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Characterization of Rationally Designed CRISPR/Cas9-Based DNA Methyltransferases with Distinct Methyltransferase and Gene Silencing Activities in Human Cell Lines and Primary Human T Cells Guerra-Resendez, Rosa Selenia; Lydon, Samantha LeGoff; Ma, Alex J.; Bedford, Guy C.; Reed, Daniel R.; Kim, Sunghwan; Teran, Erik R.; Nishiguchi, Tomoki; Escobar, Mario; Dinardo, Andrew R.; Hilton, Isaac B. Share Save
BCG-Induced DNA Methylation Changes Improve Coronavirus Disease 2019 Vaccine Immunity Without Decreasing the Risk for Severe Acute Respiratory Syndrome Coronavirus 2 Infection Longlax, Santiago Carrero; Koster, Kent J.; Kamat, Ashish M.; Lozano, Marisa; Lerner, Seth P.; Hannigan, Rebecca; Nishiguchi, Tomoki; Abhimanyu, Daanish; Sheikh, Daanish; Ladki, Malik; Portillo, Alexandra; Koirala, Amrit; Patel, Tajhal D.; Spieler, Zoe; Benjamin, Aaron B.; Lebedev, Maxim; Ofili, Theresa U.; Hutchison, Robert W.; Udeani, George; Opperman, Lynne A.; Neal, Gabriel; Mandalakas, Anna M.; Netea, Mihai G.; Arditi, Moshe; Avalos, Pablo; Grimm, Sandra L.; Coarfa, Cristian; Cirillo, Jeffrey D.; DiNardo, Andrew R. Share Save
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TCA metabolism regulates DNA hypermethylation in LPS and Mycobacterium tuberculosis-induced immune tolerance Abhimanyu; Longlax, Santiago Carrero; Nishiguchi, Tomoki; Ladki, Malik; Sheikh, Daanish; Martinez, Amera L.; Mace, Emily M.; Grimm, Sandra L.; Caldwell, Thaleia; Varela, Alexandra Portillo; V. Sekhar, Rajagopal; Mandalakas, Anna M.; Mlotshwa, Mandla; Ginidza, Sibuse; Cirillo, Jeffrey D.; Wallis, Robert S.; Netea, Mihai G.; van Crevel, Reinout; Coarfa, Cristian; Dinardo, Andrew R. Share Save
Perforin production by T cells and Natural Killer cells in CMV-reactivated allogeneic cell transplant patients is associated with early post-transplant death Sheikh, Daanish; Nesher, Lior; Khawaja, Fareed; Shields, Christina; Grimbergen, Andrea; Nahmod, Karen; Longlax, Santiago Carrero; Ladki, Malik; Nishiguchi, Tomoki; Chemaly, Roy; Makedonas, George; Dinardo, Andrew Share Save
Interleukin-18 as a severity marker and novel potential therapeutic target for epidermolytic ichthyosis Ansai, Osamu; Miyauchi, Toshinari; Hayashi, Ryota; Katsumi, Tatsuya; Nishiguchi, Tomoki; Hasegawa, Akito; Shinkuma, Satoru; Natsuga, Ken; Nomura, Toshifumi; Shimomura, Yutaka; Abe, Riichiro Share Save
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Increased DNA methylation, cellular senescence and premature epigenetic aging in guinea pigs and humans with tuberculosis Bobak, Carly A.; Abhimanyu; Natarajan, Harini; Gandhi, Tanmay; Grimm, Sandra L.; Nishiguchi, Tomoki; Koster, Kent; Longlax, Santiago Carrero; Dlamini, Qiniso; Kahari, Jacquiline; Mtetwa, Godwin; Cirillo, Jeffrey D.; O'Malley, James; Hill, Jane E.; Coarfa, Cristian; DiNardo, Andrew R. Share Save
Gene expression signatures identify biologically and clinically distinct tuberculosis endotypes DiNardo, Andrew R.; Gandhi, Tanmay; Heyckendorf, Jan; Grimm, Sandra L.; Rajapakshe, Kimal; Nishiguchi, Tomoki; Reimann, Maja; Kirchner, H. Lester; Kahari, Jaqueline; Dlamini, Qiniso; Lange, Christoph; Goldmann, Torsten; Marwitz, Sebastian; DZIF-TB Cohort Study Grp; Abhimanyu, Jeffrey D.; Cirillo, Jeffrey D.; Kaufmann, Stefan H. E.; Netea, Mihai G.; van Crevel, Reinout; Mandalakas, Anna M.; Coarfa, Cristian Share Save
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Tuberculosis endotypes to guide stratified host-directed therapy DiNardo, Andrew R.; Nishiguchi, Tomoki; Grimm, Sandra L.; Schlesinger, Larry S.; Graviss, Edward A.; Cirillo, Jeffrey D.; Coarfa, Cristian; Mandalakas, Anna M.; Heyckendorf, Jan; Kaufmann, Stefan H. E.; Lange, Christoph; Netea, Mihai G.; Van Crevel, Reinout Share Save
Perspective for Precision Medicine for Tuberculosis Lange, Christoph; Aarnoutse, Rob; Chesov, Dumitru; van Crevel, Reinout; Gillespie, Stephen H.; Grobbel, Hans-Peter; Kalsdorf, Barbara; Kontsevaya, Irina; van Laarhoven, Arjan; Nishiguchi, Tomoki; Mandalakas, Anna; Merker, Matthias; Niemann, Stefan; Koehler, Niklas; Heyckendorf, Jan; Reimann, Maja; Ruhwald, Morten; Sanchez-Carballo, Patricia; Schwudke, Dominik; Waldow, Franziska; DiNardo, Andrew R. Share Save
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DNA hypermethylation during tuberculosis dampens host immune responsiveness Dinardo, Andrew R.; Rajapakshe, Kimal; Nishiguchi, Tomoki; Grimm, Sandra L.; Mtetwa, Godwin; Dlamini, Qiniso; Kahari, Jaquiline; Mahapatra, Sanjana; Kay, Alexander; Maphalala, Gugu; Mace, Emily M.; Makedonas, George; Cirillo, Jeffrey D.; Netea, Mihai G.; Van Crevel, Reinout; Coarfa, Cristian; Mandalakas, Anna M. Share Save
Schistosomiasis Induces Persistent DNA Methylation and Tuberculosis-Specific Immune Changes DiNardo, Andrew R.; Nishiguchi, Tomoki; Mace, Emily M.; Rajapakshe, Kimal; Mtetwa, Godwin; Kay, Alexander; Maphalala, Gugu; Secor, W. Evan; Mejia, Rojelio; Orange, Jordan S.; Coarfa, Cristian; Bhalla, Kapil N.; Graviss, Edward A.; Mandalakas, Anna M.; Makedonas, George Share Save
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Intracellular haemolytic agents of Heterocapsa circularisquama exhibit toxic effects on H-circularisquama cells themselves and suppress both cell-mediated haemolytic activity and toxicity to rotifers (Brachionus plicatilis) Nishiguchi, Tomoki; Cho, Kichul; Yasutomi, Masumi; Ueno, Mikinori; Yamaguchi, Kenichi; Basti, Leila; Yamasaki, Yasuhiro; Takeshita, Satoshi; Kim, Daekyung; Oda, Tatsuya Share Save
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