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D

David Malkin

The Hospital for Sick Children

86H-index
776Paper Count
3.2WCitation Count
Published Papers 180
Publication Date
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Prior therapy defines mutation profiles in childhood cancer at relapse
errNature
IF48.5
err2026-07-22
err0
errOAAI
errMehdi Layeghifard; Marcos Díaz-Gay; Erik N. Bergstrom; Mathepan J. Mahendralingam; Nicholas Light; Sasha Blay; Joshua O. Nash; Nathaniel D. Anderson; Jessica N. Au; Scott Davidson; Pedro L. Ballester; Timmy Wen; Syed Kashif Daud; Lisa-Monique Edward; S. M. Ashiqul Islam; Azhar Khandekar; Burçak Otlu; Ledia Brunga; Rawan Hammad; Shimaa Nassif; Nirav H. Thacker; Tara Feltham; Noemi A. Fuentes-Bolanos; Marie Wong-Erasmus; Max F. Levine; Katherine E. Miller; Neerav N. Shukla; Michael D. Kinnaman; Dominik Glodzik; Carol Portwine; Sabrina Millson; Alexandra P. Zorzi; Mariam Mikhail; Conrad V. Fernandez; Laura Wheaton; Gunes Gundem; Andrew L. Kung; Uri Tabori; Chelsea Mayoh; Elli Papaemmanuil; Mark J. Cowley; David Malkin; Anita Villani; Ludmil B. Alexandrov; Adam Shlien
errShare
errSave
Non-invasive screening in hereditary cancer: a randomized controlled trial to test cell-free DNA-based early detection in the CHARM consortium
errEuropean Journal of Human Genetics
IF4.6
err2026-01-29
err0
errOAAI
errKirsten M. Farncombe; Julia A. Sobotka; Melyssa Aronson; Mark Basik; Yvonne Bombard; Leslie Born; Rona Cheifetz; Marc Clausen; Natalie Coburn; Lesa Dawson; Andrea S. Doria; Khaled Y. Elbanna; Holly Etchegary; William D. Foulkes; Chiquita Hessels; Angela Hyde; Karineh Kazazian; Adam Kinnaird; C. Anne Koch; Stephane Laframboise; Jordan Lerner-Ellis; Stephanie Lheureux; David Malkin; Ur Metser; Lynette S. Penney; Sarah Ridd; Kasmintan A. Schrader; Teresa Tiano; Alicia A. Tone; Patrick Veit-Haibach; Stephanie Wong; Wei Xu; Trevor J. Pugh; Raymond H. Kim
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errSave
Patterns of hypermutation shape tumorigenesis and immunotherapy response in mismatch-repair-deficient glioma
errNature Genetics
IF29
err2025-12-22
err0
PREAI
errNicholas R. Fernandez; Yuan Chang; Nuno M. Nunes; Jose R. Dimayacyac; Adrian Levine; Amit Ringel; Logine Negm; Ayse Bahar Ercan; Julian M. Hess; Olfat Ahmad; Caitlin Lee; Lucie Stengs; Vanessa Bianchi; Melissa Edwards; Sheradan Doherty; Jiil Chung; Liana Nobre; Julie Bennett; Andrew J. Dodgshun; David T. W. Jones; Stefan M. Pfister; Anita Villani; David Malkin; Vijay Ramaswamy; Annie Huang; Eric Bouffet; Melyssa Aronson; Peter B. Dirks; Adam Shlien; Gad Getz; Yosef E. Maruvka; Birgit Ertl-Wagner; Cynthia Hawkins; Anirban Das; Uri Tabori
errShare
errSave
The legacy of a gentleman scientist: Pierre Hainaut
errCell Death & Differentiation
IF0
err2025-10-03
err0
errOAAI
errChristophe Arnoult; Laura D. Attardi; Kerem Batsheva; Giovanni Blandino; Kathleen H. Burns; Giannino Del Sal; David G. Kirsch; David P. Lane; Arnold J. Levine; Guillermina Lozano; David Malkin; Gerry Melino; Moshe Oren; Carol Prives; Daniel Schramek
errShare
errSave
The argument for screening programs in previvors with Li-Fraumeni syndrome
errExpert Review of Anticancer Therapy
IF2.8
err2025-07-03
err0
PREAI
errMeis Omran; David Malkin
errShare
errSave
Genetic predisposition in sarcomas: clinical implications and management
errECLINICALMEDICINE
IF10
err2025-05-01
err0
PREAI
errConnolly, Elizabeth A.; Boye, Kjetil; Bonvalot, Sylvie; Kratz, Christian P.; Leithner, Andreas; Malkin, David; Messiou, Christina; Miah, Aisha B.; Pantziarka, Pan; Timmermann, Beate; van der Graaf, Winette T. A.; Thomas, David M.; Stacchiotti, Silvia
errShare
errSave
Limiting surveillance in individuals with the Palestinian TP53 p. R181C founder variant-is it too soon to draw conclusions?
errJNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
IF7.2
err2025-02-06
err0
PREAI
errOmran, Meis; Malkin, David
errShare
errSave
High detection rate of circulating-tumor DNA from cerebrospinal fluid of children with central nervous system germ cell tumors
errACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
err2024-11-20
err0
errOAAI
errNakano, Yoshiko; Burns, Ian; Nobre, Liana; Siddaway, Robert; Rana, Mansuba; Nesvick, Cody; Bondoc, Andrew; Ku, Michelle; Yuditskiy, Richard; Ku, Dennis T. L.; Shing, Matthew M. K.; Cheng, Kevin K. F.; Ng, Ho-Keung; Das, Anirban; Bennett, Julie; Ramaswamy, Vijay; Huang, Annie; Malkin, David; Ertl-Wagner, Birgit; Dirks, Peter; Bouffet, Eric; Bartels, Ute; Tabori, Uri; Hawkins, Cynthia; Liu, Anthony P. Y.
errShare
errSave
Characterisation of Paediatric Neuroblastic Tumours by Quantitative Structural and Diffusion-Weighted MRI
errJOURNAL OF CLINICAL MEDICINE
IF2.9
err2024-11-06
err0
errOAAI
errTambasco, Domenica; Zlotnik, Margalit; Joshi, Sayali; Moineddin, Rahim; Harris, Shelley; Villani, Anita; Malkin, David; Morgenstern, Daniel A.; Doria, Andrea S.
errShare
errSave
International policies guiding the selection, analysis, and clinical management of secondary findings from genomic sequencing: A systematic review
errAMERICAN JOURNAL OF HUMAN GENETICS
IF8.1
err2024-10-01
err1
PREAI
errMajeed, Safa; Johnston, Christine; Saeedi, Saumeh; Mighton, Chloe; Rokoszak, Vanessa; Abbasi, Ilham; Grewal, Sonya; Aguda, Vernie; Kissoondoyal, Ashby; Malkin, David; Bombard, Yvonne
errShare
errSave
Characterization of circulating tumor DNA in a pediatric oncology cohort and implementation into the SickKids Cancer Sequencing (KiCS) precision oncology program
errCANCER RESEARCH
IF16.6
err2024-09-05
err0
PREAI
errCohen-Gogo, Sarah; Choi, Taegi; Ripsman, Ryan; Hudson, Matt; Fong, Sandy; Khan, Reem; Venier, Rosemarie E.; Charlinski, Tristan; Villani, Anita; Malkin, David; Shlien, Adam
errShare
errSave
High-risk pediatric cancer models in zebrafish, mouse and short-term culture predict individual patient responses to therapy
errCANCER RESEARCH
IF16.6
err2024-09-05
err0
PREAI
errAzzam, Nadine; Fletcher, Jamie I.; Melong, Nicole; Lau, Loretta; Dolman, Emmy M.; Mao, Jie; Tax, Gabor; Cadiz, Roxanne; Tuzi, Lissandra; Kamili, Alvin; Dumevska, Biljana; Xie, Jinhan; Chan, Jennifer A.; Senger, Donna L.; Grover, Stephanie A.; Malkin, David; Haber, Michelle; Berman, Jason N.
