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I

Isidro Cortés‐Ciriano

wellcome sanger institute

55H-index
239Paper Count
2.5WCitation Count
Published Papers 58
Publication Date
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A tumour-derived organoid biobank maps cancer gene dependencies
errNature
IF48.5
err2026-08-05
err0
errOAAI
errC. Herranz-Ors; S. G. Bhosle; A. E. Beck; J. G. R. Gilbert; G. Picco; J. Espejo Valle-Inclan; F. Muyas; S. Valentini; A. E. Andres; R. Ansari; S. Barthorpe; G. Battarbee; C. M. Beaver; S. Brocklesby; J. Cantwell; C. A. Collins; J. Davis; H. G. Dimitrova; J. Doran; E. Efendi; K. Evans; M. Fekry; T. A. Fowler; M. Garcia-Casado; J. A. T. Griffiths; C. Hall; R. Hamer; C. Hardy; Z. Hewitson; E. Hitch; L. Holland; D. A. Jackson; N. Joshi; A. Kavasakali; L. Letchford; H. B. Lightfoot; H. Lingala; I. Mali; K. May; T. Mironenko; J. Morris; C. Pacini; S. Price; G. Robert-Tissot; H. A. Rogers; J. V. Smith; K. Smith; E. Souster; W. J. Spence; F. Thomas; S. F. Vieira; S. Walker; G. Alfonsin; H. Bermingham; H. Coles; D. P. Ennis; A. Freeman; G. Giannone; N. Grehan; E. A. Griffiths; J. Hall; S. L. Lee; E. Y. L. Leung; C. Loreno; C. Millington; A. Mirnezami; B. Nutzinger; K. Orzechowska; C. M. A. Pinna; A. M. Redmond; K. Roberts; S. Roy; D. A. Sanders; P. Taniere; M. Vias; K. Wanigasooriya; M. R. Stratton; L. M. Staudt; U. McDermott; J. D. Brenton; I. A. McNeish; A. Biankin; O. J. Sansom; I. Cortes-Ciriano; T. J. Underwood; R. C. Fitzgerald; A. D. Beggs; H. E. Francies; M. J. Garnett
errShare
errSave
Complex de novo structural variants are an underestimated cause of rare disorders
errNature Communications
IF15.7
err2025-11-03
err0
errOAAI
errHyunchul Jung; Tsun-Po Yang; Susan Walker; Petr Danecek; O. Isaac Garcia-Salinas; Matthew D. C. Neville; Joseph Christopher; Isidro Cortés-Ciriano; Helen Firth; Aylwyn Scally; Matthew Hurles; Peter Campbell; Raheleh Rahbari
errShare
errSave
Origins of chromosome instability unveiled by coupled imaging and genomics
errNature
IF48.5
err2025-10-29
err0
errOAAI
errMarco Raffaele Cosenza; Alice Gaiatto; Büşra Erarslan Uysal; Álvaro Andrades; Nina Luisa Sautter; Marina Simunovic; Michael Adrian Jendrusch; Sonia Zumalave; Tobias Rausch; Aliaksandr Halavatyi; Eva-Maria Geissen; Joshua Lucas Eigenmann; Thomas Weber; Patrick Hasenfeld; Eva Benito; Catherine Stober; Isidro Cortes-Ciriano; Andreas E. Kulozik; Rainer Pepperkok; Jan O. Korbel
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errSave
Stratified Medicine Paediatrics2-advancing precision medicine in paediatric cancer
errCANCER RESEARCH
IF16.6
err2024-09-05
err0
PREAI
errVedi, Aditi; George, Sally; Jacques, Thomas; Cortes-Ciriano, Isidro; Hubank, Michael; Beggs, Andrew; Cheang, Maggie; Porta, Nuria; Hutchinson, Ciaran; Hopkins, Louise; Bukhari, Amina; Barfoot, Regan; Clifford, Steve; O'Connor, David; Ritzmann, Timothy; Burke, Amos; Anderson, John; Hargrave, Darren; Chesler, Louis
errShare
errSave
Non-homologous end joining shapes the genomic rearrangement landscape of chromothripsis from mitotic errors
errNATURE COMMUNICATIONS
IF15.7
err2024-07-04
err1
errOAAI
errHu, Qing; Valle-Inclan, Jose Espejo; Dahiya, Rashmi; Guyer, Alison; Mazzagatti, Alice; Maurais, Elizabeth G.; Engel, Justin L.; Lu, Huiming; Davis, Anthony J.; Cortes-Ciriano, Isidro; Ly, Peter
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errSave
Evolutionary trajectories of complex genome rearrangements in osteosarcoma
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errCiriano, Isidro Cortes; Valle-Inclan, Jose Espejo; de Noon, Solange; Trevers, Katherine; Elrick, Hillary; Flanagan, Adrienne M.
