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D

Diane P. Hanger

university of london

56H-index
171Paper Count
1.3WCitation Count
Published Papers 63
Publication Date
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Proteomic analysis links truncated tau to lysosome motility, autophagy, and endo-lysosomal dysfunction
errAlzheimer's & Dementia
IF0
err2025-12-15
err0
errOAAI
errDespoina Goniotaki; Maximilian Hausherr; Steven Lynham; Ayushin Ale; George Chennell; Stefania Marcotti; Katrin Marcus; Wendy Noble; Diane P. Hanger; Graham Fraser; Deepak P. Srivastava
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Truncated tau interferes with the autophagy and endolysosomal pathway and results in lipid accumulation
errCELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
err2024-07-15
err0
errOAAI
errPollack, Saskia J.; Dakkak, Dina; Guo, Tong; Chennell, George; Gomez-Suaga, Patricia; Noble, Wendy; Jimenez-Sanchez, Maria; Hanger, Diane P.
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errSave
Tau-mediated synaptic dysfunction is coupled with HCN channelopathy
errALZHEIMERS & DEMENTIA
IF11.1
err2024-07-12
err0
errOAAI
errGoniotaki, Despoina; Tamagnini, Francesco; Biasetti, Luca; Rumpf, Svenja-Lotta; Troakes, Claire; Pollack, Saskia J.; Ukwesa, Shalom; Sun, Haoyue; Kraev, Igor; Serpell, Louise C.; Noble, Wendy; Staras, Kevin; Hanger, Diane P.
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errSave
Reactive astrocytes secrete the chaperone HSPB1 to mediate neuroprotection
errSCIENCE ADVANCES
IF12.5
err2024-03-22
err4
errOAAI
errYang, Fangjia; Beltran-Lobo, Paula; Sung, Katherine; Goldrick, Caoimhe; Croft, Cara L.; Nishimura, Agnes; Hedges, Erin; Mahiddine, Farah; Troakes, Claire; Golde, Todd E.; Perez-Nievas, Beatriz G.; Hanger, Diane P.; Noble, Wendy; Jimenez-Sanchez, Maria
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errSave
Expression of Concern: Molecular motors implicated in the axonal transport of tau and α-synuclein
errJOURNAL OF CELL SCIENCE
IF3.6
err2024-02-12
err0
errOAAI
errUtton, Michelle A.; Noble, Wendy J.; Hill, Josephine E.; Anderton, Brian H.; Hanger, Diane P.
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errSave
P2X7R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes
errBRAIN BEHAVIOR AND IMMUNITY
IF7.6
err2023-11-01
err5
errOAAI
errBeltran-Lobo, Paula; Hughes, Martina M.; Troakes, Claire; Croft, Cara L.; Rupawala, Huzefa; Jutzi, Daniel; Ruepp, Marc-David; Jimenez-Sanchez, Maria; Perkinton, Michael S.; Kassiou, Michael; Golde, Todd E.; Hanger, Diane P.; Verkhratsky, Alexei; Perez-Nievas, Beatriz G.; Noble, Wendy
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errSave
Barcodes distinguishing morphology of neuronal tauopathy
errPHYSICAL REVIEW RESEARCH
IF4.2
err2023-10-04
err0
errOAAI
errBeers, David; Goniotaki, Despoina; Hanger, Diane P.; Goriely, Alain; Harrington, Heather A.
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Artificial intelligence for neurodegenerative experimental models
errALZHEIMERS & DEMENTIA
IF11.1
err2023-09-28
err3
errOAAI
errMarzi, Sarah J.; Schilder, Brian M.; Nott, Alexi; Frigerio, Carlo Sala; Willaime-Morawek, Sandrine; Bucholc, Magda; Hanger, Diane P.; James, Charlotte; Lewis, Patrick A.; Lourida, Ilianna; Noble, Wendy; Rodriguez-Algarra, Francisco; Sharif, Jalil-Ahmad; Tsalenchuk, Maria; Winchester, Laura M.; Yaman, Umran; Yao, Zhi; Ranson, Janice M.; Llewellyn, David J.
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The disease associated Tau35 fragment has an increased propensity to aggregate compared to full-length tau (vol 8, 779240, 2021)
errFRONTIERS IN MOLECULAR BIOSCIENCES
IF4
err2023-09-15
err0
errOAAI
errLyu, Chen; Da Vela, Stefano; Al-Hilaly, Youssra; Marshall, Karen E.; Thorogate, Richard; Svergun, Dmitri; Serpell, Louise C.; Pastore, Annalisa; Hanger, Diane P.
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The Disease Associated Tau35 Fragment has an Increased Propensity to Aggregate Compared to Full-Length Tau
errFRONTIERS IN MOLECULAR BIOSCIENCES
IF4
err2021-10-28
err8
errOAAI
