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J

Jack W. Szostak

The University of Chicago

112H-index
573Paper Count
5.9WCitation Count
Published Papers 182
Publication Date
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A ribozyme ligase that requires a 3′ terminal phosphate on its RNA substrate
errNature Communications
IF15.7
err2026-07-13
err0
errOAAI
errAnnyesha Biswas; Zoe Weiss; Jack W. Szostak; Saurja DasGupta
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Influence of Phosphate Activation Chemistry on the Selection of the Primordial Genetic Alphabet
errJournal of the American Chemical Society
IF15.6
err2026-03-29
err0
errOAAI
errFilip Bošković; Jian Zhang; Alok Apan Swatiputra; Jack W. Szostak
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errSave
Evolution of error correction through a need for speed
errScience
IF45.8
err2026-02-19
err0
PREAI
errRiccardo Ravasio; Kabir Husain; Constantine G. Evans; Rob Phillips; Marco Ribezzi-Crivellari; Jack W. Szostak; Arvind Murugan
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errSave
Impact of 2′-deoxyribo-purine substrates on nonenzymatic RNA template-directed primer extension
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-11-26
err0
PREAI
errFang, Ziyuan; Acikgoz, Orhan; Jia, Xiwen; Essex, Jahmyl; Wen, Ruby; Szostak, Jack W.
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errSave
Efficient Assembly of Functional RNA by in Situ Phosphate Activation and Loop-Closing Ligation
errJournal of the American Chemical Society
IF15.6
err2025-10-20
err0
errOAAI
errJian Zhang; Aleksandar Radakovic; Filip Bošković; Harry R. M. Aitken; Long-Fei Wu; Jack W. Szostak
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errSave
Potentially Prebiotic Isocyanide Activation Chemistry Drives RNA Assembly
errChem. Commun.
IF4.2
err2025-08-06
err0
errOAAI
errStephanie J Zhang; Xiwen Jia; Saurja DasGupta; Jack W Szostak
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Autocatalytic assembly of a chimeric aminoacyl-RNA synthetase ribozyme
errSCIENCE ADVANCES
IF12.5
err2025-04-04
err0
PREAI
errRadakovic, Aleksandar; Todisco, Marco; Mishra, Anmol; Szostak, Jack W.
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Simple Lipids Form Stable Higher-Order Structures in Concentrated Sulfuric Acid
errASTROBIOLOGY
IF2.6
err2025-03-01
err0
PREAI
errDuzdevich, Daniel; Nisler, Collin; Petkowski, Janusz J.; Bains, William; Kaminsky, Caroline K.; Szostak, Jack W.; Seager, Sara
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errSave
Selective Nonenzymatic Formation of Biologically Common RNA Hairpins
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2024-11-26
err0
PREAI
errWu, Long-Fei; Zhang, Junting; Cornwell-Arquitt, Robert; Hendrix, David A.; Radakovic, Aleksandar; Szostak, Jack W.
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errSave
Overcoming nucleotide bias in the nonenzymatic copying of RNA templates
errNUCLEIC ACIDS RESEARCH
IF13.1
err2024-11-12
err0
errOAAI
errDuzdevich, Daniel; Carr, Christopher E.; Colville, Ben W. F.; Aitken, Harry R. M.; Szostak, Jack W.
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errSave
Evolution of the substrate specificity of an RNA ligase ribozyme from phosphorimidazole to triphosphate activation
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-09-13
err0
errOAAI
errDasgupta, Saurja; Weiss, Zoe; Nisler, Collin; Szostak, Jack W.
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errSave
A potential role for RNA aminoacylation prior to its role in peptide synthesis
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-08-23
err0
errOAAI
errRadakovic, Aleksandar; Lewicka, Anna; Todisco, Marco; Aitken, Harry R. M.; Weiss, Zoe; Kim, Shannon; Bannan, Abdullah; Piccirilli, Joseph A.; Szostak, Jack W.
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errSave
Did the exposure of coacervate droplets to rain make them the first stable protocells?
errSCIENCE ADVANCES
IF12.5
err2024-08-23
err2
errOAAI
errAgrawal, Aman; Radakovic, Aleksandar; Vonteddu, Anusha; Rizvi, Syed; Huynh, Vivian N.; Douglas, Jack F.; Tirrell, Matthew V.; Karim, Alamgir; Szostak, Jack W.
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errSave
RNA Complexes with Nicks and Gaps: Thermodynamic and Kinetic Effects of Coaxial Stacking and Dangling Ends
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-06-21
err1
errOAAI
errTodisco, Marco; Radakovic, Aleksandar; Szostak, Jack W.
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errSave
Simulations predict preferred Mg2D coordination in a nonenzymatic primer-extension reaction center
errBIOPHYSICAL JOURNAL
IF3.1
err2024-06-01
err0
errOAAI
errMittal, Shriyaa; Nisler, Collin; Szostak, Jack W.
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errSave
Diaminopurine in Nonenzymatic RNA Template Copying
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-05-31
err1
errOAAI
errJia, Xiwen; Fang, Ziyuan; Kim, Seohyun Chris; Ding, Dian; Zhou, Lijun; Szostak, Jack W.
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errSave
Constraints on the emergence of RNA through non-templated primer extension with mixtures of potentially prebiotic nucleotides
errNUCLEIC ACIDS RESEARCH
IF13.1
err2024-05-10
err1
errOAAI
errJia, Xiwen; Zhang, Stephanie J.; Zhou, Lijun; Szostak, Jack W.
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errSave
Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-04-05
err1
errOAAI
errFang, Ziyuan; Pazienza, Lydia T.; Zhang, Jian; Tam, Chun Pong; Szostak, Jack W.
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errSave
Natural soda lakes provide compatible conditions for RNA and membrane function that could have enabled the origin of life
errPNAS NEXUS
IF3.8
err2024-03-19
err2
errOAAI
errCohen, Zachary R.; Ding, Dian; Zhou, Lijun; Dasgupta, Saurja; Haas, Sebastian; Sinclair, Kimberly P.; Todd, Zoe R.; Black, Roy A.; Szostak, Jack W.; Catling, David C.
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errSave
Transient states during the annealing of mismatched and bulged oligonucleotides
errNUCLEIC ACIDS RESEARCH
IF13.1
err2024-02-13
err3
errOAAI
errTodisco, Marco; Ding, Dian; Szostak, Jack W.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
M
Martin A. Nowak
H-index: 160 · Papers: 700
D
David P. Bartel
H-index: 121 · Papers: 314
E
Elizabeth H. Blackburn
H-index: 113 · Papers: 433
R
Robert E. Kingston
H-index: 104 · Papers: 333
L
L. Mahadevan
H-index: 103 · Papers: 715
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