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Ana Paula Silva

faculty of medicine

38H-index
98Paper Count
3.8KCitation Count
Published Papers 32
Publication Date
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Intranasal 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) Administration Hampered Contractile Response of Dopamine in Isolated Rat Ileum
errBiomedicines 2025, Vol. 13, Page 2400
IF3.9
err2025-09-30
err0
errOAAI
errAna Silva; Sofia Viana; Inês Pita; Cristina Lemos; Filipe C. Matheus; Lina Carvalho; Carlos A. Fontes Ribeiro; Rui D. Prediger; Frederico C. Pereira; Sónia Silva
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Methylphenidate triggers retinal oxidative stress and mitochondrial dysfunction under physiological conditions but has beneficial effects in inflammatory settings
errNeuropharmacology
IF4.6
err2025-08-05
err0
errOAAI
errEliane S. Sanches; Ricardo A. Leitão; Filipa I. Baptista; Sandra I. Mota; Margarida V. Caldeira; Paulo J. Oliveira; António F. Ambrósio; Rosa Fernandes; Ana P. Silva
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Distinct behavioural and neurovascular signatures induced by acute and chronic stress in rats
errBehavioural Brain Research
IF2.3
err2025-06-16
err0
errOAAI
errDaniela M. Simões; José Carreira; Alexandre Henriques; Rita Gaspar; Eliane S. Sanches; Filipa I. Baptista; Ana Paula Silva
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errSave
Neurovascular dysfunction in psychiatric disorders: Underlying mechanisms and therapeutic approaches
errEUROPEAN JOURNAL OF CLINICAL INVESTIGATION
IF3.6
err2024-09-23
err0
PREAI
errSanches, Eliane Swely; Simoes, Daniela; Baptista, Filipa Isabel; Silva, Ana Paula
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ENPP1 induces blood-brain barrier dysfunction and promotes brain metastasis formation in human epidermal growth factor receptor 2-positive breast cancer
errNEURO-ONCOLOGY
IF13.4
err2024-08-30
err1
errOAAI
errSantos, Liliana; Tomatis, Francesca; Ferreira, Hugo R. S.; Almeida, Sara F. F.; Ciputra, Edward; Sereno, Jose; Almeida, Rui; Teixeira, Paulo; Ribeiro, Ana Sofia; Moreira, Joao N.; Silva, Ana P.; Ferreira, Lino; Abrunhosa, Antero J.; Gomes, Celia M.
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Nerve growth factor inducible (VGF) is a secreted mediator for metastatic breast cancer tropism to the brain
errJOURNAL OF PATHOLOGY
IF5.2
err2024-07-29
err2
PREAI
errCarvalho, Rita; Santos, Liliana; Conde, Ines; Leitao, Ricardo; Ferreira, Hugo R. S.; Gomes, Celia; Silva, Ana Paula; Schmitt, Fernando; Carvalho-Maia, Carina; Lobo, Joao; Jeronimo, Carmen; Paredes, Joana; Ribeiro, Ana Sofia
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Attention-Deficit/Hyperactivity Disorder Animal Model Presents Retinal Alterations and Methylphenidate Has a Differential Effect in ADHD versus Control Conditions
errANTIOXIDANTS
IF6.6
err2023-04-15
err7
errOAAI
errSanches, Eliane S.; Boia, Raquel; Leitao, Ricardo A.; Madeira, Maria H.; Fontes-Ribeiro, Carlos A.; Ambrosio, Antonio Francisco; Fernandes, Rosa; Silva, Ana Paula
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ApoE Mimetic Peptides to Improve the Vicious Cycle of Malnutrition and Enteric Infections by Targeting the Intestinal and Blood-Brain Barriers
errPHARMACEUTICS
IF5.5
err2023-03-28
err1
errOAAI
errOria, Reinaldo B.; Freitas, Raul S.; Roque, Cassia R.; Nascimento, Jose Carlos R.; Silva, Ana Paula; Malva, Joao O.; Guerrant, Richard L.; Vitek, Michael P.
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The effect of parthenolide on methamphetamine-induced blood-brain barrier and astrocyte alterations
errEUROPEAN JOURNAL OF CLINICAL INVESTIGATION
IF3.6
err2021-11-03
err7
PREAI
errLeitao, Ricardo A.; Fontes-Ribeiro, Carlos A.; Silva, Ana Paula
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errSave
Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration
errCELL REPORTS
IF6.9
err2020-06-01
err67
errOAAI
errSocodato, Renato; Portuga, Camila C.; Canedo, Teresa; Rodrigues, Artur; Almeida, Tiago O.; Henriques, Joana F.; Vaz, Sandra H.; Magalhaes, Joao; Silva, Catia M.; Baptista, Filipa, I; Alves, Renata L.; Coelho-Santos, Vanessa; Silva, Ana Paula; Paes-de-Carvalho, Roberto; Magalhaes, Ana; Brakebusch, Cord; Sebastiao, Ana M.; Summavielle, Teresa; Ambrosio, Antonio F.; Relvas, Joao B.
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Effect of chronic methylphenidate treatment on hippocampal neurovascular unit and memory performance in late adolescent rats
errEUROPEAN NEUROPSYCHOPHARMACOLOGY
IF6.7
err2019-02-01
