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Louis G. Smith

University of Pennsylvania
H-index:7
Citation Count:186
Views:0

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SGLT2 inhibitors activate pantothenate kinase in the human heart

SGLT2抑制剂在人类心脏中激活泛酸激酶

Science
IF45.8
2026-08-270
PRE
Nicholas Forelli; Trace Thome; Deborah M. Eaton; Kollin Schultz; Jiten Patel; Caitlyn E. Bowman; Ryo Kawakami; Jae Woo Jung; Ivan A. Kuznetsov; Kristina Li; Jialiu A. Liang; Kirsten Branch; Claire Brady; Kenneth C. Bedi; Yijun Yang; Kaustubh Koya; Nesrine Bouhrira; Emily Megill; Daniel S. Kantner; Louis G. Smith; Cristin F. MacIntosh; Kushol Gupta; Gregory R. Bowman; Nathaniel W. Snyder; Jonathan Edwards; Kenneth B. Margulies; Zoltan Arany
RNP interfaces as regulatory “active sites”: a repurposing strategy for small molecules targeting viral 5′-untranslated regions

核糖核蛋白界面作为调节性“活性位点”：靶向病毒5′-非翻译区的小分子再利用策略

Frontiers in Molecular Biosciences
IF4
2026-05-280
OAAI
LG Louis G. Smith †; SA Solomon Attionu †; SM Sudeshi M. Abedeera; BH Barrington Henry; SP Srinivasa Penumutchu; BS Blanton S. Tolbert
PopShift: A Thermodynamically Sound Approach to Estimate Binding Free Energies by Accounting for Ligand-Induced Population Shifts from a Ligand-Free Markov State Model
JOURNAL OF CHEMICAL THEORY AND COMPUTATION
IF5.5
2024-01-313
OAAI
Smith, Louis G.; Novak, Borna; Osato, Meghan; Mobley, David L.; Bowman, Gregory R.
Apolipoprotein E4 has extensive conformational heterogeneity in lipid-free and lipid-bound forms
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2023-02-0716
OAAI
Stuchell-Brereton, Melissa D.; Zimmerman, Maxwell I.; Miller, Justin J.; Mallimadugula, Upasana L.; Incicco, J. Jeremias; Roy, Debjit; Smith, Louis G.; Cubuk, Jasmine; Baban, Berevan; DeKoster, Gregory T.; Frieden, Carl; Bowman, Gregory R.; Soranno, Andrea
Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains
ELIFE
IF0
2023-01-2715
OA
Meller, Artur; Lotthammer, Jeffrey M.; Smith, Louis G.; Novak, Borna; Lee, Lindsey A.; Kuhn, Catherine C.; Greenberg, Lina; Leinwand, Leslie A.; Greenberg, Michael J.; Bowman, Gregory R.
Developing an Accurate All-Atom Fixed-Charge Force Field for RNA with Implicitly Polarized Charges
BIOPHYSICAL JOURNAL
IF3.1
2019-02-010
OAAI
Cavender, Chapin E.; Smith, Louis G.; Grossfield, Alan; Mathews, David H.
Exploring Hydrogen Bond Geometry in RNA with F-SAPT
BIOPHYSICAL JOURNAL
IF3.1
2019-02-010
OAAI
Smith, Louis G.; Cavender, Chapin E.; Grossfield, Alan; Mathews, David H.
Chemically Accurate Relative Folding Stability of RNA Hairpins from Molecular Simulations
JOURNAL OF CHEMICAL THEORY AND COMPUTATION
IF5.5
2018-10-3014
OA
Smith, Louis G.; Tan, Zhen; Spasic, Aleksandar; Dutta, Debapratim; Salas-Estrada, Leslie A.; Grossfield, Alan; Mathews, David H.
Benchmarking RNA Force Fields using Hairpin Loop Folding Free Energy Change
BIOPHYSICAL JOURNAL
IF3.1
2018-02-010
OAAI
Smith, Louis G.; Tan, Zhen; Spasic, Aleksandar; Grossfield, Alan; Mathews, David H.
Physics-based all-atom modeling of RNA energetics and structure
WILEY INTERDISCIPLINARY REVIEWS-RNA
IF4.8
2017-08-1729
OAAI
Smith, Louis G.; Zhao, Jianbo; Mathews, David H.; Turner, Douglas H.
Toward a Beautiful Amalgam: The Necessity of Heterogeneity in RNA Science and Research Culture

走向美丽的融合：异质性在RNA科学与研究文化中的必要性

ACS Bio & Med Chem Au
IF4.3
0
OA
Sudeshi M. Abedeera; Mary Donnelly; James Hagerty; Shaila Kolli; Srinivasa R. Penumutchu; Louis G. Smith; Blanton S. Tolbert

Research Directions

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D
David H. Mathews
H-index:55Papers:286Citations:2.1万
G
Gregory R. Bowman
H-index:58Papers:211Citations:1.1万
A
Alan Grossfield
H-index:37Papers:228Citations:5,041
C
Chapin E. Cavender
H-index:7Papers:31Citations:261
Z
Zhen Tan
H-index:9Papers:16Citations:807
A
Aleksandar Spasic
H-index:11Papers:38Citations:534
S
Sudeshi M. Abedeera
H-index:3Papers:10Citations:20
B
Borna Novak
H-index:10Papers:24Citations:368
J
Jae Woo Jung
H-index:16Papers:45Citations:713
T
Trace Thome
H-index:14Papers:50Citations:606