Denis J. David - Publications, H-index & Citations

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Denis J. David

henri moissan

58H-index

270Paper Count

1.3WCitation Count

Published Papers 77

Publication Date

Prucalopride, a serotonin type 4 receptor agonist, induces fast anxiolytic/antidepressant effects and concomitant changes in the gut microbiota

npj Biofilms and Microbiomes

IF9.2

2026-02-04

OAAI

Sofia Cussotto; Salma R. Abdennebi; Isabelle Etting; Christine A. Denny; René Hen; Romain Colle; Emmanuelle Corruble; Jean-Claude Alvarez; Denis J. David; Indira Mendez-David

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Quantitative monitoring of ketamine’s impact on synaptic density using 11C-UCB-J PET imaging in the corticosterone mouse model of anxiety/depression

Molecular Psychiatry

IF10.1

2025-11-18

PREAI

Cassandre Corvo; Sébastien Goutal; Indira Mendez-David; Sarah Leterrier; Fabien Caille; Wadad Saba; Romain Colle; Emmanuelle Corruble; Vincent Lebon; Michel Bottlaender; Claire Leroy; Denis J. David; Nicolas Tournier

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Leveraging Fiber Photometry to Decipher Neural Circuits Underlying Anxiety in Mice

FUNDAMENTAL & CLINICAL PHARMACOLOGY

IF2.5

2025-10-01

OAAI

Abdennebi, Salma R.; Touihri, Nour El Haya; Corruble, Emmanuelle; David, Denis J.; Mendez-David, Indira

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A tale of two receptors: simultaneous targeting of NMDARs and 5-HT4Rs exerts additional effects against stress

Biological Psychiatry

IF9

2025-10-01

OAAI

Briana K. Chen; Michelle Jin; Gergely F. Turi; Victor M. Luna; Abhishek Shah; Taylor Moniz; Margaret E. Shannon; Michaela Pauers; Brenna L. Williams; Vananh Pham; Holly C. Hunsberger; Alain M. Gardier; Indira Mendez-David; Denis J. David; Christine A. Denny

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Altered Ventilation in Rats With Established Severe Monocrotaline-Induced Pulmonary Hypertension: The Role of the Dorsal Hypothalamus

Comprehensive Physiology

IF5.2

2025-09-24

OAAI

Aliaume Le Pape; Christophe Guignabert; Ly Tu; Nathalie Mougenot; Emma Burban; Denis David; Hugo Bottemanne; Emmanuelle Corruble; Thomas Similowski; Caroline Sevoz-Couche

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The Gut Microbiota Is Altered in Antidepressant-Free Depressed Patients and Is Associated With Depression Severity

Journal of Neurochemistry

IF4

2025-07-28

OAAI

Sofia Cussotto; Romain Colle; Cosmin S. Voican; Dragos M. Ciocan; Nicolas Trainel; Hugo Bottemanne; Yann Pelloux; Denis J. David; Anne-Marie Cassard; Gabriel Perlemuter; Emmanuelle Corruble

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Plasma kynurenine pathway metabolite levels increase in depressed patients after antidepressant treatment

brain behavior and immunity

IF0

2025-05-27

PREAI

Romain Colle; Kenneth Chappell; Khalil El Asmar; Bruno Fève; Philippe Chanson; Denis J. David; Céline Verstuyft; Laurent Becquemont; Emmanuelle Corruble

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Chronic, combinatorial targeting of NMDARs and 5-HT4Rs exerts extended behavioral effects against stress-induced perseverative behavior and hyponeophagia

NEUROPSYCHOPHARMACOLOGY

IF7.1

2025-04-01

PREAI

Chen, Briana K.; Whye, Alicia; Matthews, Louise C.; Moniz, Taylor; Mendez-David, Indira; Gardier, Alain M.; David, Denis J.; Johns, Stefanie; Weisblum, Eric; Denny, Christine A.

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Pharmacological Enhancement of Adult Hippocampal Neurogenesis Improves Behavioral Pattern Separation in Young and Aged Male Mice

BIOLOGICAL PSYCHIATRY: GLOBAL OPEN SCIENCE

IF3.7

2025-03-01

OAAI

Chang, Wei-li; Tegang, Karly; Samuels, Benjamin A.; Saxe, Michael; Wichmann, Juergen; David, Denis J.; David, Indira Mendez; Augustin, Angelique; Fischer, Holger; Golling, Sabrina; Lamerz, Jens; Roth, Doris; Graf, Martin; Zoffmann, Sannah; Santarelli, Luca; Jagasia, Ravi; Hen, Rene

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Synaptic Vesicle 2A (SV2A) Positron Emission Tomography (PET) Imaging as a Marker of Therapeutic Response in a Mouse Model of Depression

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE

IF3.7

2025-01-28

PREAI

Corvo, C; Mendez-David, I; Goutal, S; Saba, W; Bottlaender, M; Caillé, F; Hen, R; Colle, R; Corruble, E; Tournier, N; Leroy, C; David, DJ

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Habenular volume changes after venlafaxine treatment in patients with major depression

