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Nathalie Hinfray

ineris

20H-index
80Paper Count
1.3KCitation Count
Published Papers 22
Publication Date
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Physiologically based kinetics and toxicodynamic (PBK-TD) modelling in zebrafish embryos: A novel approach to assess endocrine disrupting chemicals acting on brain aromatase
errComputational Toxicology
IF2.9
err2026-05-28
err0
errOAAI
errRémy Beaudouin; Florian Geffroy; Karyn Le Menach; Hélène Budzinski; Cleo Bodin; Romain Dussauçoy; Benjamin Piccini; Edith Chadili; Nathalie Hinfray; François Brion; Pierre-André Billat
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An Integrated Approach Combining Regulatory Tests in tg(cyp19a1b:GFP) Zebrafish Embryos to Assess Toxicity; Developmental Effects; and Estrogenic Activity of Chemicals: A Case Study with Bisphenol A Substitutes
errENVIRONMENTAL SCIENCE & TECHNOLOGY
IF11.3
err2026-04-10
err0
errOAAI
errFlorian Geffroy; Armelle Christophe; Benjamin Piccini; Nathalie Hinfray; Edith Chadili; Emmanuelle Maillot-Marechal; Xavier Cousin; Mélanie Blanc-Legendre; Thierry D. Charlier; Pascal Pandard; Selim Aït-Aïssa; François Brion
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A new alternative method using cyp3a65 expression in transgenic zebrafish embryos to assess metabolic endocrine-disrupting chemicals in the intestine
errEnvironment International
IF9.7
err2025-10-17
err0
errOAAI
errChedi Erradhouani; Florian Geffroy; Benjamin Piccini; Nathalie Hinfray; Edith Chadili; Patrick Balaguer; Frédéric Sohm; Selim Aït-Aïssa; Xavier Coumoul; François Brion
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Endocrine effects of Imazalil on aromatase expression, vitellogenesis and ovarian histology using cyp19a1a-eGFP-casper transgenic zebrafish
errAquatic Toxicology
IF4.3
err2025-09-17
err0
PREAI
errJulie De Oliveira; Tu-Ky Ly; Edith Chadili; Violette Thermes; Antoine Mergot; Benjamin Piccini; Olivier Palluel; Hélène Budzinski; Karyn Le Menach; Patrick Pardon; Rémy Beaudouin; Xavier Cousin; François Brion; Nathalie Hinfray
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PBK-TD modelling of the gonadotropic axis: Case study with two azole fungicides in female zebrafish
errAQUATIC TOXICOLOGY
IF4.3
err2025-06-01
err0
PREAI
errLy, Tu-Ky; Chadili, Edith; Palluel, Olivier; Le Menach, Karyn; Budzinski, Helene; Tebby, Cleo; Hinfray, Nathalie; Beaudouin, Remy
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Exploring BPA alternatives - Environmental levels and toxicity review
errENVIRONMENT INTERNATIONAL
IF9.7
err2024-07-01
err7
errOAAI
errAdamovsky, Ondrej; Groh, Ksenia J.; Bialk-Bielinska, Anna; Escher, Beate I.; Beaudouin, R.; Lagares, Liadys Mora; Tollefsen, Knut Erik; Fenske, Martina; Mulkiewicz, Ewa; Creusot, Nicolas; Sosnowska, Anita; Loureiro, Susana; Beyer, Jonny; Repetto, Guillermo; Stern, Alja; Lopes, Isabel; Monteiro, Marta; Zikova-Kloas, Andrea; Elersek, Tina; Vracko, Marjan; Zdybel, Szymon; Puzyn, Tomasz; Koczur, Weronika; Morthorst, Jane Ebsen; Holbech, Henrik; Carlsson, Gunnar; Orn, Stefan; Herrero, Oscar; Siddique, Ayesha; Liess, Matthias; Braun, Georg; Srebny, Vanessa; Zegura, Bojana; Hinfray, Nathalie; Brion, Francois; Knapen, Dries; Vandeputte, Ellen; Stinckens, Evelyn; Vergauwen, Lucia; Behrendt, Lars; Silva, Maria Joa; Blaha, Ludek; Kyriakopoulou, Katerina
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An end-to-end pipeline based on open source deep learning tools for reliable analysis of complex 3D images of ovaries
errDEVELOPMENT
IF3.6
err2023-04-03
err2
errOAAI
errLesage, Manon; Thomas, Manon; Pecot, Thierry; Ly, Tu -Ky; Hinfray, Nathalie; Beaudouin, Remy; Neumann, Michelle; Lovell-Badge, Robin; Bugeon, Jerome; Thermes, Violette
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Refinement of an OECD test guideline for evaluating the effects of endocrine disrupting chemicals on aromatase gene expression and reproduction using novel transgenic cyp19a1a-eGFP zebrafish (vol 220, 105403, 2020)
errAQUATIC TOXICOLOGY
IF4.3
err2022-06-01
err0
errOAAI
errDe Oliveira, Julie; Chadili, Edith; Piccini, Benjamin; Turies, Cyril; Maillot-Marechal, Emmanuelle; Palluel, Olivier; Pardon, Patrick; Budzinski, Helene; Cousin, Xavier; Brion, Francois; Hinfray, Nathalie
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A comparison of behavioral and reproductive parameters between wild-type, transgenic and mutant zebrafish: Could they all be considered the same zebrafish for reglementary assays on endocrine disruption?
errCOMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
IF4.3
err2021-01-01
err5
errOAAI
errDe Oliveira, Julie; Chadili, Edith; Turies, Cyril; Brion, Francois; Cousin, Xavier; Hinfray, Nathalie
