Janne Tynell - Publications, H-index & Citations

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Janne Tynell

finland national institute for health & welfare

18H-index

30Paper Count

3.1KCitation Count

Published Papers 13

Publication Date

Comprehensive proteomics and meta-analysis of COVID-19 host response

NATURE COMMUNICATIONS

IF15.7

2023-09-22

OAAI

Babacic, Haris; Christ, Wanda; Araujo, Jose Eduardo; Mermelekas, Georgios; Sharma, Nidhi; Tynell, Janne; Garcia, Marina; Varnaite, Renata; Asgeirsson, Hilmir; Glans, Hedvig; Lehtioe, Janne; Gredmark-Russ, Sara; Klingstroem, Jonas; Pernemalm, Maria

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Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2023-06-14

PREAI

Mittler, Eva; Serris, Alexandra; Esterman, Emma S.; Florez, Catalina; Polanco, Laura C.; O'Brien, Cecilia M.; Slough, Megan M.; Tynell, Janne; Groning, Remigius; Sun, Yan; Abelson, Dafna M.; Wec, Anna Z.; Haslwanter, Denise; Keller, Markus; Ye, Chunyan; Bakken, Russel R.; Jangra, Rohit K.; Dye, John M.; Ahlm, Clas; Rappazzo, C. Garrett; Ulrich, Rainer G.; Zeitlin, Larry; Geoghegan, James C.; Bradfute, Steven B.; Sidoli, Simone; Forsell, Mattias N. E.; Strandin, Tomas; Rey, Felix A.; Herber, Andrew S.; Walker, Laura M.; Chandran, Kartik; Guardado-Calvo, Pablo

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Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2022-03-16

OAAI

Mittler, Eva; Wec, Anna Z.; Tynell, Janne; Guardado-Calvo, Pablo; Wigren-Bystrom, Julia; Polanco, Laura C.; O'Brien, Cecilia M.; Slough, Megan M.; Abelson, Dafna M.; Serris, Alexandra; Sakharkar, Mrunal; Pehau-Arnaudet, Gerard; Bakken, Russell R.; Geoghegan, James C.; Jangra, Rohit K.; Keller, Markus; Zeitlin, Larry; Vapalahti, Olli; Ulrich, Rainer G.; Bornholdt, Zachary A.; Ahlm, Clas; Rey, Felix A.; Dye, John M.; Bradfute, Steven B.; Strandin, Tomas; Herbert, Andrew S.; Forsell, Mattias N. E.; Walker, Laura M.; Chandran, Kartik

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Expansion of SARS-CoV-2-Specific Antibody-Secreting Cells and Generation of Neutralizing Antibodies in Hospitalized COVID-19 Patients

JOURNAL OF IMMUNOLOGY

IF3.4

2020-11-01

OAAI

Varnaite, Renata; Garcia, Marina; Glans, Hedvig; Maleki, Kimia T.; Sandberg, John Tyler; Tynell, Janne; Christ, Wanda; Lagerqvist, Nina; Asgeirsson, Hilmir; Ljunggren, Hans-Gustaf; Ahlen, Gustaf; Frelin, Lars; Sallberg, Matti; Blom, Kim; Klingstrom, Jonas; Gredmark-Russ, Sara

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Puumala and Andes Orthohantaviruses Cause Transient Protein Kinase R-Dependent Formation of Stress Granules

JOURNAL OF VIROLOGY

IF3.8

2020-01-17

OAAI

Christ, Wanda; Tynell, Janne; Klingstrom, Jonas

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Regulation of kynurenine biosynthesis during influenza virus infection

FEBS JOURNAL

IF4.2

2016-12-14

OAAI

Gaelings, Lana; Soderholm, Sandra; Bugai, Andrii; Fu, Yu; Nandania, Jatin; Schepens, Bert; Lorey, Martina B.; Tynell, Janne; Vande Ginste, Liesbeth; Le Goffic, Ronan; Miller, Matthew S.; Kuisma, Marika; Marjomaki, Varpu; De Brabander, Jef; Matikainen, Sampsa; Nyman, Tuula A.; Bamford, Dennis H.; Saelens, Xavier; Julkunen, Ilkka; Paavilainen, Henrik; Hukkanen, Veijo; Velagapudi, Vidya; Kainov, Denis E.

