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Brian Druker

Oregon Health & Science University

135H-index
2.6KPaper Count
9.6WCitation Count
Published Papers 189
Publication Date
The aryl hydrocarbon receptor is associated with monocytic AML and innate immune resistance reversible with an AHR inhibitor
err2025-12-09
err0
errOAAI
errJennifer N. Saultz; Daniel Bottomly; Faith Burns; Kaelan Byrd; Yoko Kosaka; Bernhard Alber; Daniel Chandra; Stephen E. Kurtz; Guang Fan; Andy Kaempf; Nicola Long; Marta Sanchez-Martin; Lei Wang; Karen McGovern; Dan S. Kaufman; Shannon K. McWeeney; Brian J. Druker; Jeffrey W. Tyner; Evan F. Lind
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Autophosphorylation of oncoprotein TEL-ABL in myeloid and lymphoid cells confers resistance to the allosteric ABL inhibitor asciminib
err2025-07-15
err0
PREAI
errSerena Muratcioglu; Christopher A. Eide; Chien-Lun Hung; Kent Gorday; Emily Sumpena; Wenqi Zuo; Jay T. Groves; Brian J. Druker; John Kuriyan
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Molecular characterization of newly diagnosed acute myeloid leukemia patients aged 60 years or older: a report from the Beat AML clinical trial
err2025-04-03
err0
errOAAI
errHoff, Fieke W.; Huang, Ying; Welkie, Rina Li; Swords, Ronan T.; Traer, Elie; Stein, Eytan M.; Lin, Tara L.; Patel, Prapti A.; Collins Jr, Robert H.; Baer, Maria R.; Duong, Vu H.; Blum, William G.; Arellano, Martha L.; Stock, Wendy; Odenike, Olatoyosi; Redner, Robert L.; Kovacsovics, Tibor; Deininger, Michael W.; Zeidner, Joshua F.; Olin, Rebecca L.; Smith, Catherine C.; Foran, James M.; Schiller, Gary J.; Curran, Emily K.; Koenig, Kristin L.; Heerema, Nyla A.; Chen, Timothy; Martycz, Molly; Stefanos, Mona; Marcus, Sonja G.; Rosenberg, Leonard; Druker, Brian J.; Levine, Ross L.; Burd, Amy; Yocum, Ashley O.; Borate, Uma M.; Mims, Alice S.; Byrd, John C.; Madanat, Yazan F.
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IDH2 Mutation Is Associated with Favorable Outcome Among Older Adults with Newly Diagnosed Acute Myeloid Leukemia Treated with Lower-Intensity Therapy
errBLOOD
IF23.1
err2024-11-05
err1
PREAI
errHoff, Fieke W.; Huang, Ying; Li Welkie, Rina; Swords, Ronan T.; Traer, Elie; Stein, Eytan M.; Lin, Tara L.; Patel, Prapti A.; Collins, Robert H.; Baer, Maria R.; Duong, Vu H.; Blum, William; Arellano, Martha L.; Stock, Wendy; Odenike, Olatoyosi; Redner, Robert L.; Kovacsovics, Tibor J.; Deininger, Michael W.; Zeidner, Joshua F.; Olin, Rebecca; Smith, Catherine C.; Foran, James M.; Schiller, Gary J.; Curran, Emily K.; Koenig, Kristin L.; Heerema, Nyla A.; Chen, Timothy; Martycz, Molly; Stefanos, Mona; Marcus, Sonja Gullen; Rosenberg, Leonard; Druker, Brian J.; Levine, Ross L.; Burd, Amy; Yocum, Ashley Owen; Borate, Uma; Mims, Alice; Byrd, John C.; Madanat, Yazan F.
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A Randomized Phase 2 Trial of 28-Day (Arm A) Versus 14-Day (Arm B) Schedule of Venetoclax plus Azacitidine in Newly Diagnosed Acute Myeloid Leukemia Patients ≥ 60 Years
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errBorate, Uma; Huang, Ying; Zeidner, Joshua F.; Swords, Ronan T.; Koenig, Kristin L.; Stein, Eytan M.; Baer, Maria R.; Stock, Wendy; Madanat, Yazan F.; Olin, Rebecca; Blum, William; Schiller, Gary J.; Lin, Tara L.; Curran, Emily K.; Martycz, Molly; Rosenberg, Leonard; Marcus, Sonja Gullen; Chen, Timothy; Stefanos, Mona; Levine, Ross L.; Druker, Brian J.; Yocum, Ashley Owen; Burd, Amy; Mims, Alice; Byrd, John C.
