Not logged inHistone methyltransferase ASH1L primes metastases and metabolic reprogramming of macrophages in the bone niche
Meng, Chenling; Lin, Kevin; Shi, Wei; Teng, Hongqi; Wan, Xinhai; Debruine, Anna; Wang, Yin; Liang, Xin; Leo, Javier; Chen, Feiyu; Gu, Qianlin; Zhang, Jie; Van, Vivien; Maldonado, Kiersten L.; Gan, Boyi; Lu, Yue; Zhao, Di .png)
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SaveCHD1 loss reprograms SREBP2-driven cholesterol synthesis to fuel androgen-responsive growth and castration resistance in SPOP-mutated prostate tumorsChen, Feiyu; Li, Haoyan; Wang, Yin; Tang, Ximing; Lin, Kevin; Li, Qidong; Meng, Chenling; Shi, Wei; Leo, Javier; Liang, Xin; Zhang, Jie; Van, Vivien; Mahmud, Iqbal; Wei, Bo; Lorenzi, Philip L.; Raso, Maria G.; Aparicio, Ana; Lu, Yue; Frigo, Daniel E.; Gan, Boyi Share Save Share Save Immune checkpoint B7-H3 is a therapeutic vulnerability in prostate cancer harboring PTEN and TP53 deficienciesShi, Wei; Wang, Yin; Zhao, Yuehui; Kim, Justin Jimin; Li, Haoyan; Meng, Chenling; Chen, Feiyu; Zhang, Jie; Mak, Duncan H.; Van, Vivien; Leo, Javier; Croix, Brad St; Aparicio, Ana; Zhao, Di Share Save Share Save Chromatin Regulator CHD1 Remodels the Immunosuppressive Tumor Microenvironment, in PTEN-Deficient Prostate CancerZhao, Di; Cai, Li; Lu, Xin; Liang, Xin; Li, Jiexi; Chen, Peiwen; Ittmann, Michael; Shang, Xiaoying; Jiang, Shan; Li, Haoyan; Meng, Chenling; Flores, Ivonne; Song, Jian H.; Horner, James W.; Lan, Zhengdao; Wu, Chang-Jiun; Li, Jun; Chang, Qing; Chen, Ko-Chien; Wang, Guocan; Deng, Pingna; Spring, Denise J.; Wang, Y. Alan; DePinho, Ronald A. Share Save An In Vivo Screen Identifies PYGO2 as a Driver for Metastatic Prostate CancerLu, Xin; Pan, Xiaolu; Wu, Chang-Jiun; Zhao, Di; Feng, Shan; Zang, Yong; Lee, Rumi; Khadka, Sunada; Amin, Samirkumar B.; Jin, Eun-Jung; Shang, Xiaoying; Deng, Pingna; Luo, Yanting; Morgenlander, William R.; Weinrich, Jacqueline; Lu, Xuemin; Jiang, Shan; Chang, Qing; Navone, Nora M.; Troncoso, Patricia; DePinho, Ronald A.; Wang, Y. Alan Share Save Targeting YAP-Dependent MDSC Infiltration Impairs Tumor ProgressionWang, Guocan; Lu, Xin; Dey, Prasenjit; Deng, Pingna; Wu, Chia Chin; Jiang, Shan; Fang, Zhuangna; Zhao, Kuo; Konaparthi, Ramakrishna; Hua, Sujun; Zhang, Jianhua; Li-Ning-Tapia, Elsa M.; Kapoor, Avnish; Wu, Chang-Jiun; Patel, Neelay Bhaskar; Guo, Zhenglin; Ramamoorthy, Vandhana; Tieu, Trang N.; Heffernan, Tim; Zhao, Di; Shang, Xiaoying; Khadka, Sunada; Hou, Pingping; Hu, Baoli; Jin, Eun-Jung; Yao, Wantong; Pan, Xiaolu; Ding, Zhihu; Shi, Yanxia; Li, Liren; Chang, Qing; Troncoso, Patricia; Logethetis, Christopher J.; McArthur, Mark J.; Chin, Lynda; Wang, Y. Alan; DePinho, Ronaldo A. Share Save Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancerKapoor, Avnish; Yao, Wantong; Ying, Haoqiang; Hua, Sujun; Liewen, Alison; Sadanandam, Anguraj; Al-Khalil, Ramsey; Viale, Andrea; Pettazzoni, Piergiorgio; Sanchez, Nora; Protopopov, Alexei; Zhang, Jianhua; Heffernan, Timothy; Johnson, Randy L.; Chin, Lynda; Wang, Y. Alan; Draetta, Giulio; DePinho, Ronald A. Share Save Share Save 
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