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Cyrus R. Safinya

university of california

67H-index
400Paper Count
1.7WCitation Count
Published Papers 126
Publication Date
A model of the microtubule cytoskeleton of the axon-initial-segment in mixtures of tubulin, tau, and GTP
err2025-12-18
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PREAI
errPhillip Kohl; Chaeyeon Song; Bretton Fletcher; Peter J. Chung; Rebecca L. Best; Herbert P. Miller; Leslie Wilson; Myung Chul Choi; Youli Li; Stuart C. Feinstein; Cyrus R. Safinya
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Multivalent Lipid MVL5 Micellar Nanoparticles Exhibit Increased Paclitaxel Loading with PEGylation Enhancing Cancer Cell Penetration and Cytotoxicity
err2025-07-16
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PREAI
errWilliam S. Fisher; Aria Ghasemizadeh; Sherwin Roshan; Anna Goldstein; Jessica Douglas; Ramon Perez; Youli Li; Kai K. Ewert; Cyrus R. Safinya
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Acidic Conditions Promote Clustering of Cancer Cell Derived Extracellular Vesicles and Enhance their Fusion with Synthetic Liposomes
err2025-02-13
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errOAAI
errFisher, William S.; Douglas, Jessica; Roshan, Sherwin; Perez, Ramon; Wei, Sophia; Roberts, Logan; Ewert, Kai K.; Safinya, Cyrus R.
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Mixtures of Intrinsically Disordered Neuronal Protein Tau and Anionic Liposomes Reveal Distinct Anionic Liposome-Tau Complexes Coexisting with Tau Liquid-Liquid Phase-Separated Coacervates
err2024-09-28
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PREAI
errTchounwou, Christine; Jobanputra, Anjali J.; Lasher, Dylan; Fletcher, Bretton J.; Jacinto, Jorge; Bhaduri, Arjun; Best, Rebecca L.; Fisher, William S.; Ewert, Kai K.; Li, Youli; Feinstein, Stuart C.; Safinya, Cyrus R.
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Complexes of tubulin oligomers and tau form a viscoelastic intervening network cross-bridging microtubules into bundles
err2024-03-15
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errOAAI
errKohl, Phillip A.; Song, Chaeyeon; Fletcher, Bretton J.; Best, Rebecca L.; Tchounwou, Christine; Garcia Arceo, Ximena; Chung, Peter J.; Miller, Herbert P.; Wilson, Leslie; Choi, Myung Chul; Li, Youli; Feinstein, Stuart C.; Safinya, Cyrus R.
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Paclitaxel-Loaded Cationic Fluid Lipid Nanodiscs and Liposomes with Brush-Conformation PEG Chains Penetrate Breast Tumors and Trigger Caspase-3 Activation
err2022-12-15
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errOAAI
errSimon-Gracia, Lorena; Scodeller, Pablo; Fisher, William S.; Sidorenko, Valeria; Steffes, Victoria M.; Ewert, Kai K.; Safinya, Cyrus R.; Teesalu, Tambet
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Cationic Liposomes as Vectors for Nucleic Acid and Hydrophobic Drug Therapeutics
err2021-08-30
err79
errOAAI
errEwert, Kai K.; Scodeller, Pablo; Simon-Gracia, Lorena; Steffes, Victoria M.; Wonder, Emily A.; Teesalu, Tambet; Safinya, Cyrus R.
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Paclitaxel loading in cationic liposome vectors is enhanced by replacement of oleoyl with linoleoyl tails with distinct lipid shapes
err2021-03-31
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errOAAI
errZhen, Yuhong; Ewert, Kai K.; Fisher, William S.; Steffes, Victoria M.; Li, Youli; Safinya, Cyrus R.
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Forced Crowding of Colloids by Thermophoresis and Convection in a Custom Liquid Clusius-Dickel Microdevice
err2021-01-07
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PREAI
errLight, Brandon S.; Zepeda-Rosales, Miguel; Li, Youli; Safinya, Cyrus R.
