Not logged in Alterations in the CTRB2 gene and response to chemotherapy in pancreatic cancer Jazieh, Khalid; Carlson, Erin E.; Siddiqui, Zafar; Connelly, Katelyn E.; Zhong, Jun; Hoskins, Jason W.; Rabe, Kari G.; Oberg, Ann L.; Sicotte, Hugues; Carr, Ryan M.; Amundadottir, Laufey T.; Antwi, Samuel O. Share Save
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Allelic effects on KLHL17 expression underlie a pancreatic cancer genome-wide association signal at chr1p36.33 Connelly, Katelyn E.; Hullin, Katherine; Abdolalizadeh, Ehssan; Zhong, Jun; Eiser, Daina; O'Brien, Aidan; Collins, Irene; Das, Sudipto; Duncan, Gerard; Albanes, Demetrius; Andreotti, Gabriella; Arslan, Alan A.; Beane-Freeman, Laura; Berndt, Sonja I.; Buring, Julie E.; Campa, Daniele; Canzian, Federico; Chen, Yu; Chung, Charles C.; Eliassen, A. Heather; Gaziano, J. Michael; Giovannucci, Edward L.; Goodman, Phyllis J.; Haiman, Christopher A.; Hicks, Belynda; Hutchinson, Amy; Jones, Miranda R.; Katzke, Verena; Kooperberg, Charles; Kraft, Peter; Lee, I-Min; Lemarchand, Loic; Malats, Nuria; Manning, Michelle R.; Maennistoe, Satu; Milne, Roger; Moore, Steven C.; Mucci, Lorelei; Patel, Alpa V.; Peters, Ulrike; Real, Francisco X.; Rothman, Nathaniel; Sesso, Howard D.; Setiawan, Veronica W.; Shu, Xiao-Ou; Silverman, Debra; Stampfer, Meir J.; Southey, Melissa C.; Tobias, Geoffrey S.; Truong, Therese; Um, Caroline; Visvanathan, Kala; Wentzensen, Nicolas; White, Emily; Yuan, Chen; Zheng, Wei; Wactawski-Wende, Jean; Willett, Walter C.; Stoltzenberg-Solomon, Rachael Z.; Antwi, Samuel O.; Bracci, Paige M.; Gallinger, Steven; Goggins, Michael; Hassan, Manal; Holly, Elizabeth A.; Hung, Rayjean J.; Li, Donghui; Neale, Rachel E.; Rabe, Kari G.; Risch, Harvey A.; Yu, Herbert; Chanock, Stephen J.; Stolzenberg-Solomon, Rachael Z.; Klein, Alison P.; Wolpin, Brian M.; Hoskins, Jason W.; Andresson, Thorkell; Smith, Jill P.; Amundadottir, Laufey T. Share Save
A Common CTRB misfolding variant associated with pancreatic cancer risk causes ER stress and inflammation in mice Bodas, Cristina; Felipe, Irene; Chanez, Brice; Lafarga, Miguel; Lopez de Maturana, Evangelina; Martinez de Villarreal, Jaime; del Pozo, Natalia; Malumbres, Marina; Vargiu, Pierfrancesco; Cayuela, Ana; Peset, Isabel; Connelly, Katelyn; Hoskins, Jason; Mendez, Raul; Amundadottir, Laufey; Malats, Nuria; Ortega, Sagrario; Real, Francisco X. Share Save
3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity Trang, Khanh B.; Pahl, Matthew C.; Pippin, James A.; Su, Chun; Littleton, Sheridan H.; Sharma, Prabhat; Kulkarni, Nikhil N.; Ghanem, Louis R.; Terry, Natalie A.; O'Brien, Joan M.; Wagley, Yadav; Hankenson, Kurt D.; Jermusyk, Ashley; Hoskins, Jason; Amundadottir, Laufey T.; Xu, Mai; Brown, Kevin; Anderson, Stewart; Yang, Wenli; Titchenell, Paul; Seale, Patrick; Kaestner, Klaus H.; Cook, Laura; Levings, Megan; Zemel, Babette S.; Chesi, Alessandra; Wells, Andrew D.; Grant, Struan F. A. Share Save
