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J

Julien Dilly

dana-farber cancer institute

10H-index
231Paper Count
907Citation Count
Published Papers 15
Publication Date
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Acquired resistance to the RAS(ON) multi-selective inhibitor daraxonrasib guides rational combination therapy strategies in pancreatic cancer
errNature Medicine
IF50
err2026-08-11
err0
errOAAI
errIda Aronchik; Sumit Kar; Yongxian Zhuang; Ethan Ahler; Lick Pui Lai; Vidya Seshadri; Yu Chi Yang; Ashenafi Bulle; Marie Menard; Biswadeep Nayak; Mark P. Labrecque; Julien Dilly; Eejung Kim; Lingyan Jiang; Jason Yano; Urszula N. Wasko; Ciara Helland; Sean Bredeson; Brett Garrick; Yevgeniy Gindin; Brad Sickler; Xing Wei; Kyle Seamon; Jingjing Jiang; Kian-Huat Lim; Matthew Holderfield; Elsa Quintana; Aparna Hegde; Zeena Salman; Alexander Starodub; Alexander Spira; Wungki Park; David S. Hong; Minal Barve; Meredith Pelster; David Sommerhalder; Salman R. Punekar; Ignacio Garrido-Laguna; Brian M. Wolpin; Anirban Maitra; W. Clay Gustafson; Steve Kelsey; Jacqueline A. M. Smith; Kevin K. Lin; Andrew J. Aguirre; Mallika Singh
errShare
errSave
A dependency map enhanced with next-generation 3D cancer models
errNature
IF48.5
err2026-08-05
err0
errOAAI
errJames V. Neiswender; Samuel Maffa; Lisa Brenan; Dina ElHarouni; Yejie Yun; Isabella Boyle; Kirsty Wienand; Haider Inam; Tate Bertea; Ashley Anderson; Megan Wong; Matias Enriquez; Evan Lenz; Beatriz Villafranca; Nora Shanks; Mary Hager; Nia Lloyd; Hannah Shadmany; Sarah J. Wie; Harry Liang; Konnor Yunghans; Xiaomeng Zhang; Lauren Golden; Hannah Harris; Serena Day; Philip Montgomery; Samantha Stokes; Ross M. Giglio; Cynthia Hajal; James R. Whittle; Guadalupe Garcia; Caitlin E. Mills; Mehdi Touat; Kristine Pelton; Hongyu Li; Prem Sai Prabhakar; Sonja Herter; Zoe Hoffmann Kamrat; Dan Gui; Julien Dilly; Chen Khuan Wong; Jimmy A. Guo; Sangita Pal; Yossef Baidi; Ryan Johnston; Daniel D. Brown; Sonam Bhatia; Peter S. Winter; Srivatsan Raghavan; Rameen Beroukhim; Eva Colas; David L. Spector; Adam J. Bass; Peter K. Sorger; Yu Chen; Sarah J. Hill; Steffi Oesterreich; Adrian V. Lee; Himisha Beltran; Jesse S. Boehm; Yuen-Yi Tseng; David E. Root; William C. Hahn; Andrew J. Aguirre; Catarina D. Campbell; Keith L. Ligon; Joshua M. Dempster; Tsukasa Shibue; Francisca Vazquez
errShare
errSave
Integrative genomic identification of therapeutic targets for pancreatic cancer
errCell Reports
IF6.9
err2025-08-21
err0
PREAI
errJimmy A. Guo; Dennis Gong; Kyle Evans; Kazuki Takahashi; Ananya D. Jambhale; Carina Shiau; Patrick Yu; Steven Wang; Wenbo W. Wu; Seema Chugh; Kevin S. Kapner; Julien Dilly; Daniel Zhao; Peter Chen; Eric L. Smith; Joseph D. Mancias; Francisca Vazquez; Harshabad Singh; William L. Hwang; Andrew J. Aguirre
errShare
errSave
A neomorphic protein interface catalyzes covalent inhibition of RASG12D aspartic acid in tumors
errScience
IF45.8
err2025-07-24
err0
PREAI
errCaroline Weller; G. Leslie Burnett; Lingyan Jiang; Sujata Chakraborty; Dongyu Zhang; Nicole A. Vita; Julien Dilly; Eejung Kim; Benjamin Maldonato; Kyle Seamon; Diane F. Eilerts; Anthony Milin; Abby Marquez; Jessica Spradlin; Ciara Helland; Andrea Gould; Tamar Bar Ziv; Phuong Dinh; Shelby L. Steele; Zhican Wang; Yunming Mu; Seema Chugh; Hanrong Feng; Conner Hennessey; Junning Wang; Jennifer Roth; Matthew Rees; Melissa Ronan; Brian M. Wolpin; William C. Hahn; Matthew Holderfield; Zhengping Wang; Elena S. Koltun; Mallika Singh; Adrian L. Gill; Jacqueline A. M. Smith; Andrew J. Aguirre; Jingjing Jiang; John E. Knox; David Wildes
