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J

Jan Paulo T. Zaragoza

discovery biologics, merck & co., inc., 213 east grand ave., south san francisco, ca 94080, usa

12H-index
33Paper Count
759Citation Count
Published Papers 14
Publication Date
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Structural Characterization of Linker Shielding in ADC Site-Specific Conjugates
errPharmaceutics 2025, Vol. 17, Page 1568
IF5.5
err2025-12-05
err0
errOAAI
errMaru Jaime-Garza; Andrew Waight; Manish Hudlikar; Michael J. Eddins; Elnaz S. Rasti; Jan Paulo T. Zaragoza; Laurence Fayadat-Dilman; Jill E. Chrencik; Sandra B. Gabelli; Yun-Ting Chen; Cameron L. Noland
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Biologics developability data analysis using hierarchical clustering accelerates candidate lead selection, optimization, and preformulation screening
errmAbs
IF7.3
err2025-05-10
err0
errOAAI
errKevin James Metcalf; Galen Wo; Jan Paulo Zaragoza; Fahimeh Raoufi; Jeanne Baker; Daoyang Chen; Mehabaw Derebe; Jason Hogan; Amy Hsu; Esther Kofman; David Leigh; Mandy Li; Dan Malashock; Cate Mann; Soha Motlagh; Jihea Park; Karthik Sathiyamoorthy; Madhura Shidhore; Yinyan Tang; Kevin Teng; Katharine Williams; Andrew Waight; Sultan Yilmaz; Fan Zhang; Huimin Zhong; Laurence Fayadat-Dilman; Marc Bailly
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errSave
Characterizing Monoclonal Antibody Aggregation Using Charge Detection Mass Spectrometry and Industry Standard Methods
errJOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
IF2.7
err2025-03-01
err0
PREAI
errJordan, Jacob S.; Harper, Conner C.; Zhang, Fan; Kofman, Esther; Sam, Miranda; Zaragoza, Jan Paulo; Bhagwat, Bhagyashree; Fayadat-Dilman, Laurence; Williams, Evan R.
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errSave
Charge Detection Mass Spectrometry Reveals Conformational Heterogeneity in Megadalton-Sized Monoclonal Antibody Aggregates
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-08-07
err2
PREAI
errJordan, Jacob S.; Harper, Conner C.; Zhang, Fan; Kofman, Esther; Li, Mandy; Sathiyamoorthy, Karthik; Zaragoza, Jan Paulo; Fayadat-Dilman, Laurence; Williams, Evan R.
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errSave
Temporal and spatial resolution of distal protein motions that activate hydrogen tunneling in soybean lipoxygenase
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2023-03-03
err19
errOAAI
errZaragoza, Jan Paulo T.; Offenbacher, Adam R.; Hu, Shenshen; Gee, Christine L.; Firestein, Zachary M.; Minnetian, Natalie; Deng, Zhenyu; Fan, Flora; Iavarone, Anthony T.; Klinman, Judith P.
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Biochemical and crystallographic investigations into isonitrile formation by a nonheme iron-dependent oxidase/decarboxylase
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2021-01-01
err19
errOAAI
errJonnalagadda, Rohan; Flores, Antonio Del Rio; Cai, Wenlong; Mehmood, Rimsha; Narayanamoorthy, Maanasa; Ren, Chaoxiang; Zaragoza, Jan Paulo T.; Kulik, Heather J.; Zhang, Wenjun; Drennan, Catherine L.
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Hydroxyl Transfer to Carbon Radicals by Mn(OH) vs Fe(OH) Corrole Complexes
errINORGANIC CHEMISTRY
IF4.7
err2020-10-13
err28
errOAAI
errCummins, Daniel C.; Alvarado, Jessica G.; Zaragoza, Jan Paulo T.; Mubarak, Muhammad Qadri Effendy; Lin, Yen-Ting; de Visser, Sam P.; Goldberg, David P.
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Hydrogen Atom Abstraction by High-Valent Fe(OH) versus Mn(OH) Porphyrinoid Complexes: Mechanistic Insights from Experimental and Computational Studies
errINORGANIC CHEMISTRY
IF4.7
err2019-12-05
err30
errOAAI
errZaragoza, Jan Paulo T.; Cummins, Daniel C.; Mubarak, M. Qadri E.; Siegler, Maxime A.; de Visser, Sam P.; Goldberg, David P.
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errSave
A Reactive Manganese(IV)-Hydroxide Complex: A Missing Intermediate in Hydrogen Atom Transfer by High-Valent Metal-Oxo Porphyrinoid Compounds
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2018-03-15
err52
errOAAI
errZaragoza, Jan Paulo T.; Siegler, Maxime A.; Goldberg, David P.
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Direct Observation of Oxygen Rebound with an Iron-Hydroxide Complex
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2017-09-20
err85
errOAAI
errZaragoza, Jan Paulo T.; Yosca, Timothy H.; Siegler, Maxime A.; Moenne-Loccoz, Pierre; Green, Michael T.; Goldberg, David P.
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meso-N-Methylation of a porphyrinoid complex: activating the H-atom transfer capability of an inert ReV(O) corrolazine
errCHEMICAL COMMUNICATIONS
IF4.2
err2017-01-01
err3
errOAAI
errJoslin, Evan E.; Zaragoza, Jan Paulo T.; Siegler, Maxime A.; Goldberg, David P.
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errSave
The Influence of Peripheral Substituent Modification on PV, MnIII, and MnV(O) Corrolazines: X-ray Crystallography, Electrochemical and Spectroscopic Properties, and HAT and OAT Reactivities
errINORGANIC CHEMISTRY
IF4.7
err2016-08-16
err22
errOAAI
errJoslin, Evan E.; Zaragoza, Jan Paulo T.; Baglia, Regina A.; Siegler, Maxime A.; Goldberg, David P.
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Rhenium(v)-oxo corrolazines: isolating redox-active ligand reactivity
errCHEMICAL COMMUNICATIONS
IF4.2
err2016-01-01
err18
errOAAI
errZaragoza, Jan Paulo T.; Siegler, Maxime A.; Goldberg, David P.
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errSave
Strong Inhibition of O-Atom Transfer Reactivity for MnIV(O)(π-Radical-Cation)(Lewis Acid) versus MnV(O) Porphyrinoid Complexes
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2015-05-12
err56
errOAAI
errZaragoza, Jan Paulo T.; Baglia, Regina A.; Siegler, Maxime A.; Goldberg, David P.
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
D
David A. Leigh
H-index: 106 · Papers: 700
J
Judith P. Klinman
H-index: 81 · Papers: 462
S
Sam P. de Visser
H-index: 81 · Papers: 419
E
Evan R. Williams
H-index: 80 · Papers: 344
C
Catherine L. Drennan
H-index: 63 · Papers: 480
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