Owen N. Witte - Publications, H-index & Citations

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Owen N. Witte

los angeles (ucla)

122H-index

760Paper Count

4.8WCitation Count

Published Papers 173

Publication Date

David Baltimore (1938–2025)

Nature Biotechnology

IF41.7

2025-12-08

PREAI

Lili Yang; Antoni Ribas; Owen N. Witte

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Transcriptional profiling clarifies a program of enzalutamide extreme non-response in lethal prostate cancer

npj Precision Oncology

IF8

2025-07-07

OAAI

Anbarasu Kumaraswamy; Ya-Mei Hu; Joel A. Yates; Chao Zhang; Eva Rodansky; Dhruv Khokhani; Diana Flores; Zhi Duan; Yi Zhang; Shaadi Tabatabaei; Rachel Slottke; Shangyuan Ye; Primo Lara; Adam Foye; Charles J. Ryan; David A. Quigley; Jiaoti Huang; Rahul Aggarwal; Robert E. Reiter; Max S. Wicha; Tomasz M. Beer; Matthew Rettig; Martin Gleave; Christopher P. Evans; Owen N. Witte; Joshua M. Stuart; George V. Thomas; Felix Y. Feng; Eric J. Small; Zheng Xia; Joshi J. Alumkal

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PGC-1α drives small cell neuroendocrine cancer progression toward an ASCL1-expressing subtype with increased mitochondrial capacity

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-11-26

OAAI

Varuzhanyan, Grigor; Chen, Chia-Chun; Freeland, Jack; He, Tian; Tran, Wendy; Song, Kai; Wang, Liang; Cheng, Donghui; Xu, Shili; Dibernardo, Gabriella A.; Esedebe, Favour N.; Bhatia, Vipul; Han, Mingqi; Abt, Evan R.; Park, Jung Wook; Memarzadeh, Sanaz; Shackelford, David B.; Lee, John K.; Graeber, Thomas G.; Shirihai, Orian S.; Witte, Owen N.

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Staggered immunization with mRNA vaccines encoding SARS- CoV-2 polymerase or spike antigens broadens the T cell epitope repertoire

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-11-26

OAAI

Abt, Evan R.; Lam, Alex K.; Noguchi, Miyako; Rashid, Khalid; Mclaughlin, Jami; Teng, Pu - Lin; Tran, Wendy; Cheng, Donghui; Nesterenko, Pavlo A.; Mao, Zhiyuan; Creech, Amanda L.; Sojo, Giselle Burton; Jeyachandran, Arjit Vijey; Tam, Ying K.; Henley, Jill E.; Comai, Lucio; Pardi, Norbert; Arumugaswami, Vaithilingaraja; Witte, Owen N.; Radu, Caius G.; Wu, Ting- Ting

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Defining T cell receptor repertoires using nanovial-based binding and functional screening

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-03-27

OAAI

Koo, Doyeon; Mao, Zhiyuan; Dimatteo, Robert; Noguchi, Miyako; Tsubamoto, Natalie; McLaughlin, Jami; Tran, Wendy; Lee, Sohyung; Cheng, Donghui; de Rutte, Joseph; Sojo, Giselle Burton; Witte, Owen N.; Di Carlo, Dino

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Dual- inhibitory domain iCARs improve the efficiency of the AND- NOT gate CAR T strategy

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-11-14

OAAI

Bangayan, Nathanael J.; Wang, Liang; Sojo, Giselle Burton; Noguchi, Miyako; Cheng, Donghui; Ta, Lisa; Gunn, Donny; Mao, Zhiyuan; Liu, Shiqin; Yin, Qingqing; Riedinger, Mireille; Li, Keyu; Wu, Anna M.; Stoyanova, Tanya; Witte, Owen N.

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The RNA- binding proteins hnRNP H and F regulate splicing of a MYC- dependent HRAS exon in prostate cancer cells

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-07-03

OAAI

Chena, Xinyuan; Yang, Harry Taegyun; Zhang, Beatrice; Phillips, John W.; Cheng, Donghui; Rigo, Frank; Witte, Owen N.; Xing, Yi; Black, Douglas L.

