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Tom Moss

laval university

50H-index
184Paper Count
8.1KCitation Count
Published Papers 43
Publication Date
A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response
err2023-10-19
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errSubramanian, Advait; Wang, Lan; Moss, Tom; Voorhies, Mark; Sangwan, Smriti; Stevenson, Erica; Pulido, Ernst H.; Kwok, Samentha; Chalkley, Robert J.; Li, Kathy H.; Krogan, Nevan J.; Swaney, Danielle L.; Burlingame, Alma L.; Floor, Stephen N.; Sil, Anita; Walter, Peter; Mukherjee, Shaeri
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Transcription factor UBF depletion in mouse cells results in downregulation of both downstream and upstream elements of the rRNA transcription network
err2023-10-01
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errTheophanous, Andria; Christodoulou, Andri; Mattheou, Charalambia; Sibai, Dany S.; Moss, Tom; Santama, Niovi
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mTOR-Dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF
err2023-03-27
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errHannan, KM; Brandenburger, Y; Jenkins, A; Sharkey, K; Cavanaugh, A; Rothblum, L; Moss, T; Poortinga, G; McArthur, GA; Pearson, RB; Hannan, RD
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Control of ribosomal RNA synthesis by hematopoietic transcription factors br
err2022-10-01
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errAntony, Charles; George, Subin S.; Blum, Justin; Somers, Patrick; Thorsheim, Chelsea L.; Wu-Corts, Dexter J.; Ali, Yuxi; Gao, Long; Lv, Kaosheng; Tremblay, Michel G.; Moss, Tom; Tan, Kai; Wilusz, Jeremy E.; Ganley, Austen R. D.; Pimkin, Maxim; Paralkar, Vikram R.
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The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans
err2022-09-01
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errDaiss, Julia L.; Pilsl, Michael; Straub, Kristina; Bleckmann, Andrea; Hoecherl, Mona; Heiss, Florian B.; Abascal-Palacios, Guillermo; Ramsay, Ewan P.; Tluckova, Katarina; Mars, Jean-Clement; Fuertges, Torben; Bruckmann, Astrid; Rudack, Till; Bernecky, Carrie; Lamour, Valerie; Panov, Konstantin; Vannini, Alessandro; Moss, Tom; Engel, Christoph
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Ribosomal DNA promoter recognition is determined in vivo by cooperation between UBTF1 and SL1 and is compromised in the UBTF-E210K neuroregression syndrome
err2022-02-09
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errTremblay, Michel G.; Sibai, Dany S.; Valere, Melissa; Mars, Jean-Clement; Lessard, Frederic; Hori, Roderick T.; Khan, Mohammad Moshahid; Stefanovsky, Victor Y.; LeDoux, Mark S.; Moss, Tom
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The chemotherapeutic agent CX-5461 irreversibly blocks RNA polymerase I initiation and promoter release to cause nucleolar disruption, DNA damage and cell inviability
err2020-11-06
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errMars, Jean-Clement; Tremblay, Michel G.; Valere, Melissa; Sibai, Dany S.; Sabourin-Felix, Marianne; Lessard, Frederic; Moss, Tom
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A recurrent de novo missense mutation in UBTF causes developmental neuroregression (vol 27, pg 691, 2018)
err2018-02-13
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errToro, Camilo; Hori, Roderick T.; Malicdan, May Christine V.; Tifft, Cynthia J.; Goldstein, Amy; Gahl, William A.; Adams, David R.; Fauni, Harper B.; Wolfe, Lynne A.; Xiao, Jianfeng; Khan, Mohammad M.; Tian, Jun; Hope, Kevin A.; Reiter, Lawrence T.; Tremblay, Michel G.; Moss, Tom; Franks, Alexis L.; Balak, Chris; LeDoux, Mark S.
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A recurrent de novo missense mutation in UBTF causes developmental neuroregression
err2018-01-02
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errToro, Camilo; Hori, Roderick T.; Malicdan, May Christine V.; Tifft, Cynthia J.; Goldstein, Amy; Gahl, William A.; Adams, David R.; Harper, Fauni; Wolfe, Lynne A.; Xiao, Jianfeng; Khan, Mohammad M.; Tian, Jun; Hope, Kevin A.; Reiter, Lawrence T.; Tremblay, Michel G.; Moss, Tom; Franks, Alexis L.; Balak, Chris; LeDoux, Mark S.
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A unique enhancer boundary complex on the mouse ribosomal RNA genes persists after loss of Rrn3 or UBF and the inactivation of RNA polymerase I transcription
err2017-07-17
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errHerdman, Chelsea; Mars, Jean-Clement; Stefanovsky, Victor Y.; Tremblay, Michel G.; Sabourin-Felix, Marianne; Lindsay, Helen; Robinson, Mark D.; Moss, Tom
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Extended synaptotagmin interaction with the fibroblast growth factor receptor depends on receptor conformation, not catalytic activity (vol 290, pg 16142, 2015)
err2016-02-01
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errTremblay, Michel G.; Herdman, Chelsea; Guillou, Francois; Mishra, Prakash K.; Baril, Joelle; Bellenfant, Sabrina; Moss, Tom
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Extended Synaptotagmin Interaction with the Fibroblast Growth Factor Receptor Depends on Receptor Conformation, Not Catalytic Activity
err2015-06-01
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errTremblay, Michel G.; Herdman, Chelsea; Guillou, Francois; Mishra, Prakash K.; Baril, Joelle; Bellenfant, Sabrina; Moss, Tom
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A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes
err2014-12-01
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errSanij, Elaine; Diesch, Jeannine; Lesmana, Analia; Poortinga, Gretchen; Hein, Nadine; Lidgerwood, Grace; Cameron, Donald P.; Ellul, Jason; Goodall, Gregory J.; Wong, Lee H.; Dhillon, Amardeep S.; Hamdane, Nourdine; Rothblum, Lawrence I.; Pearson, Richard B.; Haviv, Izhak; Moss, Tom; Hannan, Ross D.
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Mice lacking both mixed-lineage kinase genes Mlk1 and Mlk2 retain a wild type phenotype
err2014-10-29
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errBisson, Nicolas; Tremblay, Michel; Robinson, Fiona; Kaplan, David R.; Trusko, Steven P.; Moss, Tom
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Conditional Inactivation of Upstream Binding Factor Reveals Its Epigenetic Functions and the Existence of a Somatic Nucleolar Precursor Body
err2014-08-14
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errHamdane, Nourdine; Stefanovsky, Victor Y.; Tremblay, Michel G.; Nemeth, Attila; Paquet, Eric; Lessard, Frederic; Sanij, Elaine; Hannan, Ross; Moss, Tom
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