Dale A. Ramsden - Publications, H-index & Citations

Back

Dale A. Ramsden

university of north carolina

51H-index

193Paper Count

1.0WCitation Count

Published Papers 71

Publication Date

Polymerase θ-what does it see, and why does it matter for cancer therapy?

NAR CANCER

IF3.2

2025-12-01

PREAI

Ramsden, Dale A.; Gupta, Gaorav P.

Save

Nonhomologous end-joining uses distinct mechanisms to repair each strand of a double strand break

Nature Communications

IF15.7

2025-11-24

OAAI

Adam J. Luthman; Kishore K. Chiruvella; Andrea M. Kaminski; Thomas A. Kunkel; Lars C. Pedersen; Dale A. Ramsden

Save

Distinctive molecular features of radiation-induced thyroid cancers

Science Advances

IF12.5

2025-08-22

OAAI

Danielle M. Karyadi; Tetiana I. Bogdanova; Cato M. Milder; Stephen W. Hartley; Olivia W. Lee; Michael Dean; Vladimir Drozdovitch; Elizabeth K. Cahoon; Sergii Masiuk; Mykola Chepurny; Liudmyla Yu Zurnadzhy; Vibha Vij; Cari M. Kitahara; Gerry A. Thomas; Gayle E. Woloschak; Dale A. Ramsden; Mykola D. Tronko; Stephen J. Chanock; Lindsay M. Morton

Save

Engineered Cas9 variants bypass Keap1-mediated degradation in human cells and enhance epigenome editing efficiency

NUCLEIC ACIDS RESEARCH

IF13.1

2024-09-04

OAAI

Chen, Jianfeng; Su, Siyuan; Pickar-Oliver, Adrian; Chiarella, Anna M.; Hahn, Quentin; Goldfarb, Dennis; Cloer, Erica W.; Small, George W.; Sivashankar, Smaran; Ramsden, Dale A.; Major, Michael B.; Hathaway, Nathaniel A.; Gersbach, Charles A.; Liu, Pengda

Save

DNA polymerase λ Loop1 variant yields unexpected gain-of-function capabilities in nonhomologous end-joining

DNA REPAIR

IF2.7

2024-04-01

OAAI

Kaminski, Andrea M.; Chiruvella, Kishore K.; Ramsden, Dale A.; Bebenek, Katarzyna; Kunkel, Thomas A.; Pedersen, Lars C.

Save

Sequential requirements for distinct Polq q domains during theta-mediated end joining

MOLECULAR CELL

IF16.6

2024-04-01

PREAI

Fijen, Carel; Beckham, Lea Drogalis; Terino, Dante; Li, Yuzhen; Ramsden, Dale A.; Wood, Richard D.; Doublie, Sylvie; Rothenberg, Eli

Save

Polymerase Mu is a DNA-directed DNA/RNA polymerase

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

156

OAAI

McElhinny, SAN; Ramsden, DA

Save

Ku recruits the XRCC4-ligase IV complex to DNA ends

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

406

OAAI

McElhinny, SAN; Snowden, CM; McCarville, J; Ramsden, DA

Save

Association of DNA polymerase μ (pol μ) with Ku and ligase IV:: Role for pol μ in end-joining double-strand break repair

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

294

OAAI

Mahajan, KN; McElhinny, SAN; Mitchell, BS; Ramsden, DA

Save

Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

332

OAAI

Ding, Q; Reddy, YVR; Wang, W; Woods, T; Douglas, P; Ramsden, DA; Lees-Miller, SP; Meek, K

Save

Poly(ADP) ribose polymerase promotes DNA polymerase theta-mediated end joining by activation of end resection

NATURE COMMUNICATIONS

IF15.7

2022-08-04

OAAI

Luedeman, Megan E.; Stroik, Susanna; Feng, Wanjuan; Luthman, Adam J.; Gupta, Gaorav P.; Ramsden, Dale A.

Save

Analysis of diverse double-strand break synapsis with Polλ reveals basis for unique substrate specificity in nonhomologous end-joining

NATURE COMMUNICATIONS

IF15.7

2022-07-01

OAAI

Kaminski, Andrea M.; Chiruvella, Kishore K.; Ramsden, Dale A.; Bebenek, Katarzyna; Kunkel, Thomas A.; Pedersen, Lars C.

Save

Mechanism, cellular functions and cancer roles of polymerase-theta-mediated DNA end joining

NATURE REVIEWS MOLECULAR CELL BIOLOGY

IF90.2

2021-09-14

110

PREAI

Ramsden, Dale A.; Carvajal-Garcia, Juan; Gupta, Gaorav P.

Save

Mechanisms driving chromosomal translocations: lost in time and space

ONCOGENE

IF7.3

2021-06-08

OAAI

Ramsden, Dale A.; Nussenzweig, Andre

Save

Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks

NUCLEIC ACIDS RESEARCH

IF13.1

2021-05-08

OAAI

Feng, Wanjuan; Simpson, Dennis A.; Cho, Jang-Eun; Carvajal-Garcia, Juan; Smith, Chelsea M.; Headley, Kathryn M.; Hathaway, Nate; Ramsden, Dale A.; Gupta, Gaorav P.

Save

DNA polymerase theta suppresses mitotic crossing over

PLOS GENETICS

IF3.7

2021-03-22

OAAI

Carvajal-Garcia, Juan; Crown, K. Nicole; Ramsden, Dale A.; Sekelsky, Jeff

Save

Dual inhibition of DNA-PK and DNA polymerase theta overcomes radiation resistance induced by p53 deficiency

NAR CANCER

IF3.2

2020-12-21

OAAI

Kumar, Rashmi J.; Chao, Hui Xiao; Simpson, Dennis A.; Feng, Wanjuan; Cho, Min-Guk; Roberts, Victoria R.; Sullivan, Aurora R.; Shah, Sonam J.; Wozny, Anne-Sophie; Fagan-Solis, Katerina; Kumar, Sunil; Luthman, Adam; Ramsden, Dale A.; Purvis, Jeremy E.; Gupta, Gaorav P.

Save

The molecular basis and disease relevance of non-homologous DNA end joining

NATURE REVIEWS MOLECULAR CELL BIOLOGY

IF90.2

2020-10-19

241

OAAI

Zhao, Bailin; Rothenberg, Eli; Ramsden, Dale A.; Lieber, Michael R.

Save

Structural snapshots of human DNA polymerase μ engaged on a DNA double-strand break

NATURE COMMUNICATIONS

IF15.7

2020-09-22

OAAI

Kaminski, Andrea M.; Pryor, John M.; Ramsden, Dale A.; Kunkel, Thomas A.; Pedersen, Lars C.; Bebenek, Katarzyna

Save

Mechanistic basis for microhomology identification and genome scarring by polymerase theta

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-03-31

115

OAAI

Carvajal-Garcia, Juan; Cho, Jang-Eun; Carvajal-Garcia, Pablo; Feng, Wanjuan; Wood, Richard D.; Sekelsky, Jeff; Gupta, Gaorav P.; Roberts, Steven A.; Ramsden, Dale A.

Save

Research Directions