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The Genomic and Epigenomic Landscape of Double-Negative Metastatic Prostate Cancer

CANCER RESEARCH

IF16.6

2023-06-08

OAAI

Lundberg, Arian; Zhang, Meng; Aggarwal, Rahul; Li, Haolong; Zhang, Li; Foye, Adam; Sjostrom, Martin; Chou, Jonathan; Chang, Kevin; Moreno-Rodriguez, Thaidy; Shrestha, Raunak; Baskin, Avi; Zhu, Xiaolin; Weinstein, Alana S.; Younger, Noah; Alumkal, Joshi J.; Beer, Tomasz M.; Chi, Kim N.; Evans, Christopher P.; Gleave, Martin; Lara, Primo N.; Reiter, Rob E.; Retting, Matthew B.; Witte, Owen N.; Wyatt, Alexander W.; Feng, Felix Y.; Small, Eric J.; Quigley, David A.

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Genomic and epigenomic drivers of double-negative metastatic prostate cancer

CANCER RESEARCH

IF16.6

2023-06-02

PREAI

Lundberg, Arian; Zhang, Meng; Aggarwal, Rahul R.; Li, Haolong; Zhang, Li; Foye, Adam; Sjostrom, Martin; Chou, Jonathan; Chang, Kevin; Moreno-Rodriguez, Thaidy; Shrestha, Raunak; Baskin, Avi; Zhu, Xiaolin; Weinstein, Alana S.; Younger, Noah; Alumkal, Joshi J.; Beer, Tomasz M.; Chi, Kim N.; Evans, Christopher P.; Gleave, Martin; Lara, Primo N.; Reiter, Robert E.; Rettig, Matthew B.; Witte, Owen N.; Wyatt, Alexander W.; Feng, Felix Y.; Small, Eric J.; Quigley, David A.

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IRIS: Discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-05-16

OAAI

Pan, Yang; Phillips, John W.; Zhang, Beatrice D.; Noguchi, Miyako; Kutschera, Eric; McLaughlin, Jami; Nesterenko, Pavlo A.; Mao, Zhiyuan; Bangayan, Nathanael J.; Wang, Robert; Tran, Wendy; Yang, Harry T.; Wang, Yuanyuan; Xu, Yang; Obusan, Matthew B.; Cheng, Donghui; Lee, Alex H.; Kadash-Edmondson, Kathryn E.; Champhekar, Ameya; Puig-Saus, Cristina; Ribas, Antoni; Prins, Robert M.; Seet, Christopher S.; Crooks, Gay M.; Witte, Owen N.; Xing, Yi

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Development of adoptive T-cell therapies to target heterogeneity of mCRPC

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Lopez, Lupita S.; Bangayan, Nathanael; Witte, Owen; Priceman, Saul J.

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Normal immune development and glucocorticoid-induced thymocyte apoptosis in mice deficient for the T-Cell death-associated gene 8 receptor

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Radu, CG; Cheng, DH; Nijagal, A; Riedinger, M; McLaughlin, J; Yang, LV; Johnson, J; Witte, ON

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Vascular abnormalities in mice deficient for the G protein-coupled receptor GPR4 that functions as a pH sensor

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

112

OAAI

Yang, Li V.; Radu, Caius G.; Roy, Meenakshi; Lee, Sunyoung; McLaughlin, Jami; Teitell, Michael A.; Iruela-Arispe, M. Luisa; Witte, Owen N.

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Clinical Targeting of Mutated and Wild-Type Protein Tyrosine Kinases in Cancer

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Drake, Justin M.; Lee, John K.; Witte, Owen N.

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The 5-Hydroxymethylcytosine Landscape of Prostate Cancer

CANCER RESEARCH

IF16.6

2022-10-17

OAAI

Sjostrom, Martin; Zhao, Shuang G.; Levy, Samuel; Zhang, Meng; Ning, Yuhong; Shrestha, Raunak; Lundberg, Arian; Herberts, Cameron; Foye, Adam; Aggarwal, Rahul; Hua, Junjie T.; Li, Haolong; Bergamaschi, Anna; Maurice-Dror, Corinne; Maheshwari, Ashutosh; Chen, Sujun; Ng, Sarah W. S.; Ye, Wenbin; Petricca, Jessica; Fraser, Michael; Chesner, Lisa; Perry, Marc D.; Moreno-Rodriguez, Thaidy; Chen, William S.; Alumkal, Joshi J.; Chou, Jonathan; Morgans, Alicia K.; Beer, Tomasz M.; Thomas, George, V; Gleave, Martin; Lloyd, Paul; Phillips, Tierney; McCarthy, Erin; Haffner, Michael C.; Zoubeidi, Amina; Annala, Matti; Reiter, Robert E.; Rettig, Matthew B.; Witte, Owen N.; Fong, Lawrence; Bose, Rohit; Huang, Franklin W.; Luo, Jianhua; Bjartell, Anders; Lang, Joshua M.; Mahajan, Nupam P.; Lara, Primo N.; Evans, Christopher P.; Tran, Phuoc T.; Posadas, Edwin M.; He, Chuan; Cui, Xiao-Long; Huang, Jiaoti; Zwart, Wilbert; Gilbert, Luke A.; Maher, Christopher A.; Boutros, Paul C.; Chi, Kim N.; Ashworth, Alan; Small, Eric J.; He, Housheng H.; Wyatt, Alexander W.; Quigley, David A.; Feng, Felix Y.

