Laurens De Sadeleer - Publications, H-index & Citations

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Laurens De Sadeleer

ku leuven

18H-index

117Paper Count

1.5KCitation Count

Published Papers 59

Publication Date

The pleuroparenchymal fibroelastosis atlas reveals aberrant cell states and their zonation as an alternate roadmap to lung fibrosis

Science Advances

IF12.5

2026-05-08

OAAI

Jannik Ruwisch; Aurélie Cazes; Lena M. Leiber; Raphaël Borie; Lavinia Neubert; Leonard Christian; Vincent Thomas de Montpréville; Adam Szmul; Farah Moussa; Stijn E. Verleden; Svenja Gaedcke; Jan Hegermann; Jan Fuge; Matthias Ballmaier; Jan C. Kamp; Mark Greer; Peter Braubach; Christopher Werlein; Fabius Ius; Theresa Graalmann; Kalil Aburahma; Laurens J. De Sadeleer; Ryoko Egashira; Maximilian Ackermann; Daisuke Yamada; Marius M. Hoeper; Christine Falk; Jens Gottlieb; Herbert B. Schiller; Bart Vanaudenaerde; Benjamin Seeliger; Marie-Pierre Debray; Jean Francois Bernaudin; Lars Knudsen; Emmanuel Bergot; Joseph Jacob; Hervé Mal; Danny Jonigk; Sabine Dettmer; Pierre Mordant; Antje Prasse; Elie Fadel; Wim A. Wuyts; Bruno Crestani; Naftali Kaminski; Aurélien Justet; Jonas C. Schupp

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Histological proof of pulmonary herpesvirus presence in patients with COVID-19- or influenza-related ARDS

Critical Care

IF9.3

2026-04-02

OAAI

Jannes Heylen; Boaz Lopuhaä; Lore Vanderbeke; Simon Feys; Lenn Maessen; Cato Jacobs; Hanne Moon Lauwers; Kurt Beuselinck; Greet De Vlieger; Laurens De Sadeleer; Greet Hermans; Katrien Lagrou; Philippe Meersseman; Wouter Meersseman; Marijke Peetermans; Eric Van Wijngaerden; Alexander Wilmer; Georges M. Verjans; Thierry P. P. van den Bosch; Jan H. von der Thüsen; Gert De Hertogh; Jeroen J. A. van Kampen; Joost Wauters

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Newly Onset Dyspnea During Pregnancy

CHEST

IF8.6

2025-10-08

OAAI

Marie Vermant; Valerie Van Ballaer; Tine Follet; Eveline Claeys; Samuel De Bontridder; Nico De Crem; Adriana Dubbeldam; Alexandros Kalkanis; Laurens J. De Sadeleer; Ellen De Langhe; Wim A. Wuyts

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A deep generative model for deciphering cellular dynamics and in silico drug discovery in complex diseases

Nature Biomedical Engineering

IF26.6

2025-06-20

OAAI

Yumin Zheng; Jonas C. Schupp; Taylor Adams; Geremy Clair; Aurelien Justet; Farida Ahangari; Xiting Yan; Paul Hansen; Marianne Carlon; Emanuela Cortesi; Marie Vermant; Robin Vos; Laurens J. De Sadeleer; Ivan O. Rosas; Ricardo Pineda; John Sembrat; Melanie Königshoff; John E. McDonough; Bart M. Vanaudenaerde; Wim A. Wuyts; Naftali Kaminski; Jun Ding

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ABCE1: A new cytoplasmic autoantibody target in systemic sclerosis-associated interstitial lung disease

AUTOIMMUNITY REVIEWS

IF8.3

2025-04-01

PREAI

Vulsteke, Jean-Baptiste; Lenaerts, Jan; Dillaerts, Doreen; Verschueren, Patrick; Wuyts, Wim A.; De Crem, Nico; De Sadeleer, Laurens; Vos, Robin; De Langhe, Ellen; Bossuyt, Xavier

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Outpatient parenteral antibiotic therapy in non-cystic fibrosis lung transplant recipients: characteristics, efficacy and safety ( Aug , 10.1007/ s 10096-024-04921-9 , 2024)

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

IF3

2025-03-01

OAAI

Forier, Bart; Schaevers, Veronique; Spriet, Isabel; Quintens, Charlotte; Desmet, Stefanie; Bos, Saskia; Van Bleyenbergh, Pascal; Lorent, Natalie; De Sadeleer, Laurens; Godinas, Laurent; Dupont, Lieven J.; Vos, Robin

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Epigenetic age acceleration in idiopathic pulmonary fibrosis revealed by DNA methylation clocks

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

IF3.5

2025-02-19

PREAI

Kurbanov, DB; Ahangari, F; Adams, T; De Man, R; Tang, J; Carlon, M; Abu Hussein, N; Cortesi, E; Zapata, M; De Sadelaar, L; Wuyts, W; Vanaudenaerde, B; Kaminski, N; McDonough, JE

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Clinical predictors for restrictive allograft syndrome: A nested case-control study

