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Preclinical efficacy of combinatorial B7-H3 CAR T cells and ONC206 against diffuse intrinsic pontine glioma Timpanaro, Andrea; Song, Edward Z.; Toumi, Ryma; Elena-Sanchez, Leonel; Piccand, Caroline; Nemec, Kelsey M.; Kordowski, Anja; Lau, Davina; Johnson, Scott; Winter, Lily; Rajendran, Ashmitha; Ronsley, Rebecca; Oda, Shannon K.; Gustafson, Joshua A.; Wendler, Jason P.; Koschmann, Carl; Evans, Myron; Pattwell, Siobhan; Jensen, Michael C.; Foster, Jessica B.; Dun, Matthew D.; Meechan, Michael; Biery, Matthew C.; Vitanza, Nicholas A. Share Save
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PROTEIN CHANGES IN SERIAL CSF SAMPLES REFLECT CAR ACTIVITY, TOXICITY AND DISEASE RESPONSE IN PATIENTS WITH DIPG TREATED ON THE BRAINCHILD03 TRIAL Ronsley, Rebecca; Chowdhury, Shrabanti; Abdollahi, Kourosh; Ivey, Richard; Whitaker, Jeffrey; Wendler, Jason; Jensen, Michael; Wang, Pei; Vitanza, Nicholas; Paulovich, Amanda Share Save
Leveraging the immunomodulatory effects of dordaviprone (ONC201) to induce long-term survival response in diffuse midline glioma patients and models Savary, Clara; Persson, Mika L.; Jackson, Evangeline R.; Duchatel, Ryan J.; Vo, Tuan; Findlay, Izac J.; Douglas, Alicia M.; Bramberger, Liesl; De La Nava, Daniel; Thomas, Bryce C.; Mcewen, Holly P.; Beitaki, Tyrone S.; De La Fuente, Laura Rodriguez; Colino-Sanguino, Yolanda; Mora, Fatima Valdes; Larsen, Martin R.; Faridi, Pouya; Holst, Jeff; Mayall, Jemma; Kline, Cassie N.; Franson, Andrea T.; Venneti, Sriram; Hondermarck, Hubert; Horvat, Jay; Nixon, Brett; Cartaxo, Rodrigo; Nazarian, Javad; Hulleman, Esther; Mueller, Sabine; Vitanza, Nicholas A.; Koschmann, Carl; Alonso, Marta M.; Carvalheiro, Tiago Ferreira; Van Der Lugt, Jasper; Dun, Matthew D. Share Save
ENHANCING GENOME ANALYSIS WITH WHOLE PROTEOME PROFILING FOR IMPROVED THERAPEUTIC DECISION MAKING IN DIFFUSE MIDLINE GLIOMA Findlay, Izac; Staudt, Dilana; Duchatel, Ryan; Jackson, Evangeline; Persson, Mika; McEwen, Holly; Delevaux, Katherine; Smith, Nathan; Vitanza, Nicholas; Cain, Jason; Hansen, Mitchell; Alvaro, Frank; Jakobsen, Lene; Larsen, Martin; Savary, Clara; Waszak, Sebastian; Dun, Matthew Share Save
PIONEERING QUAD-TARGETING CAR T CELL THERAPY IN PEDIATRIC CNS TUMORS - ANALYSIS FROM THE FIRST-IN-HUMAN PHASE 1 TRIAL BRAINCHILD-04 Ronsley, Rebecca; Seidel, Kristy; Narayanaswamy, Prabha; Pattabhi, Sowmya; Wendler, Jason; Rawlings-Rhea, Stephanie; Huang, Wenjun; Crotty, Erin; Leary, Sarah; Lee, Amy; Park, Julie; Jensen, Michael; Vitanza, Nicholas Share Save
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Tumor inflammation-associated neurotoxicity in children with diffuse intrinsic pontine glioma receiving B7-H3-targeting CAR T cells on BrainChild-03 Ronsley, Rebecca; Choe, Michelle; Wright, Jason; Seidel, Kristy; Lee, Amy; Wendler, Jason; Annesley, Colleen; Jensen, Michael C.; Park, Julie R.; Vitanza, Nicholas A.; Gust, Juliane Share Save
Locoregional infusion of EGFR806-CAR T cells for recurrent or refractory pediatric CNS tumors: Results of the completed BrainChild02 phase 1 clinical trial Gust, Juliane; Cole, Bonnie L.; Ronsley, Rebecca; Wilson, Ashley L.; Seidel, Kristy; Wendler, Jason; Pattabhi, Sowmya; Brown, Christopher; Rawlings-Rhea, Stephanie D.; Shtanukhina, Nadezhda; Browd, Samuel R.; Hauptman, Jason S.; Lee, Amy; Ojemann, Jeffrey G.; Crotty, Erin E.; Leary, Sarah E. S.; Perez, Francisco A.; Wright, Jason N.; Albert, Catherine M.; Pinto, Navin; Gardner, Rebecca A.; Vitanza, Nicholas A.; Jensen, Michael C.; Park, Julie R. Share Save
