Not logged in 1552: FIRST EVALUATION OF A REAL-TIME REINFORCEMENT LEARNING DECISION SUPPORT SYSTEM FOR SEPSIS IN THE ICU Komorowski, Matthieu; Li, Luchen; El-kotob, Qamar; Festor, Paul; Nagendran, Myura; Ni, Melody; Buckle, Peter W; Miccoci, Massimo; Zamora Talaya, Maria Bernarda; Kettley-Linsell, Hannah; Fagbodun, Elizabeth O; Glampson, Ben; Harris, Steve; Brealey, David; Faisal, Aldo A; Gordon, Anthony Share Save
Views on consent approaches used in emergency and critical care research: a rapid, systematic review Mahon, Niamh; Hays, Leanne M. C.; Coy, Eva; Ainscough, Kate; Burrell, Aidan; Gordon, Anthony C.; Rochwerg, Bram; Wang, Chun-Mei; Harvey, Dan; Parekh, Dhruv; Goligher, Ewan; Toal, Fiona; Saito, Hiroki; Marshall, John C.; Stewart, Jonathan; Gobat, Nina; Webb, Steve; Tolppa, Timo; McAuley, Danny F.; Nichol, Alistair D. Share Save
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Dexmedetomidine- or Clonidine-Based Sedation Compared With Propofol in Critically Ill Patients: The A2B Randomized Clinical Trial Walsh, Timothy S.; Parker, Richard A.; Aitken, Leanne M.; McKenzie, Cathrine A.; Emerson, Lydia; Boyd, Julia; Macdonald, Alix; Beveridge, Gayle; Giddings, Annabel; Hope, David; Irvine, Sian; Tuck, Sharon; Lone, Nazir I.; Kydonaki, Kalliopi; Norrie, John; Brealey, David; Antcliffe, David; Reay, Michael; Williams, Alan; Bewley, Jeremy; Creagh-Brown, Benedict; McAuley, Daniel F.; Dark, Paul; Wise, Matt P.; Gordon, Anthony C.; Perkins, Gavin D.; Reade, Michael C.; Blackwood, Bronagh; MacLullich, Alasdair; Glen, Robert; Page, Valerie J.; Weir, Christopher J. Share Save
Tocilizumab, sarilumab and anakinra in critically ill patients with COVID-19: a randomised, controlled, open-label, adaptive platform trial Derde, Lennie; Gordon, Anthony C.; Mouncey, Paul R.; Al-Beidh, Farah; Rowan, Kathryn M.; Nichol, Alistair D.; Arabi, Yaseen M.; Annane, Djillali; Beane, Abigail; Beasley, Richard; Bonten, Marc J. M.; Bradbury, Charlotte A.; Brunkhorst, Frank M.; Buzgau, Adrian; Buxton, Meredith; Cheng, Allen C.; Cooper, Nicola; Cove, Matthew; Cremer, Olaf L.; Detry, Michelle A.; Duffy, Eamon J.; Estcourt, Lise J.; Fitzgerald, Mark; Galea, James; Goossens, Herman; Haniffa, Rashan; Hills, Thomas E.; Huang, David T.; Ichihara, Nao; King, Andrew; Lamontagne, Francois; Lawler, Patrick R.; Leavis, Helen L.; Lewis, Roger J.; Litton, Edward; Marshall, John C.; Mayr, Florian B.; McAuley, Daniel F.; McGlothlin, Anna; McGuinness, Shay P.; McVerry, Bryan J.; Morpeth, Susan C.; Murthy, Srinivas; Netea, Mihai G.; Orr, Katrina; Parke, Rachael L.; Parker, Jane C.; Patanwala, Asad E.; Pettila, Ville; Reyes, Luis Felipe; Saito, Hiroki; Santos, Marlene S.; Saunders, Christina T.; Seymour, Christopher W.; Shankar-Hari, Manu; Sligl, Wendy, I; Turgeon, Alexis F.; Turner, Anne M.; Tong, Steven Y. C.; Vaara, Suvi; Youngstein, Taryn; Zarychanski, Ryan; Green, Cameron; Higgins, Alisa M.; Mcarthur, Colin J.; Berry, Lindsay R.; Lorenzi, Elizabeth; Berry, Scott; Webb, Steve A.; Angus, Derek C.; van de Veerdonk, Frank L. Share Save
Digital innovation in healthcare: quantifying the impact of digital sepsis screening tools on patient outcomes-a multi-site natural experiment Honeyford, Kate; Timney, Alf; Lazzarino, Runa; Welch, John; Brent, Andrew Jonathan; Kinderlerer, Anne; Ghazal, Peter; Gordon, Anthony C.; Patil, Shashank; Cooke, Graham; Costelloe, Ceire E. Share Save
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The sepsis journey and where digital alerts can help: a qualitative, interview study with survivors and family members in England Lazzarino, Runa; Borek, Aleksandra J.; Brent, Andrew J.; Welch, John; Honeyford, Kate; Daniels, Ron; Kinderlerer, Anne; Cooke, Graham; Patil, Shashank; Gordon, Anthony; Goodman, Philippa; Glampson, Ben; Ghazal, Peter; Costelloe, Ceire; Tonkin-Crine, Sarah Share Save
