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L

Lori L. Isom

university of michigan

67H-index
207Paper Count
1.4WCitation Count
Published Papers 93
Publication Date
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Cardiac remodeling and arrhythmia in a mouse model of Depdc5 haploinsufficiency
errEpilepsia
IF6.6
err2026-04-09
err0
errOAAI
errRoberto Ramos-Mondragon; Shuyun Wang; Qinghua Liu; Chunling Chen; Alexander M. Greiner; Abigail M. Marx; Maya Shih; Jack M. Parent; Barry London; Lori L. Isom
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Unraveling SUDEP: Mechanisms of Seizure-Induced Cardiac and Respiratory Impairment
errEpilepsy Currents
IF6.3
err2026-01-21
err0
PREAI
errIan C. Wenker; Brian K. Gehlbach; Lori L. Isom; Brian J. Dlouhy; David S. Auerbach; Jamie L. Maguire; Carie R. Boychuk
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errSave
Dravet syndrome therapeutics: where are we, what works, and what's next?
errEXPERT OPINION ON PHARMACOTHERAPY
IF2.7
err2025-11-01
err0
PREAI
errBagchi, Vikram A.; Ziobro, Julie; Isom, Lori L.
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errSave
Mitochondrial NOX4 Drives Atrial Fibrillation via Redox-Dependent Structural Remodeling and Fibrosis
errFree Radical Biology and Medicine
IF8.2
err2025-11-01
err0
PREAI
errRoberto Ramos Mondragon; Aleksandr E. Vendrov; Andrey Lozhkin; Eric N. Jimenez Vazquez; Shuyun Wang; Takayuki Hayami; Omer Bernfeld; Justus M. Anumonwo; Lori L. Isom; Nageswara R. Madamanchi
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Ataxia and cerebellar hypoexcitability in a mouse model of SCN1B-linked Dravet syndrome
errJCI INSIGHT
IF6.1
err2025-09-09
err0
errOAAI
errYuan, Yukun; O'Malley, Heather A.; Winters, Jesse J.; Lavado, Alfonso; Denomme, Nicholas S.; Bakshi, Shreeya; Hodges, Samantha L.; Lopez-Santiago, Luis; Chen, Chunling; Isom, Lori L.
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Altered cardiac excitability and arrhythmia in models of SCN1B-linked developmental and epileptic encephalopathy
errJCI INSIGHT
IF6.1
err2025-09-09
err1
errOAAI
errRamos-Mondragon, Roberto; Wang, Shuyun; Edokobi, Nnamdi; Liu, Qinghua; Qiao, Xiaotan; Shih, Maya; Dang, Louis T.; Tsan, Yao-Chang; Sterbova, Katalin; Helms, Adam S.; Weckhuysen, Sarah; Lopez-Santiago, Luis F.; Parent, Jack M.; Isom, Lori L.
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NOX4-driven mitochondrial oxidative stress in aging promotes myocardial remodeling and increases susceptibility to ventricular tachyarrhythmia
errFREE RADICAL BIOLOGY AND MEDICINE
IF8.2
err2025-06-16
err0
PREAI
errMondragon, Roberto Ramos; Wang, Shuyun; Stevenson, Mark D.; Lozhkin, Andrey; Vendrov, Aleksandr E.; Isom, Lori L.; Runge, Marschall S.; Madamanchi, Nageswara R.
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Neuromodulation of voltage-gated sodium channels by Gβ1γ2 subunits: Implications for GNB1-linked encephalopathy
errNeurobiology of Disease
IF5.6
err2025-06-05
err0
errOAAI
errNicholas Denomme; Samantha L. Hodges; Luis Lopez-Santiago; Yukun Yuan; Julie M. Ziobro; Joe Minton; Chunling Chen; Yan Chen; Jacob M. Hull; James Offord; Alan V. Smrcka; Lori L. Isom
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errSave
No more nonsense: evaluating poison exons as therapeutic targets in neurodevelopmental disorders
errCURRENT OPINION IN GENETICS & DEVELOPMENT
IF3.6
err2025-06-01
err0
PREAI
errBakshi, Shreeya; Isom, Lori L.
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errSave
Special section: William A. Catterall Memorial Issue e Mechanisms of Electrical Excitability
errMOLECULAR PHARMACOLOGY
IF3
err2025-06-01
err0
PREAI
errIsom, Lori L.
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errSave
Ontology accelerates few-shot learning capability of large language model: A study in extraction of drug efficacy in a rare pediatric epilepsy
errINTERNATIONAL JOURNAL OF MEDICAL INFORMATICS
IF4.1
err2025-05-23
err0
errOAAI
