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A modular mRNA vaccine platform encoding antigen-presenting capsid virus-like particles enhances the immunogenicity of the malaria antigen Pfs25 Fougeroux, Cyrielle; Hagen, Sven Hendrik; Goksoyr, Louise; Aves, Kara-Lee; Okholm, Anna Kathrine; Morin, Candice; Lokras, Abhijeet Girish; Baghel, Saahil Sandeep; Foged, Camilla; van de Vegte-bolmer, Marga; van Gemert, Geert-Jan; Jore, Matthijs M.; Vidal-Calvo, Elena Ethel; Gustavsson, Tobias; Salanti, Ali; Theander, Thor Grundtvig; Nielsen, Morten Agertoug; de Jongh, Willem Adriaan; Bertelsen, Adam Frederik Sander Share Save
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Molecular properties and diagnostic potential of monoclonal antibodies targeting cytotoxic α-synuclein oligomers Nielsen, Janni; Lauritsen, Johanne; Pedersen, Jannik N.; Nowak, Jan S.; Bendtsen, Malthe K.; Kleijwegt, Giulia; Lusser, Kaija; Pitarch, Laia C.; Moreno, Julian V.; Schneider, Matthias M.; Krainer, Georg; Goksoyr, Louise; Khalife, Paul; Kaalund, Sanne Simone; Aznar, Susana; Kjaergaard, Magnus; Sereikaite, Vita; Stromgaard, Kristian; Knowles, Tuomas P. J.; Nielsen, Morten Agertoug; Sander, Adam F.; Romero-Ramos, Marina; Otzen, Daniel E. Share Save
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Aotus nancymaae model predicts human immune response to the placental malaria vaccine candidate VAR2CSA Doritchamou, Justin; Nielsen, Morten A.; Chene, Arnaud; Viebig, Nicola K.; Lambert, Lynn E.; Sander, Adam F.; Semblat, Jean-Philippe; Hundt, Sophia; Orr-Gonzalez, Sachy; Janitzek, Christoph Mikkel; Spiegel, Alicia J.; Clemmensen, Stine B.; Thomas, Marvin L.; Nason, Martha C.; Snow-Smith, Maryonne; Barnafo, Emma K.; Shiloach, Joseph; Chen, Beth B.; Nadakal, Steven; Highsmith, Kendrick; Ouahes, Tarik; Conteh, Solomon; Sharma, Ankur; Torano, Holly; Butler, Brandi; Reiter, Karine; Rausch, Kelly M.; Scaria, Puthupparampil V.; Anderson, Charles; Narum, David L.; Salanti, Ali; Fried, Michal; Theander, Thor G.; Gamain, Benoit; Duffy, Patrick E. Share Save
Bispecific T cell-engager targeting oncofetal chondroitin sulfate induces complete tumor regression and protective immune memory in mice Skeltved, Nanna; Nordmaj, Mie A. A.; Berendtsen, Nicolai T. T.; Dagil, Robert; Stormer, Emilie M. R.; Al-Nakouzi, Nader; Jiang, Ke; Aicher, Alexandra; Heeschen, Christopher; Gustavsson, Tobias; Choudhary, Swati; Gogenur, Ismail; Christensen, Jan P. P.; Theander, Thor G. G.; Daugaard, Mads; Salanti, Ali; Nielsen, Morten A. A. Share Save
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Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA Raghavan, Sai Sundar Rajan; Dagil, Robert; Lopez-Perez, Mary; Conrad, Julian; Bassi, Maria Rosaria; Quintana, Maria del Pilar; Choudhary, Swati; Gustavsson, Tobias; Wang, Yong; Gourdon, Pontus; Ofori, Michael Fokuo; Christensen, Sebastian Boje; Minja, Daniel Thomas Remias; Schmiegelow, Christentze; Nielsen, Morten Agertoug; Barfod, Lea; Hviid, Lars; Salanti, Ali; Lavstsen, Thomas; Wang, Kaituo Share Save
Two-component vaccine consisting of virus-like particles displaying hepatitis C virus envelope protein 2 oligomers Prentoe, Jannick; Janitzek, Christoph M.; Velazquez-Moctezuma, Rodrigo; Soerensen, Andreas; Jorgensen, Thomas; Clemmensen, Stine; Soroka, Vladislav; Thrane, Susan; Theander, Thor; Nielsen, Morten A.; Salanti, Ali; Bukh, Jens; Sander, Adam F. Share Save
