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M

Mien‐Chie Hung

China Medical University Hospital

163H-index
1.5KPaper Count
10.0WCitation Count
Published Papers 534
Publication Date
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CAF-derived PAI-1 serves as an EGFR ligand and fuels KRAS-mutant pancreatic cancer
errNature Communications
IF15.7
err2026-07-04
err0
errOAAI
errYu Wang; Chao Liu; Song Gao; Bo Wang; Hongwei Wang; Zijian Shi; Shunjin Xia; Jiayong Li; Xiaofeng Yao; Xiaofan Guo; Jianwei Zheng; Qianqian Zhou; Zhiqiang Chen; Lei Zheng; Qiang Zhang; Jiang Du; Tianxing Zhou; Zhaoyu Zhang; Weijie Song; Lisha Qi; Yalei Wang; Yuh-Pyng Sher; Min Li; Xuan Zhou; Mien-Chie Hung; Yu Ren; Jihui Hao
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All-trans retinoic acid destabilizes ADAR1 protein through retinoylation-mediated USP7 dissociation and improves immunotherapy in pancreatic cancer
errNature Communications
IF15.7
err2026-05-11
err0
errOAAI
errChing-Fei Li; Yongkun Wei; Heng-Huan Lee; Wei-Chao Chang; Yun Xiong; Yitao Tang; Riyao Yang; Jun Yao; Huamin Wang; Xiaofei Wang; Minghui Liu; Jangho Park; Jie Fu; Ying-Nai Wang; Li-Yuan Bai; Shao-Chun Wang; Cheng-Wei Chou; Jianhua Ling; Yu-Yi Chu; Zhenzhen Xun; Han Liang; Anirban Maitra; Wantong Yao; Dihua Yu; Paul J. Chiao; Haoqiang Ying; Mien-Chie Hung
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Concurrent P-Selectin Targeting Nanoparticle Orchestrates Tumor-Immune Dynamics for Advanced Immunochemotherapy
errACS Nano
IF16
err2026-04-28
err0
errOAAI
errWei Lee; Syuan-Ling Lin; Jui-Yu Chen; Bo-Jie Huang; Wee-Wei Chieng; I-Jung Tsai; Ting-Yu Chang; Yen-Ho Lai; Wan-Zhen Hong; Kevin Chih-Yang Huang; Mien-Chie Hung; San-Yuan Chen; Long-Bin Jeng; Woei-Cherng Shyu; Chih-Sheng Chiang
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Targeting PCK1 to overcome CDK4/6 inhibitor resistance for breast cancer therapy
errCancer Letters
IF10.1
err2026-02-24
err0
PREAI
errChen-Shiou Wu; Hsiao-Fan Chen; Kieu-Thanh Huynh; Wei-Chien Huang; Yi-Chuan Li; Wei-Chao Chang; Ling-Chu Chang; Ciao-Ling Jiang; Kevin Chih-Yang Huang; Liang-Chih Liu; K.S.Clifford Chao; Mien-Chie Hung
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errSave
ZNF683+ NK cells govern chemotherapy sensitivity in advanced HPSCC via reshaping immune microenvironment
errNature Communications
IF15.7
err2026-01-21
err0
errOAAI
errGuo Li; Wenhao Xiao; Haijun Wu; Chao Liu; Liang Gong; Haoyu Zhang; Zhuo Shao; Jing Bai; Xuefeng Xia; Xin Yi; Yunyun Wang; Shanhong Lu; Li She; Juncheng Wang; Gangcai Zhu; Xiaojuan Zhou; Wenmei Wang; Liangfang Shen; Nu Zhang; Xingwei Wang; Donghai Huang; Junwei Hou; Yuanzheng Qiu; Xin Zhang; Mien-Chie Hung; Yong Liu
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A genome-wide genetic screen reveals the P2Y2-integrin axis as a stabilizer of EGFR mutants in non–small cell lung cancer (NSCLC)
errScience Advances
IF12.5
err2026-01-21
err0
errOAAI
errYafei Du; Wenjing Wang; Hui Chin Goh; Thamil Selvan Vaiyapuri; Anandhkumar Raju; Yu-Chun Hsiao; Cheng Chun Wang; Vanisha Agrawal; Noorul Farzana Mohideen; Norhidayah Binte Mohd Mazian; Feride Karatekin; Wendy Kehan Wang; Manikandan Lakshmanan; Komal Gupta; Han Chang; Xavier Le Guezennec; Frederic Bard; Daniel S. W. Tan; Vinay Tergaonkar; Mien-Chie Hung; Xiaogang Liu; Wanjin Hong; Gandhi T. K. Boopathy
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errSave
Dysregulation of PCSK9 via m6A-dependent epitranscriptomic programs fosters hepatocellular carcinoma progression