errShare
errSave
Targeting KRAS inhibitor resistance by ferroptosis induction in PDAC
errCANCER RESEARCH
IF16.6
err2024-09-15
err0
PREAI
errPadhye, Aparna; Yu, Qijia; Sindoni, Nicole; Zhang, Huan; Dilly, Julien; Feng, Hanrong; Aguirre, Andrew; Mancias, Joseph
errShare
errSave
Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer
errCANCER DISCOVERY
IF33.3
err2024-07-05
err7
PREAI
errDilly, Julien; Hoffman, Megan T.; Abbassi, Laleh; Li, Ziyue; Paradiso, Francesca; Parent, Brendan D.; Hennessey, Connor J.; Jordan, Alexander C.; Morgado, Micaela; Dasgupta, Shatavisha; Uribe, Giselle A.; Yang, Annan; Kapner, Kevin S.; Hambitzer, Felix P.; Qiang, Li; Feng, Hanrong; Geisberg, Jacob; Wang, Junning; Evans, Kyle E.; Lyu, Hengyu; Schalck, Aislyn; Feng, Ningping; Lopez, Anastasia M.; Bristow, Christopher A.; Kim, Michael P.; Rajapakshe, Kimal I.; Bahrambeigi, Vahid; Roth, Jennifer A.; Garg, Kavita; Guerrero, Paola A.; Stanger, Ben Z.; Cristea, Simona; Lowe, Scott W.; Baslan, Timour; Van Allen, Eliezer M.; Mancias, Joseph D.; Chan, Emily; Anderson, Abraham; Katlinskaya, Yuliya V.; Shalek, Alex K.; Hong, David S.; Pant, Shubham; Hallin, Jill; Anderes, Kenna; Olson, Peter; Heffernan, Timothy P.; Chugh, Seema; Christensen, James G.; Maitra, Anirban; Wolpin, Brian M.; Raghavan, Srivatsan; Nowak, Jonathan A.; Winter, Peter S.; Dougan, Stephanie K.; Aguirre, Andrew J.
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errSave
Resistance to RAS-GTP inhibition in models of pancreatic ductal adenocarcinoma arises downstream of RAS effectors
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errWasko, Urszula N.; Jiang, Jingjing; Wang, Yingyun; Tomassoni, Lorenzo; Jiang, Lingyan; Menard, Marie; Curiel-Garcia, Alvaro; Dalton, Tanner C.; Orlen, Margo; Edwards, Cole; Stalnecker, Clint; Dilly, Julien; Chang, Stephanie; Sastra, Stephen A.; Palermo, Carmine F.; Baslan, Timour; Tian, Sha; Holderfield, Matthew; Quintana, Elsa; Wang, Zhengping; Smith, Jacqueline A.; Califano, Andrea; Wildes, David; Aguirre, Andrew J.; Vonderheide, Robert H.; Stanger, Ben Z.; Lowe, Scott W.; Der, Channing J.; Singh, Mallika; Olive, Kenneth P.
errShare
errSave
Dissecting acquired resistance to KRASG12D inhibition in a mouse model of pancreatic ductal adenocarcinoma
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errDilly, Julien; Abbassi, Laleh; Hennessey, Connor J.; Uribe, Giselle A.; Parent, Brendan; Yang, Annan; Kapner, Kevin S.; Li, Ziyue; Evans, Kyle E.; Dasgupta, Shatavisha; Hoffman, Megan T.; Qiang, Li; Hambitzer, Felix P.; Chugh, Seema; Shalek, Alex K.; Dougan, Stephanie K.; Wolpin, Brian M.; Nowak, Jonathan A.; Raghavan, Srivatsan; Winter, Peter S.; Aguirre, Andrew J.
errShare
errSave
Deciphering acquired resistance to KRASG12D inhibition in a mouse model of pancreatic ductal adenocarcinoma
errCANCER RESEARCH
IF16.6
err2024-01-16
err0
PREAI
errDilly, Julien; Abbassi, Laleh; Hennessey, Connor J.; Uribe, Giselle A.; Parent, Brendan; Yang, Annan; Kapner, Kevin S.; Li, Ziyue; Dasgupta, Shatavisha; Jordan, Alexander; Hoffman, Megan T.; Qiang, Li; Hambitzer, Felix P.; Chugh, Seema; Shalek, Alex K.; Dougan, Stephanie K.; Wolpin, Brian M.; Nowak, Jonathan A.; Raghavan, Srivatsan; Winter, Peter S.; Aguirre, Andrew J.