errShare
errSave
Establishment of the consortium for childhood cancer predisposition and the childhood cancer predisposition study
errCANCER RESEARCH
IF16.6
err2024-09-05
err0
PREAI
errPorter, Christopher C.; Brodeur, Garrett M.; Diller, Lisa; Edgerton, Chloe; Kamihara, Junne; Kohlmann, Wendy; MacFarland, Suzanne P.; Maese, Luke; Malkin, David; Nichols, Kim E.; Perrino, Melissa R.; Plon, Sharon E.; Rednam, Surya; Villani, Anita
errShare
errSave
Timing the development of chemoresistance in relapsed pediatric cancer with mutational signatures
errCANCER RESEARCH
IF16.6
err2024-09-05
err0
PREAI
errBlay, Sasha; Layeghifard, Mehdi; Davidson, Scott; Chen, David; Schwertschkow, Astra; Ramaswamy, Vijay; Taylor, Michael; Papaemmanuil, Elli; Villani, Anita; Malkin, David; Alexandrov, Ludmil; Cowley, Mark; Shlien, Adam
errShare
errSave
ACCESS: Advancing childhood cancer experience, science and survivorship in Canada
errCANCER RESEARCH
IF16.6
err2024-09-05
err0
PREAI
errGrover, Stephanie A.; Williams, Christine J.; Co-Dyre, Adrienne; Malkin, David; Whitlock, James A.
errShare
errSave
TP53 variant clusters stratify the Li-Fraumeni spectrum and reveal an osteosarcoma-prone subgroup
errCANCER RESEARCH
IF16.6
err2024-09-05
err0
PREAI
errFischer, Nicholas W.; Laverty, Brianne; Alon, Noa; Montellier, Emilie; Hainaut, Pierre; Maxwell, Kara N.; Kratz, Christian P.; Malkin, David
errShare
errSave
Risk of therapy-related subsequent cancers in individuals with germline TP53 variants
errCANCER RESEARCH
IF16.6
err2024-09-05
err0
PREAI
errVillani, Anita; Khincha, Payal; Hatton, Jessica; Schonfeld, Sara; Goudie, Catherine; Oba, Leatrisse; Pithadia, Kishan; Sanger, Birte; Kratz, Christian; Le, Anh N.; Orr, Caitlin; Maxwell, Kara N.; Naumer, Anne; Vagher, Jennie; Kohlmann, Wendy; Schi, Joshua; dos Santos, Elizabeth Santana; Michaeli, Orli; Carson, Jacob J.; Tsang, Derek S.; Kim, Raymond; Maciaszek, Jamie L.; Nichols, Kim E.; Goodman, Victoria E.; MacFarland, Suzanne P.; Reichman, Lara; Achatz, Maria Isabel; Savage, Sharon; Malkin, David; Morton, Lindsay M.
errShare
errSave
Exploring the role of microbiota in cancer development in Li-Fraumeni Syndrome
errCANCER RESEARCH
IF16.6
err2024-09-05
err0
PREAI
errOng, Noel W. Y.; Giovino, Camilla M.; Fischer, Nicholas W.; Psarianos, Pamela; Malkin, David
errShare
errSave
Single cell transcriptomic signature of Li-Fraumeni Syndrome soft tissue sarcomas
errCANCER RESEARCH
IF16.6
err2024-09-05
err0
PREAI
errKissoondoyal, Ashby; Malkin, David
errShare
errSave
Value of Engagement in Digital Health Technology Research:Evidence Across 6 Unique Cohort Studies
errJOURNAL OF MEDICAL INTERNET RESEARCH
IF6
err2024-09-03
err0
errOAAI
errGoodday, Sarah M.; Karlin, Emma; Brooks, Alexa; Chapman, Carol; Harry, Christiana; Lugo, Nelly; Peabody, Shannon; Rangwala, Shazia; Swanson, Ella; Tempero, Jonell; Yang, Robin; Karlin, Daniel R.; Rabinowicz, Ron; Malkin, David; Travis, Simon; Walsh, Alissa; Hirten, Robert P.; Sands, Bruce E.; Bettegowda, Chetan; Holdhoff, Matthias; Wollet, Jessica; Szajna, Kelly; Dirmeyer, Kallan; Dodd, Anna; Hutchinson, Shawn; Ramotar, Stephanie; Grant, Robert C.; Boch, Adrien; Wildma, Mackenzie; Friend, Stephen H.
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Carlo M. Croce
H-index: 209 · Papers: 1.8K
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Steven J.M. Jones
H-index: 189 · Papers: 1.3K
T
Tak W. Mak
H-index: 181 · Papers: 1.6K
S
Stephen J. Chanock
H-index: 170 · Papers: 2.2K
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