errCancer Letters
IF10.1
err2026-01-12
err0
PREAI
errWen-Lung Wang; Chih-Chieh Yen; Chia-Sheng Yen; Yu-Hsuan Huang; Hsuan-Yi Huang; Ju-Fei Chen; Yen-Yu Liu; Sih-Ting Wang; Yu-Tzu Liu; Mien-Chie Hung; Chia-Jui Yen
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errSave
YAP/TEAD-Activated TAG Synthesis and Peroxidation in Lipid Droplets Confer ROS Resistance in Cancer Stem Cells
errRedox Biology
IF11.9
err2025-12-08
err0
errOAAI
errJiun-Han Lin; Tien-Wei Hsu; Wei-Chung Cheng; Chen-Chi Liu; Anna Fen-Yau Li; Mien-Chie Hung; Han-Shui Hsu; Shih-Chieh Hung
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errSave
Targeting ephrin receptor A10 with antibody-drug conjugates for breast cancer
errCANCER LETTERS
IF10.1
err2025-12-01
err0
PREAI
errSafaei, Mahdieh; Li, Yi-Chuan; Chen, Chung-Yu; Hsieh, Ping-Hua; Venkataraman, Srimathi; Huang, Wei-Chien; Cheng, Wei-Chung; Yamaguchi, Hirohito; Chen, Yu-Fu; Ho, Yuan-Soon; Chang, Wei-Chao; Lin, Chih Wei; Hung, Mien-Chie
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Therapeutic stress triggers tumor STAT1 acetylation to disarm immunotherapy
errCell Reports Medicine
IF10.6
err2025-11-07
err0
errOAAI
errPo-Hsien Chiu; Kuan-Chen Lai; Hung-Ling Wang; Yao-Wen Chang; Wen-Chi Wu; Tien-Hua Chen; Yu-Shuen Tsai; Jie-Hong Song; Nai-Yun Sun; Gar-Yang Chau; Wen-Liang Fang; Ju-Pei Chen; Hung-Ming Wang; Huai-Cheng Huang; Meng-Che Hsieh; Chun-Hung Hua; Ming-Yu Lien; Yi-Fang Chang; Hui-Ching Wang; Chih-Yen Chien; Tai-Lin Huang; Chen-Chi Wang; Yi-Chun Liu; Jo-Pai Chen; Wei-Chen Lu; Ching-Yi Yiu; Chien-Liang Lin; Pei-Jen Lou; Pen-Yuan Chu; Shao-Chun Wang; Mien-Chie Hung; Muh-Hwa Yang
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Co-targeting CDK4/6 enhances anti-cancer activity and alleviates immune-related adverse events of anti-PD-1 antibody for breast cancer
errCell Reports Medicine
IF10.6
err2025-10-30
err0
errOAAI
errShu-Wei Hu; Ming-Hsin Yeh; Yu-Hao He; Ya-Ling Wei; Fang-Ju Cheng; Yi-Lun Yeh; Thanh Kieu Huynh; Pei-Tong Liu; Dai-Wei Hu; Tzu-Hsuan Chang; Bo-Wei Wang; Bo-Rong Chen; Mei-Chun Lin; Der-Yen Lee; Yi-Hsien Hsieh; Yuan-Man Hsu; Chih-Hsin Tang; Ping-Chih Ho; Mien-Chie Hung; Wei-Chien Huang
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errSave
MTAP deficiency confers resistance to cytosolic nucleic acid sensing and STING agonists
errScience
IF45.8
err2025-10-09
err0
PREAI
errJung-Mao Hsu; Chunxiao Liu; Weiya Xia; Chung-Yu Chen; Wei-Chung Cheng; Junwei Hou; Mien-Chie Hung
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errSave
Expression of Concern for JAK2-binding long noncoding RNA promotes breast cancer brain metastasis
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2025-10-01
err1
PREAI
errWang, Shouyu; Liang, Ke; Hu, Qingsong; Li, Ping; Song, Jian; Yang, Yuedong; Yao, Jun; Mangala, Lingegowda Selanere; Li, Chunlai; Yang, Wenhao; Park, Peter K.; Hawke, David H.; Zhou, Jianwei; Zhou, Yan; Xia, Weiya; Hung, Mien-Chie; Marks, Jeffrey R.; Gallick, Gary E.; Lopez-Berestein, Gabriel; Flores, Elsa R.; Sood, Anil K.; Huang, Suyun; Yu, Dihua; Yang, Liuqing; Lin, Chunru
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SLC6A14 Drives Mitochondrial Fusion and Oxidative Phosphorylation to Promote Cancer Stemness and Early-Onset of Breast Cancer
errAdvanced Science
IF14.1
err2025-09-17
err0
errOAAI
errDai-Wei Hu; Chih-Hao Huang; Yu-Hao He; Ya-Ling Wei; Shu-Wei Hu; Fang-Ju Cheng; Thanh Kieu Huynh; Bo-Rong Chen; Bo-Wei Wang; Li-Chi Kuan; Der-Yen Lee; Ming-Hsin Yeh; Ya-Jen Chang; Liang-Chih Liu; Mien-Chie Hung; Wei-Chien Huang