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Assembly of Building Blocks by Double-End-Anchored Polymers in the Dilute Regime Mediated by Hydrophobic Interactions at Controlled Distances
err2020-09-22
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errOAAI
errWonder, Emily A.; Ewert, Kai K.; Liu, Chenyu; Steffes, Victoria M.; Kwak, Jasmin; Qahar, Vikar; Majzoub, Ramsey N.; Zhang, Zhening; Carragher, Bridget; Potter, Clinton S.; Li, Youli; Qiao, Weihong; Safinya, Cyrus R.
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Tubulin Double Helix: Lateral and Longitudinal Curvature Changes of Tubulin Protofilament
errSMALL
IF12.1
err2020-08-13
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PREAI
errLee, Juncheol; Song, Chaeyeon; Lee, Jimin; Miller, Herbert P.; Cho, Hasaeam; Gim, Bopil; Li, Youli; Feinstein, Stuart C.; Wilson, Leslie; Safinya, Cyrus R.; Choi, Myung Chul
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PEGylation of Paclitaxel-Loaded Cationic Liposomes Drives Steric Stabilization of Bicelles and Vesicles thereby Enhancing Delivery and Cytotoxicity to Human Cancer Cells
err2019-12-10
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errOAAI
errSteffes, Victoria M.; Zhang, Zhening; MacDonald, Scott; Crowe, John; Ewert, Kai K.; Carragher, Bridget; Potter, Clinton S.; Safinya, Cyrus R.
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A Multifunctional Lipid Incorporating Active Targeting and Dual-Control Release Capabilities for Precision Drug Delivery
err2019-11-27
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PREAI
errLiu, Chenyu; Ewert, Kai K.; Yao, Weihe; Wang, Ning; Li, Youli; Safinya, Cyrus R.; Qiao, Weihong
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A multifunctional lipid that forms contrast-agent liposomes with dual-control release capabilities for precise MRI-guided drug delivery
err2019-11-01
err54
PREAI
errLiu, Chenyu; Ewert, Kai K.; Wang, Ning; Li, Youli; Safinya, Cyrus R.; Qiao, Weihong
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Minireview - Microtubules and Tubulin Oligomers: Shape Transitions and Assembly by Intrinsically Disordered Protein Tau and Cationic Biomolecules
err2019-09-20
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errOAAI
errSafinya, Cyrus R.; Chung, Peter J.; Song, Chaeyeon; Li, Youli; Miller, Herbert P.; Choi, Myung Chul; Raviv, Uri; Ewert, Kai K.; Wilson, Leslie; Feinstein, Stuart C.
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3D Columnar Phase of Stacked Short DNA Organized by Coherent Membrane Undulations
err2019-08-13
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errOAAI
errBouxsein, Nathan F.; Leal, Cecilia; McAllister, Christopher S.; Li, Youli; Ewert, Kai K.; Samuel, Charles E.; Safinya, Cyrus R.
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Condensation of Divalent Metail Ions by Map-Tau Remodels Tau-Microtubule Bundle Architecture
err2019-02-01
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errOAAI
errFletcher, Bretton; Song, Chaeyeon; Kohl, Phillip; Chung, Peter J.; Miller, Herbert; Li, Youli; Choi, Myung Chul; Wilson, Leslie; Feinstein, Stuart C.; Safinya, Cyrus R.
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Lipid Nanomaterials for Paclitaxel Delivery in Cancer Therapeutics: Effect of Pegylation and Charge on the Morphology and Efficacy
err2019-02-01
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errOAAI
errSteffes, Victoria; Zhang, Zhening; Crowe, John; MacDonald, Scott; Ewert, Kai K.; Carragher, Bridget; Potter, Clinton S.; Safinya, Cyrus R.
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The Effect of Site-Specific Acetylation Based Tau Mutations on Tau-Microtubule Associations
err2019-02-01
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errOAAI
errTchounwou, Christine; Fletcher, Bretton; Song, Chaeyeon; Kohl, Phillip A.; Chung, Peter J.; Miller, Herb P.; Li, Youli; Choi, Myung-Chul; Wilson, Leslie; Feinstein, Stuart C.; Safinya, Cyrus R.
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