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李

李燕|Yan Li

Anhui University of Technology访问学者
H-index:43
Citation Count:5,637
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Biography

"李燕教授于2001年至2007年在四川大学华西基础与法医学院攻读医学微生物学硕士、博士学位。毕业后在四川大学华西口腔医(学)院/口腔疾病防治全国重点实验室工作。2009年到美国亚利桑那州立大学进行师资培训,2011年赴美国加州大学洛杉矶分校牙学院和俄克拉荷马大学做访问学者。多年来主要从事牙周炎与全身系统性疾病免疫病理机制相关研究、口腔鳞癌肿瘤微环境免疫机制研究和口腔微生物组结构功能解析。多次获得国家自然科学基金(81771085,81172579和30901689),四川省科技支撑计划项目(2013SZ0039,2020YFSY0008)及省卫计委重点项目(16ZD021)支持。参与多项国家自然科学基金、十二五、973前期、国际合作、国家自然科学基金重点等重大项目的研究工作。兼任中华口腔医学会口腔生物委员会委员,四川省口腔病理专委会副主委兼秘书。《华西口腔医学杂志》审稿专家。以第一作者、通讯作者发表英文文章30余篇,主/参编专著8部,研究成果发表在卓越期刊ISME J、Cell Death and Dis、Mol Cancer、Intern J Oral Sci、mSystems等杂志。\n代表性论著\n1. Huixu; Zhao Lei; Cheng Lei; Deng Ye; Li Yan; Oral Microbiota from Periodontitis Promote Oral Squamous Cell Carcinoma Development via γδ T Cell Activation, MSystems, 2022, 7(5): e0046922.\n2. He Jinzhi; Shen Xin; Fu Di; Yang Yutao; Xiong Kaixin; Zhao Lei; Xie Huixu; Pelekos Georege; Li Yan ; Human periodontitis-associated salivary microbiome affects the immune response of diabetic mice, Journal of Oral Microbiology, 2022, 14(1): 2107814\n3. Zhang Bo; Miao Tianyu; Shen Xin; Bao Lirong; Zhang Cheng; Yan Caixia; Wei Wei; Chen Jiao; Xiao Liying; Sun Chongkui; Du Jintao; Li Yan; EB virus-induced ATR activation accelerates nasopharyngeal carcinoma growth via M2-type macrophages polarization, Cell Death & Disease, 2020, 11(9): 742.\n4. Sun Chongkui; Luo Xiaobo; Gou Yaping; Hu ling; Wang kun; Li Chao; Xiang zhengting; Zhang Ping; Kong xiangli; Zhang chaoliang; Yang Qin; Li Jing; Xiao Liying; Li Yan; Chen Qianming ; TCAB1: a potential target for diagnosis and therapy of head and neck carcinomas, Molecular Cancer, 2014, 13(1): 180-185.\n5. Yan Li, Jinzhi He, Zhili He, Yuan Zhou, Mengting Yuan, Xin Xu, Feifei Sun, Chengcheng Liu, Jiyao Li, Wenbo Xie, Ye Deng, Yujia Qin, Joy D VanNostrand, Liying Xiao, Liyou Wu, Jizhong Zhou, Wenyuan Shi, Xuedong Zhou. Phylogenetic and functional gene structure shifts of the oral microbiomes in periodontitis patients. ISME J. 2014 Sep;8(9):1879-91."

Education

  • 2001.01 – 2007.12

    四川大学华西基础与法医学院 硕士、博士学位 医学微生物学

Work Experience

  • 2011.01 – 至今

    美国加州大学洛杉矶分校牙学院

    访问学者

  • 2011.01 – 至今

    俄克拉荷马大学

    访问学者

  • 2009.01 – 至今

    美国亚利桑那州立大学

    师资培训

Honors & Awards

No content for now.