American Journal of Transplantation

IF8.2

2025-01-31

PREAI

Hanne Beeckmans; Pieterjan Kerckhof; Nilufer Acet Öztürk; Andrea Zajacova; Jan Van Slambrouck; Saskia Bos; Marie Vermant; Lyne O. Van Dieren; Tessa Goeminne; Christelle Vandervelde; Josephine Bardyn; Elisabeth Willems; Sam Lauriers; Marius Brusselmans; Leen Van Langenhoven; Marie Paule Emonds; Steffi De Pelsmaeker; Johan Kerkhofs; Laurens De Sadeleer; Laurent Godinas; Lieven J. Dupont; Dirk E.Van Raemdonck; Laurens J. Ceulemans; Bart M. Vanaudenaerde; Robin Vos

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Thoracic ultrasound to detect interstitial lung disease associated with rheumatoid arthritis: comparing three protocols

EUROPEAN RESPIRATORY JOURNAL

IF21

2024-10-30

PREAI

Vermant, Marie; Kalkanis, Alexandros; Jacob, Joseph; Goos, Tinne; Cortesi, Emanuela Elsa; Cypers, Heleen; De Crem, Nico; Gogaert, Stefan; Neerinckx, Barbara; Taelman, Veerle; Veyt, Nathalie; De Sadeleer, Laurens J.; Verschueren, Patrick; Wuyts, Wim A.

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Long-term survival after High-Urgent lung transplantation: a single center analysis

EUROPEAN RESPIRATORY JOURNAL

IF21

2024-10-30

PREAI

Vanluyten, Cedric; Denaux, Karen; Claes, Dirk; Peetermans, Marijke; Wauters, Joost; Meersseman, Philippe; Hermans, Greet; Ingels, Catherine; Neyrinck, Arne P.; Van Slambrouck, Jan; Van Raemdonck, Dirk E.; Beeckmans, Hanne; De Sadeleer, Laurens; Godinas, Laurent; Dupont, Lieven; Ceulemans, Laurens J.; Vos, Robin

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Machine learning of spirometry may predict CLAD onset after lung transplantation

EUROPEAN RESPIRATORY JOURNAL

IF21

2024-10-30

PREAI

Kerckhof, Pieterjan; Verstraete, Kenneth; Beeckmans, Hanne; De Sadeleer, Laurens; Mcdonough, John; Vanaudenaerde, Bart; Vos, Robin

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LSC-2024-Deciphering the spatial heterogeneity of interstitial lung disease by integrative radiomics and single-nucleus transcriptomics

EUROPEAN RESPIRATORY JOURNAL

IF21

2024-10-30

PREAI

Ammeter, Michael; Chen, Yuexin; Mueller, Michaela; Zhou, Shuhong; De Sadeleer, Laurens J.; Brunner, Matthias; Distler, Oliver; Gabrys, Hubert S.; Tanadini-Lang, Stephanie; Luecken, Malte D.; Verleden, Stijn; Maurer, Britta; Schiller, Herbert B.; Gote-Schniering, Janine

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Outpatient parenteral antibiotic therapy in non-cystic fibrosis lung transplant recipients: characteristics, efficacy and safety

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

IF3

2024-08-28

OAAI

Bart, Forier; Veronique, Schaevers; Isabel, Spriet; Charlotte, Quintens; Stefanie, Desmet; Saskia, Bos; Pascal, Van Bleyenbergh; Natalie, Lorent; Laurens, De Sadeleer; Laurent, Godinas; Lieven, J. Dupont; Robin, Vos

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EXPLORING POTENTIAL SCREENING TOOLS FOR INTERSTITIAL LUNG DISEASE IN RHEUMATOID ARTHRITIS

ANNALS OF THE RHEUMATIC DISEASES

IF20.6

2024-06-01

PREAI

Vermant, M.; Kalkanis, A.; Jacob, J.; Goos, T.; Cortesi, E. E.; Cypers, H.; De Crem, N.; Gogaert, S.; Neerinckx, B.; Taelman, V.; Veyt, N.; De Sadeleer, L.; Verschueren, P.; Wuyts, W.

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Ventilatory capacity in CLAD is driven by dysfunctional airway structure

EBIOMEDICINE

IF10.8

2024-03-01

OAAI

Kerckhof, Pieterjan; Ambrocio, Gene P. L.; Beeckmans, Hanne; Kaes, Janne; Geudens, Vincent; Bos, Saskia; Willems, Lynn; Vermaut, Astrid; Vermant, Marie; Goos, Tinne; De Fays, Charlotte; Aversa, Lucia; Mohamady, Yousry; Vanstapel, Arno; Orlitova, Michaela; Van Slambrouck, Jan; Jin, Xin; Varghese, Vimi; Josipovic, Ivan; Boone, Matthieu N.; Dupont, Lieven J.; Weynand, Birgit; Dubbeldam, Adriana; Van Raemdonck, Dirk E.; Ceulemans, Laurens J.; Gayan-Ramirez, Ghislaine; Sadeleer, Laurens J. De; Mcdonough, John E.; Vanaudenaerde, Bart M.; Vas, Robin

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Sfrp1 inhibits lung fibroblast invasion during transition to injury-induced myofibroblasts