Unraveling pancreatic cancer susceptibility at 5p15.33: Functional characterization of a novel VNTR element O'Brien, Aidan; Kong, Hyunkyung; Patel, Minal; Connelly, Katelyn E.; Xu, Mai; Collins, Irene; Zhong, Jun; Hoskins, Jason; Ho, Michelle; Papenburg, Brenen; Iles, Mark M.; Law, Matthew H.; Landi, Maria-Teresa; Stolzenber-Solomon, Rachael; Wolpin, Brian M.; Klein, Alison P.; Orr, Nick; Chanock, Stephen J.; Lindstrom, Sara; Stern, Marc-Henri; Prokunina-Olsson, Ludmila; Choi, Jieyon; Brown, Kevin M.; Amundadottir, Laufey T. Share Save
The functional characterization of pancreatic ductal adenocarcinoma GWAS risk variants in primary pancreatic cells - A pilot study Patel, Minal B.; O'Brien, Aidan; Zhong, Jun; Collins, Irene; Hoskins, Jason W.; Chanock, Stephen J.; Antwi, Samuel O.; Stolzenberg-Solomon, Rachel Z.; Klein, Alison P.; Wolpin, Brian M.; Lindstrom, Sara; Arda, H. Efsun; Brown, Kevin M.; Connelly, Katelyn E.; Amundadottir, Laufey T.; Jezek, Meagan Share Save
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Functional characterization of the 1p36.33 pancreatic cancer GWAS locus Connelly, Katelyn E.; Hullin, Katherine; Abdolalizadeh, Ehssan; Zhong, Jun; Eiser, Daina; Hoskins, Jason W.; O'Brien, Aidan; Collins, Irene; Chanock, Stephen J.; Stolzenberg-Solomon, Rachael Z.; Klein, Alison P.; Wolpin, Brian M.; Smith, Jill P.; Amundadottir, Laufey Share Save
High-throughput characterization of functional variants highlights heterogeneity and polygenicity underlying lung cancer susceptibility Long, Erping; Patel, Harsh; Golden, Alyxandra; Antony, Michelle; Yin, Jinhu; Funderburk, Karen; Feng, James; Song, Lei; Hoskins, Jason W.; Amundadottir, Laufey T.; Hung, Rayjean J.; Amos, Christopher I.; Shi, Jianxin; Rothman, Nathaniel; Lan, Qing; Choi, Jiyeon Share Save
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A 584 bp deletion in CTRB2 inhibits chymotrypsin B2 activity and secretion and confers risk of pancreatic cancer Jermusyk, Ashley; Zhong, Jun; Connelly, Katelyn E.; Gordon, Naomi; Perera, Sumeth; Abdolalizadeh, Ehssan; Zhang, Tongwu; O'Brien, Aidan; Hoskins, Jason W.; Collins, Irene; Eiser, Daina; Yuan, Chen; Risch, Harvey A.; Jacobs, Eric J.; Li, Donghui; Du, Mengmeng; Stolzenberg-Solomon, Rachael Z.; Klein, Alison P.; Smith, Jill P.; Wolpin, Brian M.; Chanock, Stephen J.; Shi, Jianxin; Petersen, Gloria M.; Westlake, Christopher J.; Amundadottir, Laufey T. Share Save
A Transcriptome-Wide Association Study Identifies Novel Candidate Susceptibility Genes for Pancreatic Cancer Zhong, Jun; Jermusyk, Ashley; Wu, Lang; Hoskins, Jason W.; Collins, Irene; Mocci, Evelina; Zhang, Mingfeng; Song, Lei; Chung, Charles C.; Zhang, Tongwu; Xiao, Wenming; Albanes, Demetrius; Andreotti, Gabriella; Arslan, Alan A.; Babic, Ana; Bamlet, William R.; Beane-Freeman, Laura; Berndt, Sonja; Borgida, Ayelet; Bracci, Paige M.; Brais, Lauren; Brennan, Paul; Bueno-de-Mesquita, Bas; Buring, Julie; Canzian, Federico; Childs, Erica J.; Cotterchio, Michelle; Du, Mengmeng; Duell, Eric J.; Fuchs, Charles; Gallinger, Steven; Gaziano, J. Michael; Giles, Graham