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Beat-AML 2024 ELN-refined risk stratification for older adults with newly diagnosed AML given lower-intensity therapy
err2024-10-10
err2
errOAAI
errHoff, Fieke W.; Blum, William G.; Huang, Ying; Li Welkie, Rina; Swords, Ronan T.; Traer, Elie; Stein, Eytan M.; Lin, Tara L.; Archer, Kellie J.; Patel, Prapti A.; Collins, Robert H.; Baer, Maria R.; Duong, Vu H.; Arellano, Martha L.; Stock, Wendy; Odenike, Olatoyosi; Redner, Robert L.; Kovacsovics, Tibor; Deininger, Michael W.; Zeidner, Joshua F.; Olin, Rebecca L.; Smith, Catherine C.; Foran, James M.; Schiller, Gary J.; Curran, Emily K.; Koenig, Kristin L.; Heerema, Nyla A.; Chen, Timothy; Martycz, Molly; Stefanos, Mona; Marcus, Sonja G.; Rosenberg, Leonard; Druker, Brian J.; Levine, Ross L.; Burd, Amy; Yocum, Ashley O.; Borate, Uma M.; Mims, Alice S.; Byrd, John C.; Madanat, Yazan F.
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Mass Spectrometry-Based Proteogenomics: New Therapeutic Opportunities for Precision Medicine
err2024-01-23
err6
errOAAI
errJoshi, Sunil K.; Piehowski, Paul; Liu, Tao; Gosline, Sara J. C.; McDermott, Jason E.; Druker, Brian J.; Traer, Elie; Tyner, Jeffrey W.; Agarwal, Anupriya; Tognon, Cristina E.; Rodland, Karin D.
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A study to assess the efficacy of enasidenib and risk-adapted addition of azacitidine in newly diagnosed IDH2-mutant AML
err2024-01-12
err7
errOAAI
errCai, Sheng F.; Huang, Ying; Lance, Jennie R.; Mao, Hsiaoyin Charlene; Dunbar, Andrew J.; McNulty, Samantha N.; Druley, Todd; Li, Yan; Baer, Maria R.; Stock, Wendy; Kovacsovics, Tibor; Blum, William G.; Schiller, Gary J.; Olin, Rebecca L.; Foran, James M.; Litzow, Mark; Lin, Tara; Patel, Prapti; Foster, Matthew C.; Boyiadzis, Michael; Collins, Robert H.; Chervin, Jordan; Shoben, Abigail; Vergilio, Jo-Anne; Heerema, Nyla A.; Rosenberg, Leonard; Chen, Timothy L.; Yocum, Ashley O.; Druggan, Franchesca; Marcus, Sonja; Stefanos, Mona; Druker, Brian J.; Mims, Alice S.; Borate, Uma; Burd, Amy; Byrd, John C.; Levine, Ross L.; Stein, Eytan M.
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Mapping the proteogenomic landscape enables prediction of drug response in acute leukemia
err2024-01-01
err3
errOAAI
errPino, James C.; Posso, Camilo; Joshi, Sunil K.; Nestor, Michael; Moon, Jamie; Hansen, Joshua R.; Hutchinson-Bunch, Chelsea; Gritsenko, Marina A.; Weitz, Karl K.; Watanabe-Smith, Kevin; Long, Nicola; Mcdermott, Jason E.; Druker, Brian J.; Liu, Tao; Tyner, Jeffrey W.; Agarwal, Anupriya; Traer, Elie; Piehowski, Paul D.; Tognon, Cristina E.; Rodland, Karin D.; Gosline, Sara J. C.
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Samples from patients with AML show high concordance in detection of mutations by NGS at local institutions vs central laboratories
err2023-10-11
err1
errOAAI
errBorate, Uma; Yang, Fei; Press, Richard; Ruppert, Amy S.; Jones, Dan; Caruthers, Sean; Zhao, Weiqiang; Vergilio, Jo-Anne; Pavlick, Dean C.; Juckett, Luke; Norris, Brianna; Bucy, Taylor; Burd, Amy; Stein, Eytan M.; Patel, Prapti; Baer, Maria R.; Stock, Wendy; Schiller, Gary; Blum, William; Kovacsovics, Tibor; Litzow, Mark; Foran, James; Heerema, Nyla A.; Rosenberg, Leonard; Marcus, Sonja; Yocum, Ashley; Stefanos, Mona; Druker, Brian; Byrd, John C.; Levine, Ross L.; Mims, Alice
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The FLT3N701K mutation causes clinical AML resistance to gilteritinib and triggers TKI sensitivity switch to quizartinib
err2023-10-10
err2
errOAAI
errJoshi, Sunil K.; Pittsenbarger, Janet; Kennedy, Vanessa E.; Peretz, Cheryl A. C.; Perl, Alexander E.; Smith, Catherine C.; Tyner, Jeffrey W.; Druker, Brian J.; Traer, Elie
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Clinical Correlates of Venetoclax-Based Combination Sensitivities to Augment Acute Myeloid Leukemia Therapy
err2023-09-11
err8
PREAI
errEide, Christopher A.; Kurtz, Stephen E.; Kaempf, Andy; Long, Nicola; Joshi, Sunil Kumar; Nechiporuk, Tamilla; Huang, Ariane; Dibb, Charles A.; Taylor, Akosha; Bottomly, Daniel; Mcweeney, Shannon K.; Minnier, Jessica; Lachowiez, Curtis A.; Saultz, Jennifer N.; Swords, Ronan T.; Agarwal, Anupriya; Chang, Bill H.; Druker, Brian J.; Tyner, Jeffrey W.
