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Nicole Kleinstreuer

national institutes of health

53H-index
286Paper Count
1.4WCitation Count
Published Papers 134
Publication Date
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Nourishing collaboration: interdisciplinary nutrition education for health care professionals
errAmerican Journal of Clinical Nutrition
IF6.9
err2026-07-04
err0
PREAI
errAndrew A Bremer; Holly L Nicastro; Emily Levin; Nicole Kleinstreuer
errShare
errSave
Validation of the Electrophilic Allergen Screening Assay for Detection of Key Event 1 of the Skin Sensitization Adverse Outcome Pathway
errToxics
IF4.1
err2026-06-12
err0
errOAAI
errEmily N. Reinke; Elijah J. Petersen; John D. Gordon; Rick Uhl; Valerie H. Adams; Diego Rua; Victor J. Johnson; Gary R. Burleson; Judy Strickland; Robert Gutierrez; Catherine S. Sprankle; Tripp LaPratt; David M. Lehmann; Dori R. Germolec; Nicole C. Kleinstreuer
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errSave
Democratizing Artificial Intelligence in Toxicology: Real-World Applications and Automated Computational Workflows
errChemical Research in Toxicology
IF3.8
err2026-05-29
err0
errOAAI
errKamel Mansouri; José Teófilo Moreira-Filho; Ricardo S Tieghi; Nicole Kleinstreuer
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errSave
Reimagining human-centric drug development with new approach methodologies
errScience
IF45.8
err2026-04-16
err0
PREAI
errXuekun Wu; Matthew A. Wu; James Zou; Nicole Kleinstreuer; Joseph C. Wu
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errSave
Interlaboratory validation of the human thyroid microtissue assay
errTOXICOLOGICAL SCIENCES
IF4.1
err2025-12-01
err0
PREAI
errDeisenroth, Chad; Foley, Briana; Rogers, Eda; Kuhnlenz, Julia; Chen, Wei; Feshuk, Madison; Bianchi, Enrica; Mckenna, Josiah; Hill, Bridgett N.; Larocca, Jessica; LeCluyse, Edward L.; Kleinstreuer, Nicole; Thomas, Russell S.; Hogberg, Helena T.
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errSave
Industrial and agricultural chemicals exhibit antimicrobial activity against human gut bacteria in vitro
errNature Microbiology
IF19.4
err2025-11-26
err0
errOAAI
errIndra Roux; Anna E. Lindell; Anne Grießhammer; Tom Smith; Shagun Krishna; Rui Guan; Deniz Rad; Luisa Faria; Sonja Blasche; Kaustubh R. Patil; Nicole C. Kleinstreuer; Lisa Maier; Stephan Kamrad; Kiran R. Patil
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errSave
Machine Learning Modeling for ABC Transporter Efflux and Inhibition: Data Curation; Model Development; and New Compound Interaction Predictions
errMolecular Pharmaceutics
IF4.5
err2025-10-20
err0
errOAAI
errNada J. Daood; Sean R. Carey; Elena Chung; Tong Wang; Anna Kreutz; Mounika Girireddy; Suman Chakravarti; Nicole C. Kleinstreuer; Jacqueline B. Tiley; Lauren M. Aleksunes; Hao Zhu
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errSave
The OASIS Consortium: integrating multi-omics technologies to transform chemical safety assessment
errTOXICOLOGICAL SCIENCES
IF4.1
err2025-10-01
err0
errOAAI
errRouquie, David; Bender, Andreas; Cheah, Jaime; Crute, Christine E.; Dalmas, Deidre; Ewald, Jessica; Fullerton, Aaron; Harrill, Joshua A.; Kadri, Sabah; Kleinstreuer, Nicole; Kramer, Nynke; LaRocca, Jessica; Mitchell, Constance A.; Seal, Srijit; Singh, Shantanu; Carpenter, Anne E.
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Human organoids for Risk Group 4 virus research: a new frontier in investigating Nipah virus infection of the central nervous system
errJOURNAL OF VIROLOGY
IF3.8
err2025-10-01
err0
PREAI
errWorwa, Gabriella; Yu, Shuqing; Hischak, Amanda M. W.; Tran, Julie P.; Bearss, Jeremy J.; Bernbaum, John; Woodburn, Daniel B.; Pahar, Bapi; Geiger, Jillian; Huzella, Louis M.; Freire, Santiago Vidal; Crozier, Ian; Munoz-Fontela, Cesar; Palacios, Gustavo; Kleinstreuer, Nicole C.; Widerspick, Lina; Kuhn, Jens H.
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errSave
Automating Data Extraction From Scientific Literature and General PDF Files Using Large Language Models and KNIME: An Application in Toxicology
errWILEY INTERDISCIPLINARY REVIEWS-COMPUTATIONAL MOLECULAR SCIENCE
IF27
err2025-09-18
err0
PREAI
errMoreira-Filho, Jose Teofilo; Ranganath, Dhruv; Tieghi, Ricardo S.; Patton, Robert; Sutherland, Vicki; Schmitt, Charles; Rooney, Andrew A.; Fostel, Jennifer; Walker, Vickie R.; Saddler, Trey; Reif, David; Mansouri, Kamel; Kleinstreuer, Nicole