PIONEERING QUAD-TARGETING CAR T CELL THERAPY IN PEDIATRIC CNS TUMORS - ANALYSIS FROM THE INITIAL PATIENTS TREATED ON THE FIRST-IN-HUMAN PHASE 1 TRIAL BRAINCHILD-04 Ronsley, Rebecca; Seidel, Kristy; Narayanaswamy, Prabha; Pattabhi, Sowmya; Wendler, Jason; Ho, On; Rawlings-Rhea, Stephanie; Gust, Juliane; Huang, Wenjun; Crotty, Erin; Leary, Sarah; Runco, Daniel; Hauptman, Jason; Gardner, Rebecca; Park, Julie; Annesley, Colleen; Jensen, Michael; Vitanza, Nicholas Share Save
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An international study presenting a federated learning AI platform for pediatric brain tumors Lee, Edward H.; Han, Michelle; Wright, Jason; Kuwabara, Michael; Mevorach, Jacob; Fu, Gang; Choudhury, Olivia; Ratan, Ujjwal; Zhang, Michael; Wagner, Matthias W.; Goetti, Robert; Toescu, Sebastian; Perreault, Sebastien; Dogan, Hakan; Altinmakas, Emre; Mohammadzadeh, Maryam; Szymanski, Kathryn A.; Campen, Cynthia J.; Lai, Hollie; Eghbal, Azam; Radmanesh, Alireza; Mankad, Kshitij; Aquilina, Kristian; Said, Mourad; Vossough, Arastoo; Oztekin, Ozgur; Ertl-Wagner, Birgit; Poussaint, Tina; Thompson, Eric M.; Ho, Chang Y.; Jaju, Alok; Curran, John; Ramaswamy, Vijay; Cheshier, Samuel H.; Grant, Gerald A.; Wong, S. Simon; Moseley, Michael E.; Lober, Robert M.; Wilms, Mattias; Forkert, Nils D.; Vitanza, Nicholas A.; Miller, Jeffrey H.; Prolo, Laura M.; Yeom, Kristen W. Share Save
Cerebrospinal fluid liquid biopsy by low-pass whole genome sequencing for clinical disease monitoring in pediatric embryonal tumors Crotty, Erin E.; Paulson, Vera A.; Ronsley, Rebecca; Vitanza, Nicholas A.; Lee, Amy; Hauptman, Jason; Goldstein, Hannah E.; Lockwood, Christina M.; Leary, Sarah E. S.; Cole, Bonnie L. Share Save
INTRAVENTRICULAR B7-H3 CAR T CELLS FOR DIFFUSE INTRINSIC PONTINE GLIOMA: SAFETY AND EFFICACY REPORT FROM THE COMPLETED PHASE 1 TRIAL BRAINCHILD-03 Vitanza, Nicholas A.; Ronsley, Rebecca; Huang, Wenjuan; Seidel, Kristy; Thomsen, Alison; Gust, Juliane; Hauptman, Jason; Choe, Michlle; Crotty, Erin; Leary, Sarah; Gustafson, Joshua A.; Gardner, Rebecca A.; Pattabhi, Sowmya; Wendler, Jason; Ho, On; Annesley, Colleen; Park, Julie R.; Jensen, Michael C. Share Save
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DRD2 ANTAGONISM RESCUES IMMUNE-TUMOR SURVEILLANCE, WARMING THE TUMOR IMMUNE MICROENVIRONMENT OF DIFFUSE MIDLINE GLIOMA MODELS Persson, Mika L.; Jackson, Evangeline R.; Duchatel, Ryan J.; de la Nava, Daniel; Thomas, Bryce C.; Savary, Clara; Mcewen, Holly P.; Beitaki, Tyrone S.; Kearney, Padraic S.; Findlay, Izac J.; Douglas, Alicia M.; Larsen, Martin R.; Faridi, Pouya; Holst, Jeff; Mayall, Jemma; Hondermarck, Hubert; Horvat, Jay; Nixon, Brett; Cartaxo, Rodrigo T.; Nazarian, Javad; Hulleman, Esther; Mueller, Sabine; Vitanza, Nicholas A.; Koshmann, Carl; Alonso, Marta M.; Carvalheiro, Tiago; van der Lugt, Jasper; Dun, Matthew D. Share Save
CSF LIQUID BIOPSY: PAVING THE WAY FOR MINIMALLY INVASIVE BRAIN TUMOR SURVEILLANCE USING LOW-PASS WHOLE GENOME SEQUENCING Tam, Lydia T.; Rossi, Grace; Stevens, Jeff; Ronsley, Rebecca; Vitanza, Nicholas A.; Cole, Bonnie L.; Paulson, Vera A.; Lockwood, Christina M.; Leary, Sarah E. S.; Crotty, Erin E. Share Save
TUMOR INFLAMMATION-ASSOCIATED NEUROTOXICITY (TIAN): A TOXICITY SYNDROME IN PATIENTS TREATED WITH IMMUNOTHERAPY FOR CENTRAL NERVOUS SYSTEM TUMORS Mahdi, Jasia; Dietrich, Jorg; Straathof, Karin; Roddie, Claire; Scott, Brian J.; Davidson, Tom Belle; Prolo, Laura; Batchelor, Tracy T.; Campen, Cynthia J.; Davis, Kara L.; Gust, Juliane; Lim, Michael; Majzner, Robbie G.; Park, Julie R.; Partap, Sonia; Ramakrishna, Sneha; Richards, Rebecca; Schultz, Liora; Vitanza, Nicholas A.; Wang, Leo D.; Mackall, Crystal L.; Monje, Michelle Share Save
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