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errSave
Liver regeneration–associated hepatocellular YAP1 activation prevents colorectal cancer liver metastasis through glutamine competition
errScience Advances
IF12.5
err2025-08-22
err0
errOAAI
errQiang Yu; Mincheng Yu; Peiyi Xie; Lei Guo; Yufei Zhao; Wenxin Xu; Xian Li; Mengyuan Wu; Zihao Zhang; Zheng Chen; Yongsheng Xiao; Jian Zhou; Jia Fan; Mien-Chie Hung; Yongfeng Xu; Bo Zhang; Qinghai Ye; Hui Li
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errSave
C18-Trans-fatty acids in Cancer immunosurveillance
errCancer Letters
IF10.1
err2025-08-20
err0
PREAI
errTewodros Shegute; Chen-Shiou Wu; Wei-Chao Chang; Chung-Yu Chen; Yi-Chuan Li; Muhammad Zeshan; Hirohito Yamaguchi; Yu-Fu Chen; Zong-Shin Lin; Shin-Lei Peng; Hsiao-Fan Chen; Mien-Chie Hung
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errSave
Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function
errMolecular Cell
IF16.6
err2025-08-13
err0
PREAI
errLixin Wan; Kexin Xu; Yongkun Wei; Jinfang Zhang; Tao Han; Christopher Fry; Zhao Zhang; Yao Vickie Wang; Liyu Huang; Min Yuan; Weiya Xia; Wei-Chao Chang; Wen-Chien Huang; Chien-Liang Liu; Yuan-Ching Chang; Jinsong Liu; Yun Wu; Victor X. Jin; Xiangpeng Dai; Jianfeng Guo; Jia Liu; Shulong Jiang; Jin Li; John M. Asara; Myles Brown; Mien-Chie Hung; Wenyi Wei
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errSave
Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function
errMolecular Cell
IF16.6
err2025-07-23
err0
PREAI
errLixin Wan; Kexin Xu; Yongkun Wei; Jinfang Zhang; Tao Han; Christopher Fry; Zhao Zhang; Yao Vickie Wang; Liyu Huang; Min Yuan; Weiya Xia; Wei-Chao Chang; Wen-Chien Huang; Chien-Liang Liu; Yuan-Ching Chang; Jinsong Liu; Yun Wu; Victor X. Jin; Xiangpeng Dai; Jianfeng Guo; Jia Liu; Shulong Jiang; Jin Li; John M. Asara; Myles Brown; Mien-Chie Hung; Wenyi Wei
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Mutant p53 confers chemoresistance by activating KMT5B-mediated DNA repair pathway in nasopharyngeal carcinoma
errCANCER LETTERS
IF10.1
err2025-06-04
err0
PREAI
errLuo, Haidan; Huang, Mo-Fan; Xu, An; Wang, Donghui; Gingold, Julian A.; Tu, Jian; Wang, Ruoyu; Huo, Zijun; Chiang, Yen-Ting; Tsai, Kuang-Lei; Su, Jie; Bazer, Danielle A.; Hung, Mien-Chie; Xie, Canmao; Guo, Yubiao; Lee, Dung-Fang; Yang, Huiling; Zhao, Ruiying
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MGAT1-Guided complex N-Glycans on CD73 regulate immune evasion in triple-negative breast cancer
errNATURE COMMUNICATIONS
IF15.7
err2025-04-15
err0
errOAAI
errChi, Junlong Jack; Xie, Ping; Cheng, Mary Hongying; Zhu, Yueming; Cui, Xin; Watson, Joshua; Zeng, Lidan; Uddin, Amad; Nguyen, Hoang; Li, Lei; Moremen, Kelley; Reedy, April; Wyatt, Megan; Marcus, Adam; Dai, Mingji; Paulos, Chrystal M.; Cristofanilli, Massimo; Gradishar, William J.; Zhao, Shaying; Kalinsky, Kevin; Hung, Mine-Chie; Bahar, Ivet; Zhang, Bin
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Research Directions

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Co-authors
Cooperation Journals
G
Gordon B. Mills
H-index: 231 · Papers: 3.5K
G
Gabriel N. Hortobágyi
H-index: 187 · Papers: 1.9K
R
Ronald A. DePinho
H-index: 178 · Papers: 907
A
Anil K. Sood
H-index: 174 · Papers: 3.3K
P
Pier Paolo Pandolfi
H-index: 160 · Papers: 818
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