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Pradeep Rajasekhar

The Walter and Eliza Hall Institute of Medical Research

15H-index
63Paper Count
988Citation Count
Published Papers 22
Publication Date
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A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease
errScience
IF45.8
err2026-08-27
err0
PREAI
errJiyi Pang; Aysha H. Al-Ani; Komal M. Patel; Yunzhuo Zhou; Samuel N. Young; Jinjin Chen; Isabella Kong; Marilou Barrios; James A. Rickard; Siqi Chen; Xiuquan Ma; Farzaneh Shojaee; Seong-Beom Kim; Siavash Foroughi; Wayne Cawthorne; Annette V. Jacobsen; Asha Jois; Ashley L. Weir; Lachlan W. Whitehead; Pradeep Rajasekhar; Christopher R. Horne; Ruqian Lyu; Lucy J. Mather; Raymond K. H. Yip; Ellen Tsui; Imadh Azeez; Tao Tan; Weiwei Liang; Suresh Sivanesan; Andrew Metz; Ash Patwardhan; Natalie Shea; Guru Iyngkaran; Daniel Schneider; Alexander T. Elford; William Beattie; Finlay Macrae; Gianmaria Liccardi; Henning Walczak; Yuxia Zhang; Oliver M. Sieber; Tim Spelman; Lisa Giulino-Roth; Michael Christie; Yunshun Chen; Kelly L. Rogers; Rory Bowden; Sandra E. Nicholson; Kate E. Lawlor; Edwin D. Hawkins; Britt Christensen; Andre L. Samson; James E. Vince; James M. Murphy
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Non-apoptotic caspase-8 is critical for orchestrating exaggerated inflammation during severe SARS-CoV-2 infection
errNature Communications
IF15.7
err2025-11-13
err0
errOAAI
errStefanie M. Bader; Lena Scherer; Reet Bhandari; Allan J. Motyer; James P. Cooney; Liana Mackiewicz; Merle Dayton; Dylan Sheerin; David V. L. Romero; Jan Schaefer; Jiyi Pang; Siqi Chen; Kael Schoffer; Le Wang; Xinyi Jin; Daniel Batey; Raymond K. H. Yip; Ishrat Zaman; Pradeep Rajasekhar; Matthew J. Gartner; Stephen Wilcox; Lachlan Whitehead; Smitha Rose Georgy; Ana Maluenda; Kathryn C. Davidson; Cody C. Allison; Rory Bowden; Kerstin Brinkmann; Marie-Liesse Asselin-Labat; Belinda Phipson; Maria C. Tanzer; Marco J. Herold; Andre L. Samson; James E. Vince; Andreas Strasser; Marc Pellegrini; Marcel Doerflinger
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The formation of the ‘footprint of death’ as a mechanism for generating large substrate-bound extracellular vesicles that mark the site of cell death
errNature Communications
IF15.7
err2025-10-15
err0
errOAAI
errStephanie F. Rutter; Taeyoung Kang; Gemma F. Ryan; Bo Shi; Caitlin L. Vella; Pradeep Rajasekhar; Sean W. Cutter; Amy L. Hodge; Dilara C. Ozkocak; Ching-Seng Ang; Julian Ratcliffe; Katrina J. Binger; Pamali Foneska; Suresh Mathivanan; Niall D. Geoghegan; Kelly L. Rogers; Michael F. Olson; Georgia K. Atkin-Smith; Ivan K. H. Poon
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Author Correction: In situ visualization of endothelial cell-derived extracellular vesicle formation in steady state and malignant conditions
errNature Communications
IF15.7
err2025-10-03
err0
errOAAI
errGeorgia K. Atkin-Smith; Jascinta P. Santavanond; Amanda Light; Joel S. Rimes; Andre L. Samson; Jeremy Er; Joy Liu; Darryl N. Johnson; Mélanie Le Page; Pradeep Rajasekhar; Raymond K. H. Yip; Niall D. Geoghegan; Kelly L. Rogers; Catherine Chang; Vanessa L. Bryant; Mai Margetts; M. Cristina Keightley; Trevor J. Kilpatrick; Michele D. Binder; Sharon Tran; Erinna F. Lee; Walter D. Fairlie; Dilara C. Ozkocak; Andrew H. Wei; Edwin D. Hawkins; Ivan K. H. Poon
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Benchmarking spatial transcriptomics technologies with the multi-sample SpatialBenchVisium dataset
errGENOME BIOLOGY
IF9.4
err2025-03-28
err1
errOAAI
errDu, Mei R. M.; Wang, Changqing; Law, Charity W.; Amann-Zalcenstein, Daniela; Anttila, Casey J. A.; Ling, Ling; Hickey, Peter F.; Sargeant, Callum J.; Chen, Yunshun; Ioannidis, Lisa J.; Rajasekhar, Pradeep; Yip, Raymond K. H.; Rogers, Kelly L.; Hansen, Diana S.; Bowden, Rory; Ritchie, Matthew E.
