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Alexander G. Sorets

vanderbilt university

8H-index
23Paper Count
402Citation Count
Published Papers 9
Publication Date
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Intravenous lipid-siRNA conjugate mediates gene silencing at the blood-brain barrier and blood-CSF barrier
errJournal of Controlled Release
IF11.5
err2025-09-11
err0
errOAAI
errAlexander G. Sorets; Katrina R. Schwensen; Nora Francini; Andrew Kjar; Sarah Lyons; Joshua C. Park; Dillon Palmer; Adam M. Abdulrahman; Rebecca P. Cowell; Ketaki A. Katdare; Ella N. Hoogenboezem; Angela Wang; Alexander P. Ligocki; Rebecca J. Embalabala; Neil Dani; Craig L. Duvall; Ethan S. Lippmann
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errSave
Elucidating brain transport pathways and cell type-dependent gene silencing of a durable lipid-siRNA conjugate administered into cerebrospinal fluid
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-07-08
err2
errOAAI
errSorets, Alexander G.; Schwensen, Katrina R.; Francini, Nora; Kjar, Andrew; Abdulrahman, Adam M.; Shostak, Alena; Katdare, Ketaki A.; Schoch, Kathleen M.; Cowell, Rebecca P.; Park, Joshua C.; Ligocki, Alexander P.; Ford, William T.; Ventura-Antunes, Lissa; Hoogenboezem, Ella N.; Prusky, Alex; Castleberry, Mark; Michell, Danielle L.; Fritsch, Emma; Lyons, Sarah M.; Miller, Timothy M.; Vickers, Kasey C.; Schrag, Matthew S.; Duvall, Craig L.; Lippmann, Ethan S.
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errSave
siRNA conjugate with high albumin affinity and degradation resistance for delivery and treatment of arthritis in mice and guinea pigs
errNATURE BIOMEDICAL ENGINEERING
IF26.6
err2025-05-16
err0
errOAAI
errColazo, Juan M.; Keech, Megan C.; Shah, Veeraj; Hoogenboezem, Ella N.; Lo, Justin H.; Francini, Nora; Cassidy, Nina T.; Yu, Fang; Sorets, Alexander G.; Mccune, Joshua T.; Dejulius, Carlisle R.; Cho, Hongsik; Michell, Danielle L.; Vickers, Kacey C.; Gibson-Corley, Katherine N.; Hasty, Karen A.; Crofford, Leslie J.; Cook, Rebecca S.; Duvall, Craig L.
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IQGAP2 regulates blood-brain barrier immune dynamics
errISCIENCE
IF4.1
err2025-03-01
err0
errOAAI
errKatdare, Ketaki A.; Kjar, Andrew; O'Brown, Natasha M.; Neal, Emma H.; Sorets, Alexander G.; Shostak, Alena; Romero-Fernandez, Wilber; Kwiatkowski, Alexander J.; Mlouk, Kate; Kim, Hyosung; Cowell, Rebecca P.; Schwensen, Katrina R.; Tapia, Cristian O. Carvajal; Venslovaite, Guste; Horner, Kensley B.; Wilson, John T.; Schrag, Matthew S.; Megason, Sean G.; Lippmann, Ethan S.
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errSave
Fabrication of endothelialized capillary-like microchannel networks using sacrificial thermoresponsive microfibers
errBIOFABRICATION
IF8
err2024-11-19
err0
PREAI
errRector, John A.; Mcbride, Lucas; Weber, Callie M.; Grossman, Kira; Sorets, Alexander; Ventura-Antunes, Lissa; Holtz, Isabella; Young, Katherine; Schrag, Matthew; Lippmann, Ethan S.; Bellan, Leon M.
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errSave
Core polymer optimization of ternary siRNA nanoparticles enhances in vivo safety, pharmacokinetics, and tumor gene silencing
errBIOMATERIALS
IF12.9
err2023-06-01
err11
errOAAI
errPatel, Shrusti S.; Hoogenboezem, Ella N.; Yu, Fang; DeJulius, Carlisle R.; Fletcher, R. Brock; Sorets, Alex G.; Cherry, Fiona K.; Lo, Justin H.; Bezold, Mariah G.; Francini, Nora; d'Arcy, Richard; Brasuell, Jordan E.; Cook, Rebecca S.; Duvall, Craig L.
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errSave
Therapeutic silencing of Rictor using siRNA nanoparticles to selectively block mTORC2 signaling in triple negative breast cancer
errCANCER RESEARCH
IF16.6
err2023-04-04
err1
PREAI
errPatel, Shrusti S.; Hoogenboezem, Ella N.; Yu, Fang; Sorets, Alex G.; Cherry, Fiona K.; Lo, Justin H.; Francini, Nora; d'Arcy, Richard A.; Cook, Rebecca S.; Duvall, Craig L.
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errSave
Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin
errNATURE COMMUNICATIONS
IF15.7
err2022-11-02
err62
errOAAI
errKim, Hyosung; Leng, Kun; Park, Jinhee; Sorets, Alexander G.; Kim, Suil; Shostak, Alena; Embalabala, Rebecca J.; Mlouk, Kate; Katdare, Ketaki A.; Rose, Indigo V. L.; Sturgeon, Sarah M.; Neal, Emma H.; Ao, Yan; Wang, Shinong; Sofroniew, Michael, V; Brunger, Jonathan M.; McMahon, Douglas G.; Schrag, Matthew S.; Kampmann, Martin; Lippmann, Ethan S.
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errSave
Caveolae-mediated transport at the injured blood-brain barrier as an underexplored pathway for central nervous system drug delivery
errCURRENT OPINION IN CHEMICAL ENGINEERING
IF6.8
err2020-12-01
err14
errOAAI
errSorets, Alexander G.; Rosch, Jonah C.; Duvall, Craig L.; Lippmann, Ethan S.
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
W
W. T. Ford
H-index: 155 · Papers: 3.2K
M
Michael V. Sofroniew
H-index: 98 · Papers: 247
T
Timothy M. Miller
H-index: 63 · Papers: 310
M
Martin Kampmann
H-index: 57 · Papers: 237
D
Douglas G. McMahon
H-index: 50 · Papers: 174
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