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C

Claus Storgaard Sørensen

university of copenhagen

46H-index
114Paper Count
8.5KCitation Count
Published Papers 61
Publication Date
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Functional assays for BRCA1 and BRCA2 variant analysis: new tools and their applications
errnpj Breast Cancer
IF7.6
err2026-04-15
err0
errOAAI
errMuthiah Bose; Elangoli Ebrahimkutty Faseela; Maria Rossing; Claus Storgaard Sørensen
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Hemizygous loss of helicases promotes genomic instability and cancer development
errScience Advances
IF12.5
err2026-02-20
err0
errOAAI
errKarolin Voßgröne; Francesco Favero; Krushanka Kashyap; Francisco G. Rodríguez-González; André V. Olsen; Xin Li; Balca R. Mardin; Joachim Weischenfeldt; Claus S. Sørensen
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Large-scale meta-analysis and precision functional assays identify FANCM regions in which PTVs confer different risks for ER-negative and triple-negative breast cancer
errThe Breast
IF0
err2025-10-30
err0
errOAAI
errAmandine Billaud; Gisella Figlioli; Clémence Mooser; Irene Casamassima; Violette Azzoni; Jahnavi Srivatsa; Mara Colombo; Laura Caleca; Thomas U. Ahearn; Irene L. Andrulis; Antonis C. Antoniou; Matthias W. Beckmann; Sabine Behrens; Marina Bermisheva; Natalia V. Bogdanova; Manjeet K. Bolla; Bernardo Bonanni; Thomas Brüning; Nicola J. Camp; Archie Campbell; Jose E. Castelao; Melissa H. Cessna; Jenny Chang-Claude; Kamila Czene; Joe Dennis; Peter Devilee; Thilo Dörk; Alison M. Dunning; Mikael Eriksson; D.Gareth Evans; Peter A. Fasching; Jonine D. Figueroa; Marike Gabrielson; Manuela Gago-Dominguez; Anna González-Neira; Pascal Guénel; Andreas Hadjisavvas; Eric Hahnen; Ute Hamann; Peter Hillemanns; Antoinette Hollestelle; Maartje J. Hooning; Reiner Hoppe; Anthony Howell; Anna Jakubowska; Vessela N. Kristensen; Jan Lubiński; Michael Lush; Siranoush Manoukian; Dimitrios Mavroudis; Roger L. Milne; Anna Marie Mulligan; William G. Newman; Nadia Obi; Mihalis I. Panayiotidis; Guillermo Pita; Muhammad U. Rashid; Valerie Rhenius; Emmanouil Saloustros; Elinor J. Sawyer; Rita K. Schmutzler; Mitul Shah; Melissa C. Southey; Amanda B. Spurdle; Ian Tomlinson; Thérèse Truong; Qin Wang; Camilla Wendt; Paul L. Auer; Nicholas J. Boddicker; Clara Bodelon; Elizabeth S. Burnside; Fei Chen; Fergus J. Couch; Susan M. Domchek; Heather A. Eliassen; Christopher Haiman; James M. Hodge; Chunling Hu; Hongyan Huang; Sara Lindstrom; Maria Elena Martinez; Katherine L. Nathanson; Susan L. Neuhausen; Katie M. O’Brien; Janet E. Olson; Julie R. Palmer; Alpa V. Patel; Kathryn J. Ruddy; Dale P. Sandler; Lauren R. Teras; Clarice R. Weinberg; Jeffrey N. Weitzel; Stacey J. Winham; Siddhartha Yadav; Song Yao; Gary Zirpoli; Marketa Janatova; Zdenek Kleibl; Petra Kleiblova; Jana Soukupova; Qihong Zhao; Lisa Devereux; Paul A. James; Ian G. Campbell; Tu Nguyen-Dumont; James G. Dowty; Nadine Andrieu; Fabienne Lesueur; Dominique Stoppa-Lyonnet; Miguel de la Hoya; Paolo Radice; Claus Storgaard Sørensen; Paolo Peterlongo
