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Brain-Resident MAIT Cells Infiltrate GL261 Tumors, and Activated MAIT Cell Signatures Are Associated With Improved Outcomes in Glioma Eddy, Eleanor M.; Khan, Md Abdullah Al Kamran; Patton, Timothy; Moi, Davide; Wang, Huimeng; Le, Jeremy P.; Souter, Michael N. T.; Nelson, Adam G.; Dewar, Phoebe M.; Li, Shihan; McCluskey, James; Mazzieri, Roberta; Dolcetti, Riccardo; Chen, Zhenjun; Barrow, Alexander D.; Corbett, Alexandra J. Share Save
Adenoviral Inciting Antigen and Somatic Hypermutation in VITT Wang, Jing Jing; Schonborn, Linda; Warkentin, Theodore E.; Muller, Luisa; Thiele, Thomas; Ulm, Lena; Volker, Uwe; Ameling, Sabine; Franzenburg, Soren; Kaderali, Lars; Tzvetkova, Ana; Colella, Alex; Chataway, Tim; Tan, Chee Wee; Armour, Bridie; Troelnikov, Alexander; Rutten, Lucy; Mccluskey, James; Zahn, Roland; Gordon, Tom P.; Greinacher, Andreas Share Save
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MAIT cell plasticity enables functional adaptation that drives antibacterial immune protection Wang, Huimeng; Souter, Michael N. T.; Moreira, Marcela de Lima; Li, Shihan; Zhou, Yuchen; Nelson, Adam G.; Yu, Jinhan; Meehan, Lucy J.; Meehan, Bronwyn S.; Eckle, Sidonia B. G.; Lee, Hyun Jae; Schroeder, Jan; Haque, Ashraful; Mak, Jeffrey Y. W.; Fairlie, David P.; Mccluskey, James; Wang, Zhongfang; Chen, Zhenjun; Corbett, Alexandra J. Share Save
MR1 presents vitamin B6-related compounds for recognition by MR1-reactive T cells Mcinerney, Mitchell P.; Awad, Wael; Souter, Michael N. T.; Kang, Yang; Wang, Carl J. H.; Poa, Kean Chan Yew; Abdelaal, Mohamed R.; Le, Ngoc H.; Shepherd, Chloe M.; Mcneice, Conor; Meehan, Lucy J.; Nelson, Adam G.; Raynes, Jeremy M.; Mak, Jeffrey Y. W.; Mccluskey, James; Chen, Zhenjun; Ang, Ching-Seng; Fairlie, David P.; Le Nours, Jerome; Illing, Patricia T.; Rossjohn, Jamie; Purcell, Anthony W. Share Save
Potent Immunomodulators Developed from an Unstable Bacterial Metabolite of Vitamin B2 Biosynthesis Mak, Jeffrey Y. W.; Rivero, Ryan J. D.; Hoang, Huy N.; Lim, Xin Yi; Deng, Jieru; McWilliam, Hamish E. G.; Villadangos, Jose A.; McCluskey, James; Corbett, Alexandra J.; Fairlie, David P. Share Save
MATT cell-MR1 reactivity is highly conserved across multiple divergent species Edmans, Matthew D.; Connelley, Timothy K.; Morgan, Sophie; Pediongco, Troi J.; Jayaraman, Siddharth; Juno, Jennifer A.; Meehan, Bronwyn S.; Dewar, Phoebe M.; Maze, Emmanuel A.; Roos, Eduard O.; Paudyal, Basudev; Mak, Jeffrey Y. W.; Liu, Ligong; Fairlie, David P.; Wang, Huimeng; Corbett, Alexandra J.; McCluskey, James; Benedictus, Lindert; Tchilian, Elma; Klenerman, Paul; Eckle, Sidonia B. G. Share Save
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Synthetic 5-amino-6-D-ribitylaminouracil paired with inflammatory stimuli facilitates MAIT cell expansion in vivo Nelson, Adam G.; Wang, Huimeng; Dewar, Phoebe M.; Eddy, Eleanor M.; Li, Songyi; Lim, Xin Yi; Patton, Timothy; Zhou, Yuchen; Pediongco, Troi J.; Meehan, Lucy J.; Meehan, Bronwyn S.; Mak, Jeffrey Y. W.; Fairlie, David P.; Stent, Andrew W.; Kjer-Nielsen, Lars; Mccluskey, James; Eckle, Sidonia B. G.; Corbett, Alexandra J.; Souter, Michael N. T.; Chen, Zhenjun Share Save
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The allopurinol metabolite, oxypurinol, drives oligoclonal expansions of drug-reactive T cells in resolved hypersensitivity cases and drug-naive healthy donors Mifsud, Nicole A.; Illing, Patricia T.; Ho, Rebecca; Tuomisto, Johanna E.; Fettke, Heidi; Mullan, Kerry A.; McCluskey, James; Rossjohn, Jamie; Vivian, Julian; Reantragoon, Rangsima; Purcell, Anthony W. Share Save
Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients Nissen, S. E. E.; Lincoff, A. M.; Brennan, D.; Ray, K. K. K.; Mason, D.; Kastelein, J. J. P.; Thompson, P. D. D.; Libby, P.; Cho, L.; Plutzky, J.; Bays, H. E. E.; Moriarty, P. M. M.; Menon, V; Grobbee, D. E. E.; Louie, M. J. J.; Chen, C-F; Li, N.; Bloedon, L. A.; Robinson, P.; Horner, M.; Sasiela, W. J. J.; McCluskey, J.; Davey, D.; Fajardo-Campos, P.; Petrovic, P.; Fedacko, J.; Zmuda, W.; Lukyanov, Y.; Nicholls, S. J. J. Share Save
RIPK3 controls MAIT cell accumulation during development but not during infection Patton, Timothy; Zhao, Zhe; Lim, Xin Yi; Eddy, Eleanor; Wang, Huimeng; Nelson, Adam G.; Ennis, Bronte; Eckle, Sidonia B. G.; Souter, Michael N. T.; Pediongco, Troi J.; Koay, Hui-Fern; Zhang, Jian-Guo; Djajawi, Tirta M.; Louis, Cynthia; Lalaoui, Najoua; Jacquelot, Nicolas; Lew, Andrew M.; Pellicci, Daniel G.; McCluskey, James; Zhan, Yifan; Chen, Zhenjun; Lawlor, Kate E.; Corbett, Alexandra J. Share Save
Suppression of MR1 by human cytomegalovirus inhibits MAIT cell activation Ashley, Caroline L.; McSharry, Brian P.; McWilliam, Hamish E. G.; Stanton, Richard J.; Fielding, Ceri A.; Mathias, Rommel A.; Fairlie, David P.; McCluskey, James; Villadangos, Jose A.; Rossjohn, Jamie; Abendroth, Allison; Slobedman, Barry Share Save
Quantitative affinity measurement of small molecule ligand binding to major histocompatibility complex class-I-related protein 1 MR1 Wang, Carl J. H.; Awad, Wael; Liu, Ligong; Mak, Jeffrey Y. W.; Veerapen, Natacha; Illing, Patricia T.; Purcell, Anthony W.; Eckle, Sidonia B. G.; McCluskey, James; Besra, Gurdyal S.; Fairlie, David P.; Rossjohn, Jamie; Le Nours, Jerome Share Save
The role of mucosal-associated invariant T cells in visceral leishmaniasis Moreira, Marcela de Lima; Borges-Fernandes, Luana Oliveira; Pascoal-Xavier, Marcelo Antonio; Ribeiro, Agata Lopes; Silva Pereira, Victoria Hellena; Pediongco, Troi; da Silva Araujo, Marcio Sobreira; Teixeira-Carvalho, Andrea; de Carvalho, Andrea Lucchesi; Assumpcao Mourao, Maria Vitoria; Campos, Flavia Alves; Borges, Marineide; Carneiro, Mariangela; Chen, Zhenjun; Saunders, Eleanor; McConville, Malcolm; Tsuji, Moriya; McCluskey, James; Martins-Filho, Olindo Assis; Guiomar Eckle, Sidonia Barbara; Alves Coelho-dos-Reis, Jordana Grazziela; Peruhype-Magalhaes, Vanessa Share Save
CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells Souter, Michael N. T.; Awad, Wael; Li, Shihan; Pediongco, Troi J.; Meehan, Bronwyn S.; Meehan, Lucy J.; Tian, Zehua; Zhao, Zhe; Wang, Huimeng; Nelson, Adam; Le Nours, Jerome; Khandokar, Yogesh; Praveena, T.; Wubben, Jacinta; Lin, Jie; Sullivan, Lucy C.; Lovrecz, George O.; Mak, Jeffrey Y. W.; Liu, Ligong; Kostenko, Lyudmila; Kedzierska, Katherine; Corbett, Alexandra J.; Fairlie, David P.; Brooks, Andrew G.; Gherardin, Nicholas A.; Uldrich, Adam P.; Chen, Zhenjun; Rossjohn, Jamie; Godfrey, Dale I.; McCluskey, James; Pellicci, Daniel G.; Eckle, Sidonia B. G. Share Save
The balance of interleukin-12 and interleukin-23 determines the bias of MAIT1 versus MAIT17 responses during bacterial infection Wang, Huimeng; Nelson, Adam G.; Wang, Bingjie; Zhao, Zhe; Lim, Xin Yi; Shi, Mai; Meehan, Lucy J.; Jia, Xiaoxiao; Kedzierska, Katherine; Meehan, Bronwyn S.; Eckle, Sidonia B. G.; Souter, Michael N. T.; Pediongco, Troi J.; Mak, Jeffrey Y. W.; Fairlie, David P.; McCluskey, James; Wang, Zhongfang; Corbett, Alexandra J.; Chen, Zhenjun Share Save