery of gene editing technologies to the lungs
errNanomedicine
IF3.9
err2025-08-21
err0
PREAI
errMoritz Marschhofer; Simone P. Carneiro; Olivia M. Merkel
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
R
Róbert Langer
H-index: 262 · Papers: 2.0K
刘豫 cover
刘豫 (Yu Liu)
H-index: 116 · Papers: 2.7K
P
Pieter R. Cullis
H-index: 108 · Papers: 478
R
Rainer Müller
H-index: 105 · Papers: 625
M
Mark R. Prausnitz
H-index: 105 · Papers: 443
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