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Chinten James Lim

University of British Columbia

31H-index
134Paper Count
3.7KCitation Count
Published Papers 46
Publication Date
Proteomics and personalized PDX models identify treatment for a progressive malignancy within an actionable timeframe
err2025-04-01
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errBarnabas, Georgina D.; Bhat, Tariq A.; Goebeler, Verena; Leclair, Pascal; Azzam, Nadine; Melong, Nicole; Anderson, Colleen; Gom, Alexis; An, Seohee; Ergin, Enes K.; Shen, Yaoqing; Conrrero, Agustina; Mungall, Andrew J.; Mungall, Karen L.; Maxwell, Christopher A.; Reid, Gregor S. D.; Hirst, Martin; Jones, Steven; Chan, Jennifer A.; Senger, Donna L.; Berman, Jason N.; Parker, Seth J.; Bush, Jonathan W.; Strahlendorf, Caron; Deyell, Rebecca J.; Lim, C. James; Lange, Philipp F.
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High-Dimensional Single-Cell Analysis of Clinical-Grade Flow Cytometry Explains the Unpredictable Complex Shifts of Patient-Specific Immunophenotypes during B-ALL Relapse Progression
errBLOOD
IF23.1
err2024-11-05
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PREAI
errRolf, Nina; Liu, Lorraine Y. T.; Leclair, Pascal; Atre, Tanmaya; Vercauteren, Suzanne; Lim, Chinten James; Reid, Gregor S. D.
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Canada's path towards proteome guided therapies and advanced molecular pathology in pediatric precision oncology
err2024-09-05
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PREAI
errBarnabas, Georgina; Bhat, Tariq; Goebeler, V.; Leclair, P.; Maxwell, C.; Reid, G.; Senger, D. L.; Chan, J. A.; Azzam, N.; Melong, N.; Berman, J. N.; Parker, S.; Bush, J.; Strahlendorf, C.; Deyell, R.; Lim, C. J.; Lange, Philipp F.
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Prioritizing treatment targets for an adolescent with metastatic processive malignancy using proteomics and personalized xenograft models within an actionable timeframe
err2024-03-22
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PREAI
errBarnabas, Georgina D.; Bhat, Tariq A.; Goebeler, Verena; Leclair, Pascal; Azzam, Nadine; Melong, Nicole; Berman, Jason N.; Chan, Jennifer A.; Senger, Donna L.; Parker, Seth; Maxwell, Christopher A.; Reid, Gregor S.; Bush, Jonathan; Strahlendorf, Caron; Deyell, Rebecca; Lim, C. James; Lange, Philipp F.
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DDIT4L regulates mitochondrial and innate immune activities in early life
err2024-02-06
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errMichalski, Christina; Cheung, Claire; Oh, Ju Hee; Ackermann, Emma; Popescu, Constantin R.; Archambault, Anne -Sophie; Prusinkiewicz, Martin A.; Silva, Rachel Da; Majdoubi, Abdelilah; Paramo, Marina Vineta; Xu, Rui Yang; Reicherz, Frederic; Patterson, Annette E.; Golding, Liam; Sharma, Ashish A.; Lim, Chinten J.; Orban, Paul C.; Geltink, Ramon I. Klein; Lavoie, Pascal M.
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Targetable lesions and proteomes predict therapy sensitivity through disease evolution in pediatric acute lymphoblastic leukemia
err2023-11-21
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errLorentzian, Amanda C.; Rever, Jenna; Ergin, Enes K.; Guo, Meiyun; Akella, Neha M.; Rolf, Nina; Lim, C. James; Reid, Gregor S. D.; Maxwell, Christopher A.; Lange, Philipp F.
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Protein Tyrosine Phosphatase α Phosphotyrosyl-789 Binds BCAR3 To Position Cas for Activation at Integrin-Mediated Focal Adhesions
err2023-03-20
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errSun, Guobin; Cheng, Suzanne Y. S.; Chen, Min; Lim, Chinten James; Pallen, Catherine J.