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Transcriptional profiling of matched patient biopsies clarifies molecular determinants of enzalutamide-induced lineage plasticity

NATURE COMMUNICATIONS

IF15.7

2022-09-15

OAAI

Westbrook, Thomas C.; Guan, Xiangnan; Rodansky, Eva; Flores, Diana; Liu, Chia Jen; Udager, Aaron M.; Patel, Radhika A.; Haffner, Michael C.; Hu, Ya-Mei; Sun, Duanchen; Beer, Tomasz M.; Foye, Adam; Aggarwal, Rahul; Quigley, David A.; Youngren, Jack F.; Ryan, Charles J.; Gleave, Martin; Wang, Yuzhuo; Huang, Jiaoti; Coleman, Ilsa; Morrissey, Colm; Nelson, Peter S.; Evans, Christopher P.; Lara, Primo; Reiter, Robert E.; Witte, Owen; Rettig, Matthew; Wong, Christopher K.; Weinstein, Alana S.; Uzunangelov, Vlado; Stuart, Josh M.; Thomas, George, V; Feng, Felix Y.; Small, Eric J.; Yates, Joel A.; Xia, Zheng; Alumkal, Joshi J.

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Physical and in silico immunopeptidomic profiling of a cancer antigen prostatic acid phosphatase reveals targets enabling TCR isolation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-07-25

OAAI

Mao, Zhiyuan; Nesterenko, Pavlo A.; McLaughlin, Jami; Deng, Weixian; Sojo, Giselle Burton; Cheng, Donghui; Noguchi, Miyako; Chour, William; DeLucia, Diana C.; Finton, Kathryn A.; Qin, Yu; Obusan, Matthew B.; Tran, Wendy; Wang, Liang; Bangayan, Nathanael J.; Ta, Lisa; Chen, Chia-Chun; Seet, Christopher S.; Crooks, Gay M.; Phillips, John W.; Heath, James R.; Strong, Roland K.; Lee, John K.; Wohlschlegel, James A.; Witte, Owen N.

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HLA-A*02:01 restricted T cell receptors against the highly conserved SARS-CoV-2 polymerase cross-react with human coronaviruses

CELL REPORTS

IF6.9

2021-12-01

OAAI

Nesterenko, Pavlo A.; McLaughlin, Jami; Tsai, Brandon L.; Sojo, Giselle Burton; Cheng, Donghui; Zhao, Daniel; Mao, Zhiyuan; Bangayan, Nathanael J.; Obusan, Matthew B.; Su, Yapeng; Ng, Rachel H.; Chour, William; Xie, Jingyi; Li, Yan-Ruide; Lee, Derek; Noguchi, Miyako; Carmona, Camille; Phillips, John W.; Kim, Jocelyn T.; Yang, Lili; Heath, James R.; Boutros, Paul C.; Witte, Owen N.

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RNA Dysregulation: An Expanding Source of Cancer Immunotherapy Targets

TRENDS IN PHARMACOLOGICAL SCIENCES

IF19.9

2021-04-01

OAAI

Pan, Yang; Kadash-Edmondson, Kathryn E.; Wang, Robert; Phillips, John; Liu, Song; Ribas, Antoni; Aplenc, Richard; Witte, Owen N.; Xing, Yi

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Droplet-based mRNA sequencing of fixed and permeabilized cells by CLInt-seq allows for antigen-specific TCR cloning

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-01-11

OAAI

Nesterenko, Pavlo A.; McLaughlin, Jami; Cheng, Donghui; Bangayan, Nathanael J.; Sojo, Giselle Burton; Seet, Christopher S.; Qin, Yu; Mao, Zhiyuan; Obusan, Matthew B.; Phillips, John W.; Witte, Owen N.

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Research Directions