Not logged in CD49d Expression Identifies a Biologically Distinct Subtype of Chronic Lymphocytic Leukemia with Inferior Progression-Free Survival on BTK Inhibitor Therapy Alsadhan, Anfal; Chen, Jonathan; Gaglione, Erika M.; Underbayev, Chingiz; Tuma, Pamela L.; Tian, Xin; Freeman, Lita A.; Baskar, Sivasubramanian; Nierman, Pia; Soto, Susan; Itsara, Andy; Ahn, Inhye E.; Sun, Clare; Bibikova, Elena; Hartmann, Tanja Nicole; Mhibik, Maissa; Wiestner, Adrian Share Save
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Pharmacodynamic Analysis of BTK Inhibition in Patients with Chronic Lymphocytic Leukemia Treated with Acalabrutinib Alsadhan, Anfal; Cheung, Jean; Gulrajani, Michael; Gaglione, Erika M.; Nierman, Pia; Hamdy, Ahmed; Izumi, Raquel; Bibikova, Elena; Patel, Priti; Sun, Clare; Covey, Todd; Herman, Sarah E. M.; Wiestner, Adrian Share Save
Combined BTK and PI3Kδ Inhibition with Acalabrutinib and ACP-319 Improves Survival and Tumor Control in CLL Mouse Model Niemann, Carsten U.; Mora-Jensen, Helena I.; Dadashian, Eman L.; Krantz, Fanny; Covey, Todd; Chen, Shih-Shih; Chiorazzi, Nicholas; Izumi, Raquel; Ulrich, Roger; Lannutti, Brian J.; Wiestner, Adrian; Herman, Sarah E. M. Share Save
The Bruton Tyrosine Kinase (BTK) Inhibitor Acalabrutinib Demonstrates Potent On-Target Effects and Efficacy in Two Mouse Models of Chronic Lymphocytic Leukemia Herman, Sarah E. M.; Montraveta, Arnau; Niemann, Carsten U.; Mora-Jensen, Helena; Gulrajani, Michael; Krantz, Fanny; Mantel, Rose; Smith, Lisa L.; McClanahan, Fabienne; Harrington, Bonnie K.; Colomer, Dolors; Covey, Todd; Byrd, John C.; Izumi, Raquel; Kaptein, Allard; Ulrich, Roger; Johnson, Amy J.; Lannutti, Brian J.; Wiestner, Adrian; Woyach, Jennifer A. Share Save
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Disruption of in vivo Chronic Lymphocytic Leukemia Tumor-Microenvironment Interactions by Ibrutinib - Findings from an Investigator-Initiated Phase II Study Niemann, Carsten U.; Herman, Sarah E. M.; Maric, Irina; Gomez-Rodriguez, Julio; Biancotto, Angelique; Chang, Betty Y.; Martyr, Sabrina; Stetler-Stevenson, Maryalice; Yuan, Constance M.; Calvo, Katherine R.; Braylan, Raul C.; Valdez, Janet; Lee, Yuh Shan; Wong, Deanna H.; Jones, Jade; Sun, Clare; Marti, Gerald E.; Farooqui, Mohammed Z. H.; Wiestner, Adrian Share Save
Interactions between Ibrutinib and Anti-CD20 Antibodies: Competing Effects on the Outcome of Combination Therapy Skarzynski, Martin; Niemann, Carsten U.; Lee, Yuh Shan; Martyr, Sabrina; Maric, Irina; Salem, Dalia; Stetler-Stevenson, Maryalice; Marti, Gerald E.; Calvo, Katherine R.; Yuan, Constance; Valdez, Janet; Soto, Susan; Farooqui, Mohammed Z. H.; Herman, Sarah E. M.; Wiestner, Adrian Share Save
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ON 01910.Na Is Selectively Cytotoxic for Chronic Lymphocytic Leukemia Cells through a Dual Mechanism of Action Involving PI3K/AKT Inhibition and Induction of Oxidative Stress Chapman, Colby M.; Sun, Xiameng; Roschewski, Mark; Aue, Georg; Farooqui, Mohamed; Stennett, Lawrence; Gibellini, Federica; Arthur, Diane; Perez-Galan, Patricia; Wiestner, Adrian Share Save
Treatment-Induced Oxidative Stress and Cellular Antioxidant Capacity Determine Response to Bortezomib in Mantle Cell Lymphoma Weniger, Marc A.; Rizzatti, Edgar G.; Perez-Galan, Patricia; Liu, Delong; Wang, Qiuyan; Munson, Peter J.; Raghavachari, Nalini; White, Therese; Tweito, Megan M.; Dunleavy, Kieron; Ye, Yihong; Wilson, Wyndham H.; Wiestner, Adrian Share Save
Unique cell surface expression of receptor tyrosine kinase ROR1 in human B-cell chronic lymphocytic leukemia Baskar, Sivasubramanian; Kwong, Kayin; Hofer, Thomas; Levy, Jessica M.; Kennedy, Michael G.; Lee, Elinor; Staudt, Louis M.; Wilson, Wyndham H.; Wiestner, Adrian; Rader, Christoph Share Save