Biomarker-Guided Antibiotic Duration for Hospitalized Patients With Suspected Sepsis Dark, Paul; Hossain, Anower; Mcauley, Daniel F.; Brealey, David; Carlson, Gordon; Clayton, Jonathan C.; Felton, Timothy W.; Ghuman, Belinder K.; Gordon, Anthony C.; Hellyer, Thomas P.; Lone, Nazir I.; Manazar, Uzma; Richards, Gillian; Mccullagh, Iain J.; Mcmullan, Ronan; Mcnamee, James J.; Mcneil, Hannah C.; Mouncey, Paul R.; Naisbitt, Micheal J.; Parker, Robert J.; Poole, Ruth L.; Rostron, Anthony J.; Singer, Mervyn; Stevenson, Matt D.; Walsh, Tim S.; Welters, Ingeborg D.; Whitehouse, Tony; Whiteley, Simon; Wilson, Peter; Young, Keith K.; Perkins, Gavin D.; Lall, Ranjit; ADAPT Sepsis Collaborators Share Save
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The effects of ultra-selective beta1-antagonism on the metabolic and cytokine profile in septic shock patients receiving noradrenaline: a sub-investigation from the STRESS-L Randomised Study Thomas, Jarrod L.; Mcgee, Kirsty C.; Hossain, Anower; Perkins, Gavin D.; Gordon, Anthony C.; Young, Duncan; McAuley, Danny; Singer, Mervyn; Lall, Ranjit; Kramaric, Tina; Lord, Janet M.; Whitehouse, Tony; Mur, Luis A. J. Share Save
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Developing Guidance for Donor Intervention Randomized Controlled Trials: Initial Discussions From the Canada-United Kingdom 2022 Workshop Slessarev, Marat; Bain, Katie L.; Basmaji, John; Blydt-Hansen, Tom D.; Cooper, Jessie; D'Aragon, Frederick; Del Sorbo, Lorenzo; Evans, Amy; Gordon, Anthony C.; Klein, Gail; Meade, Maureen O.; Murphy, Nicholas; Thomas, Helen L.; Weiss, Matthew J.; Weijer, Charles; Harvey, Dan Share Save
From ICU Syndromes to ICU Subphenotypes Consensus Report and Recommendations for Developing Precision Medicine in the ICU Gordon, Anthony C.; Alipanah-Lechner, Narges; Bos, Lieuwe D.; Dianti, Jose; Diaz, Janet V.; Finfer, Simon; Fujii, Tomoko; Giamarellos-Bourboulis, Evangelos J.; Goligher, Ewan C.; Gong, Michelle Ng; Karakike, Eleni; Liu, Vincent X.; Lumlertgul, Nuttha; Marshall, John C.; Menon, David K.; Meyer, Nuala J.; Munroe, Elizabeth S.; Myatra, Sheila N.; Ostermann, Marlies; Prescott, Hallie C.; Randolph, Adrienne G.; Schenck, Edward J.; Seymour, Christopher W.; Shankar-Hari, Manu; Singer, Mervyn; Smit, Marry R.; Tanaka, Aiko; Taccone, Fabio S.; Thompson, B. Taylor; Torres, Lisa K.; van der Poll, Tom; Vincent, Jean-Louis; Calfee, Carolyn S. Share Save
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Patient stratification using plasma cytokines and their regulators in sepsis: relationship to outcomes, treatment effect and leucocyte transcriptomic subphenotypes Antcliffe, David Benjamin; Mi, Yuxin; Santhakumaran, Shalini; Burnham, Katie L.; Prevost, A. Toby; Ward, Josie K.; Marshall, Timothy J.; Bradley, Claire; Al-Beidh, Farah; Hutton, Paula; McKechnie, Stuart; Davenport, Emma E.; Hinds, Charles J.; O'Kane, Cecilia M.; McAuley, Daniel Francis; Shankar-Hari, Manu; Gordon, Anthony C.; Knight, Julian C. Share Save
Adaptive multi-interventional trial platform to improve patient care for fibrotic interstitial lung diseases Kawano-Dourado, Leticia; Kulkarni, Tejaswini; Ryerson, Christopher J.; Rivera-Ortega, Pilar; Baldi, Bruno Guedes; Chaudhuri, Nazia; Funke-Chambour, Manuela; Hoffmann-Vold, Anna-Maria; Johannson, Kerri A.; Khor, Yet Hong; Montesi, Sydney B.; Piccari, Lucilla; Prosch, Helmut; Molina-Molina, Maria; Sellares Torres, Jacobo; Bauer-Ventura, Iazsmin; Rajan, Sujeet; Jacob, Joseph; Richards, Duncan; Spencer, Lisa G.; Wendelberger, Barbara; Jensen, Tom; Quintana, Melanie; Kreuter, Michael; Gordon, Anthony C.; Martinez, Fernando J.; Kaminski, Naftali; Cornelius, Victoria; Lewis, Roger; Adams, Wendy; Jenkins, Gisli Share Save
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