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M

Mohammad T. Mazhab‐Jafari

university health network

21H-index
72Paper Count
1.6KCitation Count
Published Papers 29
Publication Date
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Structural Change of ApoE–Lipid Nanoparticles Alters Receptor-Mediated Endocytosis and Induces Endosomal Disruption
errJournal of the American Chemical Society
IF15.6
err2026-02-19
err0
errOAAI
errYulin Mo; Heyi Liu; Alexander F. A. Keszei; David L. Dai; Ali Makky; Lili Ding; Anni Pan; Jiachuan Bu; Mohammad T. Mazhab-Jafari; Juan Chen; Gang Zheng
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Allosteric regulation of fungal fatty acid synthesis
errStructure
IF4.3
err2025-10-02
err0
PREAI
errS. M. Naimul Hasan; Elnaz Khalili Samani; Alexander F.A. Keszei; Mahtab Heydari; Mohammad T. Mazhab-Jafari
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Author Correction: Structures of KEOPS bound to tRNA reveal functional roles of the kinase Bud32
errNature Communications
IF15.7
err2025-07-24
err0
errOAAI
errSamara Mishelle Ona Chuquimarca; Jonah Beenstock; Salima Daou; Jennifer Porat; Alexander F. A. Keszei; Jay Z. Yin; Tobias Beschauner; Mark A. Bayfield; Mohammad T. Mazhab-Jafari; Frank Sicheri
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Cryo-EM of AKAP350/AKAP9 Reveals Fibrillar Clusters and an Association With DNA
errJOURNAL OF MOLECULAR BIOLOGY
IF4.5
err2025-06-01
err0
PREAI
errDai, David L.; Keszei, Alexander F. A.; Kolobova, Elena; St-Germain, Jonathan; Hasan, S. M. Naimul; Liu, Alex C. H.; Zhang, Xu; Raught, Brian; Goldenring, James R.; Mazhab-Jafari, Mohammad T.
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Structures of KEOPS bound to tRNA reveal functional roles of the kinase Bud32
errNATURE COMMUNICATIONS
IF15.7
err2024-12-05
err0
errOAAI
errChuquimarca, Samara Mishelle Ona; Beenstock, Jonah; Daou, Salima; Porat, Jennifer; Keszei, Alexander F. A.; Yin, Jay Z.; Beschauner, Tobias; Bayfield, Mark A.; Mazhab-Jafari, Mohammad T.; Sicheri, Frank
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Structure and dynamics of a pentameric KCTD5/CUL3/Gβγ E3 ubiquitin ligase complex
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-04-16
err3
errOAAI
errNguyen, Duc Minh; Rath, Deanna H.; Devost, Dominic; Petrin, Darlaine; Rizk, Robert; Ji, Alan X.; Narayanan, Naveen; Yong, Darren; Zhai, Andrew; Kuntz, Douglas A.; Mian, Maha U. Q.; Pomroy, Neil C.; Keszei, Alexander F. A.; Benlekbir, Samir; Mazhab-Jafari, Mohammad T.; Rubinstein, John L.; Hebert, Terence E.; Prive, Gilbert G.
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Serine phosphorylation marks proteins for degradation by the mitochondrial matrix protease, ClpXP
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errFeng, Yue; Goncalves, Monica M.; Jitkova, Yulia; Keszei, Alexander; Sarathy, Chaitra; Trudel, Vincent; St-Germain, Jonathan; Tcheng, Matthew; Yan, Yongran; Hurren, Rose; Schultz, Matthew; Raught, Brian; Yudin, Andrei; Mazhab-Jafari, Mohammad; Vahidi, Siavash; Schimmer, Aaron D.
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Direct structural analysis of a single acyl carrier protein domain in fatty acid synthase from the fungus Saccharomyces cerevisiae
errCOMMUNICATIONS BIOLOGY
IF5.1
err2024-01-12
err1
errOAAI
errSamani, Elnaz Khalili; Chen, Amy C.; Lou, Jennifer W.; Dai, David L.; Keszei, Alexander F. A.; Tan, Guihong; Boone, Charles; Grininger, Martin; Mazhab-Jafari, Mohammad T.
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Identification of triazenyl indoles as inhibitors of fungal fatty acid biosynthesis with broad-spectrum activity
errCELL CHEMICAL BIOLOGY
IF7.2
err2023-07-01
err9
errOAAI
errIyer, Kali R.; Li, Sheena C.; Revie, Nicole M.; Lou, Jennifer W.; Duncan, Dustin; Fallah, Sara; Sanchez, Hiram; Skulska, Iwona; Usaj, Mojca Mattiazzi; Safizadeh, Hamid; Larsen, Brett; Wong, Cassandra; Aman, Ahmed; Kiyota, Taira; Yoshimura, Mami; Kimura, Hiromi; Hirano, Hiroyuki; Yoshida, Minoru; Osada, Hiroyuki; Gingras, Anne -Claude; Andes, David R.; Shapiro, Rebecca S.; Robbins, Nicole; Mazhab-Jafari, Mohammad T.; Whitesell, Luke; Yashiroda, Yoko; Yashiroda, Yoko; Boone, Charles; Cowen, Leah E.