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KAT6B overexpression in mice causes aggression, anxiety, and epilepsy
errISCIENCE
IF4.1
err2025-03-01
err0
errOAAI
errBergamasco, Maria I.; Ozturk, Ezgi; Casillas-Espinosa, Pablo M.; Garnham, Alexandra L.; Abeysekera, Waruni; Wimmer, Verena C.; Rajasekhar, Pradeep; Vanyai, Hannah K.; Whitehead, Lachlan; Blewitt, Marnie E.; Rogers, Kelly; Vogel, Adam P.; Hannan, Anthony J.; Smyth, Gordon K.; Jones, Nigel C.; Thomas, Tim; Voss, Anne K.
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errSave
A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease
errJOURNAL OF CROHNS & COLITIS
IF8.7
err2025-01-22
err0
PREAI
errAl-Ani, A.; Pang, J.; Patel, K.; Young, S. N.; Kong, I; Chen, J. J.; Barrios, M.; Rickard, J.; Chen, S.; Foroughi, S.; Cawthorne, W.; Jacobsen, A.; Jois, A.; Weir, A.; Whitehead, L.; Rajasekhar, P.; Horne, C.; Azeez, I; Zhang, Y.; Sieber, O.; Spelman, T.; Giulino-Roth, L.; Hawkins, E.; Rogers, K.; Bowden, R.; Nicholson, S.; Lawlor, K.; Samson, A. L.; Vince, J. E.; Murphy, J. M.; Christensen, B.
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errSave
In situ visualization of endothelial cell-derived extracellular vesicle formation in steady state and malignant conditions
errNATURE COMMUNICATIONS
IF15.7
err2024-10-22
err0
errOAAI
errAtkin-Smith, Georgia K.; Santavanond, Jascinta P.; Light, Amanda; Rimes, Joel S.; Samson, Andre L.; Er, Jeremy; Liu, Joy; Johnson, Darryl N.; Le Page, Melanie; Rajasekhar, Pradeep; Yip, Raymond K. H.; Geoghegan, Niall D.; Rogers, Kelly L.; Chang, Catherine; Bryant, Vanessa L.; Margetts, Mai; Keightley, M. Cristina; Kilpatrick, Trevor J.; Binder, Michele D.; Tran, Sharon; Lee, Erinna F.; Fairlie, Walter D.; Ozkocak, Dilara C.; Wei, Andrew H.; Hawkins, Edwin D.; Poon, Ivan K. H.
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errSave
An immunohistochemical atlas of necroptotic pathway expression
errEMBO MOLECULAR MEDICINE
IF8.3
err2024-05-15
err6
errOAAI
errChiou, Shene; Al-Ani, Aysha H.; Pan, Yi; Patel, Komal M.; Kong, Isabella Y.; Whitehead, Lachlan W.; Light, Amanda; Young, Samuel N.; Barrios, Marilou; Sargeant, Callum; Rajasekhar, Pradeep; Zhu, Leah; Hempel, Anne; Lin, Ann; Rickard, James A.; Hall, Cathrine; Gangatirkar, Pradnya; Yip, Raymond K. H.; Cawthorne, Wayne; Jacobsen, Annette, V; Horne, Christopher R.; Martin, Katherine R.; Ioannidis, Lisa J.; Hansen, Diana S.; Day, Jessica; Wicks, Ian P.; Law, Charity; Ritchie, Matthew E.; Bowden, Rory; Hildebrand, Joanne M.; O'Reilly, Lorraine A.; Silke, John; Giulino-Roth, Lisa; Tsui, Ellen; Rogers, Kelly L.; Hawkins, Edwin D.; Christensen, Britt; Murphy, James M.; Samson, Andre L.
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Stroke Alters the Function of Enteric Neurons to Impair Smooth Muscle Relaxation and Dysregulates Gut Transit
errJOURNAL OF THE AMERICAN HEART ASSOCIATION
IF5.3
err2024-02-06
err3
errOAAI
errKumar, Kathryn Prame; Wilson, Jenny L.; Nguyen, Huynh; McKay, Liam D.; Wen, Shu Wen; Sepehrizadeh, Tara; de Veer, Michael; Rajasekhar, Pradeep; Carbone, Simona E.; Hickey, Michael J.; Poole, Daniel P.; Wong, Connie H. Y.
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errSave
Identification of aberrant luminal progenitors and mTORC1 as a potential breast cancer prevention target in BRCA2 mutation carriers
errNATURE CELL BIOLOGY
IF19.1
err2024-01-12
err8
PREAI
errJoyce, Rachel; Pascual, Rosa; Heitink, Luuk; Capaldo, Bianca D.; Vaillant, Francois; Christie, Michael; Tsai, Minhsuang; Surgenor, Elliot; Anttila, Casey J. A.; Rajasekhar, Pradeep; Jackling, Felicity C.; Trussart, Marie; Milevskiy, Michael J. G.; Song, Xiaoyu; Li, Mengbo; Teh, Charis E.; Gray, Daniel H. D.; Smyth, Gordon K.; Chen, Yunshun; Lindeman, Geoffrey J.; Visvader, Jane E.
