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Therapeutic benefit of the dual ALK/FAK inhibitor ESK440 in ALK-driven neuroblastoma Chugh, Seema; Tien, Jean C.; Hon, Jennifer; Kenum, Carson; Mannan, Rahul; Cheng, Yunhui; Li, Chi Chiang; Taher, Zainab I.; Delekta, Andrew D.; Bawa, Pushpinder Singh; Apel, Ingrid J.; Miner, Stephanie J.; Cao, Xuhong; Mehra, Rohit; Dhanasekaran, Saravana M.; Qiao, Yuanyuan; Mody, Rajen; Chinnaiyan, Arul M. Share Save
Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer Dilly, Julien; Hoffman, Megan T.; Abbassi, Laleh; Li, Ziyue; Paradiso, Francesca; Parent, Brendan D.; Hennessey, Connor J.; Jordan, Alexander C.; Morgado, Micaela; Dasgupta, Shatavisha; Uribe, Giselle A.; Yang, Annan; Kapner, Kevin S.; Hambitzer, Felix P.; Qiang, Li; Feng, Hanrong; Geisberg, Jacob; Wang, Junning; Evans, Kyle E.; Lyu, Hengyu; Schalck, Aislyn; Feng, Ningping; Lopez, Anastasia M.; Bristow, Christopher A.; Kim, Michael P.; Rajapakshe, Kimal I.; Bahrambeigi, Vahid; Roth, Jennifer A.; Garg, Kavita; Guerrero, Paola A.; Stanger, Ben Z.; Cristea, Simona; Lowe, Scott W.; Baslan, Timour; Van Allen, Eliezer M.; Mancias, Joseph D.; Chan, Emily; Anderson, Abraham; Katlinskaya, Yuliya V.; Shalek, Alex K.; Hong, David S.; Pant, Shubham; Hallin, Jill; Anderes, Kenna; Olson, Peter; Heffernan, Timothy P.; Chugh, Seema; Christensen, James G.; Maitra, Anirban; Wolpin, Brian M.; Raghavan, Srivatsan; Nowak, Jonathan A.; Winter, Peter S.; Dougan, Stephanie K.; Aguirre, Andrew J. Share Save
Comprehensive proteogenomic characterization of rare kidney tumors Li, Ginny Xiaohe; Chen, Lijun; Hsiao, Yi; Mannan, Rahul; Zhang, Yuping; Luo, Jie; Petralia, Francesca; Cho, Hanbyul; Hosseini, Noshad; Leprevost, Felipe da Veiga; Calinawan, Anna; Li, Yize; Anand, Shankara; Dagar, Aniket; Geffen, Yifat; Kumar-Sinha, Chandan; Chugh, Seema; Le, Anne; Ponce, Sean; Guo, Shenghao; Zhang, Cissy; Schnaubelt, Michael; Deen, Nataly Naser Al; Chen, Feng; Caravan, Wagma; Houston, Andrew; Hopkins, Alex; Newton, Chelsea J.; Wang, Xiaoming; Polasky, Daniel A.; Haynes, Sarah; Yu, Fengchao; Jing, Xiaojun; Chen, Siqi; Robles, Ana I.; Mesri, Mehdi; Thiagarajan, Mathangi; An, Eunkyung; Getz, Gad A.; Linehan, W. Marston; Hostetter, Galen; Jewell, Scott D.; Chan, Daniel W.; Wang, Pei; Omenn, Gilbert S.; Mehra, Rohit; Ricketts, Christopher J.; Ding, Li; Chinnaiyan, Arul M.; Cieslik, Marcin P.; Dhanasekaran, Saravana M.; Zhang, Hui; Nesvizhskii, Alexey I. Share Save
Dissecting acquired resistance to KRASG12D inhibition in a mouse model of pancreatic ductal adenocarcinoma Dilly, Julien; Abbassi, Laleh; Hennessey, Connor J.; Uribe, Giselle A.; Parent, Brendan; Yang, Annan; Kapner, Kevin S.; Li, Ziyue; Evans, Kyle E.; Dasgupta, Shatavisha; Hoffman, Megan T.; Qiang, Li; Hambitzer, Felix P.; Chugh, Seema; Shalek, Alex K.; Dougan, Stephanie K.; Wolpin, Brian M.; Nowak, Jonathan A.; Raghavan, Srivatsan; Winter, Peter S.; Aguirre, Andrew J. Share Save
