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Differences in SMA-like polymer architecture dictate the conformational changes exhibited by the membrane protein rhodopsin encapsulated in lipid nano-particles Grime, Rachael L.; Logan, Richard T.; Nestorow, Stephanie A.; Sridhar, Pooja; Edwards, Patricia C.; Tate, Christopher G.; Klumperman, Bert; Dafforn, Tim R.; Poyner, David R.; Reeves, Philip J.; Wheatley, Mark Share Save
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An acid-compatible co-polymer for the solubilization of membranes and proteins into lipid bilayer-containing nanoparticles Hall, Stephen C. L.; Tognoloni, Cecilia; Charlton, Jack; Bragginton, Eilis C.; Rothnie, Alice J.; Sridhar, Pooja; Wheatley, Mark; Knowles, Timothy J.; Arnold, Thomas; Edler, Karen J.; Dafforn, Tim R. Share Save
GPCR-styrene maleic acid lipid particles (GPCR-SMALPs): their nature and potential Wheatley, Mark; Charlton, Jack; Jamshad, Mohammed; Routledge, Sarah J.; Bailey, Sian; La-Borde, Penelope J.; Azam, Maria T.; Logan, Richard T.; Bill, Roslyn M.; Dafforn, Tim R.; Poyner, David R. Share Save
G-protein coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent Jamshad, Mohammed; Charlton, Jack; Lin, Yu-Pin; Routledge, Sarah J.; Bawa, Zharain; Knowles, Timothy J.; Overduin, Michael; Dekker, Niek; Dafforn, Tim R.; Bill, Roslyn M.; Poyner, David R.; Wheatley, Mark Share Save
Structural analysis of a nanoparticle containing a lipid bilayer used for detergent-free extraction of membrane proteins Jamshad, Mohammed; Grimard, Vinciane; Idini, Ilaria; Knowles, Tim J.; Dowle, Miriam R.; Schofield, Naomi; Sridhar, Pooja; Lin, Yupin; Finka, Rachael; Wheatley, Mark; Thomas, Owen R. T.; Palmer, Richard E.; Overduin, Michael; Govaerts, Cedric; Ruysschaert, Jean-Marie; Edler, Karen J.; Dafforn, Tim R. Share Save
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Surfactant-free purification of membrane proteins with intact native membrane environment Jamshad, Mohammed; Lin, Yu-Pin; Knowles, Timothy J.; Parslow, Rosemary A.; Harris, Craig; Wheatley, Mark; Poyner, David R.; Bill, Roslyn M.; Thomas, Owen R. T.; Overduin, Michael; Dafforn, Tim R. Share Save
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Targeting V1A-vasopressin receptors with [Arg6, D-Trp7,9, NmePhe8]-substance P (6-11) identifies a strategy to develop novel anti-cancer therapies MacKinnon, Alison C.; Tufail-Hanif, Uzma; Wheatley, Mark; Rossi, Adriano G.; Haslett, Christopher; Seckl, Michael; Sethi, Tariq Share Save
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Extracellular loops and ligand binding to a subfamily of Family A G-protein-coupled receptors Wheatley, M.; Simms, J.; Hawtin, S. R.; Wesley, V. J.; Wootten, D.; Conner, M.; Lawson, Z.; Conner, A. C.; Baker, A.; Cashmore, Y.; Kendrick, R.; Parslow, R. A. Share Save