Regis J. O’Keefe - Publications, H-index & Citations

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Regis J. O’Keefe

washington university

91H-index

402Paper Count

2.7WCitation Count

Published Papers 160

Publication Date

Experimentally Induced Femoroacetabular Impingement Results in Hip Osteoarthritis (vol 107, pg 1200, 2025)

Journal of Bone and Joint Surgery-American Volume

IF4.3

2026-01-21

PREAI

Kamenaga, Tomoyuki; Kikuchi, Kenichi; O'Keefe, Regis J.; Clohisy, John C.; Pascual-Garrido, Cecilia

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NFIA regulates articular chondrocyte fatty acid metabolism and joint homeostasis

Science Translational Medicine

IF14.6

2025-07-30

PREAI

Cuicui Wang; Liang Fang; Meng Shi; Xiangfeng Niu; Tiandao Li; Xiaofei Li; Kevin Cho; Yonghua He; Shuang Liu; Aiwu Lu; Xiaoyun Xing; Jessica Lukowski; Young Ah Goo; John R. Speakman; Di Chen; Regis J. O’Keefe; Gary J. Patti; Michael J. Zuscik; Bo Zhang; Jie Shen

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Statistical Shape Modeling of an Experimental, Induced Cam-Femoroacetabular Impingement Deformity in a Rabbit Model: A Platform to Study Mechanism of Hip Disease

AMERICAN JOURNAL OF SPORTS MEDICINE

IF4.5

2025-03-01

PREAI

Ince, Deniz C.; Kamenaga, Tomoyuki; Kikuchi, Kenichi; Clohisy, John C.; O'Keefe, Regis J.; Yuh, Catherine; Wimmer, Markus A.; Mell, Steven P.; Pascual-Garrido, Cecilia

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Rapid Manufacturing, Regulatory Approval, and Utilization of Patient-specific 3D-Printed Titanium Implants for Complex Multistage Spinal Surgeries

GLOBAL SPINE JOURNAL

IF3

2025-02-17

OAAI

Alexander T. Yahanda; Karma Barot; Miguel A. Ruiz-Cardozo; Mitchell A. Pet; Ian English; J. Westley Ohman; Luis A. Sanchez; Steven R. Hunt; David M. Brogan; Regis J. O’Keefe; Brian Albers; Evan Miller; Matthew L. Goodwin; Camilo A. Molina

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Targeted deletion of Minpp1 provides new insight into the activity of multiple inositol polyphosphate phosphatase in vivo

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

OAAI

Chi, HB; Yang, XN; Kingsley, PD; O'Keefe, RJ; Puzas, JE; Rosier, RN; Shears, SB; Reynolds, PR

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Otto Aufranc Award: Identification of Key Molecular Players in the Progression of Hip Osteoarthritis Through Transcriptomes and Epigenetics

JOURNAL OF ARTHROPLASTY

IF3.8

2022-07-01

OAAI

Pascual-Garrido, Cecilia; Kamenaga, Tomoyuki; Brophy, Robert H.; Shen, Jie; O'Keefe, Regis J.; Clohisy, John C.

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A Novel Model of Hip Femoroacetabular Impingement in Immature Rabbits Reproduces the Distinctive Head-Neck Cam Deformity

AMERICAN JOURNAL OF SPORTS MEDICINE

IF4.5

2022-04-13

OAAI

Kamenaga, Tomoyuki; Haneda, Masahiko; Brophy, Robert H.; O'Keefe, Regis J.; Clohisy, John C.; Pascual-Garrido, Cecilia

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Systemic inhibition or global deletion of CaMKK2 protects against post-traumatic osteoarthritis

OSTEOARTHRITIS AND CARTILAGE

IF9

2022-01-01

OAAI

Mevel, E.; Shutter, J. A.; Ding, X.; Mattingly, B. T.; Williams, J. N.; Li, Y.; Huls, A.; Kambrath, A., V; Trippel, S. B.; Wagner, D.; Allen, M. R.; O'Keefe, R.; Thompson, W. R.; Burr, D. B.; Sankar, U.

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Deletion of Glut1 in early postnatal cartilage reprograms chondrocytes toward enhanced glutamine oxidation

BONE RESEARCH

IF15

2021-08-23

OAAI

Wang, Cuicui; Ying, Jun; Niu, Xiangfeng; Li, Xiaofei; Patti, Gary J.; Shen, Jie; O'Keefe, Regis J.