Deciphering acquired resistance to KRASG12D inhibition in a mouse model of pancreatic ductal adenocarcinoma Dilly, Julien; Abbassi, Laleh; Hennessey, Connor J.; Uribe, Giselle A.; Parent, Brendan; Yang, Annan; Kapner, Kevin S.; Li, Ziyue; Dasgupta, Shatavisha; Jordan, Alexander; Hoffman, Megan T.; Qiang, Li; Hambitzer, Felix P.; Chugh, Seema; Shalek, Alex K.; Dougan, Stephanie K.; Wolpin, Brian M.; Nowak, Jonathan A.; Raghavan, Srivatsan; Winter, Peter S.; Aguirre, Andrew J. Share Save
Response and resistance to KRAS inhibition in PDAC mouse models Abbassi, Laleh; Dilly, Jullien; Yang, Annan; Uribe, Giselle; Parent, Branden; Hennessey, Connor; Kapner, Kevin; Jordan, Alexander; Dasgupta, Shatavisha; Morgado, Micaela; Baslan, Taimour; Qiang, Li; Winter, Peter; Chugh, Seema; Shalek, Alex; Stanger, Ben; Raghavan, Srivastan; Lowe, Scott; Wolpin, Brian; Dougan, Stephanie; Nowak, Jonathan; Aguirre, Andrew Share Save
Molecular stratification of therapeutic targets in pancreatic cancer Gong, Dennis; Guo, Jimmy A.; Shiau, Carina; Jambhale, Ananya D.; Wang, Steven; Ginebaugh, Scott; Yu, Patrick Z.; Kapner, Kevin S.; Chugh, Seema; Abbassi, Laleh; Zhao, Daniel; Wu, Westley W.; Chen, Peter; Singh, Harshabad; Hwang, William L.; Aguirre, Andrew J. Share Save
Argonaute 2 modulates EGFR-RAS signaling to promote mutant HRAS and NRAS-driven malignancies Siebenaler, Ronald F.; Chugh, Seema; Waninger, Jessica J.; Dommeti, Vijaya L.; Kenum, Carson; Mody, Malay; Gautam, Anudeeta; Patel, Nidhi; Chu, Alec; Bawa, Pushpinder; Hon, Jennifer; Smith, Richard D.; Carlson, Heather; Cao, Xuhong; Tesmer, John J. G.; Shankar, Sunita; Chinnaiyan, Arul M. Share Save
Reduction in O-glycome induces differentially glycosylated CD44 to promote stemness and metastasis in pancreatic cancer Leon, Frank; Seshacharyulu, Parthasarathy; Nimmakayala, Rama K.; Chugh, Seema; Karmakar, Saswati; Nallasamy, Palanisamy; Vengoji, Raghupathy; Rachagani, Satyanarayana; Cox, Jesse L.; Mallya, Kavita; Batra, Surinder K.; Ponnusamy, Moorthy P. Share Save
AGO2 promotes tumor progression in KRAS-driven mouse models of non-small cell lung cancer Tien, Jean Ching-Yi; Chugh, Seema; Goodrum, Andrew E.; Cheng, Yunhui; Mannan, Rahul; Zhang, Yuping; Wang, Lisha; Dommeti, Vijaya L.; Wang, Xiaoming; Xu, Alice; Hon, Jennifer; Kenum, Carson; Su, Fengyun; Wang, Rui; Cao, Xuhong; Shankar, Sunita; Chinnaiyan, Arul M. Share Save
Metabolic programming of distinct cancer stem cells promotes metastasis of pancreatic ductal adenocarcinoma Nimmakayala, Rama Krishna; Leon, Frank; Rachagani, Satyanarayana; Rauth, Sanchita; Nallasamy, Palanisamy; Marimuthu, Saravanakumar; Shailendra, Gautam K.; Chhonker, Yashpal S.; Chugh, Seema; Chirravuri, Ramakanth; Gupta, Rohitesh; Mallya, Kavita; Prajapati, Dipakkumar R.; Lele, Subodh M.; C. Caffrey, Thomas; L. Grem, Jean; Grandgenett, Paul M.; Hollingsworth, Michael A.; Murry, Daryl J.; Batra, Surinder K.; Ponnusamy, Moorthy P. Share Save