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Risk of progression in chronic phase-chronic myeloid leukemia patients eligible for tyrosine kinase inhibitor discontinuation: Final analysis of the TFR-PRO study
err2023-08-30
err3
errOAAI
errZambrotta, Giovanni Paolo Maria; Nicolini, Franck E.; Assouline, Sarit; Busque, Lambert; Pungolino, Ester; Abruzzese, Elisabetta; Miggiano, Maria Cristina; Elena, Chiara; Alvarez-Larran, Alberto; Triguero, Ana; Iurlo, Alessandra; Bucelli, Cristina; Cerrano, Marco; Capodanno, Isabella; Lunghi, Francesca; le Coutre, Philipp; Galimberti, Sara; Caocci, Giovanni; Maffioli, Margherita; Stagno, Fabio; Saussele, Susanne; Piazza, Rocco; Druker, Brian J.; Fava, Carmen; Guglielmana, Veronica; Colombo, Federica; Antolini, Laura; Gambacorti-Passerini, Carlo
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Pevonedistat with azacitidine in older patients with TP53-mutated AML: a phase 2 study with laboratory correlates
err2023-05-25
err8
errOAAI
errSaliba, Antoine N.; Kaufmann, Scott H.; Stein, Eytan M.; Patel, Prapti A.; Baer, Maria R.; Stock, Wendy; Deininger, Michael; Blum, William; Schiller, Gary J.; Olin, Rebecca L.; Litzow, Mark R.; Lin, Tara L.; Ball, Brian J.; Boyiadzis, Michael M.; Traer, Elie; Odenike, Olatoyosi; Arellano, Martha L.; Walker, Alison; Duong, Vu H.; Kovacsovics, Tibor; Collins, Robert H.; Shoben, Abigail B.; Heerema, Nyla A.; Foster, Matthew C.; Peterson, Kevin L.; Schneider, Paula A.; Martycz, Molly; Gana, Theophilus J.; Rosenberg, Leonard; Marcus, Sonja; Yocum, Ashley O.; Chen, Timothy; Stefanos, Mona; Mims, Alice S.; Borate, Uma; Burd, Amy; Druker, Brian J.; Levine, Ross L.; Byrd, John C.; Foran, James M.
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Comparison and validation of the 2022 European LeukemiaNet guidelines in acute myeloid leukemia
err2023-05-09
err35
errOAAI
errLachowiez, Curtis A.; Long, Nicola; Saultz, Jennifer; Gandhi, Arpita; Newell, Laura F.; Hayes-Lattin, Brandon; Maziarz, Richard T.; Leonard, Jessica; Bottomly, Daniel; McWeeney, Shannon; Dunlap, Jennifer; Press, Richard; Meyers, Gabrielle; Swords, Ronan; Cook, Rachel J.; Tyner, Jeffrey W.; Druker, Brian J.; Traer, Elie
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ASO-mediated NRAS knockdown overcomes gilteritinib late resistance in FLT3-AML
err2023-05-01
err0
PREAI
errJoshi, Sunil K.; Pittsenbarger, Janet; Luo, Xiaolin; Maazi, Hadi; Revenko, Alexey; Druker, Brian J.; Traer, Elie
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Entospletinib with decitabine in acute myeloid leukemia with mutant TP53 or complex karyotype: A phase 2 substudy of the Beat AML Master Trial
errCANCER
IF5.1
err2023-04-20
err7
PREAI
errDuong, Vu H.; Ruppert, Amy S.; Mims, Alice S.; Borate, Uma; Stein, Eytan M.; Baer, Maria R.; Stock, Wendy; Kovacsovics, Tibor; Blum, William; Arellano, Martha L.; Schiller, Gary J.; Olin, Rebecca L.; Foran, James M.; Litzow, Mark R.; Lin, Tara L.; Patel, Prapti A.; Foster, Matthew C.; Redner, Robert L.; Al-Mansour, Zeina; Cogle, Christopher R.; Swords, Ronan T.; Collins, Robert H.; Vergilio, Jo-Anne; Heerema, Nyla A.; Rosenberg, Leonard; Yocum, Ashley O.; Marcus, Sonja; Chen, Timothy; Druggan, Franchesca; Stefanos, Mona; Gana, Theophilus J.; Shoben, Abigail B.; Druker, Brian J.; Burd, Amy; Byrd, John C.; Levine, Ross L.; Boyiadzis, Michael M.
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Mapping the molecular landscape of acute myeloid leukemia enables prediction of drug response from proteogenomic data
err2023-04-04
err0
PREAI
errPino, James C.; Posso, Camilo; Joshi, Sunil K.; Nestor, Michael; Moon, Jamie; Hansen, Joshua R.; Gritsenko, Marina A.; Hutchinson-Bunch, Chelsea; Weitz, Karl K.; Watanabe-Smith, Kevin; McDermott, Jason E.; Druker, Brian J.; Liu, Tao; Tyner, Jeffrey W.; Agarwal, Anupriya; Traer, Elie; Piehowski, Paul D.; Tognon, Cristina E.; Rodland, Karin D.; Gosline, Sara J.
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