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Adam J. Mead

university of oxford

56H-index
381Paper Count
1.3WCitation Count
Published Papers 87
Publication Date
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TRANSFORM-1 Phase 3 study: Efficacy and safety of navitoclax plus ruxolitinib in patients with untreated myelofibrosis
errBlood
IF23.1
err2026-07-02
err0
PREAI
errNaveen Pemmaraju; Adam J. Mead; Tim CP Somervaille; Francesca Palandri; Steffen Koschmieder; Robert Delage; Jean-Jacques Kiladjian; Christopher Benton; Srinivas K. Tantravahi; Noa Lavi; Su-Peng Yeh; Maria Teresa Gomez Casares; Emanuele Ammatuna; Andrew McDonald; Sung-Soo Yoon; Keita Kirito; Timothy Devos; Andrew Perkins; Atanas Radinoff; Omur Gokmen Sevindik
errShare
errSave
The lysine-specific demethylase 1 (LSD1) inhibitor bomedemstat in myelofibrosis: results from a phase 1/2 study
errBlood Advances
IF7.1
err2026-05-02
err0
errOAAI
errHarinder Gill; Abdulraheem Yacoub; Aaron T. Gerds; Jake Shortt; James M. Rossetti; Adam J. Mead; Joachim R Göthert; Steffen Koschmieder; Joanne Ewing; Anna Halpern; Francesca Palandri; Francesco Passamonti; Ruben Mesa; Monia Marchetti; Claire Harrison; Alessandro M. Vannucchi; Justin M. Watts; John C. Wood; David M. Ross; Jennifer Peppe
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errSave
Myeloproliferative neoplasms with concomitant chronic myeloid leukemia are associated with TKI resistance and poor outcomes
errLeukemia
IF13.4
err2026-03-27
err0
errOAAI
errLaura Li Gagnon; Andrea Duminuco; Fabio Stagno; Marta Sobas; Mikhail Fominykh; Andres Virchis; Franck-Emmanuel Nicolini; Julie Hildt; Helen Bentley; Anna L. Godfrey; Lee-Yung Shih; Ashlyn Chee; Adam Mead; Krzysztof Lewandowski; Patryk Sobieralski; Guy Hannah; Yasmin Reyal; Thomas Cummin; Jaroslaw Piszcz; Kawai Yip; Rebecca Frewin; Srinivasan Narayanan; Deborah Rahman; Alero Ajayi; Paul Cervi; Jennifer Byrne; Tom Taylor; Weronika Lebowa; Jiri Pavlu; Siamak Arami; Mansour Ceesay; Dominik Chraniuk; Robert Delage; Annalisa Condorelli; Clémence Santana; Deepti H. Radia; Hugues de Lavallade; Dragana Milojkovic; Claire Harrison; Patrick Harrington
errShare
errSave
Investigation and management of thrombocytosis without JAK2, CALR or MPL mutations: A British Society for Haematology Guideline
errBRITISH JOURNAL OF HAEMATOLOGY
IF3.8
err2025-12-01
err0
errOAAI
errGodfrey, Anna L.; Khan, Alesia A.; McGregor, Andrew; Innes, Andrew J.; Altohami, Mohammed; Cross, Nicholas C. P.; Frewin, Rebecca; Garg, Mamta; Green, Anna; Grinfeld, Jacob; McLornan, Donal P.; Wilson, Andrew J.; Harrison, Claire N.; Mead, Adam J.; Nangalia, Jyoti
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errSave
HIGH PREVALENCE OF GERMLINE PREDISPOSITION IN PAEDIATRIC MYELODYSPLASTIC SYNDROME: A SINGLE-CENTRE RETROSPECTIVE ANALYSIS
errEJC Paediatric Oncology
IF0
err2025-11-01
err0
errOAAI
errNyiro, Judit; Louka, Eleni; Wood, Amy; Rao, Anupama; Rohlfs, Meino; Binder, Vera; Vallee, Tanja; Albert, Michael; Klein, Christoph; Mead, Adam
errShare
errSave
SINGLE CELL PROTEOGENOMIC PROFILING OF TP53 MUTATED MYELODYSPLASTIC NEOPLASMS-ALL CLONES ARE NOT EQUAL
errLEUKEMIA RESEARCH
IF2.2
err2025-09-01
err0
PREAI
errGurashi, Kristian; Wood, Amy; Lukic, Ivan; Sciambi, Adam; Quek, Lynn; Wiseman, Daniel; Mead, Adam; Chowdhury, Onima
errShare
errSave
Platelets sequester extracellular DNA; capturing tumor-derived and free fetal DNA
errScience
IF45.8
err2025-08-14
err0
PREAI
errLauren Murphy; Jeanne Inchauspé; Giampiero Valenzano; Pamela Holland; Nikolaos Sousos; Hayley L. Belnoue-Davis; Rong Li; Natalie J. Jooss; Camelia Benlabiod; Eleanor Murphy; Zohar Etzioni; Emelie Shepherd; Lucy Denly; Sujata Biswas; Lin Chen; Jennifer O’Sullivan; Michael P. Rimmer; Abdullah O. Khan; Christina Simoglou Karali; Nadia Nasreddin; Ian S. Hitchcock; Milka Koupenova; Skirmantas Kriaucionis; Jim R. Hughes; Eric O’Neill; Manu Vatish; Paul Rees; Simon Leedham; Michael Desborough; Adam J. Mead; Benjamin Schuster-Böckler; Christopher D. Gregory; Bethan Psaila
errShare
errSave
Fedratinib combined with ropeginterferon alfa-2b in patients with myelofibrosis (FEDORA): study protocol for a multicentre, open-label, Bayesian phase II trial
errBMC CANCER
IF3.4
err2025-01-10
err0
errOAAI
errMcilroy, Graham; Gaskell, Charlotte; Jackson, Aimee; Yafai, Emily; Tasker, Rachel; Thomas, Catherine; Fox, Sonia; Boucher, Rebecca; Ghebretinsea, Fitsum; Harrison, Claire; Mead, Adam J.; Mcmullin, Mary Frances
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errSave
Molecular pro fil ing in MPN: who should have it and why?