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errSave
High-Throughput Cytokine Detection Platform for Evaluation of Chemical Induced Microglial Activation
errSLAS Technology
IF3.7
err2025-09-10
err0
errOAAI
errShu Yang; Kelly E. Carstens; Ibukunoluwa Ipaye; Xing Chen; Helena T. Hogberg; Nicole Kleinstreuer; Thomas B. Knudsen; Menghang Xia
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errSave
BioBricks.ai: a versioned data registry for life sciences data assets
errFrontiers in Artificial Intelligence
IF4.7
err2025-08-13
err0
errOAAI
errYifan Gao; Zakariyya Mughal; Jose A. Jaramillo-Villegas; Marie Corradi; Alexandre Borrel†; Ben Lieberman; Suliman Sharif; John Shaffer; Karamarie Fecho; Ajay Chatrath; Alexandra Maertens; Marc A. T. Teunis; Nicole Kleinstreuer; Thomas Hartung; Thomas Luechtefeld
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errSave
Synergistic toxicity in alcohol-associated liver disease and PFAS exposure
errTOXICOLOGICAL SCIENCES
IF4.1
err2025-08-01
err1
PREAI
errStem, Arthur D.; Tieghi, Ricardo Scheufen; Chatzi, Vaia Lida; Kleinstreuer, Nicole; Valvi, Damaskini; Thompson, David C.; Vasiliou, Vasilis
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The Long Way from Raw Data to NAM-Based Information: Overview on Data Layers and Processing Steps
errALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION
IF5.8
err2025-01-01
err3
errOAAI
errBlum, J; Brüll, M; Hengstler, JG; Dietrich, DR; Gruber, AJ; Dipalo, M; Kraushaar, U; Mangas, I; Terron, A; Fritsche, E; Marx-Stoelting, P; Hardy, B; Schepky, A; Escher, SE; Hartung, T; Landsiedel, R; Odermatt, A; Sachana, M; Koch, K; Dönmez, A; Masjosthusmann, S; Bothe, K; Schildknecht, S; Beilmann, M; Beltman, JB; Fitzpatrick, S; Mangerich, A; Rehm, M; Tangianu, S; Zickgraf, FM; Kamp, H; Burger, G; van de Water, B; Kleinstreuer, N; White, A; Leist, M
errShare
errSave
Challenges and Opportunities for Validation of AI-Based New Approach Methods
errALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION
IF5.8
err2025-01-01
err5
errOAAI
errHartung, T; Kleinstreuer, N
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errSave
A Novel Machine Learning Model and a Web Portal for Predicting the Human Skin Sensitization Effects of Chemical Agents
errTOXICS
IF4.1
err2024-11-07
err0
errOAAI
errTieghi, Ricardo Scheufen; Moreira-Filho, Jose Teofilo; Martin, Holli-Joi; Wellnitz, James; Otoch, Miguel Canamary; Rath, Marielle; Tropsha, Alexander; Muratov, Eugene N.; Kleinstreuer, Nicole
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errSave
Democratizing cheminformatics: interpretable chemical grouping using an automated KNIME workflow
errJOURNAL OF CHEMINFORMATICS
IF5.7
err2024-08-16
err3
errOAAI
errMoreira-Filho, Jose T.; Ranganath, Dhruv; Conway, Mike; Schmitt, Charles; Kleinstreuer, Nicole; Mansouri, Kamel
errShare
errSave
Integrated Approach for Testing and Assessment for Developmental Neurotoxicity (DNT) to Prioritize Aromatic Organophosphorus Flame Retardants
errTOXICS
IF4.1
err2024-06-18
err0
errOAAI
errKreutz, Anna; Oyetade, Oluwakemi B.; Chang, Xiaoqing; Hsieh, Jui-Hua; Behl, Mamta; Allen, David G.; Kleinstreuer, Nicole C.; Hogberg, Helena T.
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errSave
Development and validation of CYP26A1 inhibition assay for high-throughput screening
errBIOTECHNOLOGY JOURNAL
IF3.1
err2024-06-11
err0
errOAAI
errSakamuru, Srilatha; Ma, Dongping; Pierro, Jocylin D.; Baker, Nancy C.; Kleinstreuer, Nicole; Cali, James J.; Knudsen, Thomas B.; Xia, Menghang
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Differences in the anatomy and physiology of the human and rat respiratory tracts and impact on toxicological assessments
errREGULATORY TOXICOLOGY AND PHARMACOLOGY
IF3.5
err2024-06-01
err7
errOAAI
errStucki, Andreas O.; Sauer, Ursula G.; Allen, David G.; Kleinstreuer, Nicole C.; Perron, Monique M.; Yozzo, Krystle L.; Lowit, Anna B.; Clippinger, Amy J.
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Research Directions

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Co-authors
Cooperation Journals
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Donald E. Ingber
H-index: 178 · Papers: 719
C
Claudio Franceschi
H-index: 136 · Papers: 1.2K
E
Eric Verdin
H-index: 131 · Papers: 459
C
Cornelia M. Weyand
H-index: 130 · Papers: 573
J
Judith Campisi
H-index: 129 · Papers: 519
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