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In vivo CRISPR/Cas9 screens identify new regulators of B cell activation and plasma cell differentiation Calderon, Lesly; Schaefer, Markus; Roncevic, Marina; Rauschmeier, Rene; Jaritz, Markus; Schwickert, Tanja A.; Sun, Qiong; Pauli, Andrea; Zuber, Johannes; Busslinger, Meinrad Share Save
Loss-of-function genetic screen unveils synergistic efficacy of PARG inhibition with combined 5-fluorouracil and irinotecan treatment in colorectal cancer Queralt, Cristina; Moreta-Moraleda, Cristina; Costa, Marta; Grau-Leal, Ferran; Diesch, Jeannine; Vendrell-Ayats, Carla; Musulen, Eva; Wright, Roni H. G.; Buges, Cristina; Manzano, Jose Luis; Cabrero-De Las Heras, Sara; Zuber, Johannes; Buschbeck, Marcus; Forcales, Sonia-v; Martinez-Balibrea, Eva Share Save
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ERH regulates type II interferon immune signaling through post-transcriptional regulation of JAK2 mRNA Soderholm, Adrian; Vunjak, Milica; de Almeida, Melanie; Popitsch, Niko; Podvalnaya, Nadezda; Araguas-Rodriguez, Pablo; Scinicariello, Sara; Nischwitz, Emily; Butter, Falk; Ketting, Rene F.; Ameres, Stefan L.; Mueller-McNicoll, Michaela; Zuber, Johannes; Versteeg, Gijs A. Share Save
mTORC1 cooperates with tRNA wobble modification to sustain the protein synthesis machinery Hermann, Julia; Bortecen, Toman; Kalis, Robert; Kowar, Alexander; Pechincha, Catarina; Vogt, Vivien; Schneider, Martin; Helm, Dominic; Krijgsveld, Jeroen; Loayza-Puch, Fabricio; Zuber, Johannes; Palm, Wilhelm Share Save
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Murine neonatal cardiac regeneration depends on Insulin-like growth factor 1 receptor signaling Schuetz, Thomas; Dolejsi, Theresa; Beck, Eva; Fugger, Fabio; Bild, Alexander; Duin, Marie-Theres; Gavranovic-Novakovic, Jasmina; Hilbold, Erika; Hoffmann, Thomas; Zuber, Johannes; Bauer, Axel; Ruschitzka, Frank; Bar, Christian; Penninger, Josef Martin; Haubner, Bernhard Johannes Share Save
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation Kagiou, Chrysanthi; Cisneros, Jose A.; Farnung, Jakob; Liwocha, Joanna; Offensperger, Fabian; Dong, Kevin; Yang, Ka; Tin, Gary; Horstmann, Christina S.; Hinterndorfer, Matthias; Paulo, Joao A.; Scholes, Natalie S.; Sanchez Avila, Juan; Fellner, Michaela; Andersch, Florian; Hannich, J. Thomas; Zuber, Johannes; Kubicek, Stefan; Gygi, Steven P.; Schulman, Brenda A.; Winter, Georg E. Share Save
QUANTROseq, a transcriptomic based drug discovery platform using time-resolved gene expression profiling: Identification of inhibitors and degraders of transcription factors and cell signaling regulators Sabo, Arianna; Griesmayr, Nina Fasching; Neumann, Tobias; Manzenreither, Raphael; Ivankovic, Maja; Costa, Rodrigo Pacheco Valamatos; Rieser, Sarah; Scinicariello, Sara; Triska, Petr; Stingeder, Anna; Gruss, Astrid; Cubero, Ryan; Frank, Olga; Sowemimo, Ivica; Kirchgatterer, Paul; Cantoran, Adriana; Ameres, Stefan; Zuber, Johannes; Bauer, Michael Share Save
Cancer Evolution: A Multifaceted Affair Ciriello, Giovanni; Magnani, Luca; Aitken, Sarah J.; Akkari, Leila; Behjati, Sam; Hanahan, Douglas; Landau, Dan A.; Lopez-Bigas, Nuria; Lupianez, Dario G.; Marine, Jean-Christophe; Martin-Villalba, Ana; Natoli, Gioacchino; Obenauf, Anna C.; Oricchio, Elisa; Scaffidi, Paola; Sottoriva, Andrea; Swarbrick, Alexander; Tonon, Giovanni; Vanharanta, Sakari; Zuber, Johannes Share Save
The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG Kugler, Eitan; Madiwale, Shreyas; Yong, Darren; Thoms, Julie A. I.; Birger, Yehudit; Sykes, David B.; Schmoellerl, Johannes; Drakul, Aneta; Priebe, Valdemar; Yassin, Muhammad; Aqaqe, Nasma; Rein, Avigail; Fishman, Hila; Geron, Ifat; Chen, Chun-Wei; Raught, Brian; Liu, Qiao; Ogana, Heather; Liedke, Elisabeth; Bourquin, Jean-Pierre; Zuber, Johannes; Milyavsky, Michael; Pimanda, John; Prive, Gilbert G.; Izraeli, Shai Share Save
ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia Ebner, Jessica; Schmoellerl, Johannes; Piontek, Martin; Manhart, Gabriele; Troester, Selina; Carter, Bing Z.; Neubauer, Heidi; Moriggl, Richard; Szakacs, Gergely; Zuber, Johannes; Koecher, Thomas; Andreeff, Michael; Sperr, Wolfgang R.; Valent, Peter; Grebien, Florian Share Save
CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax Neault, Mathieu; Lebert-Ghali, Charles-Etienne; Fournier, Marilaine; Capdevielle, Caroline; Garfinkle, Elizabeth A. R.; Obermayer, Alyssa; Cotton, Anitria; Boulay, Karine; Sawchyn, Christina; St-Amand, Sarah; Nguyen, Kamy H.; Assaf, Beatrice; Mercier, Francois E.; Delisle, Jean-Sebastien; Drobetsky, Elliot A.; Hulea, Laura; Shaw, Timothy I.; Zuber, Johannes; Gruber, Tanja A.; Melichar, Heather J.; Mallette, Frederick A. Share Save
SPOP targets the immune transcription factor IRF1 for proteasomal degradation Schwartz, Irene; Vunjak, Milica; Budroni, Valentina; Garcia, Adriana Cantoran; Mastrovito, Marialaura; Soderholm, Adrian; Hinterndorfer, Matthias; de Almeida, Melanie; Hacker, Kathrin; Wang, Jingkui; Froussios, Kimon; Jude, Julian; Decker, Thomas; Zuber, Johannes; Versteeg, Gijs A. Share Save
MYC determines lineage commitment in KRAS-driven primary liver cancer development D'Artista, Luana; Moschopoulou, Athina Anastasia; Barozzi, Iros; Craig, Amanda J.; Seehawer, Marco; Herrmann, Lea; Minnich, Martina; Kang, Tae-Won; Rist, Elke; Henning, Melanie; Klotz, Sabrina; Heinzmann, Florian; Harbig, Jule; Sipos, Bence; Longerich, Thomas; Eilers, Martin; Dauch, Daniel; Zuber, Johannes; Wang, Xin Wei; Zender, Lars Share Save
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