errHEMATOLOGY-AMERICAN SOCIETY OF HEMATOLOGY EDUCATION PROGRAM
IF3.2
err2024-12-06
err1
PREAI
errChee, Ashlyn; Mead, Adam J.
errShare
errSave
Efficacy of a Novel BCL-XL Degrader, DT2216, in Preclinical Models of Post-Myeloproliferative Neoplasm Secondary AML
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errWang, Zhe; Skwarska, Anna; Poigailwar, Gowri; Chaudhry, Sovira; Rodriguez-Meira, Alba; Sui, Pinpin; Olivier, Emmanuel; Jia, Yannan; Ramage, Cassandra L.; Zheng, Guangrong; Schurer, Alexandra; Gritsman, Kira; Papapetrou, Eirini; Bhalla, Kapil N.; Zhou, Daohong; Mead, Adam J.; Rampal, Raajit; Tyner, Jeffrey W.; Abbas, Hussein A.; Pemmaraju, Naveen; Tatarata, Qi Zhang; Konopleva, Marina
errShare
errSave
Spatial Transcriptomics Identifies Aberrant Communication between Dendritic Cells and Leukemia Stem Cells As a Therapeutically Targetable Axis in Juvenile Myelomonocytic Leukemia
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errLouka, Eleni; Gurashi, Kristian; Wen, Sean; Salio, Mariolina; Karali, Christina Simoglou; Doll, Roman; Clark, Sally-Ann; Kosmidou, Anastasia; Cooper, Rosalin; Royston, Daniel; Iskander, Deena; Hayder, Nawshad; Teague, Renuka; Garcia, Cristina Tormo; Greco, Maria; Gutierrez, Paola Vargas; Bull, Joshua; Rao, Anupama; Roberts, Irene; Mead, Adam J.
errShare
errSave
Single-Cell Multiomic Profiling of TP53 Mutated Myelodysplastic Neoplasms- All Clones Are Not Equal
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errChowdhury, Onima; Gurashi, Kristian; Wood, Amy; Lukic, Ivan; Sciambi, Adam; Quek, Lynn; Wiseman, Daniel H.; Mead, Adam J.
errShare
errSave
Interim Analysis of Promise, a Clinical Study Combining the BET Inhibitor OPN-2853 with Ruxolitinib in Patients with Advanced Myelofibrosis Experiencing an Inadequate Response to Ruxolitinib
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errMead, Adam J.; Huntly, Brian J. P.; Psaila, Bethan; Harrison, Claire; Boucher, Rebecca; Wang, Jiayi; Collings, Rebecca; Nagy, Zsofia; Record, Rebecca
errShare
errSave
RUX-AZA Response in AP/BP-MPN Is Driven By Release of the Differentiation Block in Mutant HSPCs: A Single-Cell Multi-Omic Analysis of Responders on the Phase Ib Phazar Study
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errBrierley, Charlotte K.; Gaskell, Charlotte; Harrison, Claire; Yap, Christina; Jackson, Aimee; Byrne, Jennifer; Hamblin, Angela; Clark, Sally-Ann; Sullivan, Jennifer O.; Rodriguez-Meira, Alba; Murphy, Lauren; Clarke, Fiona Jane; Narayanan, Srinivasan; Bowen, David T.; Gudgin, Emma; Milojkovic, Dragana; Collings, Rebecca; Psaila, Bethan; Knapper, Steve; Drummond, Mark W.; Mead, Adam J.
