Mario J. Borgnia - Publications, H-index & Citations

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Mario J. Borgnia

research triangle park

48H-index

204Paper Count

1.1WCitation Count

Published Papers 89

Publication Date

Molecular basis for cold and menthol sensing by mammalian TRPM8

Nature Communications

IF15.7

2026-08-17

OAAI

Hyuk-Joon Lee; Cheon-Gyu Park; Justin G. Fedor; Wyatt A. Peele; Mario J. Borgnia; Seok-Yong Lee

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Lipid-manager autophagy proteins ATG2 and ATG9 regulate extracellular vesicle secretion via amphisome biogenesis and cell lipidome modulation

Nature Communications

IF15.7

2026-07-22

OAAI

Asmita Singh; Dylan J. Johnson; Jeffrey Kuhn; Katina L. Johnson; Jason G. Williams; Ricardo Vancini; Deloris Sutton; Kedar Sharma; Jadranka Loncarek; Mario J. Borgnia; Carlos M. Guardia

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Structural basis of fungal β-1,3-glucan synthase inhibition by caspofungin

Nature

IF48.5

2026-04-22

OAAI

Zhenning Ren; Abhishek Chhetri; Chang Liu; ShuYu Offner; Kedar Sharma; Mario J. Borgnia; Wonpil Im; Kenichi Yokoyama; Seok-Yong Lee

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Advances in automation for cryo-electron tomography data collection

Current Opinion in Structural Biology

IF7

2025-11-24

PREAI

Kedar Sharma; Mario J. Borgnia

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Self-Tuning Workflow for Automated Cryo-EM Data Collection in SmartScope

Microscopy and Microanalysis

IF3

2025-07-25

PREAI

Jonathan Bouvette; Laura He; Karunakar R Pothula; Mario J Borgnia; Alberto Bartesaghi

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Cryo-EM structures of engineered Shiga toxin-based immunogens capable of eliciting neutralizing antibodies with therapeutic potential against hemolytic uremic syndrome

PROTEIN SCIENCE

IF5.2

2025-05-24

PREAI

Cristofalo, Alejandro Ezequiel; Sharma, Arvind; Cerutti, Maria Laura; Sharma, Kedar; Melero, Roberto; Pardo, Romina; Goldbaum, Fernando Alberto; Borgnia, Mario; Zylberman, Vanesa; Otero, Lisandro Horacio

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Spontaneous base flipping helps drive Nsp15's preferences in double stranded RNA substrates

NATURE COMMUNICATIONS

IF15.7

2025-01-04

OAAI

Wright, Zoe M.; Butay, Kevin John; Krahn, Juno M.; Wilson, Isha M.; Gabel, Scott A.; Derose, Eugene F.; Hissein, Israa S.; Williams, Jason G.; Borgnia, Mario J.; Frazier, Meredith N.; Mueller, Geoffrey A.; Stanley, Robin E.

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A higher order PUF complex is central to regulation of C. elegans germline stem cells

NATURE COMMUNICATIONS

IF15.7

2025-01-02

OAAI

Qiu, Chen; Crittenden, Sarah L.; Carrick, Brian H.; Dillard, Lucas B.; Dos Santos, Stephany J. Costa; Dandey, Venkata P.; Dutcher, Robert C.; Viverette, Elizabeth G.; Wine, Robert N.; Woodworth, Jennifer; Campbell, Zachary T.; Wickens, Marvin; Borgnia, Mario J.; Kimble, Judith; Hall, Traci M. Tanaka

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Structures of ATP-binding cassette transporter ABCC1 reveal the molecular basis of cyclic dinucleotide cGAMP export

IMMUNITY

IF26.3

2025-01-01

PREAI

Shinde, Omkar; Boyer, Joshua A.; Cambier, Stephanie; Vanportfliet, Jordyn J.; Sui, Xuewu; Yadav, Gaya P.; Viverette, Elizabeth G.; Borgnia, Mario J.; West, A. Phillip; Zhang, Qi; Stetson, Daniel B.; Li, Pingwei

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Mouse α-synuclein fibrils are structurally and functionally distinct from human fibrils associated with Lewy body diseases

SCIENCE ADVANCES

IF12.5

2024-11-01

OAAI

Sokratian, Arpine; Zhou, Ye; Tatli, Meltem; Burbidge, Kevin J.; Xu, Enquan; Viverette, Elizabeth; Donzelli, Sonia; Duda, Addison M.; Yuan, Yuan; Li, Huizhong; Strader, Samuel; Patel, Nirali; Shiell, Lauren; Malankhanova, Tuyana; Chen, Olivia; Mazzulli, Joseph R.; Perera, Lalith; Stahlberg, Henning; Borgnia, Mario; Bartesaghi, Alberto; Lashuel, Hilal A.; West, Andrew B.