err17
PREAI
errCoelho-Santos, Vanessa; Cardoso, Filipa L.; Magalhaes, Ana; Ferreira-Teixeira, Margarida; Leitao, Ricardo A.; Gomes, Celia; Rito, Manuel; Barbosa, Marcos; Fontes-Ribeiro, Carlos A.; Silva, Ana Paula
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Effect of Hypoproteic and High-Fat Diets on Hippocampal Blood-Brain Barrier Permeability and Oxidative Stress
errFRONTIERS IN NUTRITION
IF5.1
err2019-01-09
err53
errOAAI
errde Aquino, Cristhyane Costa; Leitao, Ricardo A.; Oliveira Alves, Luis A.; Coelho-Santos, Vanessa; Guerrant, Richard L.; Ribeiro, Carlos F.; Malva, Joao O.; Silva, Ana P.; Oria, Reinaldo B.
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The dipeptidyl peptidase-4 (DPP-4) inhibitor sitagliptin ameliorates retinal endothelial cell dysfunction triggered by inflammation
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2018-06-01
err22
PREAI
errGoncalves, Andreia; Almeida, Luisa; Silva, Ana Paula; Fontes-Ribeiro, Carlos; Ambrosio, Antonio F.; Cristovao, Armando; Fernandes, Rosa
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errSave
Molecular mechanisms regulating glia homeostasis
errFREE RADICAL BIOLOGY AND MEDICINE
IF8.2
err2018-05-01
err0
PREAI
errSocodato, Renato; Portugal, Camila C.; Canedo, Teresa; Henriques, Joana; Vaz, Sandra; Magalhaes, Joao; Silva, Catia M.; Baptista, Filipa; Alves, Renata L.; Nogueira, Jose; Coelho-Santos, Vanessa; Silva, Ana Paula; Paes-de-Carvalho, Roberto; Magalhaes, Ana; Summavielle, Teresa; Brakebusch, Cord; Sebastiao, Ana; Ambrosio, Antonio F.; Relvas, Joao B.
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Impact of developmental exposure to methylphenidate on rat brain's immune privilege and behavior: Control versus ADHD model
errBRAIN BEHAVIOR AND IMMUNITY
IF7.6
err2018-02-01
err28
PREAI
errCoelho-Santos, Vanessa; Cardoso, Filipa L.; Leitao, Ricardo A.; Fontes-Ribeiro, Carlos A.; Silva, Ana Paula
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Testing the excitation/inhibition imbalance hypothesis in a mouse model of the autism spectrum disorder: in vivo neurospectroscopy and molecular evidence for regional phenotypes
errMOLECULAR AUTISM
IF5.5
err2017-09-19
err64
errOAAI
errGoncalves, Joana; Violante, Ines R.; Sereno, Jose; Leitao, Ricardo A.; Cai, Ying; Abrunhosa, Antero; Silva, Ana Paula; Silva, Alcino J.; Castelo-Branco, Miguel
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Impact of Neuroinflammation on Hippocampal Neurogenesis: Relevance to Aging and Alzheimer's Disease
errJOURNAL OF ALZHEIMERS DISEASE
IF3.1
err2017-09-15
err64
PREAI
errValero, Jorge; Bernardino, Liliana; Cardoso, Filipa Lourenco; Silva, Ana Paula; Fontes-Ribeiro, Carlos; Ambrosio, Antonio Francisco; Malva, Joao Oliveira
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errSave
Extended-access methamphetamine self-administration elicits neuroinflammatory response along with blood-brain barrier breakdown
errBRAIN BEHAVIOR AND IMMUNITY
IF7.6
err2017-05-01
err45
PREAI
errGoncalves, Joana; Leitao, Ricardo A.; Higuera-Matas, Alejandro; Amparo Assis, Maria; Coria, Santiago M.; Fontes-Ribeiro, Carlos; Ambrosio, Emilio; Silva, Ana Paula
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Methylphenidate-triggered ROS generation promotes caveolae-mediated transcytosis via Rac1 signaling and c-Src-dependent caveolin-1 phosphorylation in human brain endothelial cells
errCELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
err2016-07-04
err30
errOAAI
errCoelho-Santos, Vanessa; Socodato, Renato; Portugal, Camila; Leitao, Ricardo A.; Rito, Manuel; Barbosa, Marcos; Couraud, Pierre-Olivier; Romero, Ignacio A.; Weksler, Babette; Minshall, Richard D.; Fontes-Ribeiro, Carlos; Summavielle, Teresa; Relvas, Joao B.; Silva, Ana P.
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The TNF-α/NF-κB signaling pathway has a key role in methamphetamine-induced blood-brain barrier dysfunction
errJOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
IF4.5
err2015-04-22
err83
errOAAI
errCoelho-Santos, Vanessa; Leitao, Ricardo A.; Cardoso, Filipa L.; Palmela, Ines; Rito, Manuel; Barbosa, Marcos; Brito, Maria A.; Fontes-Ribeiro, Carlos A.; Silva, Ana P.
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Research Directions

No research directions
Co-authors
Cooperation Journals
C
Catarina R. Oliveira
H-index: 97 · Papers: 512
A
Alcino J. Silva
H-index: 97 · Papers: 333
R
Richard L. Guerrant
H-index: 91 · Papers: 686
R
Rodrigo A. Cunha
H-index: 89 · Papers: 457
C
Cord Brakebusch
H-index: 81 · Papers: 305
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