errShare
errSave
Tumor-selective inhibition of active RAS in pancreatic ductal adenocarcinoma
errCANCER RESEARCH
IF16.6
err2024-01-16
err0
PREAI
errWasko, Urszula N.; Jiang, Jingjing; Tomassoni, Lorenzo; Wang, Yingyun; Lee, Bianca; Orlen, Margo; Drizyte-Miller, Kristina; Menard, Marie; Dilly, Julien; Sastra, Steven A.; Palermo, Carmine F.; Chang, Stephanie; Aguirre, Andrew J.; Der, Channing J.; Vonderheide, Robert H.; Stanger, Ben Z.; Califano, Andrea; Singh, Mallika; Olive, Kenneth P.
errShare
errSave
RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling
errSCIENCE SIGNALING
IF6.6
err2023-12-19
err0
errOAAI
errSchaefer, Antje; Hodge, Richard G.; Zhang, Haisheng; Hobbs, G. Aaron; Dilly, Julien; Huynh, Minh V.; Goodwin, Craig M.; Zhang, Feifei; Diehl, J. Nathaniel; Pierobon, Mariaelena; Baldelli, Elisa; Javaid, Sehrish; Guthrie, Karson; Rashid, Naim U.; Petricoin, Emanuel F.; Cox, Adrienne D.; Hahn, William C.; Aguirre, Andrew J.; Bass, Adam J.; Der, Channing J.
errShare
errSave
Oncogenic Drivers and Therapeutic Vulnerabilities in KRAS Wild-Type Pancreatic Cancer
errCLINICAL CANCER RESEARCH
IF10.2
err2023-07-18
err21
errOAAI
errSingh, Harshabad; Keller, Rachel B.; Kapner, Kevin S.; Dilly, Julien; Raghavan, Srivatsan; Yuan, Chen; Cohen, Elizabeth F.; Tolstorukov, Michael; Andrews, Elizabeth; Brais, Lauren K.; da Silva, Annacarolina; Perez, Kimberly; Rubinson, Douglas A.; Surana, Rishi; Giannakis, Marios; Ng, Kimmie; Clancy, Thomas E.; Yurgelun, Matthew B.; Schlechter, Benjamin L.; Clark, Jeffrey W.; Shapiro, Geoffrey I.; Rosenthal, Michael H.; Hornick, Jason L.; Nardi, Valentina; Li, Yvonne Y.; Gupta, Hersh; Cherniack, Andrew D.; Meyerson, Matthew; Cleary, James M.; Nowak, Jonathan A.; Wolpin, Brian M.; Aguirre, Andrew J.
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errSave
The RAF/MEK clamp avutometinib (VS-6766) enhances antitumor efficacy of KRAS G12C and G12D inhibitors through vertical inhibition of RAS, RAF and MEK
errMOLECULAR CANCER RESEARCH
IF4.7
err2023-05-01
err1
PREAI
errComa, Silvia; Musteanu, Monica; Caffarra, Cristina; Mira, Alessia; Patrucco, Enrico; Dilly, Julien; Aguirre, Andrew J.; Barbacid, Mariano; Ambrogio, Chiara; Pachter, Jonathan A.
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errSave
GLIS3 drives a neural-like malignant state enriched after neoadjuvant treatment in pancreatic cancer
errCANCER RESEARCH
IF16.6
err2023-04-04
err1
PREAI
errGuo, Jimmy A.; Su, Jennifer; Shiau, Carina; Jambhale, Ananya; Yang, Annan; Wu, Westley; Wang, Junning; Hennessey, Connor; Yu, Patrick; Parent, Brendan; Uribe, Giselle; Dilly, Julien; Abbassi, Laleh; Yu, Qijia; Mehta, Arnav; Ting, David; Wolpin, Brian; Freed-Pastor, William; Mancias, Joseph; Jacks, Tyler; Hwang, William L.; Aguirre, Andrew J.
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errSave
Cyclic uniaxial mechanical stretching of cells using a LEGO® parts-based mechanical stretcher system
errJOURNAL OF CELL SCIENCE
IF3.6
err2020-01-06
err16
errOAAI
errBoulter, Etienne; Tissot, Floriane S.; Dilly, Julien; Pisano, Sabrina; Feral, Chloe C.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
M
Matthew Meyerson
H-index: 223 · Papers: 1.9K
T
Tyler Jacks
H-index: 158 · Papers: 817
S
Scott W. Lowe
H-index: 156 · Papers: 977
A
ArkingDan (Anirban Maitra)
H-index: 156 · Papers: 1.8K
R
Rameen Beroukhim
H-index: 149 · Papers: 899
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