Not logged inModifying the glycosylation profile of SARS-CoV-2 spike-based subunit vaccines alters focusing of the humoral immune response in a mouse model
Renner, Tyler M.; Stuible, Matthew; Rossotti, Martin A.; Rohani, Nazanin; Cepero-Donates, Yuneivy; Sauvageau, Janelle; Deschatelets, Lise; Dudani, Renu; Harrison, Blair A.; Baardsnes, Jason; Koyuturk, Izel; St. Michael, Frank; Hill, Jennifer J.; Hemraz, Usha D.; Lenferink, Anne E. G.; Tanha, Jamshid; Fernandes, Barbara; Roldao, Antonio; McCluskie, Michael J.; Akache, Bassel; Durocher, Yves .png)
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SaveShare Save TNX-1500, a crystallizable fragment-modified anti-CD154 antibody, prolongs nonhuman primate renal allograft survivalLassiter, Grace; Otsuka, Ryo; Hirose, Takayuki; Rosales, Ivy; Karadagi, Ahmad; Tomosugi, Toshihide; Dehnadi, Abbas; Lee, Hang; Colvin, Robert B.; Baardsnes, Jason; Moraitis, Anna; Smith, Emma E.; Ali, Zahida; Berhe, Phil; Mulder, Andrew; Meibohm, Bernd; Daugherty, Bruce; Fogarty, Siobhan; Pierson, Richard N.; Lederman, Seth; Kawai, Tatsuo Share Save Tuning the immune response: sulfated archaeal glycolipid archaeosomes as an effective vaccine adjuvant for induction of humoral and cell-mediated immunity towards the SARS-CoV-2 Omicron variant of concernRenner, Tyler M.; Akache, Bassel; Stuible, Matthew; Rohani, Nazanin; Cepero-Donates, Yuneivy; Deschatelets, Lise; Dudani, Renu; Harrison, Blair A.; Baardsnes, Jason; Koyuturk, Izel; Hill, Jennifer J.; Hemraz, Usha D.; Regnier, Sophie; Lenferink, Anne E. G.; Durocher, Yves; McCluskie, Michael J. Share Save A CHO stable pool production platform for rapid clinical development of trimeric SARS-CoV-2 spike subunit vaccine antigensJoubert, Simon; Stuible, Matthew; Lord-Dufour, Simon; Lamoureux, Linda; Vaillancourt, Francois; Perret, Sylvie; Ouimet, Manon; Pelletier, Alex; Bisson, Louis; Mahimkar, Rohan; Pham, Phuong Lan; L'Ecuyer-Coelho, Helene; Roy, Marjolaine; Voyer, Robert; Baardsnes, Jason; Sauvageau, Janelle; St-Michael, Frank; Robotham, Anna; Kelly, John; Acel, Andrea; Schrag, Joseph D.; El Bakkouri, Majida; Durocher, Yves Share Save An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicityWeisser, Nina E.; Sanches, Mario; Escobar-Cabrera, Eric; O'Toole, Jason; Whalen, Elizabeth; Chan, Peter W. Y.; Wickman, Grant; Abraham, Libin; Choi, Kate; Harbourne, Bryant; Samiotakis, Antonios; Rojas, Andrea Hernandez; Volkers, Gesa; Wong, Jodi; Atkinson, Claire E.; Baardsnes, Jason; Worrall, Liam J.; Browman, Duncan; Smith, Emma E.; Baichoo, Priya; Cheng, Chi Wing; Guedia, Joy; Kang, Sohyeong; Mukhopadhyay, Abhishek; Newhook, Lisa; Ohrn, Anders; Raghunatha, Prajwal; Zago-Schmitt, Matteo; Schrag, Joseph D.; Smith, Joel; Zwierzchowski, Patricia; Scurll, Joshua M.; Fung, Vincent; Black, Sonia; Strynadka, Natalie C. J.; Gold, Michael R.; Presta, Leonard G.; Ng, Gordon; Dixit, Surjit Share Save Production of afucosylated antibodies in CHO cells by coexpression of an anti-FUT8 intrabodyJoubert, Simon; Guimond, Julie; Perret, Sylvie; Malenfant, Felix; Elahi, S. Mehdy; Marcil, Anne; Parat, Marie; Gilbert, Michel; Lenferink, Anne E. G.; Baardsnes, Jason; Durocher, Yves Share Save Hydrogen-deuterium exchange mass spectrometry reveals three unique binding responses of mAbs directed to the catalytic domain of hCAIXSheff, Joey G.; Kelly, John F.; Robotham, Anna; Sulea, Traian; Malenfant, Felix; L'Abbe, Denis; Duchesne, Melanie; Pelletier, Alex; Lefebvre, Jean; Acel, Andrea; Parat, Marie; Gosselin, Mylene; Wu, Cunle; Fortin, Yves; Baardsnes, Jason; Van