An essential role for Argonaute 2 in HRAS and NRAS driven oncogenesis Siebenaler, Ronald F.; Waninger, Jessica; Shankar, Sunita; Chugh, Seema; Chu, Shih-Chun; Tien, Jean; Dommeti, Vijaya L.; Mody, Malay; Gautam, Anudeeta; Kenum, Carson; Kumar-Sinha, Chandan; Chinnaiyan, Arul M. Share Save
AGO2 interaction limits wild type RAS activation yet essential for disease progression in oncogenic KRAS driven cancers Shankar, Sunita; Tien, Jean Ching-Yi; Siebenaler, Ronald F.; Chugh, Seema; Dommeti, Vijaya L.; Zelenka-Wang, Sylvia; Waninger, Jessica; Juckette, Kristin M.; Wang, Xiao-Ming; Eyunni, Sanjana; Goodrum, Andrew; Zhang, Yuping; Apel, Ingrid J.; Siddiqui, Javed; Cao, Xuhong; Shi, Jiaqi; Pitchiaya, Sethuramsundaram; Kumar-Sinha, Chandan; Crawford, Howard C.; Chinnaiyan, Arul M. Share Save
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An essential role for Argonaute 2 in EGFR-KRAS signaling in pancreatic cancer development Shankar, Sunita; Tien, Jean Ching-Yi; Siebenaler, Ronald F.; Chugh, Seema; Dommeti, Vijaya L.; Zelenka-Wang, Sylvia; Wang, Xiao-Ming; Apel, Ingrid J.; Waninger, Jessica; Eyunni, Sanjana; Xu, Alice; Mody, Malay; Goodrum, Andrew; Zhang, Yuping; Tesmer, John J.; Mannan, Rahul; Cao, Xuhong; Vats, Pankaj; Pitchiaya, Sethuramasundaram; Ellison, Stephanie J.; Shi, Jiaqi; Kumar-Sinha, Chandan; Crawford, Howard C.; Chinnaiyan, Arul M. Share Save
Global analysis of human glycosyltransferases reveals novel targets for pancreatic cancer pathogenesis (vol 41, pg 161, 2020) Gupta, Rohitesh; Leon, Frank; Thompson, Christopher M.; Nimmakayala, Ramakrishna; Karmakar, Saswati; Nallasamy, Palanisamy; Chugh, Seema; Prajapati, Dipakkumar R.; Rachagani, Satyanarayana; Kumar, Sushil; Ponnusamy, Moorthy P. Share Save
Global analysis of human glycosyltransferases reveals novel targets for pancreatic cancer pathogenesis Gupta, Rohitesh; Leon, Frank; Thompson, Christopher M.; Nimmakayala, Ramakrishna; Karmakar, Saswati; Nallasamy, Palanisamy; Chugh, Seema; Prajapati, Dipakkumar R.; Rachagani, Satyanarayana; Kumar, Sushil; Ponnusamy, Moorthy P. Share Save
An essential role for Argonaute 2 in mouse models of KRAS-driven cancers Shankar, Sunita; Tien, Jean Ching-Yi; Siebenaler, Ronald F.; Dommeti, Vijaya L.; Zelenka-Wang, Sylvia; Waninger, Jessica; Juckette, Kristin M.; Xu, Alice; Wang, Xiao-Ming; Chugh, Seema; Mody, Malay; Eyunni, Sanjana; Goodrum, Andrew; Tsaloff, Grace; Zhang, Yuping; Apel, Ingrid J.; Siddiqui, Javed; Smith, Richard D.; Carlson, Heather A.; Tesmer, John; Cao, Xuhong; Shi, Jiaqi; Kumar-Sinha, Chandan; Chinnaiyan, Arul M. Share Save
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