errShare
errSave
Specialized replication mechanisms maintain genome stability at human centromeres
errMOLECULAR CELL
IF16.6
err2024-03-01
err2
PREAI
errScelfo, Andrea; Angrisani, Annapaola; Grillo, Marco; Barnes, Bethany M.; Muyas, Francesc; Sauer, Carolin M.; Leung, Chin Wei Brian; Dumont, Marie; Grison, Marine; Mazaud, David; Garnier, Mickael; Guintini, Laetitia; Nelson, Louisa; Esashi, Fumiko; Cortes-Ciriano, Isidro; Taylor, Stephen S.; Dejardin, Jerome; Wilhelm, Therese; Fachinetti, Daniele
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errSave
The ALT pathway generates telomere fusions that can be detected in the blood of cancer patients
errNATURE COMMUNICATIONS
IF15.7
err2024-01-02
err1
errOAAI
errMuyas, Francesc; Gomez Rodriguez, Manuel Jose; Cascao, Rita; Afonso, Angela; Sauer, Carolin M.; Faria, Claudia C.; Cortes-Ciriano, Isidro; Flores, Ignacio
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errSave
The landscape of human SVA retrotransposons
errNUCLEIC ACIDS RESEARCH
IF13.1
err2023-10-12
err4
errOAAI
errChu, Chong; Lin, Eric W.; Tran, Antuan; Jin, Hu; Ho, Natalie, I; Veit, Alexander; Cortes-Ciriano, Isidro; Burns, Kathleen H.; Ting, David T.; Park, Peter J.
errShare
errSave
Mismatch repair deficiency is not sufficient to elicit tumor immunogenicity
errNATURE GENETICS
IF31.8
err2023-09-14
err46
errOAAI
errWestcott, Peter M. K.; Muyas, Francesc; Hauck, Haley; Smith, Olivia C.; Sacks, Nathan J.; Ely, Zackery A.; Jaeger, Alex M.; Rideout, William M., III; Zhang, Daniel; Bhutkar, Arjun; Beytagh, Mary C.; Canner, David A.; Jaramillo, Grissel C.; Bronson, Roderick T.; Naranjo, Santiago; Jin, Abbey; Patten, J. J.; Cruz, Amanda M.; Shanahan, Sean-Luc; Cortes-Ciriano, Isidro; Jacks, Tyler
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errSave
Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy
errCELL REPORTS MEDICINE
IF10.6
err2023-09-01
err7
errOAAI
errHeidegger, Simon; Stritzke, Florian; Dahl, Sarah; Dassler-Plenker, Juliane; Joachim, Laura; Buschmann, Dominik; Fan, Kaiji; Sauer, Carolin M.; Ludwig, Nils; Winter, Christof; Enssle, Stefan; Li, Suqi; Perl, Markus; Goergens, Andre; Haas, Tobias; Orberg, Erik Thiele; Goettert, Sascha; Woelfel, Catherine; Engleitner, Thomas; Cortes-Ciriano, Isidro; Rad, Roland; Herr, Wolfgang; Giebel, Bernd; Ruland, Jurgen; Bassermann, Florian; Coch, Christoph; Hartmann, Gunther; Poeck, Hendrik
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errSave
Highlights from the 1st European cancer dependency map symposium and workshop
errFEBS LETTERS
IF3
err2023-07-24
err2
errOAAI
errTrastulla, Lucia; Savino, Aurora; Beltrao, Pedro; Ciriano, Isidro Cortes; Fenici, Peter; Garnett, Mathew J. J.; Guerini, Ilaria; Bigas, Nuria Lopez; Mattaj, Iain; Petsalaki, Evangelia; Riva, Laura; Tape, Christopher J. J.; Sharma, Sumana; Vazquez, Francisca; Iorio, Francesco
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errSave
De novo detection of somatic mutations in high-throughput single-cell profiling data sets
errNATURE BIOTECHNOLOGY
IF41.7
err2023-07-06
err22
errOAAI
errMuyas, Francesc; Sauer, Carolin M.; Valle-Inclan, Jose Espejo; Li, Ruoyan; Rahbari, Raheleh; Mitchell, Thomas J.; Hormoz, Sahand; Cortes-Ciriano, Isidro
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errSave
SAVANA: a computational method to characterize structural variation in human cancer genomes using nanopore sequencing
errCANCER RESEARCH
IF16.6
err2023-04-14
err1
PREAI
errElrick, Hillary; Valle-Inclan, Jose Espejo; Trevers, Katherine E.; Muyas, Francesc; Cascao, Rita; Afonso, Angela; Faria, Claudia C.; Flanagan, Adrienne M.; Cortes-Ciriano, Isidro
errShare
errSave
MSI cancer associated DNA (TA)n-dinucleotide repeat expansions and implications for Werner synthetic lethality
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errPicco, Gabriele; Bhosle, Shriram; Kalyva, Maria; Grassi, Elena; Gibson, Freddy; Al Saedi, Angham; Vieira, Sara; Sanders, Mathijs; Trusolino, Livio; Bertotti, Andrea; Mathew, Isidro Cortes-Ciriano
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errSave
Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing (vol 52, pg 331, 2020)
errNATURE GENETICS
IF31.8
err2023-03-21
err1
errOAAI
errCortes-Ciriano, Isidro; Lee, Jake June-Koo; Xi, Ruibin; Jain, Dhawal; Jung, Youngsook L.; Yang, Lixing; Gordenin, Dmitry; Klimczak, Leszek J.; Zhang, Cheng-Zhong; Pellman, David S.; Park, Peter J.
