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Kyle E. Orwig

pennsylvania commonwealth system of higher education (pcshe)

55H-index
267Paper Count
1.1WCitation Count
Published Papers 104
Publication Date
Fertility preservation in 2026: current landscape in Europe and the United States for children and adolescents undergoing hematopoietic stem cell transplantation—recommendations on behalf of the Westhafen Intercontinental Group
err2026-05-12
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errOAAI
errAndrea Jarisch; Seth J. Rotz; Alessandro Cattoni; Blandine Courbiere; Scott D. Lundy; Kyle E. Orwig; Catherine Poirot; Jean-Hugues Dalle; Rachel Phelan; Tamara Diesch-Furlanetto
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MAIL-IN SEMEN CRYOPRESERVATION TOOLKIT ALLEVIATES SYSTEMIC BARRIERS FOR ADOLESCENT AND YOUNG ADULT PATIENTS
err2026-05-01
err0
PREAI
errSportsman, Derek; Lynch, Elizabeth Gurt; Nolte, Daniel; Safrai, Myriam; Smith, Kristin; Reinecke, Joyce; Morris, Jerrine; Orwig, Kyle E.; Smith, James F.; Li, Yi
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Naproxen and Ibuprofen Exposure Alter the Blood–Testis Barrier in a Novel In Vitro Model
err2026-03-29
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errOAAI
errKrista M. Symosko Crow; In Ki Cho; Robert Clayton Edenfield; Kristen F. Easley; Ana Planinić; Nagham Younis; Elizabeth Waters; James S. McClellan; Amanda Colvin Zielen; Kylie Tager; Carlos Castro; Calvin Simerly; Kyle Orwig; Davor Ježek; Michael Koval; Charles A. Easley IV
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Generation of two isogenic sickle cell disease induced pluripotent stem cell lines from ovarian fibroblasts
err2026-02-01
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errOAAI
errHarancher, Mitchell R.; Myklebust, Livianna K.; Sukhwani, Meena; Kanodia, Charvi; Sheng, Yi; Castro, Carlos A.; Zielen, Amanda M. Colvin; Orwig, Kyle E.
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Decoding the heterogeneity of human undifferentiated spermatogonia reveals RAS-dependent regulation of stem cell fate
err2026-01-23
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errOAAI
errChiara Capponi; Christopher Smith; Alexa Medica; Tung-Chin Hsieh; Kyle E. Orwig; Kun Tan
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Zip Code Overdiagnosis: Disparities in Fertility Preservation for Young Patients
err2025-12-01
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PREAI
errSafrai, Myriam; Colvin Zielen, Amanda; Neelley, Rachel; Wasser, Lauren M.; Chu, Tianjiao; Orwig, Kyle E.
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High Completion Rates for Mail-In Sperm Cryopreservation Across Diverse U.S. Populations: A Prospective Cohort Study
err2025-10-17
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PREAI
errMyriam Safrai; Andre Belarmino; Daniel Nolte; Kristin Smith; Joyce Reinecke; Jerrine Morris; Stacey A. Kenfield; Yi Li; Daniel Civello; Kyle E. Orwig; James F. Smith
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A Report on Testicular Tissue Cryopreservation for Fertility Preservation in Children: Confirmation of Germ Cell Preservation and Few Surgical Complications
err2025-09-01
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PREAI
errMcCauley, Christopher J.; McElhinney, Kathryn L.; Lockart, Barbara A.; Schmitt, Lori; Zielen, Amanda; Orwig, Kyle E.; Reyes-Mugica, Miguel; Johnson, Emilie K.; Lautz, Timothy B.; Laronda, Monica M.; Rowell, Erin E.