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Distinct roles of the two BRCA2 DNA-binding domains in DNA damage repair and replication fork preservation
errCELL REPORTS
IF6.9
err2025-05-01
err0
errOAAI
errNeal, Francisco E.; Li, Wenjing; Uhrig, Mollie E.; Katz, Jeffrey N.; Syed, Shahrez; Sharma, Neelam; Dutta, Arijit; Burma, Sandeep; Hromas, Robert; Mazin, Alexander, V; Dray, Eloise; Libich, David S.; Olsen, Shaun K.; Wasmuth, Elizabeth, V; Zhao, Weixing; Sorensen, Claus S.; Wiese, Claudia; Kwon, Youngho; Sung, Patrick
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errSave
Nuclear N-WASP Induces Actin Polymerization in the Nucleus with Cortactin as an Essential Factor
errCELLS
IF5.2
err2025-01-06
err0
errOAAI
errJiang, Xin; Mohapatra, Purusottam; Rossing, Maria; Zheng, Wenqian; Zbodakova, Olga; Thatte, Jayashree Vijay; Sorensen, Claus Storgaard; Phan, Thu Han Le; Brakebusch, Cord
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errSave
Pushing the boundaries of radiotherapy-immunotherapy combinations: highlights from the 7th immunorad conference
errONCOIMMUNOLOGY
IF6.3
err2024-12-18
err0
errOAAI
errLaurent, Pierre-Antoine; Andre, Fabrice; Bobard, Alexandre; Deandreis, Desiree; Demaria, Sandra; Depil, Stephane; Eichmueller, Stefan B.; Fernandez-Palomo, Cristian; Foijer, Floris; Galluzzi, Lorenzo; Galon, Jerome; Guckenberger, Matthias; Harrington, Kevin J.; Herrera, Fernanda G.; Huber, Peter E.; Italiano, Antoine; Karam, Sana D.; Kroemer, Guido; Lambin, Philippe; Leuschner, Carola; Mantovani, Alberto; Meylan, Etienne; Mondini, Michele; Pittet, Mikael J.; Pouget, Jean-Pierre; Remon, Jordi; Sorensen, Claus S.; Sotiriou, Christos; Vanpouille-Box, Claire; Weichselbaum, Ralph R.; Welsh, James W.; Zitvogel, Laurence; Formenti, Silvia C.; Deutsch, Eric
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errSave
H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours
errNATURE COMMUNICATIONS
IF15.7
err2024-05-24
err4
errOAAI
errDibitetto, Diego; Liptay, Martin; Vivalda, Francesca; Dogan, Huelya; Gogola, Ewa; Gonzalez Fernandez, Martin; Duarte, Alexandra; Schmid, Jonas A.; Decollogny, Morgane; Francica, Paola; Przetocka, Sara; Durant, Stephen T.; Forment, Josep V.; Klebic, Ismar; Siffert, Myriam; de Bruijn, Roebi; Kousholt, Arne N.; Marti, Nicole A.; Dettwiler, Martina; Sorensen, Claus S.; Tille, Jean-Christophe; Undurraga, Manuela; Labidi-Galy, Intidhar; Lopes, Massimo; Sartori, Alessandro A.; Jonkers, Jos; Rottenberg, Sven
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errSave
PALB2-mutated human mammary cells display a broad spectrum of morphological and functional abnormalities induced by increased TGFβ signaling
errCELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
err2024-04-10
err1
errOAAI
errTuppurainen, Hanna; Laurila, Niina; Natynki, Marjut; Eshraghi, Leila; Tervasmaki, Anna; Erichsen, Louisa; Sorensen, Claus Storgaard; Pylkas, Katri; Winqvist, Robert; Peltoketo, Hellevi
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errSave
Self-inflicted DNA breaks in cell differentiation and cancer
errTRENDS IN CELL BIOLOGY
IF18.1
err2023-10-01
err3
errOAAI
errBenada, Jan; Alsowaida, Dalal; Megeney, Lynn A.; Sorensen, Claus S.