A DQN-driven three-stage multi-objective algorithm for whole-process hot rolling steel scheduling

一种由DQN驱动的三阶段多目标算法用于全流程热轧钢调度

2026-06-010
PRE
Radioprotectant-loaded visualizable cationic radioactive microspheres: Reduced hepatic tissue damage and intra/postoperative imaging during TARE
2026-01-290
OAAI
Superparamagnetic iron oxide nanoparticles in clinical applications: current status and future perspectives

超顺磁性氧化铁纳米颗粒的临床应用:现状与未来展望

2025-12-030
OAAI
Dispersion mechanism of sodium dodecylbenzene sulfonate on nanoparticles in TiO2 water based lubricant

十二烷基苯磺酸钠在TiO2水基润滑剂中纳米颗粒上的分散机制

2025-11-270
PRE
Interplay between mercury stress and plant cell response: a phenotypic perspective
2025-10-200
PRE
Prediction of the Assembly Process and Structure of Heteromultimeric Proteins via Multilevel Conformational Merging

通过多层级构象融合预测异源多聚蛋白的装配过程与结构

2025-09-170
PRE
Subcellular distribution of Prussian blue nanozymes dictates enzymatic activity and macrophage polarization for effective colitis therapy

普鲁士蓝纳米酶的亚细胞分布决定了其酶活性及巨噬细胞极化,以实现有效的结肠炎治疗

2025-08-090
PRE
From Rational Design to Druggability Optimization: A Review of Iron-based Nanozymes for Biomedical Applications

从理性设计到成药性优化:铁基纳米酶在生物医学应用中的综述

2025-07-280
PRE
Design and synthesis of a carbonyl–nitrogen multi-resonance thermally activated delayed fluorophore with enhanced charge transfer for electroluminescence application

一种具有增强电荷转移的羰基-氮多共振热激活延迟荧光分子的设计与合成,用于电致发光应用

2025-07-210
PRE
TOUSLED KINASE INTERACTING PROTEIN 1 (TKI1) interacts with SIN3-LIKES (SNLs) to promote flowering in Arabidopsis

拟南芥中凌乱激酶互作蛋白1 (TKI1) 与SIN3-样蛋白 (SNLs) 相互作用以促进开花。

2025-05-010
PRE
Nanoassemblies loaded with low-dose paclitaxel can enhance the response of lung cancer immunotherapy by activating dendritic cells

负载低剂量紫杉醇的纳米组装体可通过激活树突状细胞来增强肺癌免疫疗法的响应。

2025-04-010
OA
Highly Sensitive Temperature Sensing in Biological Region with Ratiometric Fluorescent Response
2025-02-280
OAAI
Oxygen Nanobubbles Enhance ICG/Fe(III)-Mediated Dual-Modal Therapy To Induce Ferroptosis in Tumor Treatment

氧气纳米气泡增强ICG/Fe(III)介导的双模态疗法以诱导肿瘤治疗中的铁死亡

2025-02-180
PRE
A CIA strategy with eminent drug-loading capacities for tumor ferroptosis-gas synergistic therapy
2024-10-280
OAAI
Design of a Multifunctional Nanozyme for Resolving the Proinflammatory Plaque Microenvironment and Attenuating Atherosclerosis (vol 17, pg 14555, 2023)
2024-09-190
PRE
Ultrasmall Prussian Blue Nanozyme Attenuates Osteoarthritis by Scavenging Reactive Oxygen Species and Regulating Macrophage Phenotype

超小普鲁士蓝纳米酶通过清除活性氧和调节巨噬细胞表型减轻骨关节炎

2024-09-031
PRE
Structural basis for linker histone H5-nucleosome binding and chromatin fiber compaction
2024-08-051
OAAI
The synthesis of iron oxide nanoparticles in confined space

受限空间中铁氧化物纳米颗粒的合成

2024-07-121
PRE
Polygenic risk score of metabolic dysfunction-associated steatotic liver disease amplifies the health impact on severe liver disease and metabolism-related outcomes

代谢功能障碍相关脂肪性肝病的多基因风险评分放大了对严重肝病和代谢相关结局的健康影响

2024-07-121
OAAI