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J

Jingxu Guo

University of Cambridge

13H-index
34Paper Count
776Citation Count
Published Papers 15
Publication Date
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Endoglin as a BMP9 co-receptor in vascular endothelial cells: prodomain displacement and TGFBRII recruitment
errNature Communications
IF15.7
err2025-12-31
err0
errOAAI
errJingxu Guo; Karolina Kostrzyńska; Ioannis Kamzolas; Xudong Yang; Midory Thorikay; Eckart De Bie; Rowena J. Jones; Adam Brownstein; Lu Long; Christopher J. Rhodes; Allan Lawrie; Martin R. Wilkins; Esmee Groeneveld; Zhen Tong; Marie-José Goumans; Evangelia Petsalaki; Jason Hong; Mark R. Toshner; Antonio Vidal-Puig; Helen M. Arthur; Wei Li
errShare
errSave
Distinct signalling dynamics of BMP4 and BMP9 in brown versus white adipocytes
errSCIENTIFIC REPORTS
IF3.9
err2025-05-08
err0
errOAAI
errConstant, Benjamin; Kamzolas, Ioannis; Yang, Xudong; Guo, Jingxu; Rodriguez-Fdez, Sonia; Mali, Iman; Rodriguez-Cuenca, Sergio; Petsalaki, Evangelia; Vidal-Puig, Antonio; Li, Wei
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errSave
INVESTIGATING THE THERAPEUTIC POTENTIAL OF RECOMBINANT BMP10 IN A MOUSE MODEL OF HEREDITARY HAEMORRHAGIC TELANGIECTASIA
errHEART
IF4.4
err2023-06-02
err0
errOAAI
errKostrzynska, Karolina; Yang, XuDong; Guo, Jingxu; Moore, Stephen; Morrell, Nick; Arthur, Helen M.; Li, Wei
errShare
errSave
Autoimmunity Is a Significant Feature of Idiopathic Pulmonary Arterial Hypertension
errAMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
err2022-07-01
err18
errOAAI
errJones, Rowena J.; De Bie, Eckart M. D. D.; Groves, Emily; Zalewska, Kasia, I; Swietlik, Emilia M.; Treacy, Carmen M.; Martin, Jennifer M.; Polwarth, Gary; Li, Wei; Guo, Jingxu; Baxendale, Helen E.; Coleman, Stephen; Savinykh, Natalia; Coghlan, J. Gerry; Corris, Paul A.; Howard, Luke S.; Johnson, Martin K.; Church, Colin; Kiely, David G.; Lawrie, Allan; Lordan, James L.; Ross, Robert V. Mackenzie; Zaba, Joanna Pepke; Wilkins, Martin R.; Wort, S. John; Fiorillo, Edoardo; Orru, Valeria; Cucca, Francesco; Rhodes, Christopher J.; Graf, Stefan; Morrell, Nicholas W.; McKinney, Eoin F.; Wallace, Chris; Toshner, Mark
errShare
errSave
Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP10
errNATURE COMMUNICATIONS
IF15.7
err2022-05-03
err7
errOAAI
errGuo, Jingxu; Liu, Bin; Thorikay, Midory; Yu, Minmin; Li, Xiaoyan; Tong, Zhen; Salmon, Richard M.; Read, Randy J.; ten Dijke, Peter; Morrell, Nicholas W.; Li, Wei
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errSave
Molecular basis of ALK1-mediated signalling by BMP9/BMP10 and their prodomain-bound forms
errNATURE COMMUNICATIONS
IF15.7
err2020-04-01
err52
errOAAI
errSalmon, Richard M.; Guo, Jingxu; Wood, Jennifer H.; Tong, Zhen; Beech, John S.; Lawera, Aleksandra; Yu, Minmin; Grainger, David J.; Reckless, Jill; Morrell, Nicholas W.; Li, Wei
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errSave
Characterization of GDF2 Mutations and Levels of BMP9 and BMP10 in Pulmonary Arterial Hypertension
errAMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
err2020-03-01
err87
errOAAI
errHodgson, Joshua; Swietlik, Emilia M.; Salmon, Richard M.; Hadinnapola, Charaka; Nikolic, Ivana; Wharton, John; Guo, Jingxu; Liley, James; Haimel, Matthias; Bleda, Marta; Southgate, Laura; Machado, Rajiv D.; Martin, Jennifer M.; Treacy, Carmen M.; Yates, Katherine; Daugherty, Louise C.; Shamardina, Olga; Whitehorn, Deborah; Holden, Simon; Bogaard, Harm J.; Church, Colin; Coghlan, Gerry; Condliffe, Robin; Corris, Paul A.; Danesino, Cesare; Eyries, Melanie; Gall, Henning; Ghio, Stefano; Ghofrani, Hossein-Ardeschir; Gibbs, J. Simon R.; Girerd, Barbara; Houweling, Arjan C.; Howard, Luke; Humbert, Marc; Kiely, David G.; Kovacs, Gabor; Lawrie, Allan; Ross, Robert V. MacKenzie; Moledina, Shahin; Montani, David; Olschewski, Andrea; Olschewski, Horst; Ouwehand, Willem H.; Peacock, Andrew J.; Pepke-Zaba, Joanna; Prokopenko, Inga; Rhodes, Christopher J.; Scelsi, Laura; Seeger, Werner; Soubrier, Florent; Suntharalingam, Jay; Toshner, Mark R.; Trembath, Richard C.; Noordegraaf, Anton Vonk; Wort, Stephen J.; Wilkins, Martin R.; Yu, Paul B.; Li, Wei; Graef, Stefan; Upton, Paul D.; Morrell, Nicholas W.