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errSave
Profilin 1 deficiency drives mitotic defects and reduces genome stability
errCOMMUNICATIONS BIOLOGY
IF5.1
err2023-01-04
err5
errOAAI
errdi Carlo, Federica Scotto; Russo, Sharon; Muyas, Francesc; Mangini, Maria; Garribba, Lorenza; Pazzaglia, Laura; Genesio, Rita; Biamonte, Flavia; De Luca, Anna Chiara; Santaguida, Stefano; Scotlandi, Katia; Cortes-Ciriano, Isidro; Gianfrancesco, Fernando
errShare
errSave
Genomic Patterns of Malignant Peripheral Nerve Sheath Tumor (MPNST) Evolution Correlate with Clinical Outcome and Are Detectable in Cell-Free DNA
errCANCER DISCOVERY
IF33.3
err2023-01-04
err32
errOAAI
errCortes-Ciriano, Isidro; Steele, Christopher D.; Piculell, Katherine; Al-Ibraheemi, Alyaa; Eulo, Vanessa; Bui, Marilyn M.; Chatzipli, Aikaterini; Dickson, Brendan C.; Borcherding, Dana C.; Feber, Andrew; Galor, Alon; Hart, Jesse; Jones, Kevin B.; Jordan, Justin T.; Kim, Raymond H.; Lindsay, Daniel; Miller, Colin; Nishida, Yoshihiro; Proszek, Paula Z.; Serrano, Jonathan; Sundby, Taylor; Szymanski, Jeffrey J.; Ullrich, Nicole J.; Viskochil, David; Wang, Xia; Snuderl, Matija; Park, Peter J.; Flanagan, Adrienne M.; Hirbe, Angela C.; Pillay, Nischalan; Miller, David T.
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errSave
Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer (Dec, 10.1038/s41467-019-13824-9, 2022)
errNATURE COMMUNICATIONS
IF15.7
err2022-12-08
err0
errOAAI
errSieverling, Lina; Hong, Chen; Koser, Sandra D.; Ginsbach, Philip; Kleinheinz, Kortine; Hutter, Barbara; Braun, Delia M.; Cortes-Ciriano, Isidro; Xi, Ruibin; Kabbe, Rolf; Park, Peter J.; Eils, Roland; Schlesner, Matthias; Brors, Benedikt; Rippe, Karsten; Jones, David T. W.; Feuerbach, Lars
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errSave
Clonal diversification and histogenesis of malignant germ cell tumours
errNATURE COMMUNICATIONS
IF15.7
err2022-08-11
err9
errOAAI
errOliver, Thomas R. W.; Chappell, Lia; Sanghvi, Rashesh; Deighton, Lauren; Ansari-Pour, Naser; Dentro, Stefan C.; Young, Matthew D.; Coorens, Tim H. H.; Jung, Hyunchul; Butler, Tim; Neville, Matthew D. C.; Leongamornlert, Daniel; Sanders, Mathijs A.; Hooks, Yvette; Cagan, Alex; Mitchell, Thomas J.; Cortes-Ciriano, Isidro; Warren, Anne Y.; Wedge, David C.; Heer, Rakesh; Coleman, Nicholas; Murray, Matthew J.; Campbell, Peter J.; Rahbari, Raheleh; Behjati, Sam
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Research Directions

The data has not been retrieved yet.
Co-authors
Cooperation Journals
M
Mark Gerstein
H-index: 191 · Papers: 1.2K
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Marco A. Marra
H-index: 190 · Papers: 1.3K
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Steven J.M. Jones
H-index: 189 · Papers: 1.3K
M
Michael R. Stratton
H-index: 179 · Papers: 644
D
David Haussler
H-index: 175 · Papers: 721
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