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The Membrane-Proximal KXGFFKR Motif of α-Integrin Mediates Chemoresistance
err2023-03-20
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errOAAI
errLiu, Chi-Chao; Leclair, Pascal; Yap, Shyong Quin; Lim, Chinten James
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Hedgehog Signaling as a Therapeutic Target for Airway Remodeling and Inflammation in Allergic Asthma
errCELLS
IF5.2
err2022-09-27
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errOAAI
errTam, Anthony; Osei, Emmanuel Twumasi; Cheung, Chung Y.; Hughes, Michael; Yang, Chen X.; McNagny, Kelly M.; Dorscheid, Delbert R.; Singhera, Gurpreet K.; Hallstrand, Teal S.; Warner, Stephanie; Hogg, James C.; Hackett, Tillie L.; Lim, Chinten J.; Sin, Don D.
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Lipid nanoparticle formulations for optimal RNA-based topical delivery to murine airways
err2022-09-01
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errTam, A.; Kulkarni, J.; An, K.; Li, L.; Dorscheid, D. R.; Singhera, G. K.; Bernatchez, P.; Reid, G. S. D.; Chan, K. Y. T.; Witzigmann, D.; Cullis, P. R.; Sin, D. D.; Lim, C. J.
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Inflammatory Immune Responses Trigger Rejection of Allogeneic Fibroblasts Transplanted into Mouse Skin
err2022-07-30
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errOAAI
errFarrokhi, Ali; Rahavi, MohammadReza; Jo, Sumin; Jalili, Reza; Lim, C. James; Ghahsary, Aziz; Reid, Gregor S. D.
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Targeting the gp130/STAT3 Axis Attenuates Tumor Microenvironment Mediated Chemoresistance in Group 3 Medulloblastoma Cells
errCELLS
IF5.2
err2022-01-23
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errOAAI
errSreenivasan, Lakshana; Li, Ling Vicky; Leclair, Pascal; Lim, Chinten James
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HIV-1 Vpu Promotes Phagocytosis of Infected CD4+ T Cells by Macrophages through Downregulation of CD47
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IF4.7
err2021-08-31
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errOAAI
errCong, Lijun; Sugden, Scott M.; Leclair, Pascal; Lim, Chinten James; Pham, Tram N. Q.; Cohen, Eric A.
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FAM13A as potential therapeutic target in modulating TGF-β-induced airway tissue remodeling in COPD
err2021-08-01
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errTam, Anthony; Leclair, Pascal; Li, Ling Vicky; Yang, Chen X.; Li, Xuan; Witzigmann, Dominik; Kulkarni, Jayesh A.; Hackett, Tillie-Louise; Dorscheid, Delbert R.; Singhera, Gurpreet K.; Hogg, James C.; Cullis, Pieter R.; Sin, Don D.; Lim, Chinten James
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Receptor-type protein tyrosine phosphatase alpha (PTPα) mediates MMP14 localization and facilitates triple-negative breast cancer cell invasion
err2021-04-01
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errOAAI
errDecotret, Lisa R.; Wadsworth, Brennan J.; Li, Ling Vicky; Lim, Chinten J.; Bennewith, Kevin L.; Pallen, Catherine J.
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PDX models reflect the proteome landscape of pediatric acute lymphoblastic leukemia but divert in select pathways
err2021-03-15
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errUzozie, Anuli C.; Ergin, Enes K.; Rolf, Nina; Tsui, Janice; Lorentzian, Amanda; Weng, Samuel S. H.; Nierves, Lorenz; Smith, Theodore G.; Lim, C. James; Maxwell, Christopher A.; Reid, Gregor S. D.; Lange, Philipp F.
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MicroRNA modification of coxsackievirus B3 decreases its toxicity, while retaining oncolytic potency against lung cancer (vol 16, pg 207, 2020)
err2021-03-01
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errOAAI
errLiu, Huitao; Xue, Yuan Chao; Deng, Haoyu; Mohamud, Yasir; Chen Seng Ng; Chu, Axel; Lim, Chinten James; Lockwood, William W.; Jia, William W. G.; Luo, Honglin
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Autocrine IL-6/STAT3 signaling aids development of acquired drug resistance in Group 3 medulloblastoma
err2020-12-05
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errSreenivasan, Lakshana; Wang, Hui; Yap, Shyong Quin; Leclair, Pascal; Tam, Anthony; Lim, Chinten James
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MicroRNA Modification of Coxsackievirus B3 Decreases Its Toxicity, while Retaining Oncolytic Potency against Lung Cancer
err2020-03-01
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errLiu, Huitao; Xue, Yuan Chao; Deng, Haoyu; Mohamud, Yasir; Ng, Chen Seng; Chu, Axel; Lim, Chinten James; Lockwood, William W.; Jia, William W. G.; Luo, Honglin
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