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Identification of missense DMC1 variants in males with non-obstructive azoospermia
err2025-08-15
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errOAAI
errNoor Ullah; Christopher Pombar; Rachel Hvasta-Gloria; Andrea J. Berman; Michelle Malizio; Muhammad Jaseem Khan; Rubina Nazli; Sadia Fatima; Antoni Riera-Escamilla; Helen Castillo-Madeen; Agnieszka Malcher; Marta Olszewska; Miguel J. Xavier; Kristiina Lillepea; Avirup Dutta; Carlos A. Castro; Anu Valkna; Rain Inno; Kyle E. Orwig; Donald F. Conrad; Maciej Kurpisz; Joris A. Veltman; Maris Laan; Alexander N. Yatsenko
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Is the time right for transplanting immature testicular tissue or cells to restore male fertility? Expert perspectives on clinical implementation of autotransplantation of cryopreserved testicular tissue or cells for fertility restoration
err2025-07-11
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errOAAI
errMyriam Safrai; Ellen Goossens; Rod T. Mitchell; Kyle E. Orwig; Callista L. Mulder; Ans M.M. van Pelt; Debra A. Gook; Aurélie Feraille; Emily Delgouffe; Jill P. Ginsberg; Jan-Bernd Stukenborg; Kathleen Duffin; Kirsi Jahnukainen; Claus Yding Andersen; Marianne D. van de Wetering; Michael P. Rimmer; Virginie Barraud-Lange; Nina Neuhaus; Sheila Lane; Hooman Sadri-Ardekani; Nathalie Rives; Christine Wyns
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Non-human primates as a translational model for the study of male reproductive health
err2025-07-07
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PREAI
errR. Clayton Edenfield; Jasper C. Bash; Lyndsey E. Shorey-Kendrick; Rahul J. D’Mello; Travis L. Rice-Stitt; Olivia L. Hagen; Jason A. Graham; Kyle E. Orwig; Charles A. Easley; Jason C. Hedges; Carol B. Hanna; Jamie O. Lo
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Normal embryo development needs MEIG1-mediated sperm formation
err2025-03-15
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PREAI
errSheng, Yi; Yap, Yi Tian; Li, Wei; Dhikhirullahi, Opeyemi; Niu, Changmin; Rabbani, Mashiat; Krawetz, Stephen A.; Hammoud, Saher Sue; Orwig, Kyle E.; Zhang, Zhibing
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SATINN v2: automated image analysis for mouse testis histology with multi-laboratory data integration†
err2025-02-17
err0
PREAI
errYang, Ran; Celino-Brady, Fritzie T.; Dunleavy, Jessica E. M.; Vigh-Conrad, Katinka A.; Atkins, Georgia R.; Hvasta, Rachel L.; Pombar, Christopher R. X.; Yatsenko, Alexander N.; Orwig, Kyle E.; O'Bryan, Moira K.; Lima, Ana C.; Conrad, Donald F.
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A 20-year overview of fertility preservation in boys: new insights gained through a comprehensive international survey
err2024-02-16
err14
errOAAI
errDuffin, Kathleen; Neuhaus, Nina; Andersen, Claus Yding; Barraud-Lange, Virginie; Braye, Aude; Eguizabal, Cristina; Feraille, Aurelie; Ginsberg, Jill P.; Gook, Debra; Goossens, Ellen; Jahnukainen, Kirsi; Jayasinghe, Yasmin; Keros, Victoria; Kliesch, Sabine; Lane, Sheila; Mulder, Callista L.; Orwig, Kyle E.; van Pelt, Ans M. M.; Poirot, Catherine; Rimmer, Michael P.; Rives, Nathalie; Sadri-Ardekani, Hooman; Safrai, Myriam; Schlatt, Stefan; Stukenborg, Jan-Bernd; van de Wetering, Marianne D.; Wyns, Christine; Mitchell, Rod T.
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A bioengineered in situ ovary (ISO) supports follicle engraftment and live-births post-chemotherapy
err2023-11-17
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errOAAI
errBuckenmeyer, Michael J.; Sukhwani, Meena; Iftikhar, Aimon; Nolfi, Alexis L.; Xian, Ziyu; Dadi, Srujan; Case, Zachary W.; Steimer, Sarah R.; D'Amore, Antonio; Orwig, Kyle E.; Brown, Bryan N.
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Human immature testicular tissue organ culture: a step towards fertility preservation and restoration
err2023-08-28
err9
errOAAI
errYounis, Nagham; Caldeira-Brant, Andre L.; Chu, Tianjiao; Abdalla, Shtaywy; Orwig, Kyle E.
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In vivo versus in silico assessment of potentially pathogenic missense variants in human reproductive genes
err2023-07-17
err7
errOAAI
errDing, Xinbao; Singh, Priti; Schimenti, Kerry; Tran, Tina N.; Fragoza, Robert; Hardy, Jimmaline; Orwig, Kyle E.; Olszewska, Marta; Kurpisz, Maciej K.; Yatsenko, Alexander N.; Conrad, Donald F.; Yu, Haiyuan; Schimenti, John C.
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Sperm chromatin structure and reproductive fitness are altered by substitution of a single amino acid in mouse protamine 1
err2023-07-17
err7
PREAI
errMoritz, Lindsay; Schon, Samantha B.; Rabbani, Mashiat; Sheng, Yi; Agrawal, Ritvija; Glass-Klaiber, Juniper; Sultan, Caleb; Camarillo, Jeannie M.; Clements, Jourdan; Baldwin, Michael R.; Diehl, Adam G.; Boyle, Alan P.; O'Brien, Patrick J.; Ragunathan, Kaushik; Hu, Yueh-Chiang; Kelleher, Neil L.; Nandakumar, Jayakrishnan; Li, Jun Z.; Orwig, Kyle E.; Redding, Sy; Hammoud, Saher Sue
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