errShare
errSave
Real World Efficacy and Safety of Momelotinib for Myelofibrosis: Evaluation of a UK-Wide Study Confirms 40% Anaemia Response Rate in a Non-Clinical Trial Cohort
errBLOOD
IF23.1
err2024-11-05
err2
PREAI
errRampotas, Alexandros; Torre, Elena; Carter-Brzezinski, Luke; Duminuco, Andrea; Cadman-Davies, Llywelyn; Chee, Ashlyn; Panitsas, Fotios; Alimam, Samah; Milojkovic, Dragana; Kaczmarski, Richard; Fraser, Louise; Frewin, Rebecca; Foley, Kate; Hockings, Catherine; Khan, Alesia; Williams, Rhys; Ryan, Jennifer; Yip, Kawai; Thaw, Kyaw Htin; Sheikh, Amna; Wadelin, Frances; Godfrey, Anna L.; Teh, Chun Huat; Wilson, Andrew J.; Lambert, Jonathan; Mead, Adam J.; Mclornan, Donal P.; Innes, Andrew J.; Mcgregor, Andrew; Somervaille, Tim; Harrison, Claire; Harrington, Patrick; Psaila, Bethan
errShare
errSave
A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2024-10-09
err1
errOAAI
errLi, Rong; Colombo, Michela; Wang, Guanlin; Rodriguez-Romera, Antonio; Benlabiod, Camelia; Jooss, Natalie J.; O'Sullivan, Jennifer; Brierley, Charlotte K.; Clark, Sally-Ann; Saez, Juan M. Perez; Fernandez, Pedro Aragon; Schoof, Erwin M.; Porse, Bo; Meng, Yiran; Khan, Abdullah O.; Wen, Sean; Dong, Pengwei; Zhou, Wenjiang; Sousos, Nikolaos; Murphy, Lauren; Clarke, Matthew; Olijnik, Aude-Anais; Wong, Zoe C.; Karali, Christina Simoglou; Sirinukunwattana, Korsuk; Ryou, Hosuk; Norfo, Ruggiero; Cheng, Qian; Carrelha, Joana; Ren, Zemin; Thongjuea, Supat; Rathinam, Vijay A.; Krishnan, Anandi; Royston, Daniel; Rabinovich, Gabriel A.; Mead, Adam J.; Psaila, Bethan
errShare
errSave
Treatment of the blood cancer polycythemia vera with ruxolitinib in the MAJIC-PV study: a plain language summary
errFUTURE ONCOLOGY
IF2.6
err2024-10-01
err1
errOAAI
errHarrison, Claire N.; Fox, Sonia; Boucher, Rebecca; McMullin, Mary Frances; Mead, Adam J.
errShare
errSave
Safety and efficacy of luspatercept for the treatment of anemia in patients with myelofibrosis
errBLOOD ADVANCES
IF7.1
err2024-08-28
err9
errOAAI
errGerds, Aaron T.; Harrison, Claire; Kiladjian, Jean-Jacques; Mesa, Ruben; Vannucchi, Alessandro M.; Komrokji, Rami; Bose, Prithviraj; Kremyanskaya, Marina; Mead, Adam J.; Gotlib, Jason; Rose, Shelonitda; Sanabria, Fabian; Marsousi, Niloufar; Giuseppi, Ana Carolina; Jiang, Huijing; Palmer, Jeanne M.; McCaul, Kelly; Ribrag, Vincent; Passamonti, Francesco
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errSave
Predictive Performance of Cardiovascular Risk Scores in Cancer Survivors From the UK Biobank
errJACC: CARDIOONCOLOGY
IF12.8
err2024-08-01
err0
errOAAI
errMcCracken, Celeste; Condurache, Dorina-Gabriela; Szabo, Liliana; Elghazaly, Hussein; Walter, Fiona M.; Mead, Adam J.; Chakraverty, Ronjon; Harvey, Nicholas C.; Manisty, Charlotte H.; Petersen, Steffen E.; Neubauer, Stefan; Raisi-Estabragh, Zahra
errShare
errSave
Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells
errNATURE IMMUNOLOGY
IF27.6
err2024-05-30
err4
errOAAI
errCarrelha, Joana; Mazzi, Stefania; Winroth, Axel; Hagemann-Jensen, Michael; Ziegenhain, Christoph; Hogstrand, Kari; Seki, Masafumi; Brennan, Margs S.; Lehander, Madeleine; Wu, Bishan; Meng, Yiran; Markljung, Ellen; Norfo, Ruggiero; Ishida, Hisashi; Stralin, Karin Belander; Grasso, Francesca; Karali, Christina Simoglou; Aliouat, Affaf; Hillen, Amy; Chari, Edwin; Siletti, Kimberly; Thongjuea, Supat; Mead, Adam J.; Linnarsson, Sten; Nerlov, Claus; Sandberg, Rickard; Yoshizato, Tetsuichi; Woll, Petter S.; Jacobsen, Sten Eirik W.
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errSave

Research Directions

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