errGolnari, Pedram; Prantzalos, Katrina; Hood, Veronica; Meskis, Mary Anne; Isom, Lori L.; Wilcox, Karen; Parent, Jack M.; Lal, Dennis; Lhatoo, Samden D.; Goodkin, Howard P.; Wirrell, Elaine C.; Knupp, Kelly G.; Patel, Manisha; Loeb, Jeffrey A.; Sullivan, Joseph E.; Harte-Hargrove, Lauren; Fureman, Brandy E.; Buchhalter, Jeffrey; Sahoo, Satya S.
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Memorial Tribute to William Albert Catterall (1946-2024)
errMOLECULAR PHARMACOLOGY
IF3
err2024-07-01
err0
errOAAI
errIsom, Lori L.
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errSave
Deriving early single-rosette brain organoids from human pluripotent stem cells
errSTEM CELL REPORTS
IF5.1
err2023-12-01
err6
errOAAI
errTidball, Andrew M.; Niu, Wei; Ma, Qianyi; Takla, Taylor N.; Walker, J. Clayton; Margolis, Joshua L.; Mojica-Perez, Sandra P.; Sudyk, Roksolana; Deng, Lu; Moore, Shannon J.; Chopra, Ravi; Shakkottai, Vikram G.; Murphy, Geoffrey G.; Yuan, Yukun; Isom, Lori L.; Li, Jun Z.; Parent, Jack M.
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Epilepsy and sudden unexpected death in epilepsy in a mouse model of human SCN1B-linked developmental and epileptic encephalopathy
errBRAIN COMMUNICATIONS
IF4.5
err2023-10-20
err8
errOAAI
errChen, Chunling; Ziobro, Julie; Robinson-Cooper, Larissa; Hodges, Samantha L.; Chen, Yan; Edokobi, Nnamdi; Lopez-Santiago, Luis; Habig, Karl; Moore, Chloe; Minton, Joe; Bramson, Sabrina; Scheuing, Caroline; Daddo, Noor; Sterbova, Katalin; Weckhuysen, Sarah; Parent, Jack M.; Isom, Lori L.
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Antisense oligonucleotides restore excitability, GABA signalling and sodium current density in a Dravet syndrome model
errBRAIN
IF11.7
err2023-10-10
err8
PREAI
errYuan, Yukun; Lopez-Santiago, Luis; Denomme, Nicholas; Chen, Chunling; O'Malley, Heather A.; Hodges, Samantha L.; Ji, Sophina; Han, Zhou; Christiansen, Anne; Isom, Lori L.
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errSave
NADPH Oxidases and Oxidative Stress in the Pathogenesis of Atrial Fibrillation
errANTIOXIDANTS
IF6.6
err2023-10-06
err15
errOAAI
errRamos-Mondragon, Roberto; Lozhkin, Andrey; Vendrov, Aleksandr E.; Runge, Marschall S.; Isom, Lori L.; Madamanchi, Nageswara R.
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Heterogeneity of voltage gated sodium current density between neurons decorrelates spiking and suppresses network synchronization in Scn1b null mouse models
errSCIENTIFIC REPORTS
IF3.9
err2023-06-01
err1
errOAAI
errHull, Jacob M.; Denomme, Nicholas; Yuan, Yukun; Booth, Victoria; Isom, Lori L.
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errSave
Hidden behavioral fingerprints in epilepsy
errNEURON
IF15
err2023-05-01
err7
errOAAI
errGschwind, Tilo; Zeine, Ayman; Raikov, Ivan; Markowitz, Jeffrey E.; Gillis, Winthrop F.; Felong, Sylwia; Isom, Lori L.; Datta, Sandeep Robert; Soltesz, Ivan
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Therapeutic Potential of Targeting Regulated Intramembrane Proteolysis Mechanisms of Voltage-Gated Ion Channel Subunits and Cell Adhesion Molecules
errPHARMACOLOGICAL REVIEWS
IF17.3
err2022-10-01
err1
errOAAI
errHodges, Samantha L.; Bouza, Alexandra A.; Isom, Lori L.
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Subcellular dynamics and functional activity of the cleaved intracellular domain of the Na+ channel β1 subunit
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-08-01
err6
errOAAI
errHaworth, Alexander S.; Hodges, Samantha L.; Capatina, Alina L.; Isom, Lori L.; Baumann, Christoph G.; Brackenbury, William J.
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Research Directions

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Co-authors
Cooperation Journals
W
William A. Catterall
H-index: 162 · Papers: 652
B
Ben A. Barres
H-index: 124 · Papers: 242
M
Matthias Nahrendorf
H-index: 119 · Papers: 465
M
Melitta Schachner
H-index: 115 · Papers: 676
E
Eleonora Aronica
H-index: 115 · Papers: 766
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