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Middle East respiratory syndrome coronavirus shows poor replication but significant induction of antiviral responses in human monocyte-derived macrophages and dendritic cells

JOURNAL OF GENERAL VIROLOGY

IF4.3

2016-02-01

OAAI

Tynell, Janne; Westenius, Veera; Ronkko, Esa; Munster, Vincent J.; Melen, Krister; Osterlund, Pamela; Julkunen, Ilkka

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Middle East respiratory syndrome coronavirus (MERS-CoV) shows poor replication and weak induction of antiviral responses in human monocyte-derived macrophages and dendritic cells

JOURNAL OF CLINICAL VIROLOGY

IF3.4

2015-09-01

OAAI

Tynell, J.; Westenius, V.; Ronkko, E.; Munster, V. J.; Melen, K.; Osterlund, P.; Julkunen, I.

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Mutations within the conserved NS1 nuclear export signal lead to inhibition of influenza A virus replication

VIROLOGY JOURNAL

IF3.8

2014-07-14

OAAI

Tynell, Janne; Melen, Krister; Julkunen, Ilkka

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Akt Inhibitor MK2206 Prevents Influenza pH1N1 Virus Infection In Vitro

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2014-07-01

OAAI

Denisova, Oxana V.; Soderholm, Sandra; Virtanen, Salla; Von Schantz, Carina; Bychkov, Dmitrii; Vashchinkina, Elena; Desloovere, Jens; Tynell, Janne; Ikonen, Niina; Theisen, Linda L.; Nyman, Tuula A.; Matikainen, Sampsa; Kallioniemi, Olli; Julkunen, Ilkka; Muller, Claude P.; Saelens, Xavier; Verkhusha, Vladislav V.; Kainov, Denis E.

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Anticancer compound ABT-263 accelerates apoptosis in virus-infected cells and imbalances cytokine production and lowers survival rates of infected mice

CELL DEATH & DISEASE

IF9.6

2013-07-25

OAAI

Kakkola, L.; Denisova, O. V.; Tynell, J.; Viiliainen, J.; Ysenbaert, T.; Matos, R. C.; Nagaraj, A.; Ohman, T.; Kuivanen, S.; Paavilainen, H.; Feng, L.; Yadav, B.; Julkunen, I.; Vapalahti, O.; Hukkanen, V.; Stenman, J.; Aittokallio, T.; Verschuren, E. W.; Ojala, P. M.; Nyman, T.; Saelens, X.; Dzeyk, K.; Kainov, D. E.

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Obatoclax, Saliphenylhalamide, and Gemcitabine Inhibit Influenza A Virus Infection

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2012-10-01

OAAI

Denisova, Oxana V.; Kakkola, Laura; Feng, Lin; Stenman, Jakob; Nagaraj, Ashwini; Lampe, Johanna; Yadav, Bhagwan; Aittokallio, Tero; Kaukinen, Pasi; Ahola, Tero; Kuivanen, Suvi; Vapalahti, Olli; Kantele, Anu; Tynell, Janne; Julkunen, Ilkka; Kallio-Kokko, Hannimari; Paavilainen, Henrik; Hukkanen, Veijo; Elliott, Richard M.; De Brabander, Jef K.; Saelens, Xavier; Kainov, Denis E.

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Influenza A H3N2 subtype virus NS1 protein targets into the nucleus and binds primarily via its C-terminal NLS2/NoLS to nucleolin and fibrillarin

VIROLOGY JOURNAL

IF3.8

2012-08-21

OAAI

Melen, Krister; Tynell, Janne; Fagerlund, Riku; Roussel, Pascal; Hernandez-Verdun, Daniele; Julkunen, Ilkka

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Research Directions