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errSave
In crystallo-screening for discovery of human norovirus 3C-like protease inhibitors
errJOURNAL OF STRUCTURAL BIOLOGY-X
IF5.1
err2020-01-01
err3
errOAAI
errGuo, Jingxu; Douangamath, Alice; Song, Weixiao; Coker, Alun R.; Chan, A. W. Edith; Wood, Steve P.; Cooper, Jonathan B.; Resnick, Efrat; London, Nir; von Delft, Frank
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errSave
A Bone Morphogenetic Protein (BMP)-derived Peptide Based on the Type I Receptor-binding Site Modifies Cell-type Dependent BMP Signalling
errSCIENTIFIC REPORTS
IF3.9
err2019-09-17
err23
errOAAI
errTong, Zhen; Guo, Jingxu; Glen, Robert C.; Morrell, Nicholas W.; Li, Wei
errShare
errSave
Advances in the molecular regulation of endothelial BMP9 signalling complexes and implications for cardiovascular disease
errBIOCHEMICAL SOCIETY TRANSACTIONS
IF4.3
err2019-05-24
err16
errOAAI
errWood, Jennifer H.; Guo, Jingxu; Morrell, Nicholas W.; Li, Wei
errShare
errSave
Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2019-05-07
err225
errOAAI
errResnick, Efrat; Bradley, Anthony; Gan, Jinrui; Douangamath, Alice; Krojer, Tobias; Sethi, Ritika; Geurink, Paul P.; Aimon, Anthony; Amitai, Gabriel; Bellini, Dom; Bennett, James; Fairhead, Michael; Fedorov, Oleg; Gabizon, Ronen; Gan, Jin; Gu, Jingxu; Plotnikov, Alexander; Reznik, Nava; Ruda, Gian Filippo; Diaz-Saez, Laura; Straub, Verena M.; Szommer, Tamas; Velupillai, Srikannathasan; Zaidman, Daniel; Zhang, Yanling; Coker, Alun R.; Dowson, Christopher G.; Barr, Haim M.; Wang, Chu; Huber, Kilian V. M.; Brennan, Paul E.; Ovaa, Huib; von Delft, Frank; London, Nir
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errSave
Increased Antielastase Activity in Idiopathic Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension
errAMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
IF5.3
err2018-11-01
err1
errOAAI
errGuo, Jingxu; Lodge, Katharine; Newnham, Michael; Bunclark, Katherine; Toshner, Mark; Morrell, Nicholas W.; Li, Wei
errShare
errSave
Frutapin, a lectin from Artocarpus incisa (breadfruit): cloning, expression and molecular insights
errBIOSCIENCE REPORTS
IF4.7
err2017-07-21
err5
errOAAI
errde Sousa, Felipe Domingos; da Silva, Bruno Bezerra; Furtado, Gilvan Pessoa; Carneiro, Igor de Sa; Pinto Lobo, Marina Duarte; Guan, Yiwei; Guo, Jingxu; Coker, Alun R.; Lourenzoni, Marcos Roberto; Florindo Guedes, Maria Izabel; Owen, James S.; Abraham, David J.; de Oliveira Monteiro-Moreira, Ana Cristina; Moreira, Renato de Azevedo
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errSave
Structure of a Kunitz-type potato cathepsin D inhibitor (vol 192, pg 554, 2015)
errJOURNAL OF STRUCTURAL BIOLOGY
IF5.1
err2016-02-01
err0
PREAI
errGuo, Jingxu; Erskine, Peter T.; Coker, Alun R.; Wood, Steve P.; Cooper, Jonathan B.; Mares, Michael; Baudys, Miroslav
errShare
errSave
Structure of a Kunitz-type potato cathepsin D inhibitor
errJOURNAL OF STRUCTURAL BIOLOGY
IF5.1
err2015-12-01
err15
PREAI
errGuo, Jingxu; Erskine, Peter T.; Coker, Alun R.; Wood, Steve P.; Cooper, Jonathan B.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
M
Marc Humbert
H-index: 177 · Papers: 2.2K
P
Peter ten Dijke
H-index: 147 · Papers: 794
W
Werner Seeger
H-index: 130 · Papers: 2.4K
W
Willem H. Ouwehand
H-index: 128 · Papers: 561
H
Hossein Ardeschir Ghofrani
H-index: 120 · Papers: 1.2K
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