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Estrogen receptor signaling drives immune evasion and immunotherapy resistance in HR* breast cancer Palomeque, Jose Angel; Serra-Mir, Gabriel; Blasco-Benito, Sandra; Brunel, Helena; Torren-Duran, Pau; Perez-Nunez, Ivan; Cannata, Chiara; Comerma, Laura; Menendez, Silvia; Servitja, Sonia; Martos, Tamara; Castro, Maria; Borges, Rodrigo L.; Lopez-Velazco, Joanna I.; Manzano, Sara; Duro-Sanchez, Santiago; Arribas, Joaquin; Caffarel, Maria M.; Urruticoechea, Ander; Seoane, Jose A.; Morey, Lluis; Albanell, Joan; Celia-Terrassa, Toni Share Save
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Impact of aging on the genetic and transcriptional landscape of advanced breast cancer: an AURORA program (BIG 14-01) subanalysis Zoppoli, G.; Ravera, F.; Santaniello, F.; Ferrando, L.; Venet, D.; Seoane, J. A.; Richard, F.; Munzone, E.; Hatse, S.; Ballestrero, A.; Crestani, T. Antoniolli; Adam, V. S.; Irrthum, A.; Aftimos, P. G.; Zotano, A. L. Guerrero; Cameron, D. A.; Piccart, M.; Desmedt, C.; Benelli, M.; Wildiers, H. Share Save
RBsig geneexpression signature in patients with endocrine resistant metastatic breast cancer treated with palbociclib and fulvestrant in the PYTHIA trial Benelli, Matteo; Tyekucheva, Svitlana; Crestani, Thayane; Ignatiadis, Michail; Neven, Patrick; Colleoni, Marco; Henry, Stephanie; Papadimitriou, Konstantinos; Bernardo, Antonio; Seles, Elena; Duhoux, Francois; Macpherson, Iain; Thomson, Alastair; Davies, David Mark; Migliaccio, Ilenia; Zoppoli, Gabriele; Kammler, Roswitha; De Swert, Heidi; Ruepp, Barbara; Aftimos, Philippe; Seoane, Jose; Romagnoli, Dario; Venet, David; Goulioti, Theodora; Cameron, David; Loi, Sherene; Piccart, Martine; Regan, Meredith; Malorni, Luca Share Save
Clinical and Genomic Features of ER-Positive/HER2-negative Metastatic Breast Cancer in AURORA Molecular Screening Initiative (BIG 14-01): Mechanisms of Endocrine Therapy Resistance and Implications for Adjuvant Approaches Guerrero-Zotano, Angel; Benelli, Matteo; Irrthum, Alexandre; Cameron, David; Ferrando, Lorenzo; Romagnoli, Dario; Paoli, Marta; Llinas, Arnau; Dadiani, Maya; Fimereli, Danai; Oliveira, Mafalda; Caballero, Carmela; Crestani, Thayane; Agostinetto, Elisa; Martins-Branco, Diogo; Hilbers, Florentine; Gal-Yam, Einav; Balic, Marija; Cardoso, Fatima; Reis-Filho, Jorge; Sotiriou, Christos; Curigliano, Giuseppe; Linderholm, Barbro; de Azambuja, Evandro; Knox, Susan; Rotaru, Cristina; Ciruelos, Eva; Davidson, Nancy E.; Viale, Giuseppe; Taylor, Donatienne; Canon, Jean-Luc; Calvo, Lourdes; Albanell, Joan; Colleoni, Marco; Duhem, Caroline; Harbeck, Nadia; Herremans, Catherine; Loibl, Sibylle; Marreaud, Sandrine; Scheepers, Elsemieke; Raimbault, Alice; Goulioti, Theodora; Vingiani, Andrea; Biagioni, Chiara; Vosberg, Sebastian; Zoppoli, Gabriele; Seoane, Jose; Venet, David; Aftimos, Philippe; Piccart, Martine Share Save
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Functional screening of amplification outlier oncogenes in organoid models of early tumorigenesis Salahudeen, Ameen A.; Seoane, Jose A.; Yuki, Kanako; Mah, Amanda T.; Smith, Amber R.; Kolahi, Kevin; Sean, M. de la O.; Hart, Daniel J.; Ding, Jie; Ma, Zhicheng; Barkal, Sammy A.; Shukla, Navika D.; Zhang, Chuck H.; Cantrell, Michael A.; Batish, Arpit; Usui, Tatsuya; Root, David E.; Hahn, William C.; Curtis, Christina; Kuo, Calvin J. Share Save