G.; Giovannucci, Edward; Goggins, Michael; Goodman, Gary E.; Goodman, Phyllis J.; Haiman, Christopher; Hartge, Patricia; Hasan, Manal; Helzlsouer, Kathy J.; Holly, Elizabeth A.; Klein, Eric A.; Kogevinas, Manolis; Kurtz, Robert J.; LeMarchand, Loic; Malats, Nuria; Mannisto, Satu; Milne, Roger; Neale, Rachel E.; Ng, Kimmie; Obazee, Ofure; Oberg, Ann L.; Orlow, Irene; Patel, Alpa, V; Peters, Ulrike; Porta, Miquel; Rothman, Nathaniel; Scelo, Ghislaine; Sesso, Howard D.; Severi, Gianluca; Sieri, Sabina; Silverman, Debra; Sund, Malin; Tjonneland, Anne; Thornquist, Mark D.; Tobias, Geoffrey S.; Trichopoulou, Antonia; Van den Eeden, Stephen K.; Visvanathan, Kala; Wactawski-Wende, Jean; Wentzensen, Nicolas; White, Emily; Yu, Herbert; Yuan, Chen; Zeleniuch-Jacquotte, Anne; Hoover, Robert; Brown, Kevin; Kooperberg, Charles; Risch, Harvey A.; Jacobs, Eric J.; Li, Donghui; Yu, Kai; Shu, Xiao-Ou; Chanock, Stephen J.; Wolpin, Brian M.; Stolzenberg-Solomon, Rachael Z.; Chatterjee, Nilanjan; Klein, Alison P.; Smith, Jill P.; Kraft, Peter; Shi, Jianxin; Petersen, Gloria M.; Zheng, Wei; Amundadottir, Laufey T. Share Save
Large-scale transcriptome-wide association study (TWAS) identifies novel candidate susceptibility genes for pancreatic cancer Zhong, Jun; Jermusyk, Ashley; Wu, Lang; Hoskins, Jason W.; Collins, Irene; Zhang, Mingfeng; Lei, Song; Chung, Charles C.; Zhang, Tongwu; Xiao, Wenming; Stolzenberg-Solomon, Rachael; Klein, Alison P.; Wolpin, Brian M.; Shu, Xiao-Ou; Chanock, Stephen J.; Olson, Sara; Chatterjee, Nilanjan; Smith, Jill; Shi, Jianxin; Kraft, Peter; Petersen, Gloria M.; Zheng, Wei; Amundadottir, Laufey T. Share Save
Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer Klein, Alison P.; Wolpin, Brian M.; Risch, Harvey A.; Stolzenberg-Solomon, Rachael Z.; Mocci, Evelina; Zhang, Mingfeng; Canzian, Federico; Childs, Erica J.; Hoskins, Jason W.; Jermusyk, Ashley; Zhong, Jun; Chen, Fei; Albanes, Demetrius; Andreotti, Gabriella; Arslan, Alan A.; Babic, Ana; Bamlet, William R.; Beane-Freeman, Laura; Berndt, Sonja I.; Blackford, Amanda; Borges, Michael; Borgida, Ayelet; Bracci, Paige M.; Brais, Lauren; Brennan, Paul; Brenner, Hermann; Bueno-de-Mesquita, Bas; Buring, Julie; Campa, Daniele; Capurso, Gabriele; Cavestro, Giulia Martina; Chaffee, Kari G.; Chung, Charles C.; Cleary, Sean; Cotterchio, Michelle; Dijk, Frederike; Duell, Eric J.; Foretova, Lenka; Fuchs, Charles; Funel, Niccola; Gallinger, Steven; Gaziano, J. Michael M.; Gazouli, Maria; Giles, Graham G.; Giovannucci, Edward; Goggins, Michael; Goodman, Gary E.; Goodman, Phyllis J.; Hackert, Thilo; Haiman, Christopher; Hartge, Patricia; Hasan, Manal; Hegyi, Peter; Helzlsouer, Kathy J.; Herman, Joseph; Holcatova, Ivana; Holly, Elizabeth A.; Hoover, Robert; Hung, Rayjean J.; Jacobs, Eric J.; Jamroziak, Krzysztof; Janout, Vladimir; Kaaks, Rudolf; Khaw, Kay-Tee; Klein, Eric A.; Kogevinas, Manolis; Kooperberg, Charles; Kulke, Matthew H.; Kupcinskas, Juozas; Kurtz, Robert