EUROPEAN RESPIRATORY JOURNAL

IF21

2024-01-11

OAAI

Mayr, Christoph H.; Sengupta, Arunima; Asgharpour, Sara; Ansari, Meshal; Pestoni, Jeanine C.; Ogar, Paulina; Angelidis, Ilias; Liontos, Andreas; Rodriguez-Castillo, Jose Alberto; Lang, Niklas J.; Strunz, Maximilian; Porras-Gonzalez, Diana; Gerckens, Michael; De Sadeleer, Laurens J.; Oehrle, Bettina; Viteri-Alvarez, Valeria; Fernandez, Isis E.; Tallquist, Michelle; Irmler, Martin; Beckers, Johannes; Eickelberg, Oliver; Stoleriu, Gabriel Mircea; Behr, Juergen; Kneidinger, Nikolaus; Wuyts, Wim A.; Wasnick, Roxana Maria; Yildirim, Ali Oender; Ahlbrecht, Katrin; Morty, Rory E.; Samakovlis, Christos; Theis, Fabian J.; Burgstaller, Gerald; Schiller, Herbert B.

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Ex vivo tissue perturbations coupled to single-cell RNA-seq reveal multilineage cell circuit dynamics in human lung fibrogenesis

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2023-12-06

OAAI

Lang, Niklas J.; Gote-Schniering, Janine; Porras-Gonzalez, Diana; Yang, Lin; De Sadeleer, Laurens J.; Jentzsch, R. Christoph; Shitov, Vladimir A.; Zhou, Shuhong; Ansari, Meshal; Agami, Ahmed; Mayr, Christoph H.; Hooshiar Kashani, Baharak; Chen, Yuexin; Heumos, Lukas; Pestoni, Jeanine C.; Molnar, Eszter Sarolta; Geeraerts, Emiel; Anquetil, Vincent; Saniere, Laurent; Woegrath, Melanie; Gerckens, Michael; Lehmann, Mareike; Yildirim, Ali Onder; Hatz, Rudolf; Kneidinger, Nikolaus; Behr, Juergen; Wuyts, Wim A.; Stoleriu, Mircea-Gabriel; Luecken, Malte D.; Theis, Fabian J.; Burgstaller, Gerald; Schiller, Herbert B.

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Intrafamilial Correlation and Variability in the Clinical Evolution of Pulmonary Fibrosis

CHEST

IF8.6

2023-12-01

OAAI

Goos, Tinne; Dubbeldam, Adriana; Vermant, Marie; Gogaert, Stefan; De Sadeleer, Laurens J.; De Crem, Nico; De Langhe, Ellen; Yserbyt, Jonas; Weynand, Birgit; Carlon, Marianne S.; Verschakelen, Johny; Vermeer, Sascha; Verleden, Stijn E.; Wuyts, Wim A.

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Mortality surrogates in combined pulmonary fibrosis and emphysema

EUROPEAN RESPIRATORY JOURNAL

IF21

2023-11-16

OAAI

Zhao, An; Gudmundsson, Eyjolfur; Mogulkoc, Nesrin; van Moorsel, Coline; Corte, Tamera J.; Vasudev, Pardeep; Romei, Chiara; Chapman, Robert; Wallis, Tim J. M.; Denneny, Emma; Goos, Tinne; Savas, Recep; Ahmed, Asia; Brereton, Christopher J.; Es, Hendrik W. van; Jo, Helen; De Liperi, Annalisa; Duncan, Mark; Pontoppidan, Katarina; Sadeleer, Laurens J. De; van Beek, Frouke; Barnett, Joseph; Cross, Gary; Procter, Alex; Veltkamp, Marcel; Hopkins, Peter; Moodley, Yuben; Taliani, Alessandro; Taylor, Magali; Verleden, Stijn; Tavanti, Laura; Vermant, Marie; Nair, Arjun; Stewart, Iain; Janes, Sam M.; Young, Alexandra L.; Barber, David; Alexander, Daniel C.; Porter, Joanna C.; Wells, Athol U.; Jones, Mark G.; Wuyts, Wim A.; Jacob, Joseph

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Ex vivo tissue perturbations coupled to single-cell RNA-seq reveal multi-lineage cell circuit dynamics in human lung fibrogenesis

EUROPEAN RESPIRATORY JOURNAL

IF21

2023-10-27

OAAI

Lang, Niklas Jonathan; Gote-Schniering, Janine; Porras-Gonzalez, Diana; Yang, Lin; De Sadeleer, Laurens J.; Jentzsch, R. Christoph; Shitov, Vladimir A.; Zhou, Shuhong; Ansari, Meshal; Agami, Ahmed; Mayr, Christoph H.; Kashani, Baharak Hooshiar; Chen, Yuexin; Heumos, Lukas; Pestoni, Jeanine C.; Geeraerts, Emil; Anquetil, Vincent; Saniere, Laurent; Woegrath, Melanie; Gerckens, Michael; Hatz, Rudolf; Kneidinger, Nikolaus; Behr, Juergen; Wuyts, Wim A.; Stoleriu, Mircea-Gabriel; Luecken, Malte D.; Theis, Fabian J.; Burgstaller, Gerald; Schiller, Herbert. B.

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Research Directions