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In Memory of Prof. Harry Genant, MD/PhD

JOURNAL OF ORTHOPAEDIC TRANSLATION

IF7.8

2021-03-01

OAAI

Yu, Wei; Cheng, Xiao-Guang; O'Keefe, Regis J.; Chen, Min; Qin, Ling

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FoxO1 is a crucial mediator of TGF-β/TAK1 signaling and protects against osteoarthritis by maintaining articular cartilage homeostasis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-11-16

OAAI

Wang, Cuicui; Shen, Jie; Ying, Jun; Xiao, Ding; O'Keefe, Regis J.

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Distinct Pattern of Inflammation of Articular Cartilage and the Synovium in Early and Late Hip Femoroacetabular Impingement

AMERICAN JOURNAL OF SPORTS MEDICINE

IF4.5

2020-07-31

OAAI

Haneda, Masahiko; Rai, Muhammad Farooq; Cai, Lei; Brophy, Robert H.; O'Keefe, Regis J.; Clohisy, John C.; Pascual-Garrido, Cecilia

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LDHA-mediated ROS generation in chondrocytes is a potential therapeutic target for osteoarthritis

NATURE COMMUNICATIONS

IF15.7

2020-07-09

230

OAAI

Arra, Manoj; Swarnkar, Gaurav; Ke, Ke; Otero, Jesse E.; Ying, Jun; Duan, Xin; Maruyama, Takashi; Rai, Muhammad Farooq; O'Keefe, Regis J.; Mbalaviele, Gabriel; Shen, Jie; Abu-Amer, Yousef

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Runx2 plays a central role in Osteoarthritis development

JOURNAL OF ORTHOPAEDIC TRANSLATION

IF7.8

2020-07-01

OAAI

Chen, Di; Kim, Dongyeon J.; Shen, Jie; Zou, Zhen; O'Keefe, Regis J.

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Inflammatory Response of Articular Cartilage to Femoroacetabular Impingement in the Hip

AMERICAN JOURNAL OF SPORTS MEDICINE

IF4.5

2020-05-08

OAAI

Haneda, Masahiko; Rai, Muhammad Farooq; O'Keefe, Regis J.; Brophy, Robert H.; Clohisy, John C.; Pascual-Garrido, Cecilia

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RNA-seq analysis of chondrocyte transcriptome reveals genetic heterogeneity in LG/J and SM/J murine strains

OSTEOARTHRITIS AND CARTILAGE

IF9

2020-04-01

OAAI

Duan, X.; Cai, L.; Schmidt, E. J.; Shen, J.; Tycksen, E. D.; O'Keefe, R. J.; Cheverud, J. M.; Rai, M. F.

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Dnmt3b ablation impairs fracture repair through upregulation of Notch pathway

JCI INSIGHT

IF6.1

2020-02-13

OAAI

Ying, Jun; Xu, Taotao; Wang, Cuicui; Jin, Hongting; Tong, Peijian; Guan, Jianjun; Abu-Amer, Yousef; O'Keefe, Regis; Shen, Jie

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Clinician-directed treatment guidelines

JOURNAL OF ORTHOPAEDIC TRANSLATION

IF7.8

2020-01-01

OAAI

O'Keefe, Regis; Hopkins, Chelsea; Qin, Ling

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Patient-Reported Outcomes Measurement Information System physical function correlates with Toronto Extremity Salvage Score in an orthopaedic oncology population

JOURNAL OF ORTHOPAEDIC TRANSLATION

IF7.8

2019-10-01

OAAI

Ploetze, Kristen L.; Dalton, Jay F.; Calfee, Ryan P.; McDonald, Douglas J.; O'Keefe, Regis J.; Cipriano, Cara A.

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American Society for Bone and Mineral Research-Orthopaedic Research Society Joint Task Force Report on Cell-Based Therapies

JOURNAL OF BONE AND MINERAL RESEARCH

IF5.9

2019-09-23

OAAI

O'Keefe, Regis J.; Tuan, Rocky S.; Lane, Nancy E.; Barry, Frank; Bunnell, Bruce A.; Colnot, Celine; Drake, Matthew T.; Drissi, Hicham; Fortier, Lisa A.; Guldberg, Robert E.; Little, David G.; Marshall, Mary F.; Mao, Jeremy J.; Nakamura, Norimasa; Robey, Pamela G.; Rosen, Vicki; Rowe, David W.; Schwarz, Edward M.

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Research Directions