errLyu, Chen; Da Vela, Stefano; Al-Hilaly, Youssra; Marshall, Karen E.; Thorogate, Richard; Svergun, Dmitri; Serpell, Louise C.; Pastore, Annalisa; Hanger, Diane P.
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errSave
Editorial: Tau Propagation Mechanisms: Cell Models, Animal Models, and Beyond
errFRONTIERS IN NEUROSCIENCE
IF3.2
err2020-05-19
err2
errOAAI
errMotoi, Yumiko; Hanger, Diane P.; Hasegawa, Masato
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Bridging integrator 1 protein loss in Alzheimer's disease promotes synaptic tau accumulation and disrupts tau release
errBRAIN COMMUNICATIONS
IF4.5
err2020-02-14
err16
errOAAI
errGlennon, Elizabeth B.; Lau, Dawn H. W.; Gabriele, Rebecca M. C.; Taylor, Matthew F.; Troakes, Claire; Opie-Martin, Sarah; Elliott, Christina; Killick, Richard; Hanger, Diane P.; Perez-Nievas, Beatriz G.; Noble, Wendy
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errSave
Considerations for future tau-targeted therapeutics: can they deliver?
errEXPERT OPINION ON DRUG DISCOVERY
IF4.9
err2019-10-29
err12
errOAAI
errNoble, Wendy; Jimenez-Sanchez, Maria; Perez-Nievas, Beatriz G.; Hanger, Diane P.
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errSave
A pathogenic tau fragment compromises microtubules, disrupts insulin signaling and induces the unfolded protein response
errACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
err2019-01-03
err17
errOAAI
errGuo, Tong; Dakkak, Dina; Rodriguez-Martin, Teresa; Noble, Wendy; Hanger, Diane P.
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errSave
Characterisation of tau in the human and rodent enteric nervous system under physiological conditions and in tauopathy
errACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
err2018-07-23
err37
errOAAI
errLionnet, Arthur; Wade, Matthew A.; Corbille, Anne-Gaelle; Prigent, Alice; Paillusson, Sebastien; Tasselli, Maddalena; Gonzales, Jacques; Durieu, Emilie; Rolli-Derkinderen, Malvyne; Coron, Emmanuel; Duchalais, Emilie; Neunlist, Michel; Perkinton, Michael S.; Hanger, Diane P.; Noble, Wendy; Derkinderen, Pascal
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errSave
A new TAO kinase inhibitor reduces tau phosphorylation at sites associated with neurodegeneration in human tauopathies
errACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
err2018-05-07
err45
errOAAI
errGiacomini, Caterina; Koo, Chuay-Yeng; Yankova, Natalia; Tavares, Ignatius A.; Wray, Selina; Noble, Wendy; Hanger, Diane P.; Morris, Jonathan D. H.
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errSave
Hippocampal neurophysiology is modified by a disease-associated C-terminal fragment of tau protein
errNEUROBIOLOGY OF AGING
IF3.5
err2017-12-01
err24
errOAAI
errTamagnini, Francesco; Walsh, Darren A.; Brown, Jon T.; Bondulich, Marie K.; Hanger, Diane P.; Randall, Andrew D.
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errSave
Inhibition of glycogen synthase kinase-3 by BTA-EG4 reduces tau abnormalities in an organotypic brain slice culture model of Alzheimer's disease
errSCIENTIFIC REPORTS
IF3.9
err2017-08-07
err20
errOAAI
errCroft, Cara L.; Kurbatskaya, Ksenia; Hanger, Diane P.; Noble, Wendy
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errSave
Roles of tau protein in health and disease
errACTA NEUROPATHOLOGICA
IF9.3
err2017-04-06
err727
errOAAI
errGuo, Tong; Noble, Wendy; Hanger, Diane P.
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errSave
α-Synuclein binds to the ER-mitochondria tethering protein VAPB to disrupt Ca2+ homeostasis and mitochondrial ATP production
errACTA NEUROPATHOLOGICA
IF9.3
err2017-03-23
err290
errOAAI
errPaillusson, Sebastien; Gomez-Suaga, Patricia; Stoica, Radu; Little, Daniel; Gissen, Paul; Devine, Michael J.; Noble, Wendy; Hanger, Diane P.; Miller, Christopher C. J.
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Research Directions

No research directions
Co-authors
Cooperation Journals
A
Andrew J. Lees
H-index: 165 · Papers: 1.2K
N
Nicholas Wood
H-index: 139 · Papers: 1.1W
A
Alexei Verkhratsky
H-index: 122 · Papers: 815
T
Todd E. Golde
H-index: 110 · Papers: 537
C
Christopher E. Shaw
H-index: 105 · Papers: 492
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