An S1-Nanoparticle Vaccine Protects against SARS-CoV-2 Challenge in K18-hACE2 Mice van Oosten, Linda; Yan, Kexin; Rawle, Daniel J.; Le, Thuy T.; Altenburg, Jort J.; Fougeroux, Cyrielle; Goksoyr, Louise; Adriaan de Jongh, Willem; Nielsen, Morten A.; Sander, Adam F.; Pijlman, Gorben P.; Suhrbier, Andreas Share Save
The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner (vol 9, 3279, 2018) Agerbaek, Mette O.; Bang-Christensen, Sara R.; Yang, Ming-Hsin; Clausen, Thomas M.; Pereira, Marina A.; Sharma, Shreya; Ditlev, Sisse B.; Nielsen, Morten A.; Choudhary, Swati; Gustavsson, Tobias; Sorensen, Poul H.; Meyer, Tim; Propper, David; Shamash, Jonathan; Theander, Thor G.; Aicher, Alexandra; Daugaard, Mads; Heeschen, Christopher; Salanti, Ali Share Save
A Capsid Virus-Like Particle-Based SARS-CoV-2 Vaccine Induces High Levels of Antibodies and Protects Rhesus Macaques Volkmann, Ariane; Koopman, Gerrit; Mooij, Petra; Verschoor, Ernst J.; Verstrepen, Babs E.; Bogers, Willy M. J. M.; Idorn, Manja; Paludan, Soren R.; Vang, Soren; Nielsen, Morten A.; Sander, Adam F.; Schmittwolf, Carolin; Hochrein, Hubertus; Chaplin, Paul Share Save
The C-terminal tail of α-synuclein protects against aggregate replication but is critical for oligomerization Farzadfard, Azad; Pedersen, Jannik Nedergaard; Meisl, Georg; Somavarapu, Arun Kumar; Alam, Parvez; Goksoyr, Louise; Nielsen, Morten Agertoug; Sander, Adam Frederik; Knowles, Tuomas P. J.; Pedersen, Jan Skov; Otzen, Daniel Erik Share Save
Two-Component Nanoparticle Vaccine Displaying Glycosylated Spike S1 Domain Induces Neutralizing Antibody Response against SARS-CoV-2 Variants van Oosten, Linda; Altenburg, Jort J.; Fougeroux, Cyrielle; Geertsema, Corinne; van den End, Fred; Evers, Wendy A. C.; Westphal, Adrie H.; Lindhoud, Simon; van den Berg, Willy; Swarts, Daan C.; Deurhof, Laurens; Suhrbier, Andreas; Le, Thuy T.; Morales, Shessy Torres; Myeni, Sebenzile K.; Kikkert, Marjolein; Sander, Adam F.; Adriaan de Jongh, Willem; Dagil, Robert; Nielsen, Morten A.; Salanti, Ali; Sogaard, Max; Keijzer, Timo M. P.; Weijers, Dolf; Eppink, Michel H. M.; Wijffels, Rene H.; van Oers, Monique M.; Martens, Dirk E.; Pijlman, Gorben P. Share Save
Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination Larsen, Mads Delbo; Lopez-Perez, Mary; Dickson, Emmanuel Kakra; Ampomah, Paulina; Tuikue Ndam, Nicaise; Nouta, Jan; Koeleman, Carolien A. M.; Ederveen, Agnes L. Hipgrave; Mordmueller, Benjamin; Salanti, Ali; Nielsen, Morten Agertoug; Massougbodji, Achille; van der Schoot, C. Ellen; Ofori, Michael F.; Wuhrer, Manfred; Hviid, Lars; Vidarsson, Gestur Share Save
Developing a multivariate prediction model of antibody features associated with protection of malaria-infected pregnant women from placental malaria Aitken, Elizabeth H.; Damelang, Timon; Ortega-Pajares, Amaya; Alemu, Agersew; Hasang, Wina; Dini, Saber; Unger, Holger W.; Ome-Kaius, Maria; Nielsen, Morten A.; Salanti, Ali; Smith, Joe; Kent, Stephen; Hogarth, P. Mark; Wines, Bruce D.; Simpson, Julie A.; Chung, Amy; Rogerson, Stephen J. Share Save
Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding Wang, Kaituo; Dagil, Robert; Lavstsen, Thomas; Misra, Sandeep K.; Spliid, Charlotte B.; Wang, Yong; Gustavsson, Tobias; Sandoval, Daniel R.; Vidal-Calvo, Elena Ethel; Choudhary, Swati; Agerbaek, Mette O.; Lindorff-Larsen, Kresten; Nielsen, Morten A.; Theander, Thor G.; Sharp, Joshua S.; Clausen, Thomas Mandel; Gourdon, Pontus; Salanti, Ali Share Save
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