PSYCHIATRY AND CLINICAL NEUROSCIENCES

IF6.2

2024-06-12

OAAI

Etienne, Josselin; Boutigny, Alexandre; David, Denis J.; Deflesselle, Eric; Gressier, Florence; Becquemont, Laurent; Corruble, Emmanuelle; Colle, Romain

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Metabolomic profiles of 38 acylcarnitines in major depressive episodes before and after treatment

PSYCHOLOGICAL MEDICINE

IF5.5

2023-05-25

PREAI

Ait Tayeb, Abd El Kader; Colle, Romain; Chappell, Kenneth; El-Asmar, Khalil; Acquaviva-Bourdain, Cecile; David, Denis J.; Trabado, Severine; Chanson, Philippe; Feve, Bruno; Becquemont, Laurent; Verstuyft, Celine; Corruble, Emmanuelle

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Tobacco use is associated with low peripheral beta-arrestin 1 levels in major depression: A preliminary report

DRUG AND ALCOHOL DEPENDENCE

IF3.6

2022-11-01

OAAI

Mesdom, Pierre; Colle, Romain; Becquemont, Laurent; Chappell, Kenneth; David, Denis J.; Mendez-David, Indira; Corruble, Emmanuelle; Verstuyft, Celine

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The GG genotype of the serotonin 4 receptor genetic polymorphism, rs1345697, is associated with lower remission rates after antidepressant treatment: Findings from the METADAP cohort

JOURNAL OF AFFECTIVE DISORDERS

IF4.9

2022-02-01

OAAI

Poinsignon, Vianney; Colle, Romain; El Asmar, Khalil; Mendez-David, Indira; David, Denis J.; Tayeb, Abd El Kader Ait; Chappell, Kenneth; Gressier, Florence; Herrero, Hugo; Feve, Bruno; Becquemont, Laurent; Corruble, Emmanuelle; Verstuyft, Celine

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Plasma acetyl-l-carnitine and l-carnitine in major depressive episodes: a case-control study before and after treatment

PSYCHOLOGICAL MEDICINE

IF5.5

2021-10-14

PREAI

Tayeb, Abd El Kader Ait; Colle, Romain; El-Asmar, Khalil; Chappell, Kenneth; Acquaviva-Bourdain, Cecile; David, Denis J.; Trabado, Severine; Chanson, Philippe; Feve, Bruno; Becquemont, Laurent; Verstuyft, Celine; Corruble, Emmanuelle

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Peripheral tryptophan and serotonin and kynurenine pathways in major depression: A case-control study

EUROPEAN PSYCHIATRY

IF6.7

2021-08-13

OAAI

Colle, R.; Verstuyft, C.; David, D.; Chanson, P.; Corruble, E.

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Blood microbiota and metabolomic signature of major depression before and after antidepressant treatment: a prospective case-control study

JOURNAL OF PSYCHIATRY & NEUROSCIENCE

IF3.3

2021-05-01

OAAI

Ciocan, Dragos; Cassard, Anne-Marie; Becquemont, Laurent; Verstuyft, Celine; Voican, Cosmin Sebastian; El Asmar, Khalil; Colle, Romain; David, Denis; Trabado, Severine; Feve, Bruno; Chanson, Philippe; Perlemuter, Gabriel; Corruble, Emmanuelle

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The olfactory deficits of depressed patients are restored after remission with venlafaxine treatment

PSYCHOLOGICAL MEDICINE

IF5.5

2020-10-22

PREAI

Colle, Romain; El Asmar, Khalil; Verstuyft, Celine; Lledo, Pierre-Marie; Lazarini, Francoise; Chappell, Kenneth; Deflesselle, Eric; Tayeb, Abd El Kader Ait; Falissard, Bruno; Duron, Emmanuelle; Rotenberg, Samuel; Costemale-Lacoste, Jean-Francois; David, Denis J.; Gressier, Florence; Gardier, Alain M.; Hummel, Thomas; Becquemont, Laurent; Corruble, Emmanuelle

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Chronic Corticosterone Elevation Suppresses Adult Hippocampal Neurogenesis by Hyperphosphorylating Huntingtin

CELL REPORTS

IF6.9

2020-07-01

OAAI

Agasse, Fabienne; Mendez-David, Indira; Christaller, Wilhelm; Carpentier, Remi; Braz, Barbara Y.; David, Denis J.; Saudou, Frederic; Humbert, Sandrine

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Sex-specific neurobiological actions of prophylactic (R,S)-ketamine, (2R,6R)-hydroxynorketamine, and (2S,6S)-hydroxynorketamine

NEUROPSYCHOPHARMACOLOGY

IF7.1

2020-05-17

OAAI

Chen, Briana K.; Luna, Victor M.; LaGamma, Christina T.; Xu, Xiaoming; Deng, Shi-Xian; Suckow, Raymond F.; Cooper, Thomas B.; Shah, Abhishek; Brachman, Rebecca A.; Mendez-David, Indira; David, Denis J.; Gardier, Alain M.; Landry, Donald W.; Denny, Christine A.

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Research Directions