Jay T. Groves - Publications, H-index & Citations

Back

Jay T. Groves

University of California

69H-index

376Paper Count

1.6WCitation Count

Published Papers 205

Publication Date

Disordered protein LAT encodes relative levels of signaling pathways in T cell activation

Science

IF45.8

2026-04-30

PREAI

Adam J. Rubin; Tyler T. Dao; Amelia V. Schueppert; Saehyun Choi; Jay T. Groves; Aviv Regev; Alex K. Shalek

Save

Single-molecule biophysics in signaling: Functionality from stochastic effects

Current Opinion in Cell Biology

IF4.3

2025-11-08

OAAI

Jay T. Groves

Save

Autophosphorylation of oncoprotein TEL-ABL in myeloid and lymphoid cells confers resistance to the allosteric ABL inhibitor asciminib

Science Signaling

IF6.6

2025-07-15

PREAI

Serena Muratcioglu; Christopher A. Eide; Chien-Lun Hung; Kent Gorday; Emily Sumpena; Wenqi Zuo; Jay T. Groves; Brian J. Druker; John Kuriyan

Save

Bacterial XopR subverts RIN4 complex-mediated plant immunity via plasma membrane-associated percolation

Developmental Cell

IF8.7

2025-03-25

PREAI

Xinlu Zhu; Weibing Wang; Simou Sun; Choon-Peng Chng; Yi Xie; Kexin Zhu; Danxia He; Qiyu Liang; Zhiming Ma; Xi Wu; Xuanang Zheng; Weibo Gao; Ali Miserez; Caiji Gao; Jing Yu; Changjin Huang; Jay T. Groves; Yansong Miao

Save

Direct imaging with multidimensional labelling and high-content analysis allows quantitative categorization and characterizations of individual small extracellular vesicles and nanoparticles (sEVPs)

JOURNAL OF EXTRACELLULAR VESICLES

IF14.5

2024-12-12

OAAI

Sun, Simou; Cox-Vazquez, Sarah J.; Cho, Nam-Joon; Bazan, Guillermo C.; Groves, Jay T.

Save

Positive feedback in Ras activation by full-length SOS arises from autoinhibition release mechanism

BIOPHYSICAL JOURNAL

IF3.1

2024-10-01

OAAI

Ren, He; Lee, Albert A.; Lew, L. J. Nugent; Degrandchamp, Joseph B.; Groves, Jay T.

Save

Differential roles of kinetic on- and off- rates in T- cell receptor signal integration revealed with a modified Fab'- DNA ligand

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-09-19

OAAI

Wilhelm, Kiera B.; Vissa, Anand; Groves, Jay T.

Save

Bimodality in Ras signaling originates from processivity of the Ras activator SOS without deterministic bistability

SCIENCE ADVANCES

IF12.5

2024-06-21

OAAI

Lee, Albert A.; Kim, Neil H.; Alvarez, Steven; Ren, He; DeGrandchamp, Joseph B.; Lew, L. J. Nugent; Groves, Jay T.

Save

Allosteric inhibition of the T cell receptor by a designed membrane ligand

ELIFE

IF0

2023-10-05

OAAI

Ye, Yujie; Morita, Shumpei; Chang, Justin J.; Buckley, Patrick M.; Wilhelm, Kiera B.; DiMaio, Daniel; Groves, Jay T.; Barrera, Francisco N.

Save

Stimulation of the catalytic activity of the tyrosine kinase Btk by the adaptor protein Grb2

ELIFE

IF0

2023-04-26

OAAI

Nocka, Laura M.; Eisen, Timothy J.; Iavarone, Anthony T.; Groves, Jay T.; Kuriyan, John; Murphy, James M.

Save

A Membrane-Associated Light-Harvesting Model is Enabled by Functionalized Assemblies of Gene-Doubled TMV Proteins

SMALL

IF12.1

2023-02-21

OAAI

Dai, Jing; Wilhelm, Kiera B.; Bischoff, Amanda J.; Pereira, Jose H.; Dedeo, Michel T.; Garcia-Almedina, Derek M.; Adams, Paul D.; Groves, Jay T.; Francis, Matthew B.

Save

Discrete LAT condensates encode antigen information from single pMHC:TCR binding events

NATURE COMMUNICATIONS

IF15.7

2022-12-02

OAAI

McAffee, Darren B.; O'Dair, Mark K.; Lin, Jenny J.; Low-Nam, Shalini T.; Wilhelm, Kiera B.; Kim, Sungi; Morita, Shumpei; Groves, Jay T.

Save

Kinetic frustration by limited bond availability controls the LAT protein condensation phase transition on membranes

SCIENCE ADVANCES

IF12.5

2022-11-04

OAAI

Sun, Simou; GrandPre, Trevor; Limmer, David T.; Groves, Jay T.

Save

Membrane-mediated dimerization potentiates PIP5K lipid kinase activity

ELIFE

IF0

2022-08-17

OAAI

Hansen, Scott D.; Lee, Albert A.; Duewell, Benjamin R.; Groves, Jay T.

Save

A two-component protein condensate of the EGFR cytoplasmic tail and Grb2 regulates Ras activation by SOS at the membrane

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-05-04

OAAI

Lin, Chun-Wei; Nocka, Laura M.; Stinger, Brittany L.; DeGrandchamp, Joseph B.; Lew, L. J. Nugent; Alvarez, Steven; Phan, Henry T.; Kondo, Yasushi; Kuriyan, John; Groves, Jay T.

Save

Competition for shared downstream signaling molecules establishes indirect negative feedback between EGFR and EphA2

BIOPHYSICAL JOURNAL

IF3.1

2022-05-01

OAAI

Oh, Dongmyung; Chen, Zhongwen; Biswas, Kabir H.; Bai, Funing; Ong, Hui Ting; Sheetz, Michael P.; Groves, Jay T.

Save

Stochasticity and positive feedback enable enzyme kinetics at the membrane to sense reaction size

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-11-17

OAAI

Lee, Albert A.; Huang, William Y. C.; Hansen, Scott D.; Kim, Neil H.; Alvarez, Steven; Groves, Jay T.

Save

Relating cellular signaling timescales to single-molecule kinetics: A first-passage time analysis of Ras activation by SOS

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-11-05

OAAI

Huang, William Y. C.; Alvarez, Steven; Kondo, Yasushi; Kuriyan, John; Groves, Jay T.

Save

Height, but not binding epitope, affects the potency of synthetic TCR agonists (vol 120, pg 3869, 2021)

BIOPHYSICAL JOURNAL

IF3.1

2021-11-01

OAAI

Wilhelm, Kiera B.; Morita, Shumpei; McAffee, Darren B.; Kim, Sungi; O'Dair, Mark K.; Groves, Jay T.

Save

Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems

COMMUNICATIONS BIOLOGY

IF5.1

2021-09-09

OAAI

Laursen, Tomas; Lam, Hiu Yue Monatrice; Sorensen, Kasper Kildegaard; Tian, Pengfei; Hansen, Cecilie Cetti; Groves, Jay T.; Jensen, Knud Jorgen; Christensen, Sune M.

Save

Research Directions