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Serotonin-induced vascular permeability is mediated by transient receptor potential vanilloid 4 in the airways and upper gastrointestinal tract of mice
errLABORATORY INVESTIGATION
IF4.2
err2021-07-01
err11
errOAAI
errRetamal, Jeffri S.; Grace, Megan S.; Dill, Larissa K.; Ramirez-Garcia, Paulina; Peng, Scott; Gondin, Arisbel B.; Bennetts, Felix; Alvi, Sadia; Rajasekhar, Pradeep; Almazi, Juhura G.; Carbone, Simona E.; Bunnett, Nigel W.; Davis, Thomas P.; Veldhuis, Nicholas A.; Poole, Daniel P.; McIntyre, Peter
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Enteric Glia Modulate Macrophage Phenotype and Visceral Sensitivity following Inflammation
errCELL REPORTS
IF6.9
err2020-09-01
err110
errOAAI
errGrubisic, Vladimir; McClain, Jonathon L.; Fried, David E.; Grants, Iveta; Rajasekhar, Pradeep; Csizmadia, Eva; Ajijola, Olujimi A.; Watson, Ralph E.; Poole, Daniel P.; Robson, Simon C.; Christofi, Fievos L.; Gulbransen, Brian D.
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Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2020-06-16
err73
errOAAI
errJimenez-Vargas, Nestor N.; Gong, Jing; Wisdom, Matthew J.; Jensen, Dane D.; Latorre, Rocco; Hegron, Alan; Teng, Shavonne; DiCello, Jesse J.; Rajasekhar, Pradeep; Veldhuis, Nicholas A.; Carbone, Simona E.; Yu, Yang; Lopez-Lopez, Cintya; Jaramillo-Polanco, Josue; Canals, Meritxell; Reed, David E.; Lomax, Alan E.; Schmidt, Brian L.; Leong, Kam W.; Vanner, Stephen J.; Halls, Michelle L.; Bunnett, Nigel W.; Poole, Daniel P.
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Mu and Delta Opioid Receptors Are Coexpressed and Functionally Interact in the Enteric Nervous System of the Mouse Colon
errCELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
IF7.4
err2020-01-01
err22
errOAAI
errDiCello, Jesse J.; Carbone, Simona E.; Saito, Ayame; Rajasekhar, Pradeep; Ceredig, Rhian A.; Pham, Vi; Valant, Celine; Christopoulos, Arthur; Veldhuis, Nicholas A.; Canals, Meritxell; Massotte, Dominique; Poole, Daniel P.
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Clathrin and GRK2/3 inhibitors block δ-opioid receptor internalization in myenteric neurons and inhibit neuromuscular transmission in the mouse colon
errAMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
IF3.3
err2019-08-01
err9
errOAAI
errDiCello, Jesse T.; Rajasekhar, Pradeep; Eriksson, Emily M.; Saito, Ayame; Gondin, Arisbel B.; Veldhuis, Nicholas A.; Canals, Meritxell; Carbone, Simona E.; Poole, Daniel P.
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errSave
Agonist-dependent development of delta opioid receptor tolerance in the colon
errCELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
err2019-03-23
err7
PREAI
errDiCello, Jesse J.; Saito, Ayame; Rajasekhar, Pradeep; Sebastian, Benjamin W.; McQuade, Rachel M.; Gondin, Arisbel B.; Veldhuis, Nicholas A.; Canals, Meritxell; Carbone, Simona E.; Poole, Daniel P.
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Inflammation-associated changes in DOR expression and function in the mouse colon
errAMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
IF3.3
err2018-10-01
err22
errOAAI
errDiCello, Jesse J.; Saito, Ayame; Rajasekhar, Pradeep; Eriksson, Emily M.; McQuade, Rachel M.; Nowell, Cameron J.; Sebastian, Benjamin W.; Fichna, Jakub; Veldhuis, Nicholas A.; Canals, Meritxell; Bunnett, Nigel W.; Carbone, Simona E.; Poole, Daniel P.
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errSave
G-CSF Receptor Blockade Ameliorates Arthritic Pain and Disease
errJOURNAL OF IMMUNOLOGY
IF3.4
err2017-05-01
err31
errOAAI
errLee, Ming-Chin; McCubbin, James A.; Christensen, Anne D.; Poole, Daniel P.; Rajasekhar, Pradeep; Lieu, TinaMarie; Bunnett, Nigel W.; Garcia-Caraballo, Sonia; Erickson, Andelain; Brierley, Stuart M.; Saleh, Reem; Achuthan, Adrian; Fleetwood, Andrew J.; Anderson, Robin L.; Hamilton, John A.; Cook, Andrew D.
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P2Y1 Receptor Activation of the TRPV4 Ion Channel Enhances Purinergic Signaling in Satellite Glial Cells
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2015-11-01
err42
errOAAI
errRajasekhar, Pradeep; Poole, Daniel P.; Liedtke, Wolfgang; Bunnett, Nigel W.; Veldhuis, Nicholas A.
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
A
Andreas Strasser
H-index: 135 · Papers: 815
K
Kam W. Leong
H-index: 131 · Papers: 853
T
Thomas P. Davis
H-index: 116 · Papers: 856
G
Gordon K. Smyth
H-index: 113 · Papers: 595
S
Simon C. Robson
H-index: 100 · Papers: 722
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