J.; Laheru, Daniel; Landi, Stefano; Lawlor, Rita T.; Lee, I. -Min; LeMarchand, Loic; Lu, Lingeng; Malats, Nuria; Mambrini, Andrea; Mannisto, Satu; Milne, Roger L.; Mohelnikova-Duchonova, Beatrice; Neale, Rachel E.; Neoptolemos, John P.; Oberg, Ann L.; Olson, Sara H.; Orlow, Irene; Pasquali, Claudio; Patel, Alpa V.; Peters, Ulrike; Pezzilli, Raffaele; Porta, Miquel; Real, Francisco X.; Rothman, Nathaniel; Scelo, Ghislaine; Sesso, Howard D.; Severi, Gianluca; Shu, Xiao-Ou; Silverman, Debra; Smith, Jill P.; Soucek, Pavel; Sund, Malin; Talar-Wojnarowska, Renata; Tavano, Francesca; Thornquist, Mark D.; Tobias, Geoffrey S.; Van Den Eeden, Stephen K.; Vashist, Yogesh; Visvanathan, Kala; Vodicka, Pavel; Wactawski-Wende, Jean; Wang, Zhaoming; Wentzensen, Nicolas; White, Emily; Yu, Herbert; Yu, Kai; Zeleniuch-Jacquotte, Anne; Zheng, Wei; Kraft, Peter; Li, Donghui; Chanock, Stephen; Obazee, Ofure; Petersen, Gloria M.; Amundadottir, Laufey T. Share Save
Analysis of cis-eQTLs in normal and tumor-derived pancreatic tissues reveals functional insights, including for the 9q34.1 ABO pancreatic cancer risk locus Amundadottir, Laufey T.; Andresen, Soren Lykke; Xiao, Wenming; Hoskins, Jason; Jermusyk, Ashley; Rost, Lauren; Collins, Irene; Jia, Jinping; Mobaraki, Michael; Zhu, Bin; Kurtz, Robert; Parikh, Hemang; Song, Lei; Yeager, Meredith; Jensen, Torben; Bamlet, William; Chatterjee, Nilanjan; Wolpin, Brian; Smith, Jill; Olson, Sara; Petersen, Gloria; Shi, Jianxin; Zhang, Mingfeng Share Save
Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148 Fang, Jun; Jia, Jinping; Makowski, Matthew; Xu, Mai; Wang, Zhaoming; Zhang, Tongwu; Hoskins, Jason W.; Choi, Jiyeon; Han, Younghun; Zhang, Mingfeng; Thomas, Janelle; Kovacs, Michael; Collins, Irene; Dzyadyk, Marta; Thompson, Abbey; O'Neill, Maura; Das, Sudipto; Lan, Qi; Koster, Roelof; Stolzenberg-Solomon, Rachael S.; Kraft, Peter; Wolpin, Brian M.; Jansen, Pascal W. T. C.; Olson, Sara; McGlynn, Katherine A.; Kanetsky, Peter A.; Chatterjee, Nilanjan; Barrett, Jennifer H.; Dunning, Alison M.; Taylor, John C.; Newton-Bishop, Julia A.; Bishop, D. Timothy; Andresson, Thorkell; Petersen, Gloria M.; Amos, Christopher I.; Iles, Mark M.; Nathanson, Katherine L.; Landi, Maria Teresa; Vermeulen, Michiel; Brown, Kevin M.; Amundadottir, Laufey T. Share Save
Functional characterization of a chr13q22.1 pancreatic cancer risk locus reveals long-range interaction and allele-specific effects on DIS3 expression Hoskins, Jason W.; Ibrahim, Abdisamad; Emmanuel, Mickey A.; Manmiller, Sarah M.; Wu, Yinglun; O'Neill, Maura; Jia, Jinping; Collins, Irene; Zhang, Mingfeng; Thomas, Janelle V.; Rost, Lauren M.; Das, Sudipto; Parikh, Hemang; Haake, Jefferson M.; Matters, Gail L.; Kurtz, Robert C.; Bamlet, William R.; Klein, Alison; Stolzenberg-Solomon, Rachael; Wolpin, Brian M.; Yarden, Ronit; Wang, Zhaoming; Smith, Jill; Olson, Sara H.; Andresson, Thorkell; Petersen, Gloria M.; Amundadottir, Laufey T. Share Save
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