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errSave
ADAM12 expression is upregulated in cancer cells upon radiation and constitutes a prognostic factor in rectal cancer patients following radiotherapy
errCANCER GENE THERAPY
IF5
err2023-07-26
err3
errOAAI
errPiotrowski, Krzysztof Bartlomiej; Blasco, Laia Puig; Samsoe-Petersen, Jacob; Eefsen, Rikke Lovendahl; Illemann, Martin; Oria, Victor Oginga; Campos, Karla Iveth Aguilera; Lopresti, Alexia Melanie; Albrechtsen, Reidar; Sorensen, Claus Storgaard; Sun, Xiao-Feng; Kveiborg, Marie; Gnosa, Sebastian
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errSave
Synthetic lethal interaction between WEE1 and PKMYT1 is a target for multiple low-dose treatment of high-grade serous ovarian carcinoma
errNAR CANCER
IF3.2
err2023-06-13
err12
errOAAI
errBenada, Jan; Bulanova, Daria; Azzoni, Violette; Petrosius, Valdemaras; Ghazanfar, Saba; Wennerberg, Krister; Sorensen, Claus Storgaard
errShare
errSave
Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells
errNATURE METABOLISM
IF20.8
err2023-04-03
err11
errOAAI
errGreen, Alanna C.; Marttila, Petra; Kiweler, Nicole; Chalkiadaki, Christina; Wiita, Elisee; Cookson, Victoria; Lesur, Antoine; Eiden, Kim; Bernardin, Francois; Vallin, Karl S. A.; Borhade, Sanjay; Long, Maeve; Ghahe, Elahe Kamali; Jimenez-Alonso, Julio J.; Jemth, Ann-Sofie; Loseva, Olga; Mortusewicz, Oliver; Meyers, Marianne; Viry, Elodie; Johansson, Annika I.; Hodek, Ondrej; Homan, Evert; Bonagas, Nadilly; Ramos, Louise; Sandberg, Lars; Frodin, Morten; Moussay, Etienne; Slipicevic, Ana; Letellier, Elisabeth; Paggetti, Jerome; Sorensen, Claus Storgaard; Helleday, Thomas; Henriksson, Martin; Meiser, Johannes
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Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err99
errOAAI
errSorensen, CS; Lukas, C; Kramer, ER; Peters, JM; Bartek, J; Lukas, J
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errSave
Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err511
errOAAI
errSyljuåsen, RG; Sorensen, CS; Hansen, LT; Fugger, K; Lundin, C; Johansson, F; Helleday, T; Sehested, M; Lukas, J; Bartek, J
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errSave
A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and Cyclin A-Cdk2 during cell cycle progression
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err137
errOAAI
errSorensen, CS; Lukas, C; Kramer, ER; Peters, JM; Bartek, J; Lukas, J
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errSave
Cyclin-Dependent Kinase Suppression by WEE1 Kinase Protects the Genome through Control of Replication Initiation and Nucleotide Consumption
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err268
errOAAI
errBeck, Halfdan; Nahse-Kumpf, Viola; Larsen, Marie Sofie Yoo; O'Hanlon, Karen A.; Patzke, Sebastian; Holmberg, Christian; Mejlvang, Jakob; Groth, Anja; Nielsen, Olaf; Syljuasen, Randi G.; Sorensen, Claus Storgaard
errShare
errSave
DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation
errNATURE COMMUNICATIONS
IF15.7
err2023-01-26
err20
errOAAI
errKwon, Youngho; Rosner, Heike; Zhao, Weixing; Selemenakis, Platon; He, Zhuoling; Kawale, Ajinkya S.; Katz, Jeffrey N.; Rogers, Cody M.; Neal, Francisco E.; Shabestari, Aida Badamchi; Petrosius, Valdemaras; Singh, Akhilesh K.; Joel, Marina Z.; Lu, Lucy; Holloway, Stephen P.; Burma, Sandeep; Mukherjee, Bipasha; Hromas, Robert; Mazin, Alexander; Wiese, Claudia; Sorensen, Claus S.; Sung, Patrick
errShare
errSave
Multiparametric and accurate functional analysis of genetic sequence variants using CRISPR-Select
errNATURE GENETICS
IF31.8
err2022-12-05
err11
errOAAI
errNiu, Yiyuan; Azevedo, Catarina A. Ferreira A.; Li, Xin; Kamali, Elahe; Nielsen, Ole Haagen; Sorensen, Claus Storgaard; Frodin, Morten
errShare
errSave
Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1α and the NAMPT-NAD+ pathway
errNUCLEIC ACIDS RESEARCH
IF13.1
err2022-09-13
err20
errOAAI
errMaynard, Scott; Hall, Arnaldur; Galanos, Panagiotis; Rizza, Salvatore; Yamamoto, Tatsuro; Gram, Helena Hagner; Munk, Sebastian H. N.; Shoaib, Muhammad; Sorensen, Claus Storgaard; Bohr, Vilhelm A.; Lerdrup, Mads; Maya-Mendoza, Apolinar; Bartek, Jiri
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Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability (vol 19, 37, 2018)
errGENOME BIOLOGY
IF9.4
err2022-04-28
err2
errOAAI
errGalanos, Panagiotis; Pappas, George; Polyzos, Alexander; Kotsinas, Athanassios; Svolaki, Ioanna; Giakoumakis, Nickolaos N.; Glytsou, Christina; Pateras, Ioannis S.; Swain, Umakanta; Souliotis, Vassilis L.; Georgakilas, Alexandros G.; Geacintov, Nicholas; Scorrano, Luca; Lukas, Claudia; Lukas, Jiri; Livneh, Zvi; Lygerou, Zoi; Chowdhury, Dipanjan; Sorensen, Claus Storgaard; Bartek, Jiri; Gorgoulis, Vassilis G.
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Research Directions

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Co-authors
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