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Leonardo M. Cortez

university of alberta

14H-index
40Paper Count
718Citation Count
Published Papers 14
Publication Date
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Understanding the Phenotypic Heterogeneity Within the Sporadic Creutzfeldt–Jakob Disease MV1 Subtype
errNeuropathology and Applied Neurobiology
IF3.4
err2026-05-05
err0
errOAAI
errSatish K. Nemani; Leonardo M. Cortez; Jennifer Myskiw; Ignazio Cali; Stephanie A. Booth; Gerard H. Jansen; Valerie L. Sim
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Gangliosides modulate the secretion of extracellular vesicles and their misfolded protein cargo
errScience Advances
IF12.5
err2025-09-17
err0
errOAAI
errJohn Monyror; Vaibhavi Kadam; Luis Carlos Morales; Diego Ordóñez; Jeremies Ibanga; Asifa K. Zaidi; Emily McNamara; Desmond Pink; Magnus Stenlund; Ken Reyes; Aislinn D. Maguire; Jing Huang; Leonardo M. Cortez; Valerie L. Sim; Sue-Ann Mok; Elena Posse de Chaves; Simonetta Sipione
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Alzheimer's disease associated isoforms of human CD33 distinctively modulate microglial cell responses in 5XFAD mice
errMOLECULAR NEURODEGENERATION
IF17.5
err2024-05-27
err2
errOAAI
errEskandari-Sedighi, Ghazaleh; Crichton, Madeline; Zia, Sameera; Gomez-Cardona, Erik; Cortez, Leonardo M.; Patel, Zain H.; Takahashi-Yamashiro, Kei; St. Laurent, Chris D.; Sidhu, Gaurav; Sarkar, Susmita; Aghanya, Vivian; Sim, Valerie L.; Tan, Qiumin; Julien, Olivier; Plemel, Jason R.; Macauley, Matthew S.
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Rational design of structure-based vaccines targeting misfolded alpha-synuclein conformers of Parkinson's disease and related disorders
errBIOENGINEERING & TRANSLATIONAL MEDICINE
IF5.7
err2024-04-09
err0
errOAAI
errFlores-Fernandez, Jose Miguel; Pesch, Verena; Sriraman, Aishwarya; Chimal-Juarez, Enrique; Amidian, Sara; Wang, Xiongyao; Duckering, Caleb; Fang, Andrew; Reithofer, Sara; Ma, Liang; Cortez, Leonardo M.; Sim, Valerie L.; Tamgueney, Gueltekin; Wille, Holger
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Implications of exosomes derived from cholesterol-accumulated astrocytes in Alzheimer's disease pathology
errDISEASE MODELS & MECHANISMS
IF3.3
err2021-10-26
err16
errOAAI
errWu, Qi; Cortez, Leonardo; Kamali-Jamil, Razieh; Sim, Valerie; Wille, Holger; Kar, Satyabrata
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Asymmetric-flow field-flow fractionation of prions reveals a strain-specific continuum of quaternary structures with protease resistance developing at a hydrodynamic radius of 15 nm
errPLOS PATHOGENS
IF4.9
err2021-06-28
err16
errOAAI
errCortez, Leonardo M.; Nemani, Satish K.; Duque Velasquez, Camilo; Sriraman, Aishwarya; Wang, YongLiang; Wille, Holger; McKenzie, Debbie; Sim, Valerie L.
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Native nanodiscs formed by styrene maleic acid copolymer derivatives help recover infectious prion multimers bound to brain-derived lipids
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2020-06-01
err15
errOAAI
errEsmaili, Mansoore; Tancowny, Brian P.; Wang, Xiongyao; Moses, Audric; Cortez, Leonardo M.; Sim, Valerie L.; Wille, Holger; Overduin, Michael
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Early stages of aggregation of engineered α-synuclein monomers and oligomers in solution
errSCIENTIFIC REPORTS
IF3.9
err2019-02-11
err45
errOAAI
errLi, Xi; Dong, Chunhua; Hoffmann, Marion; Garen, Craig R.; Cortez, Leonardo M.; Petersen, Nils O.; Woodside, Michael T.
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Pharmacological chaperone reshapes the energy landscape for folding and aggregation of the prion protein
errNATURE COMMUNICATIONS
IF15.7
err2016-06-27
err39
errOAAI
errGupta, Amar Nath; Neupane, Krishna; Rezajooei, Negar; Cortez, Leonardo M.; Sim, Valerie L.; Woodside, Michael T.
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errSave
Toll-like Receptor-mediated Immune Response Inhibits Prion Propagation
errGLIA
IF5.1
err2016-02-16
err20
PREAI
errKang, Sang-Gyun; Kim, Chiye; Cortez, Leonardo M.; Garza, Maria Carmen; Yang, Jing; Wille, Holger; Sim, Valerie L.; Westaway, David; McKenzie, Debbie; Aiken, Judd
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Bile Acids Reduce Prion Conversion, Reduce Neuronal Loss, and Prolong Male Survival in Models of Prion Disease
errJOURNAL OF VIROLOGY
IF3.8
err2015-08-01
err51
errOAAI
errCortez, Leonardo M.; Campeau, Jody; Norman, Grant; Kalayil, Marian; Van der Merwe, Jacques; McKenzie, Debbie; Sim, Valerie L.
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Mouse Prion Protein Polymorphism Phe-108/Val-189 Affects the Kinetics of Fibril Formation and the Response to Seeding EVIDENCE FOR A TWO-STEP NUCLEATION POLYMERIZATION MECHANISM
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2013-02-01
err16
errOAAI
errCortez, Leonardo M.; Kumar, Jitendra; Renault, Ludovic; Young, Howard S.; Sim, Valerie L.
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Characterization of Heparin-induced Glyceraldehyde-3-phosphate Dehydrogenase Early Amyloid-like Oligomers and Their Implication in α-Synuclein Aggregation
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2012-01-01
err27
errOAAI
errTorres-Bugeau, Clarisa M.; Avila, Cesar L.; Raisman-Vozari, Rita; Papy-Garcia, Dulce; Itri, Rosangela; Barbosa, Leandro R. S.; Cortez, Leonardo M.; Sim, Valerie L.; Chehin, Rosana N.
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Glyceraldehyde-3-phosphate dehydrogenase tetramer dissociation and amyloid fibril formation induced by negatively charged membranes
errFEBS LETTERS
IF3
err2009-12-13
err12
errOAAI
errCortez, Leonardo M.; Avila, Cesar L.; Torres Bugeau, Clarisa M.; Farias, Ricardo N.; Morero, Roberto D.; Chehin, Rosana N.
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Research Directions

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Co-authors
Cooperation Journals
D
David Westaway
H-index: 68 · Papers: 247
J
Judd M. Aiken
H-index: 50 · Papers: 168
R
Rita Raisman‐Vozari
H-index: 48 · Papers: 174
M
Matthew S. Macauley
H-index: 48 · Papers: 190
H
Holger Wille
H-index: 48 · Papers: 164
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