Faassen, Henk; Awrey, Shannon; Chafe, Shawn C.; McDonald, Paul C.; Dedhar, Shoukat; Lenferink, Anne E. G. Share Save Isolation and characterization of monoclonal antibodies against human carbonic anhydrase-IXLenferink, Anne E. G.; McDonald, Paul C.; Cantin, Christiane; Grothe, Suzanne; Gosselin, Mylene; Baardsnes, Jason; Banville, Myriam; Lachance, Paul; Robert, Alma; Cepero-Donates, Yuneivy; Radinovic, Stevo; Salois, Patrick; Parat, Marie; Oamari, Hafida; Dulude, Annie; Patel, Mehul; Lafrance, Martin; Acel, Andrea; Bousquet-Gagnon, Nathalie; L'Abbe, Denis; Pelletier, Alex; Malenfant, Felix; Jaramillo, Maria; O'Connor-Mccourt, Maureen; Wu, Cunle; Durocher, Yves; Duchesne, Melanie; Gadoury, Christine; Marcil, Anne; Fortin, Yves; Paul-Roc, Beatrice; Acchione, Maurizio; Chafe, Shawn C.; Nemirovsky, Oksana; Lau, Joseph; Benard, Francois; Dedhar, Shoukat Share Save Redesigning an antibody H3 loop by virtual screening of a small library of human germline-derived sequencesCorbeil, Christopher R.; Manenda, Mahder Seifu; Sulea, Traian; Baardsnes, Jason; Picard, Marie-Eve; Hogues, Herve; Gaudreault, Francis; Deprez, Christophe; Shi, Rong; Purisima, Enrico O. Share Save New soluble angiopoietin analog of Hepta-ANG1 prevents pathological vascular leakageLiu, Pan; Ryczko, Michael; Xie, Xinfang; Baardsnes, Jason; Lord-Dufour, Simon; Duroche, Yves; Hicks, Emily Anne; Taiyab, Aftab; Sheardown, Heather; Quaggin, Susan E.; Jin, Jing Share Save AlbuCORE: an albumin-based molecular scaffold for multivalent biologics designSanches, Mario; D'Angelo, Igor; Jaramillo, Maria; Baardsnes, Jason; Zwaagstra, John; Schrag, Joe; Schoenhofen, Ian; Acchione, Mauro; Lawn, Sam; Wickman, Grant; Weisser, Nina; Poon, David K. Y.; Ng, Gordon; Dixit, Surjit Share Save Structure-based engineering of pH-dependent antibody binding for selective targeting of solid-tumor microenvironmentSulea, Traian; Rohani, Nazanin; Baardsnes, Jason; Corbeil, Christopher R.; Deprez, Christophe; Cepero-Donates, Yuneivy; Robert, Alma; Schrag, Joseph D.; Parat, Marie; Duchesne, Melanie; Jaramillo, Maria L.; Purisima, Enrico O.; Zwaagstra, John C. Share Save Binding symmetry and surface flexibility mediate antibody self-associationSchrag, Joseph D.; Picard, Marie-Eve; Gaudreault, Francis; Gagnon, Louis-Patrick; Baardsnes, Jason; Manenda, Mahder S.; Sheff, Joey; Deprez, Christophe; Baptista, Cassio; Hogues, Herve; Kelly, John F.; Purisima, Enrico O.; Shi, Rong; Sulea, Traian Share Save Enhanced anti-metastatic bioactivity of an IGF-TRAP re-engineered to improve physicochemical propertiesVaniotis, George; Moffett, Serge; Sulea, Traian; Wang, Ni; Elahi, S. Mehdy; Lessard, Etienne; Baardsnes, Jason; Perrino, Stephanie; Durocher, Yves; Frystyk, Jan; Massie, Bernard; Brodt, Pnina Share Save Share Save A Novel Affinity Tag, ABTAG, and Its Application to the Affinity Screening of Single-Domain Antibodies Selected by Phage DisplayHussack, Greg; Baral, Toya Nath; Baardsnes, Jason; van Faassen, Henk; Raphael, Shalini; Henry, Kevin A.; Zhang, Jianbing; MacKenzie, C. Roger Share Save Share Save Development of AVID200, a novel TGF-β targeting immunotherapy: Characterization of immunomodulatory effectsO'Connor-McCourt, M.; Lenferink, A.; Zwaagstra, J.; Sulea, T.; Weeratna, R.; Maleki, S.; Baardsnes, J.; Collins, C.; Cantin, C.; Durocher, Y.; Singh, R.; Figueredo, R.; Krishnan, L.; Koropatnick, J.; Tikhomirov, I. Share Save Share Save 
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