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Human and Zebrafish Nuclear Progesterone Receptors Are Differently Activated by Manifold Progestins
errENVIRONMENTAL SCIENCE & TECHNOLOGY
IF11.3
err2020-07-10
err21
PREAI
errGaroche, Clementine; Ait-Aissa, Selim; Boulahtouf, Abdelhay; Creusot, Nicolas; Hinfray, Nathalie; Bourguet, William; Balaguer, Patrick; Brion, Francois
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Refinement of an OECD test guideline for evaluating the effects of endocrine disrupting chemicals on aromatase gene expression and reproduction using novel transgenic cyp19a1a-eGFP zebrafish
errAQUATIC TOXICOLOGY
IF4.3
err2020-03-01
err13
errOAAI
errDe Oliveira, Julie; Chadili, Edith; Piccini, Benjamin; Turies, Cyril; Maillot-Marechal, Emmanuelle; Palluel, Olivier; Pardon, Patrick; Budzinski, Helene; Cousin, Xavier; Brion, Francois; Hinfray, Nathalie
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Additive effects of levonorgestrel and ethinylestradiol on brain aromatase (cyp19a1b) in zebrafish specific in vitro and in vivo bioassays
errTOXICOLOGY AND APPLIED PHARMACOLOGY
IF3.4
err2016-09-01
err20
errOAAI
errHinfray, N.; Tebby, C.; Garoche, C.; Piccini, B.; Bourgine, G.; Ait-Aissa, S.; Kah, O.; Pakdel, F.; Brion, F.
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Several synthetic progestins disrupt the glial cell specific-brain aromatase expression in developing zebra fish
errTOXICOLOGY AND APPLIED PHARMACOLOGY
IF3.4
err2016-08-01
err28
errOAAI
errCano-Nicolau, Joel; Garoche, Clementine; Hinfray, Nathalie; Pellegrini, Elisabeth; Boujrad, Noureddine; Pakdel, Farzad; Kah, Olivier; Brion, Francois
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Cyp17a1 and Cyp19a1 in the zebrafish testis are differentially affected by oestradiol
errJOURNAL OF ENDOCRINOLOGY
IF3.9
err2013-01-02
err42
errOAAI
errHinfray, Nathalie; Nobrega, Rafael Henrique; Caulier, Morgane; Baudiffier, Damien; Maillot-Marechal, Emmanuelle; Chadili, Edith; Palluel, Olivier; Porcher, Jean-Marc; Schulz, Ruediger; Brion, Francois
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A critical role of follicle-stimulating hormone (Fsh) in mediating the effect of clotrimazole on testicular steroidogenesis in adult zebrafish
errTOXICOLOGY
IF4.6
err2012-08-01
err40
PREAI
errBaudiffier, Damien; Hinfray, Nathalie; Vosges, Melanie; Creusot, Nicolas; Chadili, Edith; Porcher, Jean-Marc; Schulz, Rudiger W.; Brion, Francois
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17α-Ethinylestradiol and nonylphenol affect the development of forebrain GnRH neurons through an estrogen receptors-dependent pathway
errREPRODUCTIVE TOXICOLOGY
IF2.8
err2012-04-01
err50
PREAI
errVosges, Melanie; Kah, Olivier; Hinfray, Nathalie; Chadili, Edith; Le Page, Yann; Combarnous, Yves; Porcher, Jean-Marc; Brion, Francois
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Adverse effects in wild fish living downstream from pharmaceutical manufacture discharges
errENVIRONMENT INTERNATIONAL
IF9.7
err2011-11-01
err141
errOAAI
errSanchez, Wilfried; Sremski, William; Piccini, Benjamin; Palluel, Olivier; Maillot-Marechal, Emmanuelle; Betoulle, Stephane; Jaffal, Ali; Ait-Aissa, Selim; Brion, Francois; Thybaud, Eric; Hinfray, Nathalie; Porcher, Jean-Marc
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Brain cytochrome P450 aromatase activity in roach (Rutilus rutilus): Seasonal variations and impact of environmental contaminants
errAQUATIC TOXICOLOGY
IF4.3
err2011-10-01
err13
PREAI
errGeraudie, Perrine; Hinfray, Nathalie; Gerbron, Marie; Porcher, Jean-Marc; Brion, Francois; Minier, Christophe
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Endocrine disruption in wild populations of chub (Leuciscus cephalus) in contaminated French streams
errSCIENCE OF THE TOTAL ENVIRONMENT
IF8
err2010-04-01
err42
errOAAI
errHinfray, Nathalie; Palluel, Olivier; Piccini, Benjamin; Sanchez, Wilfried; Ait-Aissa, Selim; Noury, Patrice; Gomez, Elena; Geraudie, Perrine; Minier, Christophe; Brion, Francois; Porcher, Jean-Marc
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Oestrogen-induced androgen insufficiency results in a reduction of proliferation and differentiation of spermatogonia in the zebrafish testis
errJOURNAL OF ENDOCRINOLOGY
IF3.9
err2009-05-05
err47
errOAAI
errde Waal, Paul P.; Leal, Marcelo C.; Garcia-Lopez, Angel; Liarte, Sergio; de Jonge, Hugo; Hinfray, Nathalie; Brion, Francois; Schulz, Rudiger W.; Bogerd, Jan
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Research Directions

No research directions
Co-authors
Cooperation Journals
B
Beate I. Escher
H-index: 91 · Papers: 510
R
Robin Lovell‐Badge
H-index: 88 · Papers: 348
H
Hélène Budzinski
H-index: 80 · Papers: 781
H
Helmut Segner
H-index: 73 · Papers: 410
M
Matthias Liess
H-index: 68 · Papers: 274
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