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The prevalence of ENPP1 deficiency in humans with Ossification of the Posterior Longitudinal Ligament and the preclinical efficacy of ENPP1 enzyme therapy in murine Ossification of the Posterior Longitudinal Ligament Srivastava, Shivani; Kato, Hajime; Von Kroge, Simon; Weise, Keith; Stabach, Paul; Lopez, Sam G.; O'brien, Kevin; Lester, Ethan R.; Kim, Hana; Ishaq, Tayyaba; Dammen-Brower, Kris; Schinke, Thorsten; Kimura, Soichiro; Miyahara, Junya; Doi, Toru; Oshima, Yasushi; Yarema, Kevin J.; Carpenter, Thomas O.; Sabbagh, Yves; Tommasini, Steven M.; Ito, Nobuaki; Oheim, Ralf; Braddock, Demetrios T. Share Save
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Allografts promote skeletal regeneration of periprosthetic femoral bone loss von Kroge, Simon; Schmidt, Constantin; Butscheidt, Sebastian; Ohlmeier, Malte; Amling, Michael; Beil, Frank Timo; Gehrke, Thorsten; Pueschel, Klaus; Hahn, Michael; Rolvien, Tim Share Save
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Osteomodulin deficiency in mice causes a specific reduction of transversal cortical bone size Zhao, Wenbo; von Kroge, Simon; Jadzic, Jelena; Milovanovic, Petar; Sihota, Praveer; Luther, Julia; Brylka, Laura; von Brackel, Felix N.; Bockamp, Ernesto; Busse, Bjoern; Amling, Michael; Schinke, Thorsten; Yorgan, Timur A. Share Save
Alterations in compositional and cellular properties of the subchondral bone are linked to cartilage degeneration in hip osteoarthritis Delsmann, Julian; Eissele, Julian; Simon, Alexander; Alimy, Assil-Ramin; von Kroge, Simon; Mushumba, Herbert; Pueschel, Klaus; Busse, Bjoern; Ries, Christian; Amling, Michael; Beil, Frank Timo; Rolvien, Tim Share Save
Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development Brylka, Laura J.; Alimy, Assil-Ramin; Tschaffon-Mueller, Miriam E. A.; Jiang, Shan; Ballhause, Tobias Malte; Baranowsky, Anke; von Kroge, Simon; Delsmann, Julian; Pawlus, Eva; Eghbalian, Kian; Pueschel, Klaus; Schoppa, Astrid; Haffner-Luntzer, Melanie; Beech, David J.; Beil, Frank Timo; Amling, Michael; Keller, Johannes; Ignatius, Anita; Yorgan, Timur A.; Rolvien, Tim; Schinke, Thorsten Share Save
Mice heterozygous for an osteogenesis imperfecta-linked MBTPS2 variant display a compromised subchondral osteocyte lacunocanalicular network associated with abnormal articular cartilage Danyukova, Tatyana; Alimy, Assil-Ramin; Velho, Renata Voltolini; Yorgan, Timur A.; Di Lorenzo, Giorgia; von Kroge, Simon; Tidow, Henning; Wiegert, J. Simon; Hermans-Borgmeyer, Irm; Schinke, Thorsten; Rolvien, Tim; Pohl, Sandra Share Save
AXIN1 bi-allelic variants disrupting the C-terminal DIX domain cause craniometadiaphyseal osteosclerosis with hip dysplasia Terhal, Paulien; Venhuizen, Anton J.; Lessel, Davor; Tan, Wen-Hann; Alswaid, Abdulrahman; Gruen, Regina; Alzaidan, Hamad I.; von Kroge, Simon; Ragab, Nada; Hempel, Maja; Kubisch, Christian; Novais, Eduardo; Cristobal, Alba; Tripolszki, Kornelia; Bauer, Peter; Fischer-Zirnsak, Bjorn; Nievelstein, Rutger A. J.; van Dijk, Atty; Nikkels, Peter; Oheim, Ralf; Hahn, Heidi; Bertoli-Avella, Aida; Maurice, Madelon M.; Kornak, Uwe Share Save
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Effects of Infantile Hypophosphatasia on Human Dental Tissue Woelfel, Eva Maria; von Kroge, Simon; Matthies, Levi; Koehne, Till; Petz, Karin; Beikler, Thomas; Schmid-Herrmann, Carmen Ulrike; Kahl-Nieke, Baerbel; Tsiakas, Konstantinos; Santer, Rene; Muschol, Nicole Maria; Herrmann, Jochen; Busse, Bjoern; Amling, Michael; Rolvien, Tim; Jandl, Nico Maximilian; Barvencik, Florian Share Save
Catalysis-Independent ENPP1 Protein Signaling Regulates Mammalian Bone Mass Zimmerman, Kristin; Liu, Xiaochen; von Kroge, Simon; Stabach, Paul; Lester, Ethan R.; Chu, Emily Y.; Srivastava, Shivani; Somerman, Martha J.; Tommasini, Steven M.; Busse, Bjorn; Schinke, Thorsten; Carpenter, Thomas O.; Oheim, Ralf; Braddock, Demetrios T. Share Save
Impaired bone quality in the superolateral femoral neck occurs independent of hip geometry and bone mineral density Kroge, Simon Von; Sturznickel, Julian; Bechler, Ulrich; Stockhausen, Kilian Elia; Eissele, Julian; Hubert, Jan; Amling, Michael; Beil, Frank Timo; Busse, Bjorn; Rolvien, Tim Share Save
The WNT1G177C mutation specifically affects skeletal integrity in a mouse model of osteogenesis imperfecta type XV Vollersen, Nele; Zhao, Wenbo; Rolvien, Tim; Lange, Fabiola; Schmidt, Felix Nikolai; Sonntag, Stephan; Shmerling, Doron; von Kroge, Simon; Stockhausen, Kilian Elia; Sharaf, Ahmed; Schweizer, Michaela; Karsak, Meliha; Busse, Bjoern; Bockamp, Ernesto; Semler, Oliver; Amling, Michael; Oheim, Ralf; Schinke, Thorsten; Yorgan, Timur Alexander Share Save
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Response of the ENPP1-Deficient Skeletal Phenotype to Oral Phosphate Supplementation and/or Enzyme Replacement Therapy: Comparative Studies in Humans and Mice Ferreira, Carlos R.; Kavanagh, Dillon; Oheim, Ralf; Zimmerman, Kristin; Stuerznickel, Julian; Li, Xiaofeng; Stabach, Paul; Rettig, R. Luke; Calderone, Logan; MacKichan, Colin; Wang, Aaron; Hutchinson, Hunter A.; Nelson, Tracy; Tommasini, Steven M.; von Kroge, Simon; Fiedler, Imke A. K.; Lester, Ethan R.; Moeckel, Gilbert W.; Busse, Bjoern; Schinke, Thorsten; Carpenter, Thomas O.; Levine, Michael A.; Horowitz, Mark C.; Braddock, Demetrios T. Share Save
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