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Atomic model for core modifying region of human fatty acid synthase in complex with Denifanstat
errNATURE COMMUNICATIONS
IF15.7
err2023-06-12
err4
errOAAI
errHasan, S. M. Naimul; Lou, Jennifer W. W.; Keszei, Alexander F. A.; Dai, David L. L.; Mazhab-Jafari, Mohammad T. T.
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Structure of the immunoregulatory sialidase NEU1
errSCIENCE ADVANCES
IF12.5
err2023-05-19
err15
errOAAI
errGorelik, Alexei; Illes, Katalin; Mazhab-Jafari, Mohammad T.; Nagar, Bhushan
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errSave
Mitochondrial ClpXP degrades serine phosphorylated protein aggregates
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errFeng, Yue; Jitkova, Yulia; Keszei, Alexander; St-Germain, Jonathan; Yan, Yongran; Raught, Brian; Mazhab-Jafari, Mohammad; Schimmer, Aaron
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errSave
The Trisubstituted Isoxazole MMV688766 Exerts Broad-Spectrum Activity against Drug-Resistant Fungal Pathogens through Inhibition of Lipid Homeostasis
errMBIO
IF4.7
err2022-12-20
err5
errOAAI
errPuumala, Emily; Zaslaver, Olga; Chen, Amy; Duncan, Dustin; Fogal, Meea; Shapiro, Rebecca S.; Mazhab-Jafari, Mohammad T.; Whitesell, Luke; Montenegro-Burke, J. Rafael; Robbins, Nicole; Cowen, Leah E.
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SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2022-07-25
err38
errOAAI
errXu, Zhang; Choi, Jung-Hyun; Dai, David L.; Luo, Jun; Ladak, Reese Jalal; Li, Qian; Wang, Yimeng; Zhang, Christine; Wiebe, Shane; Liu, Alex C. H.; Ran, Xiaozhuo; Yang, Jiaqi; Naeli, Parisa; Garzia, Aitor; Zhou, Lele; Mahmood, Niaz; Deng, Qiyun; Elaish, Mohamed; Lin, Rongtuan; Mahal, Lara K.; Hobman, Tom C.; Pelletier, Jerry; Alain, Tommy; Vidal, Silvia M.; Duchaine, Thomas; Mazhab-Jafari, Mohammad T.; Mao, Xiaojuan; Jafarnejad, Seyed Mehdi; Sonenberg, Nahum
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Structure of the murine lysosomal multienzyme complex core
errSCIENCE ADVANCES
IF12.5
err2021-05-14
err12
errOAAI
errGorelik, Alexei; Illes, Katalin; Hasan, S. M. Naimul; Nagar, Bhushan; Mazhab-Jafari, Mohammad T.
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errSave
Steric occlusion regulates proximal interactions of acyl carrier protein domain in fungal fatty acid synthase
errCOMMUNICATIONS BIOLOGY
IF5.1
err2020-05-29
err8
errOAAI
errLou, Jennifer W.; Mazhab-Jafari, Mohammad T.
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Electron cryomicroscopy observation of acyl carrier protein translocation in type I fungal fatty acid synthase
errSCIENTIFIC REPORTS
IF3.9
err2019-09-10
err21
errOAAI
errLou, Jennifer W.; Iyer, Kali R.; Hasan, S. M. Naimul; Cowen, Leah E.; Mazhab-Jafari, Mohammad T.
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errSave
Molecular basis of human CD22 function and therapeutic targeting
errNATURE COMMUNICATIONS
IF15.7
err2017-10-02
err122
errOAAI
errEreno-Orbea, June; Sicard, Taylor; Cui, Hong; Mazhab-Jafari, Mohammad T.; Benlekbir, Samir; Guarne, Alba; Rubinstein, John L.; Julien, Jean-Philippe
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Biochemical Classification of Disease-associated Mutants of RAS-like Protein Expressed in Many Tissues (RIT1)
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2016-07-01
err17
errOAAI
errFang, Zhenhao; Marshall, Christopher B.; Yin, Jiani C.; Mazhab-Jafari, Mohammad T.; Gasmi-Seabrook, Genevieve M. C.; Smith, Matthew J.; Nishikawa, Tadateru; Xu, Yang; Neel, Benjamin G.; Ikura, Mitsuhiko
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errSave
Cryo-EM studies of the structure and dynamics of vacuolar-type ATPases
errSCIENCE ADVANCES
IF12.5
err2016-07-01
err18
errOAAI
errMazhab-Jafari, Mohammad T.; Rubinstein, John L.
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
N
Nahum Sonenberg
H-index: 178 · Papers: 957
B
Benjamin G. Neel
H-index: 120 · Papers: 605
M
Minoru Yoshida
H-index: 115 · Papers: 1.9K
A
Anne‐Claude Gingras
H-index: 114 · Papers: 632
D
David R. Andes
H-index: 110 · Papers: 596
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