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Structures of the mitochondrial single-stranded DNA binding protein with DNA and DNA polymerase γ

NUCLEIC ACIDS RESEARCH

IF13.1

2024-08-06

OAAI

Riccio, Amanda A.; Bouvette, Jonathan; Pedersen, Lars C.; Somai, Shruti; Dutcher, Robert C.; Borgnia, Mario J.; Copeland, William C.

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Coordinated DNA polymerization by Polγ and the region of LonP1 regulated proteolysis

NUCLEIC ACIDS RESEARCH

IF13.1

2024-06-27

OAAI

Riccio, Amanda A.; Brannon, Asia J.; Krahn, Juno M.; Bouvette, Jonathan; Williams, Jason G.; Borgnia, Mario J.; Copeland, William C.

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Structural and Functional Analysis of Heparosan Synthase 2 from Pasteurella multocida to Improve the Synthesis of Heparin

ACS CATALYSIS

IF13.1

2024-04-15

PREAI

Stancanelli, Eduardo; Krahn, Juno A.; Viverette, Elizabeth; Dutcher, Robert; Pagadala, Vijayakanth; Borgnia, Mario J.; Liu, Jian; Pedersen, Lars C.

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Antiviral drug recognition and elevator-type transport motions of CNT3

NATURE CHEMICAL BIOLOGY

IF13.7

2024-02-28

PREAI

Wright, Nicholas J.; Zhang, Feng; Suo, Yang; Kong, Lingyang; Yin, Ying; Fedor, Justin G.; Sharma, Kedar; Borgnia, Mario J.; Im, Wonpil; Lee, Seok-Yong

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Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2024-01-09

OAAI

Hayne, Cassandra K.; Butay, Kevin John U.; Stewart, Zachary D.; Krahn, Juno M.; Perera, Lalith; Williams, Jason G.; Petrovitch, Robert M.; Deterding, Leesa J.; Matera, A. Gregory; Borgnia, Mario J.; Stanley, Robin E.

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Sen1 architecture: RNA-DNA hybrid resolution , autoregulation, and insights into SETX inactivation in AOA2

MOLECULAR CELL

IF16.6

2023-10-01

PREAI

Appel, C. Denise; Bermek, Oya; Dandey, Venkata P.; Wood, Makayla; Viverette, Elizabeth; Williams, Jason G.; Bouvette, Jonathan; Riccio, Amanda A.; Krahn, Juno M.; Borgnia, Mario J.; Williams, R. Scott

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Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2023-06-08

PREAI

Suo, Yang; Wright, Nicholas J.; Guterres, Hugo; Fedor, Justin G.; Butay, Kevin John; Borgnia, Mario J.; Im, Wonpil; Lee, Seok-Yong

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Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2023-05-25

OAAI

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Structure and dynamics of the Arabidopsis O-fucosyltransferase SPINDLY

NATURE COMMUNICATIONS

IF15.7

2023-03-20

OAAI

Kumar, Shivesh; Wang, Yan; Zhou, Ye; Dillard, Lucas; Li, Fay-Wei; Sciandra, Carly A.; Sui, Ning; Zentella, Rodolfo; Zahn, Emily; Shabanowitz, Jeffrey; Hunt, Donald F.; Borgnia, Mario J.; Bartesaghi, Alberto; Sun, Tai-ping; Zhou, Pei

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Cryo-EM reveals the architecture of the PELP1-WDR18 molecular scaffold

NATURE COMMUNICATIONS

IF15.7

2022-11-09

OAAI

Gordon, Jacob; Chapus, Fleur L.; Viverette, Elizabeth G.; Williams, Jason G.; Deterding, Leesa J.; Krahn, Juno M.; Borgnia, Mario J.; Rodriguez, Joseph; Warren, Alan J.; Stanley, Robin E.

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Research Directions