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SaveShare Save Share Save Share Save Constitutive activation and oncogenicity are mediated by loss of helical structure at the cytosolic boundary of thrombopoietin receptor mutant dimers
Defour, Jean-Philippe; Leroy, Emilie; Dass, Sharmila; Balligand, Thomas; Levy, Gabriel; Brett, Ian C.; Papadopoulos, Nicolas; Mouton, Celine; Genet, Lidvine; Pecquet, Christian; Staerk, Judith; Smith, Steven O.; Constantinescu, Stefan N.; Kay, Lewis E. Share Save Share Save Share Save Share Save Share Save Copper stabilizes antiparallel ?-sheet fibrils of the amyloid?40 (A?40)-Iowa variantCrooks, Elliot J.; Irizarry, Brandon A.; Ziliox, Martine; Kawakami, Toru; Victor, Tiffany; Xu, Feng; Hojo, Hironobu; Chiu, Kelley; Simmerling, Carlos; Van Nostrand, William E.; Smith, Steven O.; Miller, Lisa M. Share Save Share Save Share Save β-Sheet Structure within the Extracellular Domain of C99 Regulates Amyloidogenic ProcessingHu, Yi; Kienlen-Campard, Pascal; Tang, Tzu-Chun; Perrin, Florian; Opsomer, Remi; Decock, Marie; Pan, Xiaoshu; Octave, Jean-Noel; Constantinescu, Stefan N.; Smith, Steven O. Share Save Share Save Share Save Retinal orientation and interactions in rhodopsin reveal a two-stage trigger mechanism for activationKimata, Naoki; Pope, Andreyah; Eilers, Markus; Opefi, Chikwado A.; Ziliox, Martine; Hirshfeld, Amiram; Zaitseva, Ekaterina; Vogel, Reiner; Sheves, Mordechai; Reeves, Philip J.; Smith, Steven O. Share Save Share Save Share Save Share Save Presenilin Transmembrane Domain 8 Conserved AXXXAXXXG Motifs Are Required for the Activity of the γ-Secretase ComplexMarinangeli, Claudia; Tasiaux, Bernadette; Opsomer, Remi; Hage, Salim; Sodero, Alejandro O.; Dewachter, Ilse; Octave, Jean Noel; Smith, Steven O.; Constantinescu, Stefan N.; Kienlen-Campard, Pascal Share Save 
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