ZFP281 drives a mesenchymal-like dormancy program in early disseminated breast cancer cells that prevents metastatic outgrowth in the lung Nobre, Ana Rita; Dalla, Erica; Yang, Jihong; Huang, Xin; Wullkopf, Lena; Risson, Emma; Razghandi, Pedram; Lopez Anton, Melisa; Zheng, Wei; Seoane, Jose A.; Curtis, Christina; Kenigsberg, Ephraim; Wang, Jianlong; Aguirre-Ghiso, Julio A. Share Save
The Mettl3 epitranscriptomic writer amplifies p53 stress responses Raj, Nitin; Wang, Mengxiong; Seoane, Jose A.; Zhao, Richard L.; Kaiser, Alyssa M.; Moonie, Nancie A.; Demeter, Janos; Boutelle, Anthony M.; Kerr, Craig H.; Mulligan, Abigail S.; Moffatt, Clare; Zeng, Shelya X.; Lu, Hua; Barna, Maria; Curtis, Christina; Chang, Howard Y.; Jackson, Peter K.; Attardi, Laura D. Share Save
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The Breast PreCancer Atlas DCIS genomic signatures define biology and correlate with clinical outcomes: An analysis of TBCRC 038 and RAHBT cohorts Strand, Siri H.; Rivero-Gutierrez, Belen; Houlahan, Kathleen E.; Seoane, Jose A.; King, Lorraine M.; Risom, Tyler; Simpson, Lunden; Vennam, Sujay; Khan, Aziz; Hardman, Timothy; Harmon, Bryan E.; Couch, Fergus J.; Gallagher, Kristalyn; Kilgore, Mark; Wei, Shi; DeMichele, Angela; King, Tari; McAuliffe, Priscilla F.; Nangia, Julie; Lee, Joanna; Tseng, Jennifer; Storniolo, Anna Maria; Thompson, Alastair; Gupta, Gaorav; Burns, Robyn; Veis, Deborah J.; DeSchryver, Katherine; Zhu, Chunfang; Matusiak, Magdalena; Wang, Jason; Zhu, Shirley X.; Tappenden, Jen; Ding, Daisy Yi; Zhang, Dadong; Luo, Jingqin; Jiang, Shu; Varma, Sushama; Straub, Cody; Srivastava, Sucheta; Curtis, Christina; Tibshirani, Rob; Angelo, Robert Michael; Hall, Allison; Owzar, Kouros; Polyak, Kornelia; Maley, Carlo; Marks, Jeffrey R.; Colditz, Graham A.; Hwang, E. Shelley; West, Robert B. Share Save
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A CRISPR/Cas9-Engineered ARID1A-Deficient Human Gastric Cancer Organoid Model Reveals Essential and Nonessential Modes of Oncogenic Transformation Lo, Yuan-Hung; Kolahi, Kevin S.; Du, Yuhong; Chang, Chiung-Ying; Krokhotin, Andrey; Nair, Ajay; Sobba, Walter D.; Karlsson, Kasper; Jones, Sunny J.; Longacre, Teri A.; Mah, Amanda T.; Tercan, Bahar; Sockell, Alexandra; Xu, Hang; Seoane, Jose A.; Chen, Jin; Shmulevich, Ilya; Weissman, Jonathan S.; Curtis, Christina; Califano, Andrea; Fu, Haian; Crabtree, Gerald R.; Kuo, Calvin J. Share Save
Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program Bieging-Rolett, Kathryn T.; Kaiser, Alyssa M.; Morgens, David W.; Boutelle, Anthony M.; Seoane, Jose A.; Van Nostrand, Eric L.; Zhu, Changyu; Houlihan, Shauna L.; Mello, Stephano S.; Yee, Brian A.; McClendon, Jacob; Pierce, Sarah E.; Winters, Ian P.; Wang, Mengxiong; Connolly, Andrew J.; Lowe, Scott W.; Curtis, Christina; Yeo, Gene W.; Winslow, Monte M.; Bassik, Michael C.; Attardi, Laura D. Share Save
VHIO immune gene-expression signature (VIGex) to enrich patient selection in immunotherapy (IT) phase I clinical trials Hernando-Calvo, A.; Mancuso, F. M.; Brana, I.; Santa Gadea, O. Saavedra; Vieito, M.; Alonso Casal, G.; Galvao de Aguiar, V.; Azaro Pedrazzoli, A. B.; Matos, I.; Berche, R.; Ann Worham, N.; Saura, C.; Argiles Martinez, G.; Elez, E.; Munoz Couselo, E.; Felip, E.; Seoane, J.; Tabernero, J.; Vivancos, A.; Garralda, E. Share Save
The m6A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor Xiao, Yiren; Thakkar, Kaushik N.; Zhao, Hongjuan; Broughton, James; Li, Yang; Seoane, Jose A.; Diep, Anh N.; Metzner, Thomas J.; von Eyben, Rie; Dill, David L.; Brooks, James D.; Curtis, Christina; Leppert, John T.; Ye, Jiangbin; Peehl, Donna M.; Giaccia, Amato J.; Sinha, Subarna; Rankin, Erinn B. Share Save
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